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5-Chloro-1-(3-chlorophenyl)-1H-pyrazole-4-carboxylic acid ethyl ester | CAS:98534-74-8
5-Chloro-1-(3-chlorophenyl)-1H-pyrazole-4-carboxylic acid ethyl ester
  • Name:5-Chloro-1-(3-chlorophenyl)-1H-pyrazole-4-carboxylic acid ethyl ester
  • CAS:98534-74-8
  • Synonyms:
  • Molecular Formula:C12H10Cl2N2O2
  • Molecular Weight:285.13
  • EINESC:

Description

Properties

Melting point 55-57 ºC
Density 1.38

Safety

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SDS

Source SDS/MSDS Samples
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Articles
Peer-Reviewed Papers
Multiple bio-analytical methods to reveal possible molecular mechanisms of developmental toxicity in zebrafish embryos/larvae exposed to tris(2-butoxyethyl) phosphate.Zhihua Han et al.Aquatic toxicology (Amsterdam, Netherlands), 150, 175-181 (2014-04-02) Assessment of the delayed neurotoxicity of tributyl phosphate, tributoxyethyl phosphate, and dibutylphenyl phosphate.C D Carrington et al.Toxicology and industrial health, 6(3-4), 415-423 (1990-05-01) Estimation of tris(2-butoxyethyl) phosphate in biological fluids: novel intersubject variability in recovery from human serum.G D Anderson et al.Journal of pharmaceutical sciences, 73(12), 1791-1793 (1984-12-01) Drug-protein binding interferences caused by the plasticizer TBEP.J E Devine Clinical biochemistry, 17(6), 345-347 (1984-12-01) Organophosphate flame retardants in the indoor air and dust in cars in Japan.Masahiro Tokumura et al.Environmental monitoring and assessment, 189(2), 48-48 (2017-01-06) Do evacuated blood collection tubes interfere with therapeutic drug monitoring?R Janknegt et al.Pharmaceutisch weekblad. Scientific edition, 5(6), 287-290 (1983-12-16) Concentrations of organophosphorus, polybromobenzene, and polybrominated diphenyl ether flame retardants in human serum, and relationships between concentrations and donor ages.Peng Li et al.Chemosphere, 171, 654-660 (2017-01-06) Levels and distributions of organophosphate flame retardants and plasticizers in sediment from Taihu Lake, China.Shuxia Cao et al.Environmental toxicology and chemistry, 31(7), 1478-1484 (2012-05-04) Organophosphate flame retardants (OPFRs) induce genotoxicity in vivo: A survey on apoptosis, DNA methylation, DNA oxidative damage, liver metabolites, and transcriptomics.Rui Chen et al.Environment international, 130, 104914-104914 (2019-06-22) Induction of electrophysiological and morphological changes in Sprague-Dawley rats fed tributoxyethyl phosphate.S Laham et al.Journal of applied toxicology : JAT, 4(1), 42-48 (1984-02-01) Interference in plasma level measurements of certain drugs due to a plasticizer in Vacutainers.V P Shah et al.Journal of pharmaceutical sciences, 71(10), II-II (1982-10-01) Health complaints and annoyances after moving into a new office building: a multidisciplinary approach including analysis of questionnaires, air and house dust samples.Hans-Peter Hutter et al.International journal of hygiene and environmental health, 209(1), 65-68 (2005-12-24) Occurrence of organophosphate esters in surface water and ground water in Germany.E Fries et al.Journal of environmental monitoring : JEM, 3(6), 621-626 (2002-01-12) Dose-response toxicity studies on tributoxyethyl phosphate orally administered to Sprague-Dawley rats.S Laham et al.American Industrial Hygiene Association journal, 46(8), 442-448 (1985-08-01) Red-top tubes do not displace drug from protein-binding sites.B H Ackerman et al.Pharmacotherapy, 14(1), 126-126 (1994-01-01) Monitoring of the three organophosphate esters TBP, TCEP and TBEP in river water and ground water (Oder, Germany).Elke Fries et al.Journal of environmental monitoring : JEM, 5(2), 346-352 (2003-05-06) Altered drug-serum protein binding in the genetically obese Zucker rat.I H Benedek et al.Journal of pharmaceutical sciences, 74(8), 837-840 (1985-08-01) Organophosphate flame retardants and organosiloxanes in predatory freshwater fish from locations across Canada.Daryl J McGoldrick et al.Environmental pollution (Barking, Essex : 1987), 193, 254-261 (2014-07-27) The effect of the plasticizers TBEP (tris-(2-butoxyethyl)-phosphate) and DEHP (di-(2-ethylhexyl)-phthalate) on beta-adrenergic ligand binding to alpha 1-acid glycoprotein and mononuclear leukocytes.G Sager et al.Biochemical pharmacology, 38(15), 2551-2557 (1989-08-01) Analysis of organophosphorus flame retardants in environmental and biotic matrices using on-line turbulent flow chromatography-liquid chromatography-tandem mass spectrometry.Monica Giulivo et al.Journal of chromatography. A, 1474, 71-78 (2016-11-08) Drug assay interference caused by plasticizer in Vacutainers.V P Shah et al.American journal of hospital pharmacy, 39(9), 1454-1454 (1982-09-01) Influence of lidocaine on plasma protein binding and pharmacokinetics of verapamil in dogs.F M Belpaire et al.Progress in clinical and biological research, 300, 437-440 (1989-01-01) Elucidating toxicological mechanisms of current flame retardants using a bacterial gene profiling assay.Boris V Krivoshiev et al.Toxicology in vitro : an international journal published in association with BIBRA, 29(8), 2124-2132 (2015-09-08) Binding of oxprenolol and propranolol to serum, albumin and alpha 1-acid glycoprotein in man and other species.F M Belpaire et al.Biochemical pharmacology, 33(13), 2065-2069 (1984-07-01) Use of an avian hepatocyte assay and the avian Toxchip Polymerse chain reaction array for testing prioritization of 16 organic flame retardants.Emily Porter et al.Environmental toxicology and chemistry, 33(3), 573-582 (2013-11-26) In vitro endocrine disruption potential of organophosphate flame retardants via human nuclear receptors.Hiroyuki Kojima et al.Toxicology, 314(1), 76-83 (2013-09-21) Subchronic oral toxicity of tributoxyethyl phosphate in the Sprague-Dawley rat.S Laham et al.Archives of environmental health, 40(1), 12-17 (1985-01-01) [Subchronic toxicity study of tributoxyethyl phosphate in Wistar rats].M Saitoh et al.Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences, (112)(112), 27-39 (1994-01-01) Problems in collection of representative samples for determination of tributoxyethyl phosphate in potable water.G L LeBel et al.Journal - Association of Official Analytical Chemists, 66(1), 202-203 (1983-01-01) Gonadal impairment and parental transfer of tris (2-butoxyethyl) phosphate in zebrafish after long-term exposure to environmentally relevant concentrations.Yangyang Huang et al.Chemosphere, 218, 449-457 (2018-11-30) Determination of non-halogenated, chlorinated and brominated organophosphate flame retardants in herring gull eggs based on liquid chromatography-tandem quadrupole mass spectrometry.Da Chen et al.Journal of chromatography. A, 1220, 169-174 (2011-12-22) Increase in the plasma protein binding of weakly basic drugs in carbon tetrachloride-intoxicated rats.N Sugihara et al.Chemical & pharmaceutical bulletin, 39(10), 2671-2673 (1991-10-01) Binding and displacement of basic, acidic and neutral drugs in normal and orosomucoid-deficient plasma.E Pike et al.Clinical pharmacokinetics, 6(5), 367-374 (1981-09-01)
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