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L-Threose | CAS:95-44-3
L-Threose
  • Name:L-Threose
  • CAS:95-44-3
  • Synonyms:L-Threofuranose; (2R,3S)-2,3,4-Trihydroxybutanal
  • Molecular Formula:C4H8O4
  • Molecular Weight:120.10
  • EINESC:202-419-6

Description

Properties

Melting point 162-163 ºC**
Density 1.410±0.06 g/cm3 (20 º

Safety

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SDS

Source SDS/MSDS Samples
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Synthetic Route
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Articles
Peer-Reviewed Papers
Structure-activity relationships of flavanones, flavanone glycosides, and flavones in anti-degranulation activity in rat basophilic leukemia RBL-2H3 cells.Toshiro Noshita et al.Journal of natural medicines, 72(2), 551-556 (2018-01-20) Galangin and Pinocembrin from Propolis Ameliorate Insulin Resistance in HepG2 Cells via Regulating Akt/mTOR Signaling.Yinkang Liu et al.Evidence-based complementary and alternative medicine : eCAM, 2018, 7971842-7971842 (2018-11-14) Pinocembrin attenuates allergic airway inflammation via inhibition of NF-κB pathway in mice.Xiaoyan Gu et al.International immunopharmacology, 53, 90-95 (2017-10-22) Effectiveness of Different Analytical Methods for the Characterization of Propolis: A Case of Study in Northern Italy.Radmila Pavlovic et al.Molecules (Basel, Switzerland), 25(3) (2020-01-26) Building a minimal and generalizable model of transcription factor-based biosensors: Showcasing flavonoids.Heykel Trabelsi et al.Biotechnology and bioengineering, 115(9), 2292-2304 (2018-05-08) Metabolic engineering of Saccharomyces cerevisiae for de novo production of dihydrochalcones with known antioxidant, antidiabetic, and sweet tasting properties.Michael Eichenberger et al.Metabolic engineering, 39, 80-89 (2016-11-05) Anti-staphylococcal activity of C-methyl flavanones from propolis of Australian stingless bees (Tetragonula carbonaria) and fruit resins of Corymbia torelliana (Myrtaceae).C F Massaro et al.Fitoterapia, 95, 247-257 (2014-04-08) In Vitro Interactions of Moroccan Propolis Phytochemical's on Human Tumor Cell Lines and Anti-Inflammatory Properties.Soraia I Falcão et al.Biomolecules, 9(8) (2019-08-01) Antiviral activity of pinocembrin against Zika virus replication.Jia Le Lee et al.Antiviral research, 167, 13-24 (2019-04-09) Towards better quality criteria of European honeydew honey: Phenolic profile and antioxidant capacity.Vesna Vasić et al.Food chemistry, 274, 629-641 (2018-10-31) Capillary electrophoresis as an alternative to HPLC for determination of honey flavonoidsDelgado.C, et al. Chromatographia, 38(1-2), 71-78 (1994) Comparative evaluation of maceration, microwave and ultrasonic-assisted extraction of phenolic compounds from propolis.Mircea Oroian et al.Journal of food science and technology, 57(1), 70-78 (2020-01-25) Quantitative and Discriminative Evaluation of Contents of Phenolic and Flavonoid and Antioxidant Competence for Chinese Honeys from Different Botanical Origins.Shi Shen et al.Molecules (Basel, Switzerland), 23(5) (2018-05-09) Pinocembrin protects SH-SY5Y cells against MPP+-induced neurotoxicity through the mitochondrial apoptotic pathway.Yumin Wang et al.Journal of molecular neuroscience : MN, 53(4), 537-545 (2014-01-08) Discrimination of geographical origins of Chinese acacia honey using complex 13C/12C, oligosaccharides and polyphenols.Seng She et al.Food chemistry, 272, 580-585 (2018-10-13) UHPLC-HESI-OT-MS-MS Biomolecules Profiling, Antioxidant and Antibacterial Activity of the "Orange-Yellow Resin" from Zuccagnia punctata Cav.Jessica Gómez et al.Antioxidants (Basel, Switzerland), 9(2) (2020-02-07) Pinocembrin attenuates lipopolysaccharide-induced inflammatory responses in Labeo rohita macrophages via the suppression of the NF-κB signalling pathway.Sib Sankar Giri et al.Fish & shellfish immunology, 56, 459-466 (2016-08-06) Non-Linear Quantitative Structure⁻Activity Relationships Modelling, Mechanistic Study and In-Silico Design of Flavonoids as Potent Antioxidants.Petar Žuvela et al.International journal of molecular sciences, 20(9) (2019-05-15) Chitosan-propolis nanoparticle formulation demonstrates anti-bacterial activity against Enterococcus faecalis biofilms.Teik Hwa Ong et al.PloS one, 12(3), e0174888-e0174888 (2017-04-01) Propolis can potentialise the anti-adhesion activity of proanthocyanidins on uropathogenic Escherichia coli in the prevention of recurrent urinary tract infections.Jean-Philippe Lavigne et al.BMC research notes, 4, 522-522 (2011-12-01) Antioxidant Activity and Phenolic Profile of Selected Organic and Conventional Honeys from Poland.Michał Halagarda et al.Antioxidants (Basel, Switzerland), 9(1) (2020-01-18) Comparison between In Vitro Antiviral Effect of Mexican Propolis and Three Commercial Flavonoids against Canine Distemper Virus.María de Jesús González-Búrquez et al.Evidence-based complementary and alternative medicine : eCAM, 2018, 7092416-7092416 (2018-09-04) Development and characterization of microencapsules containing spray dried powder obtained from Brazilian brown, green and red propolis.Julianna Karla Santana Andrade et al.Food research international (Ottawa, Ont.), 109, 278-287 (2018-05-29) Propolis Extracted from the Stingless Bee Trigona sirindhornae Inhibited S. mutans Activity In Vitro.Kusumawadee Utispan et al.Oral health & preventive dentistry, 15(3), 279-284 (2017-07-05) Evaluation of bioactive compounds potential and antioxidant activity of brown, green and red propolis from Brazilian northeast region.Julianna Karla Santana Andrade et al.Food research international (Ottawa, Ont.), 101, 129-138 (2017-09-25) Soumaya Touzani et al.BioMed research international, 2019, 4836378-4836378 (2020-01-10)Propolis is a resin that honeybees produce by mixing saliva and beeswax with exudate gathered from botanical sources. The present in vitro study investigated the potential use of propolis as a multitarget therapeutic product and the physicochemical properties, chemical composition... Two CYP82D Enzymes Function as Flavone Hydroxylases in the Biosynthesis of Root-Specific 4'-Deoxyflavones in Scutellaria baicalensis.Qing Zhao et al.Molecular plant, 11(1), 135-148 (2017-08-27) Separation and isolation of major polyphenols from maritime pine (Pinus pinaster) knots by two-step centrifugal partition chromatography monitored by LC-MS and NMR spectroscopy.Julien Gabaston et al.Journal of separation science, 43(6), 1080-1088 (2020-01-24) Biological Evaluation and Docking Analysis of Potent BACE1 Inhibitors from Boesenbergia rotunda.Kumju Youn et al.Nutrients, 11(3) (2019-03-22) Propolis Extract as Antioxidant to Improve Oxidative Stability of Fresh Patties during Refrigerated Storage.Rey David Vargas-Sánchez et al.Foods (Basel, Switzerland), 8(12) (2019-11-28) Beyond the Biological Effect of a Chemically Characterized Poplar Propolis: Antibacterial and Antiviral Activity and Comparison with Flurbiprofen in Cytokines Release by LPS-Stimulated Human Mononuclear Cells.Paolo Governa et al.Biomedicines, 7(4) (2019-09-25) Antiproliferative Activity of Chemically Characterized Propolis from Turkey and Its Mechanisms of Action.Başak Aru et al.Chemistry & biodiversity, 16(7), e1900189-e1900189 (2019-06-22) Targeted and Untargeted Metabolomics as an Enhanced Tool for the Detection of Pomegranate Juice Adulteration.Marilena E Dasenaki et al.Foods (Basel, Switzerland), 8(6) (2019-06-19) Effect of Alpinia katsumadai Hayata on House Dust Mite-Induced Atopic Dermatitis in NC/Nga Mice.Hye-Sun Lim et al.Evidence-based complementary and alternative medicine : eCAM, 2012, 705167-705167 (2012-10-20) Flavonoids Distinctly Stabilize Lymph Endothelial- or Blood Endothelial Disintegration Induced by Colon Cancer Spheroids SW620.Julia Berenda et al.Molecules (Basel, Switzerland), 25(9) (2020-05-06) Transcriptome-enabled discovery and functional characterization of enzymes related to (2S)-pinocembrin biosynthesis from Ornithogalum caudatum and their application for metabolic engineering.Lei Guo et al.Microbial cell factories, 15, 27-27 (2016-02-06) Antimicrobial activity and rutin identification of honey produced by the stingless bee Melipona compressipes manaosensis and commercial honey.Renah Boanerges de Queiroz Pimentel et al.BMC complementary and alternative medicine, 13, 151-151 (2013-07-03) The Anti-Campylobacter Activity and Mechanisms of Pinocembrin Action.Anja Klančnik et al.Microorganisms, 7(12) (2019-12-15) Kaempferide Enhances Chemosensitivity of Human Lung Adenocarcinoma A549 Cells Mediated by the Decrease in Phosphorylation of Akt and Claudin-2 Expression.Hiroaki Eguchi et al.Nutrients, 12(4) (2020-04-29) Foliar Essential Oil Glands of Eucalyptus Subgenus Eucalyptus (Myrtaceae) Are a Rich Source of Flavonoids and Related Non-Volatile Constituents.Jason Q D Goodger et al.PloS one, 11(3), e0151432-e0151432 (2016-03-16) A comparative study between Chinese propolis and Brazilian green propolis: metabolite profile and bioactivity.Min Yuan et al.Food & function, 11(3), 2368-2379 (2020-03-05) Fatty acid and phenolic profiles of almond grown in Serbia.Slavica D Čolić et al.Food chemistry, 234, 455-463 (2017-05-30) Phenolic profile, antioxidant activity and enzyme inhibitory activities of extracts from aromatic plants used in Mediterranean diet.Sandra Gonçalves et al.Journal of food science and technology, 54(1), 219-227 (2017-03-01) NMR assessment of European acacia honey origin and composition of EU-blend based on geographical floral markers.Elisabetta Schievano et al.Food chemistry, 288, 96-101 (2019-03-25) Development of supercritical CO2 extraction of bioactive phytochemicals from black poplar (Populus nigra L.) buds followed by GC-MS and UHPLC-DAD-QqTOF-MS.Piotr M Kuś et al.Journal of pharmaceutical and biomedical analysis, 158, 15-27 (2018-06-01) Determination of Phenolic Compounds in Three Edible Ripening Stages of Yellow Guava (Psidium cattleianum Sabine) after Acidic Hydrolysis by LC-MS/MS.Mayara Schulz et al.Plant foods for human nutrition (Dordrecht, Netherlands), 75(1), 110-115 (2020-01-08) Pinocembrin: a novel natural compound with versatile pharmacological and biological activitiesRasul A, et al. BioMed Research International, 2013(1-2), 71-78 (2013) Inhibitory effects of flavonoids on P-glycoprotein in vitro and in vivo: Food/herb-drug interactions and structure-activity relationships.Jie Bai et al.Toxicology and applied pharmacology, 369, 49-59 (2019-02-23) Phloroglucinols from anti-microbial deposit-resins of Australian stingless bees (Tetragonula carbonaria).C Flavia Massaro et al.Phytotherapy research : PTR, 29(1), 48-58 (2014-09-19) TLC determination of some flavanones in the buds of different genus Populus species and hybrids.Loretta Pobłocka-Olech et al.Acta pharmaceutica (Zagreb, Croatia), 68(2), 199-210 (2018-04-28) Drug interaction study of flavonoids toward OATP1B1 and their 3D structure activity relationship analysis for predicting hepatoprotective effects.Xiaoqing Fan et al.Toxicology, 437, 152445-152445 (2020-04-08) A New Type of Anatolian Propolis: Evaluation of Its Chemical Composition, Activity Profile and Botanical Origin.Hacer Tugba Degirmencioglu et al.Chemistry & biodiversity, 16(12), e1900492-e1900492 (2019-10-24) Evaluation of phenolic profile, enzyme inhibitory and antimicrobial activities of Nigella sativa L. seed extracts.Anela Topcagic et al.Bosnian journal of basic medical sciences, 17(4), 286-294 (2017-06-08) Pinocembrin protects against β-amyloid-induced toxicity in neurons through inhibiting receptor for advanced glycation end products (RAGE)-independent signaling pathways and regulating mitochondrion-mediated apoptosis.Rui Liu et al.BMC medicine, 10, 105-105 (2012-09-20) Photoprotective and Antigenotoxic Effects of the Flavonoids Apigenin, Naringenin and Pinocembrin.Adriana García Forero et al.Photochemistry and photobiology, 95(4), 1010-1018 (2019-01-13) Pinocembrin⁻Lecithin Complex: Characterization, Solubilization, and Antioxidant Activities.Xu Yang et al.Biomolecules, 8(2) (2018-06-21) Extraction of Phenolic Compounds from Tabernaemontana catharinensis Leaves and Their Effect on Oxidative Stress Markers in Diabetic Rats.Rafael Sari et al.Molecules (Basel, Switzerland), 25(10) (2020-05-28) Chemical and botanical characterization of Chilean propolis and biological activity on cariogenic bacteria Streptococcus mutans and Streptococcus sobrinus.Leticia Barrientos et al.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 44(2), 577-585 (2013-12-03) A New Propolis Type from Changbai Mountains in North-east China: Chemical Composition, Botanical Origin and Biological Activity.Xiasen Jiang et al.Molecules (Basel, Switzerland), 24(7) (2019-04-11) Effect of Natural Phenolics on Pharmacokinetic Modulation of Bedaquiline in Rat to Assess the Likelihood of Potential Food-Drug Interaction.Pankul Kotwal et al.Journal of agricultural and food chemistry, 68(5), 1257-1265 (2020-01-14) Pre-Clinical Pharmacokinetic and Pharmacodynamic Characterization of Selected Chiral Flavonoids: Pinocembrin and Pinostrobin.Casey L Sayre et al.Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 18(4), 368-395 (2015-12-03) The Anti-Staphylococcal Potential of Ethanolic Polish Propolis Extracts.Katarzyna Grecka et al.Molecules (Basel, Switzerland), 24(9) (2019-05-07) Chemical Composition and Anti-Inflammatory Effect of Ethanolic Extract of Brazilian Green Propolis on Activated J774A.1 Macrophages.Ewelina Szliszka et al.Evidence-based complementary and alternative medicine : eCAM, 2013, 976415-976415 (2013-07-11) Evaluation of cellular antioxidant components of honeys using UPLC-MS/MS and HPLC-FLD based on the quantitative composition-activity relationship.Shi Shen et al.Food chemistry, 293, 169-177 (2019-06-04) Pre-Clinical Pharmacokinetic and Pharmacodynamic Characterization of Selected Chiral Flavonoids: Pinocembrin and Pinostrobin.Casey L Sayre et al.Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 18(4), 368-395 (2015-12-03) Pinocembrin, a novel histidine decarboxylase inhibitor with anti-allergic potential in in vitro.Hamza Hanieh et al.European journal of pharmacology, 814, 178-186 (2017-08-20) Validated method for estimation of total flavonoids in Romanian propolisMarghitas, et al. Bulletin UASVM Food Science and Technology, 63, 64-64 (2007) Phytochemical fingerprints of lime honey collected in serbia.Uroš Gašić et al.Journal of AOAC International, 97(5), 1259-1267 (2015-04-24) Activation of the cannabinoid receptor 1 by ACEA suppresses senescence in human primary chondrocytes through sirt1 activation.Dawei Zhang et al.Experimental biology and medicine (Maywood, N.J.), 243(5), 437-443 (2018-02-16) The new buzz: Investigating the antimicrobial interactions between bioactive compounds found in South African propolis.K Kharsany et al.Journal of ethnopharmacology, 238, 111867-111867 (2019-04-13) Pinocembrin protects endothelial cells from oxidized LDL-induced injury.Qiang Su et al.Cytokine, 111, 475-480 (2018-06-20) Inhibition of Tyrosine-Phosphorylated STAT3 in Human Breast and Lung Cancer Cells by Manuka Honey is Mediated by Selective Antagonism of the IL-6 Receptor.Priyanka Aryappalli et al.International journal of molecular sciences, 20(18) (2019-09-08)
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