Melting point	300 ºC

SDS/MSDS	S24/25

Source	SDS/MSDS Samples
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Peer-Reviewed Papers

Structure-activity relationships and molecular docking of thirteen synthesized flavonoids as horseradish peroxidase inhibitors.Reguia Mahfoudi et al.Bioorganic chemistry, 74, 201-211 (2017-08-28) Multistep conversion of para-substituted phenols by phenol hydroxylase and 2,3-dihydroxybiphenyl 1,2-dioxygenase.Yuanyuan Qu et al.Applied biochemistry and biotechnology, 169(7), 2064-2075 (2013-02-02) Improved Laccase Production by Trametes pubescens MB89 in Distillery Wastewaters.P J Strong Enzyme research, 2011, 379176-379176 (2011-12-23) Structure Effect on Antioxidant Activity of Catecholamines toward Singlet Oxygen and Other Reactive Oxygen Species in vitro.Takako Shimizu et al.Journal of clinical biochemistry and nutrition, 47(3), 181-190 (2010-11-26) The Reactivity and Reaction Pathway of Fenton Reactions Driven by Substituted 1,2-Dihydroxybenzenes.Pablo Salgado et al.Environmental science & technology, 51(7), 3687-3693 (2017-03-09) Purification and biochemical characterization of polyphenol oxidases from embryogenic and nonembryogenic cotton (Gossypium hirsutum L.) cells.Tanoh Hilaire Kouakou et al.Applied biochemistry and biotechnology, 158(2), 285-301 (2008-09-17) Antibacterial polyphenols from olive oil mill waste waters.R Capasso et al.The Journal of applied bacteriology, 79(4), 393-398 (1995-10-01) Ultrasmall c(RGDyK)-coated Fe3O4 nanoparticles and their specific targeting to integrin alpha(v)beta3-rich tumor cells.Jin Xie et al.Journal of the American Chemical Society, 130(24), 7542-7543 (2008-05-27) Acquisition of MDMA self-administration: pharmacokinetic factors and MDMA-induced serotonin release.Sarah Bradbury et al.Addiction biology, 19(5), 874-884 (2013-06-15) H-point curve isolation method for determination of catechol in complex unknown mixtures.Masoumeh Hasani et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 96, 563-568 (2012-08-07) Molecular Characterization of White Wines Antioxidant Metabolome by Ultra High Performance Liquid Chromatography High-Resolution Mass Spectrometry.Remy Romanet et al.Antioxidants (Basel, Switzerland), 9(2) (2020-02-06) Enhancement of cutaneous nerve regeneration by 4-methylcatechol in resiniferatoxin-induced neuropathy.Yu-Lin Hsieh et al.Journal of neuropathology and experimental neurology, 67(2), 93-104 (2008-01-26) Agonistic effect of polyunsaturated fatty acids (PUFAs) and its metabolites on brain-derived neurotrophic factor (BDNF) through molecular docking simulation.Umashankar Vetrivel et al.Lipids in health and disease, 11, 109-109 (2012-09-05) Fully biological production of adipic acid analogs from branched catechols.Nicholas S Kruyer et al.Scientific reports, 10(1), 13367-13367 (2020-08-10) Differential in vitro inhibition of polyphenoloxidase from a wild edible mushroom Lactarius salmonicolor.Nurcan Dedeoglu et al.Journal of enzyme inhibition and medicinal chemistry, 24(2), 464-470 (2008-10-03) Evidence consistent with the requirement of cresolase activity for suicide inactivation of tyrosinase.Edward J Land et al.The Tohoku journal of experimental medicine, 216(3), 231-238 (2008-11-07) Nerve sprouting suppresses myocardial I(to) and I(K1) channels and increases severity to ventricular fibrillation in rat.Chongyu Ren et al.Autonomic neuroscience : basic & clinical, 144(1-2), 22-29 (2008-09-27) Biochemical Properties of Polyphenol Oxidases from Ready-to-Eat Lentil (Lens culinaris Medik.) Sprouts and Factors Affecting Their Activities: A Search for Potent Tools Limiting Enzymatic Browning.Małgorzata Sikora et al.Foods (Basel, Switzerland), 8(5) (2019-05-10) Enzymatic and phytochemical stabilization of orange-strawberry-banana beverages by high hydrostatic pressure and mild heat.Zamantha Escobedo-Avellaneda et al.Food science and technology international = Ciencia y tecnologia de los alimentos internacional, 23(2), 185-193 (2016-11-11) Selection for growth on 3-nitrotoluene by 2-nitrotoluene-utilizing Acidovorax sp. strain JS42 identifies nitroarene dioxygenases with altered specificities.Kristina M Mahan et al.Applied and environmental microbiology, 81(1), 309-319 (2014-10-26) Anti-inflammatory activity of Barleria lupulina: Identification of active compounds that activate the Nrf2 cell defense pathway, organize cortical actin, reduce stress fibers, and improve cell junctions in microvascular endothelial cells.Donald R Senger et al.Journal of ethnopharmacology, 193, 397-407 (2016-09-24) Effect of maceration duration on physicochemical characteristics, organic acid, phenolic compounds and antioxidant activity of red wine fromN Kocabey et al.Journal of food science and technology, 53(9), 3557-3565 (2016-10-26) Neurotrophic and antioxidant effects of silymarin comparable to 4-methylcatechol in protection against gentamicin-induced ototoxicity in guinea pigs.Eman I Draz et al.Pharmacological reports : PR, 67(2), 317-325 (2015-02-26) Characterization of polyphenol oxidase from Cape gooseberry (Physalis peruviana L.) fruit.Karent Bravo et al.Food chemistry, 197(Pt A), 185-190 (2015-12-01) 4-methylcatechol inhibits protein oxidation in meat but not disulfide formation.Sisse Jongberg et al.Journal of agricultural and food chemistry, 59(18), 10329-10335 (2011-08-25) Electrochemical synthesis of novel 1,3-indandione derivatives and evaluation of their antiplatelet aggregation activities.Salimeh Amidi et al.Iranian journal of pharmaceutical research : IJPR, 12(Suppl), 91-103 (2013-11-20) Characterization of Metabolic Patterns in Mouse Oocytes during Meiotic Maturation.Ling Li et al.Molecular cell, 80(3), 525-540 (2020-10-18) Interleukin-6 protects against paclitaxel, cisplatin and vincristine-induced neuropathies without impairing chemotherapeutic activity.Noelle Callizot et al.Cancer chemotherapy and pharmacology, 62(6), 995-1007 (2008-02-14) Non-Equilibrium Potential Responses towards Neutral Orcinol Using All-Solid-State Potentiometric Sensors Integrated with Molecularly Imprinted Polymers.Saad S M Hassan et al.Polymers, 11(8) (2019-07-28) Phenolic composition of 91 Australian apple varieties: towards understanding their health attributes.Catherine P Bondonno et al.Food & function, 11(8), 7115-7125 (2020-08-04) Antioxidant activity from inactivated yeast: Expanding knowledge beyond the glutathione-related oxidative stability of wine.Florian Bahut et al.Food chemistry, 325, 126941-126941 (2020-05-11) Determination of nicotine and four metabolites in the serum of smokers by high-performance liquid chromatography with ultraviolet detection.P Zuccaro et al.Journal of chromatography, 621(2), 257-261 (1993-11-24) Linear pharmacokinetics of 3,4-methylenedioxypyrovalerone (MDPV) and its metabolites in the rat: relationship to pharmacodynamic effects.Sebastien Anizan et al.Addiction biology, 21(2), 339-347 (2014-12-06) Quantification of urinary o,o'-dityrosine, a biomarker for oxidative damage to proteins, by high performance liquid chromatography with triple quadrupole tandem mass spectrometry. A comparison with ion-trap tandem mass spectrometry.Hilmi Orhan et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 827(1), 104-108 (2005-05-10) Characterization of catechol 2,3-dioxygenase from Planococcus sp. strain S5 induced by high phenol concentration.Katarzyna Hupert-Kocurek et al.Acta biochimica Polonica, 59(3), 345-351 (2012-07-25) Characterization of catechol derivative removal by lignin peroxidase in aqueous mixture.Shaul Cohen et al.Bioresource technology, 100(7), 2247-2253 (2008-12-23) A single-step extraction method for the determination of nicotine and cotinine in Jordanian smokers' blood and urine samples by RP-HPLC and GC-MS.Adnan M Massadeh et al.Journal of chromatographic science, 47(2), 170-177 (2009-02-19) Quantitative analysis of catechol and 4-methylcatechol in human urine.S G Carmella et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 20(5), 587-590 (1982-10-01) Verifying the botanical authenticity of commercial tannins through sugars and simple phenols profiles.Mario Malacarne et al.Food chemistry, 206, 274-283 (2016-04-05) Urinary metabolites of flavonoids and hydroxycinnamic acids in humans after application of a crude extract from Equisetum arvense.E U Graefe et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 6(4), 239-246 (1999-12-10) Genetic diversity of catechol 1,2-dioxygenase in the fecal microbial metagenome.Bo Xu et al.Journal of basic microbiology, 57(10), 883-895 (2017-07-27) Tetrahydrobiopterin restores endothelial function in long-term smokers.S Ueda et al.Journal of the American College of Cardiology, 35(1), 71-75 (2000-01-15) Characterisation by liquid chromatography coupled to electrospray ionisation ion trap mass spectrometry of phloroglucinol and 4-methylcatechol oxidation products to study the reactivity of epicatechin in an apple juice model system.Pascal Poupard et al.Journal of chromatography. A, 1179(2), 168-181 (2007-12-21) Composition of pigments and colour changes in green table olives related to processing type.Eva Ramírez et al.Food chemistry, 166, 115-124 (2014-07-24) Simultaneous analysis of nicotine, nicotine metabolites, and tobacco alkaloids in serum or urine by tandem mass spectrometry, with clinically relevant metabolic profiles.Thomas P Moyer et al.Clinical chemistry, 48(9), 1460-1471 (2002-08-27) Development of low-cost paper-based biosensor of polyphenol oxidase for detection of phenolic contaminants in water and clinical samples.Rubia Noori et al.Environmental science and pollution research international, 27(24), 30081-30092 (2020-05-25) Comparison of antioxidative capacities and inhibitory effects on cholesterol biosynthesis of quercetin and potential metabolites.G Glässer et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 9(1), 33-40 (2002-04-02) Kinetic investigation of the trapping of Nε-(carboxymethyl)lysine by 4-methylbenzoquinone: A new mechanism to control Nε-(carboxymethyl)lysine levels in foods.Yuting Li et al.Food chemistry, 244, 25-28 (2017-11-10) Influence of pH on the antioxidant phenols solubilised from hydrothermally treated olive oil by-product (alperujo).Fátima Rubio-Senent et al.Food chemistry, 219, 339-345 (2016-10-22) 4-Methylcatechol-induced heme oxygenase-1 exerts a protective effect against oxidative stress in cultured neural stem/progenitor cells via PI3 kinase/Akt pathway.Yoshiko Furukawa et al.Biomedical research (Tokyo, Japan), 31(1), 45-52 (2010-03-06) Studies on drug metabolism by use of isotopes XXVI: Determination of urinary metabolites of rutin in humans.S Baba et al.Journal of pharmaceutical sciences, 70(7), 780-782 (1981-07-01) Magnetically responsive peptide coacervates for dual hyperthermia and chemotherapy treatments of liver cancer.Zhi Wei Lim et al.Acta biomaterialia, 110, 221-230 (2020-05-19) Characterization of microbial metabolism of Syrah grape products in an in vitro colon model using targeted and non-targeted analytical approaches.Anna-Marja Aura et al.European journal of nutrition, 52(2), 833-846 (2012-06-16) Cellular apoptosis and cytotoxicity of phenolic compounds: a quantitative structure-activity relationship study.Cynthia D Selassie et al.Journal of medicinal chemistry, 48(23), 7234-7242 (2005-11-11) Polymeric substances for the removal of ochratoxin A from red wine followed by computational modeling of the complexes formed.Verónica Carrasco-Sánchez et al.Food chemistry, 265, 159-164 (2018-06-10) Iron traffics in circulation bound to a siderocalin (Ngal)-catechol complex.Guanhu Bao et al.Nature chemical biology, 6(8), 602-609 (2010-06-29) Flavanols react preferentially with quinones through an electron transfer reaction, stimulating rather than preventing wine browning.Lingjun Ma et al.Analytica chimica acta, 1039, 162-171 (2018-10-17) The innate immune and systemic response in honey bees to a bacterial pathogen, Paenibacillus larvae.Queenie W T Chan et al.BMC genomics, 10, 387-387 (2009-08-22) Nicotine exposure can be detected in cerebrospinal fluid of active and passive smokers.Ahmad H Malkawi et al.Journal of pharmaceutical and biomedical analysis, 49(1), 129-132 (2008-11-28) Effects of 4-methylcatechol on spatial memory and depression.Miao-Kun Sun et al.Neuroreport, 19(3), 355-359 (2008-02-28) Intracerebroventricular 4-methylcatechol (4-MC) ameliorates chronic pain associated with depression-like behavior via induction of brain-derived neurotrophic factor (BDNF).Kayoko Fukuhara et al.Cellular and molecular neurobiology, 32(6), 971-977 (2011-12-27) Rutin metabolites: novel inhibitors of nonoxidative advanced glycation end products.Srinath Pashikanti et al.Free radical biology & medicine, 48(5), 656-663 (2009-12-09) The effect of the buffering capacity of the supporting electrolyte on the electrochemical oxidation of dopamine and 4-methylcatechol in aqueous and nonaqueous solvents.Shanshan Chen et al.Chemistry, an Asian journal, 6(6), 1492-1499 (2011-05-11) Simultaneous determination of mercapturic acids derived from ethylene oxide (HEMA), propylene oxide (2-HPMA), acrolein (3-HPMA), acrylamide (AAMA) and N,N-dimethylformamide (AMCC) in human urine using liquid chromatography/tandem mass spectrometry.Thomas Schettgen et al.Rapid communications in mass spectrometry : RCM, 22(17), 2629-2638 (2008-07-31) 4-Methylcatechol-induced oxidative stress induces intrinsic apoptotic pathway in metastatic melanoma cells.Florastina Payton et al.Biochemical pharmacology, 81(10), 1211-1218 (2011-03-23) Measurement of urinary excretion of 5-hydroxymethyluracil in human by GC/NICI/MS: correlation with cigarette smoking, urinary TBARS and etheno DNA adduct.Hauh-Jyun Candy Chen et al.Toxicology letters, 155(3), 403-410 (2005-01-15) A regulatory domain in the K2P2.1 (TREK-1) carboxyl-terminal allows for channel activation by monoterpenes.Eden Arazi et al.Molecular and cellular neurosciences, 105, 103496-103496 (2020-04-23) Interactions of Insoluble Residue from Enzymatic Hydrolysis of Brewer's Spent Grain with Intestinal Microbiota in Mice.Johanna Maukonen et al.Journal of agricultural and food chemistry, 65(18), 3748-3756 (2017-04-27) 4-Methlycatechol prevents NGF/p75(NTR)-mediated apoptosis via NGF/TrkA system in pancreatic β cells.Selda Gezginci-Oktayoglu et al.Neuropeptides, 45(2), 143-150 (2011-02-08) Effects of 4-methylcatechol on skin reinnervation: promotion of cutaneous nerve regeneration after crush injury.Yu-Lin Hsieh et al.Journal of neuropathology and experimental neurology, 68(12), 1269-1281 (2009-11-17) Oxidation of 4-methylcatechol: implications for the oxidation of catecholamines.Guoliang Li et al.Biochemistry, 46(23), 6978-6983 (2007-05-17) Characteristics of a Recombinant 2,3-Dihydroxybiphenyl 1,2-Dioxygenase fromNari Lee et al.Indian journal of microbiology, 56(4), 467-475 (2016-10-28) Simultaneous quantitative analysis of polyphenolic compounds in human plasma by liquid chromatography tandem mass spectrometry.Armaghan Shafaei et al.Journal of separation science, 42(18), 2909-2921 (2019-07-12) Kinetic cooperativity of tyrosinase. A general mechanism.Jose Luis Muñoz-Muñoz et al.Acta biochimica Polonica, 58(3), 303-311 (2011-09-03) Almond consumption reduces oxidative DNA damage and lipid peroxidation in male smokers.Ning Li et al.The Journal of nutrition, 137(12), 2717-2722 (2007-11-22) Monoterpenes Differently Regulate Acid-Sensitive and Mechano-Gated K2P Channels.Eden Arazi et al.Frontiers in pharmacology, 11, 704-704 (2020-06-09) Inhibitory Effects of Quercetin and Its Human and Microbial Metabolites on Xanthine Oxidase Enzyme.Violetta Mohos et al.International journal of molecular sciences, 20(11) (2019-06-05) Construction of chimeric catechol 2,3-dioxygenase exhibiting improved activity against the suicide inhibitor 4-methylcatechol.Akiko Okuta et al.Applied and environmental microbiology, 70(3), 1804-1810 (2004-03-10) Testing the Pharmacokinetic Interactions of 24 Colonic Flavonoid Metabolites with Human Serum Albumin and Cytochrome P450 Enzymes.Violetta Mohos et al.Biomolecules, 10(3) (2020-03-12) A Bph-Like Nitroarene Dioxygenase Catalyzes the Conversion of 3-Nitrotoluene to 3-Methylcatechol by Rhodococcus sp. Strain ZWL3NT.Yi-Zhou Gao et al.Applied and environmental microbiology, 86(4) (2019-12-08) Purification and partial biochemical characterization of polyphenol oxidase from mamey (Pouteria sapota).Gisela Palma-Orozco et al.Phytochemistry, 72(1), 82-88 (2010-11-23)

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