Boiling point	208.0±25.0 ºC (760 Tor
Flash point	79.6±23.2 ºC, 计算值*
Density	1.31±0.1 g/cm3 (20 ºC

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Source	SDS/MSDS Samples
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Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

Determination of ginkgolide A, B, and bilobalide in biloba L. extracts by microdialysis-HPLCChiu L-H, et al. Analytical and Bioanalytical Chemistry, 379(3), 445-448 (2004) Theoretical calculations of carbon-hydrogen spin-spin coupling constants.Leonid B Krivdin Progress in nuclear magnetic resonance spectroscopy, 108, 17-73 (2018-12-13) HPLC determination of certain flavonoids and terpene lactones in selected Ginkgo biloba L. phytopharmaceuticals.Mostafa K Mesbah et al.Farmaco (Societa chimica italiana : 1989), 60(6-7), 583-590 (2005-06-07) [Effects of ginkgolide B on proliferation, phagocytosis, NO and ROS production of murine peritoneal macrophages in vitro].Xiao-dong Wang et al.Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 28(1), 4-7 (2012-01-11) Pharmacological action and mechanisms of ginkgolide B.Shi-hai Xia et al.Chinese medical journal, 120(10), 922-928 (2007-06-05) Ginkgo may prevent genetic-associated ovarian cancer risk: multiple biomarkers and anticancer pathways induced by ginkgolide B in BRCA1-mutant ovarian epithelial cells.Wei Jiang et al.European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 20(6), 508-517 (2011-08-23) [Study on the pharmacokinetics of ginkgolide B for injection in rats].Xian-Tao Zhang et al.Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 35(3), 430-433 (2012-08-11) The CNS effects of Ginkgo biloba extracts and ginkgolide B.Karyn M Maclennan et al.Progress in neurobiology, 67(3), 235-257 (2002-08-10) Inhibition of NF-κB activation is associated with anti-inflammatory and anti-apoptotic effects of Ginkgolide B in a mouse model of cerebral ischemia/reperfusion injury.Jin-Hua Gu et al.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 47(4), 652-660 (2012-08-02) Therapeutic neuroprotective effects of ginkgolide B on cortex and basal ganglia in a rat model of transient focal ischemia.Peng Lv et al.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 44(3), 235-240 (2011-08-23) Proofs of involvement of PAF-acether in various immune disorders using BN 52021 (ginkgolide B): a powerful PAF-acether antagonist isolated from Ginkgo biloba L.P Braquet Advances in prostaglandin, thromboxane, and leukotriene research, 16, 179-198 (1986-01-01) A novel anti-inflammatory role for ginkgolide B in asthma via inhibition of the ERK/MAPK signaling pathway.Xiao Chu et al.Molecules (Basel, Switzerland), 16(9), 7634-7648 (2011-09-09) Pharmacokinetics of ginkgolide B injection in beagle dogs.H Song et al.Arzneimittel-Forschung, 62(12), 595-598 (2012-10-25) Effects of Ginkgo biloba constituents on fruit-infesting behavior of codling moth (Cydia pomonella) in apples.Maciej A Pszczolkowski et al.Journal of agricultural and food chemistry, 59(20), 10879-10886 (2011-09-13) Nutraceutical preparations in childhood migraine prophylaxis: effects on headache outcomes including disability and behaviour.Maria Esposito et al.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 33(6), 1365-1368 (2012-03-23) Ginkgolide B inhibits renal cyst development in in vitro and in vivo cyst models.Hong Zhou et al.American journal of physiology. Renal physiology, 302(10), F1234-F1242 (2012-02-18) Different neuroprotective responses of Ginkgolide B and bilobalide, the two Ginkgo components, in ischemic rats with hyperglycemia.Menghao Huang et al.European journal of pharmacology, 677(1-3), 71-76 (2011-12-27) Ginkgolide B reduces atherogenesis and vascular inflammation in ApoE(-/-) mice.Xiyun Liu et al.PloS one, 7(5), e36237-e36237 (2012-06-05) Effect of Natural Phenolics on Pharmacokinetic Modulation of Bedaquiline in Rat to Assess the Likelihood of Potential Food-Drug Interaction.Pankul Kotwal et al.Journal of agricultural and food chemistry, 68(5), 1257-1265 (2020-01-14) Validated LC-MS-MS method for the determination of prodrug of ginkgolide B in rat plasma and brain: application to pharmacokinetic study.Yuan Yuan et al.Journal of chromatographic science, 51(3), 266-272 (2012-08-31) Ginkgolide B reduces neuronal cell apoptosis in the hemorrhagic rat brain: possible involvement of Toll-like receptor 4/nuclear factor-kappa B pathway.Yue-Yu Hu et al.Journal of ethnopharmacology, 137(3), 1462-1468 (2011-09-01) Use of ginkgolide B and a ginkgolide-activated response element to control gene transcription: example of the adrenocortical peripheral-type benzodiazepine receptor.Hakima Amri et al.Cellular and molecular biology (Noisy-le-Grand, France), 48(6), 633-639 (2002-10-25) [Pharmacokinetics of ginkgolides sustained-release tablet].Miaomiao Jin et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 36(8), 1011-1014 (2011-08-04) In vitro suppression of lymphocyte activation in patients with seasonal allergic rhinitis and pollen-related asthma by cetirizine or azelastine in combination with ginkgolide B or astaxanthin.Fadia F Mahmoud et al.Acta physiologica Hungarica, 99(2), 173-184 (2012-08-02) [Study on pharmacokinetics of ginkgolide B injection in Beagle dogs].Xian-tao Zhang et al.Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 35(5), 762-765 (2012-12-12) Ginkgolide B preconditioning on astrocytes promotes neuronal survival in ischemic injury via up-regulating erythropoietin secretion.Xiaomei Wu et al.Neurochemistry international, 62(2), 157-164 (2012-12-04) Ginkgolide B promotes cell growth in endothelial progenitor cells through miR-126 and the Akt signaling pathway.Jing Chang et al.Molecular medicine reports, 16(4), 5627-5632 (2017-08-30) Complete 1H NMR spectral analysis of ten chemical markers of Ginkgo biloba.José G Napolitano et al.Magnetic resonance in chemistry : MRC, 50(8), 569-575 (2012-06-26) Effects of Gut Microbiota on the Bioavailability of Bioactive Compounds from Ginkgo Leaf Extracts.Min Sun Choi et al.Metabolites, 9(7) (2019-07-10) Premenstrual syndrome and migraine.Gianni Allais et al.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 33 Suppl 1, S111-S115 (2012-06-01) Protective effect of ginkgolide B against acute spinal cord injury in rats and its correlation with the Jak/STAT signaling pathway.Yongxing Song et al.Neurochemical research, 38(3), 610-619 (2013-01-01) Ginkgolic acid inhibits HIV protease activity and HIV infection in vitro.Jian-Ming Lü et al.Medical science monitor : international medical journal of experimental and clinical research, 18(8), BR293-BR298 (2012-08-01) Ginkgolide B reduces neuronal cell apoptosis in the traumatic rat brain: possible involvement of toll-like receptor 4 and nuclear factor kappa B pathway.Wen-Hua Yu et al.Phytotherapy research : PTR, 26(12), 1838-1844 (2012-03-17) The pharmacokinetics and conversion of the lactone to the carboxylate forms of ginkgolide B in rat plasma.Dian-Lei Wang et al.Journal of Asian natural products research, 15(4), 337-343 (2013-02-21) Mechanistic evaluation of Ginkgo biloba leaf extract-induced genotoxicity in L5178Y cells.Haixia Lin et al.Toxicological sciences : an official journal of the Society of Toxicology, 139(2), 338-349 (2014-03-07) Ginkgolide B produced endophytic fungus (Fusarium oxysporum) isolated from Ginkgo biloba.Yuna Cui et al.Fitoterapia, 83(5), 913-920 (2012-04-28)

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