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7-Bromo-5-chloro-1H-pyrrolo[2,3-c]pyridine | CAS:945840-69-7
7-Bromo-5-chloro-1H-pyrrolo[2,3-c]pyridine
  • Name:7-Bromo-5-chloro-1H-pyrrolo[2,3-c]pyridine
  • CAS:945840-69-7
  • Synonyms:
  • Molecular Formula:C7H4BrClN2
  • Molecular Weight:231.48
  • EINESC:

Description

Properties

Density 1.878±0.06 g/cm3 (20 º

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Peer-Reviewed Papers
Acetylcholinesterase biosensor based on functionalized surface of carbon nanotubes for monocrotophos detection.Zou Bin et al.Analytical biochemistry, 560, 12-18 (2018-09-03) New cholinesterase inhibitors for Alzheimer's disease: Structure activity relationship, kinetics and molecular docking studies of 1-butanoyl-3-arylthiourea derivatives.Fayaz Ali Larik et al.International journal of biological macromolecules, 116, 144-150 (2018-05-08) Microcalorimetric study of acetylcholine and acetylthiocholine hydrolysis by acetylcholinesterasede Almeida Neves PAA, et al. Advances in Enzyme Research, 5(01), 1-1 (2017) Graveoline Analogs Exhibiting Selective Acetylcholinesterase Inhibitory Activity as Potential Lead Compounds for the Treatment of Alzheimer's Disease.Zeng Li et al.Molecules (Basel, Switzerland), 21(2), 132-132 (2016-01-26) Isolation of Exosomes from Semen for in vitro Uptake and HIV-1 Infection AssaysMadison MN, et al. Bio-protocol, 7(7) (2017) Development of Novel High-Resolution Size-Guided Turbidimetry-Enabled Particle Purification Liquid Chromatography (PPLC): Extracellular Vesicles and Membraneless Condensates in Focus.Hussein Kaddour et al.International journal of molecular sciences, 21(15) (2020-08-01) Discovery of multitarget-directed ligands against Alzheimer's disease through systematic prediction of chemical-protein interactions.Jiansong Fang et al.Journal of chemical information and modeling, 55(1), 149-164 (2014-12-23) Cholinesterase-like organocatalysis by imidazole and imidazole-bearing molecules.Paola Nieri et al.Scientific reports, 8, 45760-45760 (2017-04-04) A novel acetylcholinesterase inhibitor and calcium channel blocker SCR-1693 improves Aβ25-35-impaired mouse cognitive function.Zhengping Zhang et al.Psychopharmacology, 233(4), 599-613 (2015-11-12) Effect of prolonged freezing of semen on exosome recovery and biologic activity.Jennifer L Welch et al.Scientific reports, 7, 45034-45034 (2017-03-25) Identification of New Chromenone Derivatives as Cholinesterase Inhibitors and Molecular Docking Studies.Jamshed Iqbal et al.Medicinal chemistry (Shariqah (United Arab Emirates)), 14(8), 809-817 (2018-02-24) A novel amperometric biosensor based on covalently attached multilayer assemblies of gold nanoparticles, diazo-resins and acetylcholinesterase for the detection of organophosphorus pesticides.Bin Jiang et al.Talanta, 183, 114-121 (2018-03-24) Conformational Complexity and Dynamics in a Muscarinic Receptor Revealed by NMR Spectroscopy.Jun Xu et al.Molecular cell, 75(1), 53-65 (2019-05-20) Development of Novel High-Resolution Size-Guided Turbidimetry-Enabled Particle Purification Liquid Chromatography (PPLC): Extracellular Vesicles and Membraneless Condensates in Focus.Hussein Kaddour et al.International journal of molecular sciences, 21(15) (2020-08-01) Evaluation of Inhibition Efficiency for the Detection of Captan, 2,3,7,8-Tetrachlorodibenzodioxin, Pentachlorophenol and Carbosulfan in Water: An Electrochemical Approach.Noel Nesakumar et al.Bulletin of environmental contamination and toxicology, 96(2), 217-223 (2015-11-28) Synthesis and biological evaluation of potential acetylcholinesterase inhibitors based on a benzoxazine core.Claudio Méndez-Rojas et al.Archiv der Pharmazie, 351(5), e1800024-e1800024 (2018-04-04) New cholinesterase inhibitors for Alzheimer's disease: Structure activity relationship, kinetics and molecular docking studies of 1-butanoyl-3-arylthiourea derivatives.Fayaz Ali Larik et al.International journal of biological macromolecules, 116, 144-150 (2018-05-08) How to extend range linearity in enzyme inhibition-based biosensing assays.Aziz Amine et al.Talanta, 189, 365-369 (2018-08-09) Structural Isomerism and Enhanced Lipophilicity of Pyrithione Ligands of Organoruthenium(II) Complexes Increase Inhibition on AChE and BuChE.Jerneja Kladnik et al.International journal of molecular sciences, 21(16) (2020-08-13) Electrochemical biosensor for methyl parathion based on single-walled carbon nanotube/glutaraldehyde crosslinked acetylcholinesterase-wrapped bovine serum albumin nanocomposites.T H Vignesh Kumar et al.Analytica chimica acta, 1074, 131-141 (2019-06-05) Proteomics Profiling of Autologous Blood and Semen Exosomes from HIV-infected and Uninfected Individuals Reveals Compositional and Functional Variabilities.Hussein Kaddour et al.Molecular & cellular proteomics : MCP, 19(1), 78-100 (2019-11-05) Synthetic analogs of stryphnusin isolated from the marine sponge Stryphnus fortis inhibit acetylcholinesterase with no effect on muscle function or neuromuscular transmission.Lindon W K Moodie et al.Organic & biomolecular chemistry, 14(47), 11220-11229 (2016-11-15) Discovering New Acetylcholinesterase Inhibitors by Mining the Buzhongyiqi Decoction Recipe Data.Lu Cui et al.Journal of chemical information and modeling, 55(11), 2455-2463 (2015-10-29) Specific inhibition of acetylcholinesterase as an approach to decrease muscarinic side effects during myasthenia gravis treatment.Konstantin A Petrov et al.Scientific reports, 8(1), 304-304 (2018-01-13) Dual functional cholinesterase and MAO inhibitors for the treatment of Alzheimer's disease: synthesis, pharmacological analysis and molecular modeling of homoisoflavonoid derivatives.Yali Wang et al.Journal of enzyme inhibition and medicinal chemistry, 31(3), 389-397 (2015-03-24) Electrochemical micro analytical device interfaced with portable potentiostat for rapid detection of chlorpyrifos using acetylcholinesterase conjugated metal organic framework using Internet of things.Shalini Nagabooshanam et al.Scientific reports, 9(1), 19862-19862 (2019-12-29) Quinoline containing chalcone derivatives as cholinesterase inhibitors and their in silico modeling studies.Muhammad Shakil Shah et al.Computational biology and chemistry, 76, 310-317 (2018-08-25) Palladium-copper nanowires-based biosensor for the ultrasensitive detection of organophosphate pesticides.Dandan Song et al.Analytica chimica acta, 982, 168-175 (2017-07-25) Rapid and label-free detection of ochratoxin A and aflatoxin B1 using an optical portable instrument.Fabiana Arduini et al.Talanta, 150, 440-448 (2016-02-04) Silibinin inhibits acetylcholinesterase activity and amyloid β peptide aggregation: a dual-target drug for the treatment of Alzheimer's disease.Songwei Duan et al.Neurobiology of aging, 36(5), 1792-1807 (2015-03-17) Exonuclease I-aided homogeneous electrochemical strategy for organophosphorus pesticide detection based on enzyme inhibition integrated with a DNA conformational switch.Xiuzhong Wang et al.The Analyst, 141(5), 1830-1836 (2016-02-04) On the use of the experimentally determined enzyme inhibition constant as a measure of absolute binding affinity.Fouad H Darras et al.Biochemical and biophysical research communications, 489(4), 451-454 (2017-06-03) Tacrine-propargylamine derivatives with improved acetylcholinesterase inhibitory activity and lower hepatotoxicity as a potential lead compound for the treatment of Alzheimer's disease.Fei Mao et al.Journal of enzyme inhibition and medicinal chemistry, 30(6), 995-1001 (2015-03-21) Disposition and acute toxicity of imidacloprid in female rats after single exposure.Upasana Kapoor et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 68, 190-195 (2014-03-26) Biosensor-assisted selection of optimal parameters for designing molecularly imprinted polymers selective to phosmet insecticide.Nadin Aftim et al.Talanta, 174, 414-419 (2017-07-26) Syncytin proteins incorporated in placenta exosomes are important for cell uptake and show variation in abundance in serum exosomes from patients with preeclampsia.Amandine Vargas et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(8), 3703-3719 (2014-05-09) The P-glycoprotein inhibitor diltiazem-like 8-(4-chlorophenyl)-5-methyl-8-[(2Z)-pent-2-en-1-yloxy]-8H-[1,2,4]oxadiazolo[3,4-c][1,4]thiazin-3-one inhibits esterase activity and H3 histone acetylation.Flavia Cuviello et al.European journal of medicinal chemistry, 164, 1-7 (2018-12-26) Electrochemical acetylcholinesterase biosensor based on ZnO nanocuboids modified platinum electrode for the detection of carbosulfan in rice.Noel Nesakumar et al.Biosensors & bioelectronics, 77, 1070-1077 (2015-11-13) Functionalized polyacrylamide as an acetylcholinesterase-inspired biomimetic device for electrochemical sensing of organophosphorus pesticides.Livia F Sgobbi et al.Biosensors & bioelectronics, 100, 290-297 (2017-09-25) Detection of glycoalkaloids using disposable biosensors based on genetically modified enzymes.Michelle Arredondo Espinoza et al.Analytical biochemistry, 457, 85-90 (2014-04-22) Feeding Preference and Sub-chronic Effects of ZnO Nanomaterials in Honey Bees (Apis mellifera carnica).Gordana Glavan et al.Archives of environmental contamination and toxicology, 72(3), 471-480 (2017-03-09) Cholinesterases inhibition and molecular modeling studies of piperidyl-thienyl and 2-pyrazoline derivatives of chalcones.Muhammad Shakil Shah et al.Biochemical and biophysical research communications, 482(4), 615-624 (2016-11-21) Synthesis and characterization of 1H-phenanthro[9,10-d]imidazole derivatives as multifunctional agents for treatment of Alzheimer's disease.Jinggong Liu et al.Biochimica et biophysica acta, 1840(9), 2886-2903 (2014-05-14) Discorhabdin alkaloids from Antarctic Latrunculia spp. sponges as a new class of cholinesterase inhibitors.Tanja Botić et al.European journal of medicinal chemistry, 136, 294-304 (2017-05-16) An Amperometric Sensor for Thiocholine Based on Cluster-Assembled Zirconia Modified Electrodes.Alexandra Raileanu et al.Journal of nanoscience and nanotechnology, 18(10), 6905-6912 (2018-06-30) Tumor cell migration is inhibited by a novel therapeutic strategy antagonizing the alpha-7 receptor.Chris Pepper et al.Oncotarget, 8(7), 11414-11424 (2017-01-13) An acetylcholinesterase (AChE) biosensor with enhanced solvent resistance based on chitosan for the detection of pesticides.John Warner et al.Talanta, 146, 279-284 (2015-12-24) Neuroprotective effects of quercetin on memory and anxiogenic-like behavior in diabetic rats: Role of ectonucleotidases and acetylcholinesterase activities.Roberto M Maciel et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 84, 559-568 (2016-10-04) Discovery of multitarget-directed ligands against Alzheimer's disease through systematic prediction of chemical-protein interactions.Jiansong Fang et al.Journal of chemical information and modeling, 55(1), 149-164 (2014-12-23) First evidence of cholinesterase-like activity in Basidiomycota.Kristina Sepčić et al.PloS one, 14(4), e0216077-e0216077 (2019-05-01)
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