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Diethyl sulfone | CAS:597-35-3
Diethyl sulfone
  • Name:Diethyl sulfone
  • CAS:597-35-3
  • Synonyms:NSC 145719
  • Molecular Formula:C4H10O2S
  • Molecular Weight:122.19
  • EINESC:209-898-0

Description

Properties

Melting point 118-119 ºC***
Boiling point 248 ºC****
Flash point 118.4±11.1 ºC, 计算值*
Density 1.3035 g/cm3 (20 ºC)**

Safety

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SDS

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Synthetic Route
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Peer-Reviewed Papers
Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis.Sang Hyun Cho et al.Antimicrobial agents and chemotherapy, 51(4), 1380-1385 (2007-01-11) Quantitation of Chloramphenicol and Nitrofuran Metabolites in Aquaculture Products Using Microwave-Assisted Derivatization, Automated SPE, and LC-MS/MS.Brian T Veach et al.Journal of AOAC International, 98(3), 588-594 (2015-05-31) Antibiotic prophylaxis for urinary tract infection after midurethral sling: a randomized controlled trial.Daniel Jackson et al.Female pelvic medicine & reconstructive surgery, 19(3), 137-141 (2013-04-25) Effect of antibiotics and vehicles on bovine mammary polymorphonuclear leukocyte morphologic features, viability, and phagocytic activity in vitro.S C Nickerson et al.American journal of veterinary research, 46(11), 2259-2265 (1985-11-01) A misguided 'pill in the pocket' approach with flecainide leading to cardiac arrest.Daniel Kiblboeck et al.BMJ case reports, 2012, doi:10-doi:10 (2012-08-29) Martindale: The Extra Pharmacopoeia Martindale: The Extra Pharmacopoeia, 1529-1531 (1996) Oral and parenteral therapeutic options for outpatient urinary infections caused by enterobacteriaceae producing CTX-M extended-spectrum beta-lactamases.Vidhya Prakash et al.Antimicrobial agents and chemotherapy, 53(3), 1278-1280 (2009-01-07) Treatment options for New Delhi metallo-beta-lactamase-harboring enterobacteriaceae.Benjamin A Rogers et al.Microbial drug resistance (Larchmont, N.Y.), 19(2), 100-103 (2013-01-22) [Hepatic injury associated with use of nitrofurantoin].Y Karmon et al.Harefuah, 136(5), 406-408 (2000-07-29) Antibacterial activity and genotypic-phenotypic characteristics of bacteriocin-producing Bacillus subtilis KKU213: potential as a probiotic strain.Nalisa Khochamit et al.Microbiological research, 170, 36-50 (2014-12-03) Physicochemical determinants of human renal clearance.Manthena V S Varma et al.Journal of medicinal chemistry, 52(15), 4844-4852 (2009-05-19) Sex- and age-specific trends in antibiotic resistance patterns of Escherichia coli urinary isolates from outpatients.Jessina C McGregor et al.BMC family practice, 14, 25-25 (2013-02-26) Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.Denis Fourches et al.Chemical research in toxicology, 23(1), 171-183 (2009-12-18) Nitrofurantoin: an update.B A Cunha Obstetrical & gynecological survey, 44(5), 399-406 (1989-05-01) Quantitative study of natural antioxidant systems for cellular nitrofurantoin toxicity.C Michiels et al.Biochimica et biophysica acta, 967(3), 341-347 (1988-12-15) [Antimicrobial therapy with nitroheterocyclic compounds, for example, metronidazole and nitrofurantoin].H Hof Immunitat und Infektion, 16(6), 220-225 (1988-12-01) Neonatal outcomes after gestational exposure to nitrofurantoin.Hedvig Nordeng et al.Obstetrics and gynecology, 121(2 Pt 1), 306-313 (2013-01-25) Mechanism and fitness costs of PR-39 resistance in Salmonella enterica serovar Typhimurium LT2.Maria Pränting et al.Antimicrobial agents and chemotherapy, 52(8), 2734-2741 (2008-06-04) A predictive ligand-based Bayesian model for human drug-induced liver injury.Sean Ekins et al.Drug metabolism and disposition: the biological fate of chemicals, 38(12), 2302-2308 (2010-09-17) Oral treatment options for ambulatory patients with urinary tract infections caused by extended-spectrum-beta-lactamase-producing Escherichia coli.Simon Auer et al.Antimicrobial agents and chemotherapy, 54(9), 4006-4008 (2010-06-30) cIEF for rapid pKa determination of small molecules: a proof of concept.Stéphanie Romand et al.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 63, 14-21 (2014-07-06) Antiprotozoal Activity Profiling of Approved Drugs: A Starting Point toward Drug Repositioning.Marcel Kaiser et al.PloS one, 10(8), e0135556-e0135556 (2015-08-14) Nitrofurantoin-induced lung disease and prophylaxis of urinary tract infections.Yasser Madani et al.Primary care respiratory journal : journal of the General Practice Airways Group, 21(3), 337-341 (2012-07-28) Mutations to Nitrofurantoin and Nitrofurazone Resistance in Escherichia coli K12Anthony S. Breeze and EMMANUEL E. OBASEIKI-EBOR Microbiology, 129, 99-103 (1983) Laboratory detection of MRSA.V Anil Kumar The new microbiologica, 36(2), 207-207 (2013-06-27) Nitrofurantoin. IARC monographs on the evaluation of carcinogenic risks to humans, 50, 211-231 (1990-01-01) The spread of bla OXA-48 and bla OXA-244 carbapenemase genes among Klebsiella pneumoniae, Proteus mirabilis and Enterobacter spp. isolated in Moscow, Russia.Nadezhda K Fursova et al.Annals of clinical microbiology and antimicrobials, 14, 46-46 (2015-11-04) CombiANT: Antibiotic interaction testing made easy.Nikos Fatsis-Kavalopoulos et al.PLoS biology, 18(9), e3000856-e3000856 (2020-09-18) A practical deuterium-free NMR method for the rapid determination of 1-octanol/water partition coefficients of pharmaceutical agents.Huaping Mo et al.Bioorganic & medicinal chemistry letters, 20(22), 6712-6715 (2010-09-25) Nitrofurantoin-induced pulmonary toxicity during pregnancy: a report of a case and review of the literature.K A Boggess et al.Obstetrical & gynecological survey, 51(6), 367-370 (1996-06-01) Laboratory detection of MRSA.V Anil Kumar The new microbiologica, 36(2), 207-207 (2013-06-27) Presence of plasmid-mediated quinolone resistance in Klebsiella pneumoniae isolates possessing blaKPC in the United States.Andrea Endimiani et al.Antimicrobial agents and chemotherapy, 52(7), 2680-2682 (2008-04-23) Oral and parenteral therapeutic options for outpatient urinary infections caused by enterobacteriaceae producing CTX-M extended-spectrum beta-lactamases.Vidhya Prakash et al.Antimicrobial agents and chemotherapy, 53(3), 1278-1280 (2009-01-07) Treatment options for New Delhi metallo-beta-lactamase-harboring enterobacteriaceae.Benjamin A Rogers et al.Microbial drug resistance (Larchmont, N.Y.), 19(2), 100-103 (2013-01-22) Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis.Sang Hyun Cho et al.Antimicrobial agents and chemotherapy, 51(4), 1380-1385 (2007-01-11) DrugBank 3.0: a comprehensive resource for 'omics' research on drugs.Craig Knox et al.Nucleic acids research, 39(Database issue), D1035-D1041 (2010-11-10) Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.Naomi L Kruhlak et al.Toxicology mechanisms and methods, 18(2-3), 217-227 (2008-01-01) QSAR-based solubility model for drug-like compounds.Rafael Gozalbes et al.Bioorganic & medicinal chemistry, 18(19), 7078-7084 (2010-09-03) Survival of bactericidal antibiotic treatment by a persister subpopulation of Listeria monocytogenes.Gitte M Knudsen et al.Applied and environmental microbiology, 79(23), 7390-7397 (2013-09-24) Long-term hepatic memory for hypersensitivity to nitrofurantoin.L A Paiva et al.The American journal of gastroenterology, 87(7), 891-893 (1992-07-01) Antiprotozoal Activity Profiling of Approved Drugs: A Starting Point toward Drug Repositioning.Marcel Kaiser et al.PloS one, 10(8), e0135556-e0135556 (2015-08-14) Microbiology of urinary tract infections in Gaborone, Botswana.Andrew J Renuart et al.PloS one, 8(3), e57776-e57776 (2013-03-08) Antibiotic resistance in urinary tract infections in college students.Ronald P Olson et al.Journal of American college health : J of ACH, 60(6), 471-474 (2012-08-04) Colistin methanesulfonate against multidrug-resistant Acinetobacter baumannii in an in vitro pharmacodynamic model.Lisa A Kroeger et al.Antimicrobial agents and chemotherapy, 51(9), 3431-3433 (2007-06-20) Exposure to nitrofurantoin during the first trimester of pregnancy and the risk for major malformations.Ori Goldberg et al.Journal of clinical pharmacology, 53(9), 991-995 (2013-07-23) Nitrofurantoin-induced lung disease and prophylaxis of urinary tract infections.Yasser Madani et al.Primary care respiratory journal : journal of the General Practice Airways Group, 21(3), 337-341 (2012-07-28) [Pulmonary toxicity resulting from the use of nitrofurantoin].Marieke J M Broes et al.Nederlands tijdschrift voor geneeskunde, 156(44), A4990-A4990 (2012-11-02) Molecular mechanisms of collateral sensitivity to the antibiotic nitrofurantoin.Roderich Roemhild et al.PLoS biology, 18(1), e3000612-e3000612 (2020-01-28) Stereoselective first total synthesis, confirmation of the absolute configuration and bioevaluation of botryolide-E.D Kumar Reddy et al.Bioorganic & medicinal chemistry letters, 21(3), 997-1000 (2011-01-08) Nitrofurantoin-induced chronic active hepatitis.Guy Amit et al.The Israel Medical Association journal : IMAJ, 4(3), 184-186 (2002-03-23) Nitrofurantoin in the treatment of extended-spectrum β-lactamase-producing Escherichia coli-related lower urinary tract infection.Meltem Isikgoz Tasbakan et al.International journal of antimicrobial agents, 40(6), 554-556 (2012-10-16) [Toxic pulmonary and neuronal reactions to nitrofurantoin].F Mihălţan Revista de igiena, medicina muncii, medicina sociala, bacteriologie, virusologie, parazitologie, epidemiologie, pneumoftiziologie. Pneumoftiziologie, 39(1), 51-58 (1990-01-01) A unique megaplasmid contributes to stress tolerance and pathogenicity of an emergent Salmonella enterica serovar Infantis strain.Gili Aviv et al.Environmental microbiology, 16(4), 977-994 (2013-12-11) Part XI. Trimethoprim-sulfamethoxazole, nitrofurantoin, chloramphenicol, metronidazole and tinidazole, rifaximin, and nitazoxanide.Bhanu Sud et al.The Journal of the Oklahoma State Medical Association, 100(7), 267-272 (2007-09-28) Other antimicrobials of interest in the era of extended-spectrum beta-lactamases: fosfomycin, nitrofurantoin and tigecycline.J Garau Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 14 Suppl 1, 198-202 (2007-12-25) Reduced Susceptibility of Proteus mirabilis to triclosan.David J Stickler et al.Antimicrobial agents and chemotherapy, 52(3), 991-994 (2008-01-09) Costs and effects of screening and treating low risk women with a singleton pregnancy for asymptomatic bacteriuria, the ASB study.Brenda M Kazemier et al.BMC pregnancy and childbirth, 12, 52-52 (2012-08-16) Interventions for preventing recurrent urinary tract infection during pregnancy.Caroline Schneeberger et al.The Cochrane database of systematic reviews, 11, CD009279-CD009279 (2012-11-16) Structure-activity relationships of novel heteroaryl-acrylonitriles as cytotoxic and antibacterial agents.Franciszek Saczewski et al.European journal of medicinal chemistry, 43(9), 1847-1857 (2008-01-12) Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).Jenny M Pedersen et al.Journal of medicinal chemistry, 51(11), 3275-3287 (2008-05-07) Anti-tubercular agents. Part IV: Synthesis and antimycobacterial evaluation of nitroheterocyclic-based 1,2,4-benzothiadiazines.Ahmed Kamal et al.Bioorganic & medicinal chemistry letters, 17(19), 5419-5422 (2007-08-19) [Nitrofurantoin--clinical relevance in uncomplicated urinary tract infections].Ingo Stock Medizinische Monatsschrift fur Pharmazeuten, 37(7), 242-248 (2014-07-30) Lysosomal oxidative stress cytotoxicity induced by nitrofurantoin redox cycling in hepatocytes.J Pourahmad et al.Advances in experimental medicine and biology, 500, 261-265 (2002-01-05) Hemolytic reactions to nitrofurantoin in patients with glucose-6-phosphate dehydrogenase deficiency: theory and practice.J E Gait DICP : the annals of pharmacotherapy, 24(12), 1210-1213 (1990-12-01) Incidence of Shiga toxin-producing Escherichia coli serogroups in ruminant's meat.Hassan Momtaz et al.Meat science, 95(2), 381-388 (2013-06-12) vanM, a new glycopeptide resistance gene cluster found in Enterococcus faecium.Xiaogang Xu et al.Antimicrobial 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