Melting point	2.5-3.5 ºC
Specific optical rotation	24 º (c=2, in isooctane 25
Water Solubility	Insoluble
Boiling point	200-220 ºC (0.07501 mmHg)
Density	0.95
Refractive index	1.505-1.507

SDS/MSDS	S23;S24/25

Source	SDS/MSDS Samples
没有数据	没有数据

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Articles

Peer-Reviewed Papers

Mechanism of chemical degradation and determination of solubility by kinetic modeling of the highly unstable sesquiterpene lactone nobilin in different media.Ursula Thormann et al.Journal of pharmaceutical sciences, 103(10), 3139-3152 (2014-09-02) An in vitro digestion test that reflects rat intestinal conditions to probe the importance of formulation digestion vs first pass metabolism in Danazol bioavailability from lipid based formulations.Mette U Anby et al.Molecular pharmaceutics, 11(11), 4069-4083 (2014-09-30) Predicting the oral pharmacokinetic profiles of multiple-unit (pellet) dosage forms using a modeling and simulation approach coupled with biorelevant dissolution testing: case example diclofenac sodium.Atsushi Kambayashi et al.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 87(2), 236-243 (2014-01-28) Toward the establishment of standardized in vitro tests for lipid-based formulations, part 4: proposing a new lipid formulation performance classification system.Hywel D Williams et al.Journal of pharmaceutical sciences, 103(8), 2441-2455 (2014-07-06) Development of novel docetaxel phospholipid nanoparticles for intravenous administration: quality by design approach.Dharmendra K Yadav et al.AAPS PharmSciTech, 16(4), 855-864 (2015-01-15) Sensing of triacylglycerol in the gut: different mechanisms for fatty acids and 2-monoacylglycerol.Karen Kleberg et al.The Journal of physiology, 593(8), 2097-2109 (2015-02-03) 'Stealth' lipid-based formulations: poly(ethylene glycol)-mediated digestion inhibition improves oral bioavailability of a model poorly water soluble drug.Orlagh M Feeney et al.Journal of controlled release : official journal of the Controlled Release Society, 192, 219-227 (2014-07-25) Lipid-based formulations solidified via adsorption onto the mesoporous carrier Neusilin® US2: effect of drug type and formulation composition on in vitro pharmaceutical performance.Hywel D Williams et al.Journal of pharmaceutical sciences, 103(6), 1734-1746 (2014-04-18) Lipidic dispersion to reduce food dependent oral bioavailability of fenofibrate: In vitro, in vivo and in silico assessments.Joseph P O'Shea et al.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 96, 207-216 (2015-07-29) Non-linear increases in danazol exposure with dose in older vs. younger beagle dogs: the potential role of differences in bile salt concentration, thermodynamic activity, and formulation digestion.Mette U Anby et al.Pharmaceutical research, 31(6), 1536-1552 (2014-01-31)

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