Melting point	220 ºC
Water Solubility	5 g/L (20 ºC)
Flash point	200 ºC
Density	1.56

Symbol(GHS)	Xi;N
Hazard Codes	R36/37/38;R51/53
SDS/MSDS	S26;S37/39;S61

Source	SDS/MSDS Samples
没有数据	没有数据

Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

Exposure to toluenediamines from polyurethane-covered breast implants.O Sepai et al.Toxicology letters, 77(1-3), 371-378 (1995-05-01) Biological monitoring of TDI-derived amines in polyurethane foam production.Shaun Austin Occupational medicine (Oxford, England), 57(6), 444-448 (2007-08-31) Syrian hamster embryo (SHE) cell transformation assay with conditioned media (without X-ray irradiated feeder layer) using 2,4-diaminotoluene, 2,6-diaminotoluene and chloral hydrate.Kamala Pant et al.Mutation research, 654(2), 108-113 (2008-07-09) Air exposure assessment of TDI and biological monitoring of TDA in urine in workers in polyurethane foam industry.Tom Geens et al.Occupational and environmental medicine, 69(2), 93-98 (2011-07-05) Mutagenic carcinogens and noncarcinogens in transgenic mice.P Günzel et al.Environmental health perspectives, 105(2), 163-163 (1997-02-01) Cell proliferation as a determining factor for the carcinogenicity of chemicals: studies with mutagenic carcinogens and mutagenic noncarcinogens.M L Cunningham et al.Toxicology letters, 82-83, 9-14 (1995-12-01) JaCVAM-organized international validation study of the in vivo rodent alkaline comet assay for the detection of genotoxic carcinogens: I. Summary of pre-validation study results.Yoshifumi Uno et al.Mutation research. Genetic toxicology and environmental mutagenesis, 786-788, 3-13 (2015-07-28) Improvement in the GC-MS method for determining urinary toluene-diamine and its application to the biological monitoring of workers exposed to toluene-diisocyanate.Tadashi Sakai et al.International archives of occupational and environmental health, 78(6), 459-466 (2005-05-27) Differential in vivo mutagenicity of the carcinogen/non-carcinogen pair 2,4- and 2,6-diaminotoluene.J J Hayward et al.Carcinogenesis, 16(10), 2429-2433 (1995-10-01) Genotoxic and non-genotoxic activities of 2,4- and 2,6-diaminotoluene, as evaluated in Fischer-344 rat liver.M Taningher et al.Toxicology, 99(1-2), 1-10 (1995-05-05) Biomarkers in hydrolysed urine, plasma and erythrocytes among workers exposed to thermal degradation products from toluene diisocyanate foam.P Lind et al.The Analyst, 122(1), 51-56 (1997-01-01) Biological monitoring as a valid tool to assess occupational exposure to mixtures of 2,4-:2,6-toluene diisocyanate.G De Palma et al.La Medicina del lavoro, 103(5), 361-371 (2012-10-20) Evaluation of the micronucleus test in vitro using Chinese hamster cells: results of four chemicals weakly positive in the in vivo micronucleus test.B M Miller et al.Environmental and molecular mutagenesis, 26(3), 240-247 (1995-01-01) Induction of LacZ mutations in Muta Mouse can distinguish carcinogenic from non-carcinogenic analogues of diaminotoluenes and nitronaphthalenes.David Kirkland et al.Mutation research, 608(1), 88-96 (2006-06-27) Risk evaluation of occupational exposure to methylene dianiline and toluene diamine in polyurethane foam.T A Lewandowski et al.Human & experimental toxicology, 24(12), 655-662 (2006-01-18) Diaminotoluenes induce intrachromosomal recombination and free radicals in Saccharomyces cerevisiae.R J Brennan et al.Mutation research, 381(2), 251-258 (1998-01-22) LC-MS determination of urinary toluenediamine in workers exposed to toluenediisocyanate.Tadashi Sakai et al.Toxicology letters, 134(1-3), 259-264 (2002-08-23) Exposure to 2,4- and 2,6-toluene diisocyanate (TDI) during production of flexible foam: determination of airborne TDI and urinary 2,4- and 2,6-toluenediamine (TDA).K Kääriä et al.The Analyst, 126(7), 1025-1031 (2001-08-02) Distinction of mutagenic carcinogens from a mutagenic noncarcinogen in the big blue transgenic mouse.M L Cunningham et al.Environmental health perspectives, 104 Suppl 3, 683-686 (1996-05-01) Hemoglobin and DNA adduct formation in Fischer-344 rats exposed to 2,4- and 2,6-toluene diamine.P M Wilson et al.Archives of toxicology, 70(10), 591-598 (1996-01-01) Integration of in vivo genotoxicity and short-term carcinogenicity assays using F344 gpt delta transgenic rats: in vivo mutagenicity of 2,4-diaminotoluene and 2,6-diaminotoluene structural isomers.Naomi Toyoda-Hokaiwado et al.Toxicological sciences : an official journal of the Society of Toxicology, 114(1), 71-78 (2009-12-23) Development of a repeated-dose liver micronucleus assay using adult rats (II): further investigation of 1,2-dimethylhydrazine and 2,6-diaminotoluene.Hironao Takasawa et al.Mutation research, 751(1), 12-18 (2012-11-06) Air and biological monitoring of toluene diisocyanate in a flexible foam plant.H Tinnerberg et al.American Industrial Hygiene Association journal, 58(3), 229-235 (1997-03-01) Interaction with the aromatic hydrocarbon receptor, CYP1A induction, and mutagenicity of a series of diaminotoluenes: implications for their carcinogenicity.Y L Cheung et al.Toxicology and applied pharmacology, 139(1), 203-211 (1996-07-01) [Assessment of the emission of volatile organic compounds from polyurethane foams].Irena Pecka et al.Roczniki Panstwowego Zakladu Higieny, 55(2), 181-185 (2004-10-21) Toxicokinetics of 2,4- and 2,6-toluenediamine in hydrolysed urine and plasma after occupational exposure to 2,4- and 2,6- toluene diisocyanate.P Lind et al.Occupational and environmental medicine, 53(2), 94-99 (1996-02-01)

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