Melting point	63-67 ºC
Water Solubility	slightly soluble
Boiling point	227 ºC
Flash point	61 ºC

Symbol(GHS)	T;N
Hazard Codes	R24/25;R34;R51/53
SDS/MSDS	S26;S36/37/39;S45;S61

Source	SDS/MSDS Samples
没有数据	没有数据

Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

Non-animal photosafety screening for complex cosmetic ingredients with photochemical and photobiochemical assessment tools.Hayato Nishida et al.Regulatory toxicology and pharmacology : RTP, 72(3), 578-585 (2015-06-07) Mechanism for 6-methylcoumarin photoallergenicity.S Kato et al.Toxicology and applied pharmacology, 81(2), 295-301 (1985-11-01) Perfume dermatitis.W G Larsen Journal of the American Academy of Dermatology, 12(1 Pt 1), 1-9 (1985-01-01) Complete reduction of 2H-pyran-2-one moiety of coumarin and 6-methyl coumarin by Colletotrichum capsici.Gadepalli Narasimha Krishna Kumari et al.Zeitschrift fur Naturforschung. C, Journal of biosciences, 59(5-6), 405-407 (2008-11-13) Experimental photoallergic contact dermatitis: a mouse model.H C Maguire et al.The Journal of investigative dermatology, 79(3), 147-152 (1982-09-01) Use of the occlusive patch to evaluate the photosensitive properties of chemicals in guinea-pigs.E V Buehler et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 23(7), 689-694 (1985-07-01) Photochemical formation of singlet molecular oxygen ((1)O2) in illuminated 6-methylcoumarin solutions.S K Allen et al.Biochemical and biophysical research communications, 235(3), 615-618 (1997-06-27) Comparison of the hepatic effects of coumarin, 3,4-dimethylcoumarin, dihydrocoumarin and 6-methylcoumarin in the rat.B G Lake et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 32(8), 743-751 (1994-08-01) The identification of photoallergic potential in the local lymph node assay.E W Scholes et al.Photodermatology, photoimmunology & photomedicine, 8(6), 249-254 (1991-12-01) Fourier transform-infrared and Raman spectra, ab initio calculations and assignments for 6-methyl-4-bromomethylcoumarin.Veenasangeeta Sortur et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 64(2), 301-307 (2006-04-29) Use of UVB and UVA to induce and elicit contact photoallergy in the mouse.G F Gerberick et al.Photodermatology, photoimmunology & photomedicine, 7(1), 13-19 (1990-02-01) Photoallergic contact dermatitis. Results of photopatch testing in New York, 1985 to 1990.V A DeLeo et al.Archives of dermatology, 128(11), 1513-1518 (1992-11-01) In vitro phototoxicity test using artificial skin with melanocytes.Jong Hee Lee et al.Photodermatology, photoimmunology & photomedicine, 23(2-3), 73-80 (2007-05-26) Supramolecular photocatalysis by confinement--photodimerization of coumarins within cucurbit[8]urils.Barry C Pemberton et al.Chemical communications (Cambridge, England), 46(2), 225-227 (2009-12-22) Aquatic toxicity assessment of the additive 6-methylcoumarine using four experimental systems.A Jos et al.Archives of environmental contamination and toxicology, 56(1), 52-59 (2008-04-09) Phosphorylation of histone H2AX is a powerful tool for detecting chemical photogenotoxicity.Tatsushi Toyooka et al.The Journal of investigative dermatology, 131(6), 1313-1321 (2011-03-04) [New data on photoallergy].D Kleniewska et al.Przeglad dermatologiczny, 70(2), 221-224 (1983-03-01) Photoallergic contact sensitization to 6-methylcoumarin in poikiloderma of Civatte.Vasanop Vachiramon et al.Dermatitis : contact, atopic, occupational, drug, 16(3), 136-138 (2005-10-26) Development of a highly sensitive in vitro phototoxicity assay using the SkinEthic reconstructed human epidermis.F X Bernard et al.Cell biology and toxicology, 16(6), 391-400 (2001-03-20) Vibrational and ab initio studies of 3-acetyl-6-bromocoumarin and 3-acetyl-6-methylcoumarin.Anuradha Ramoji et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 77(5), 1039-1047 (2010-09-22) Stable isotope labeling method for the investigation of protein haptenation by electrophilic skin sensitizers.Erika Parkinson et al.Toxicological sciences : an official journal of the Society of Toxicology, 142(1), 239-249 (2014-08-26) Infrared study of 6-methylcoumarin in binary solvent mixtures.Feiying Zhang et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 71(2), 710-713 (2008-03-25) Simultaneous determination of 6-methylcoumarin and 7-methoxycoumarin in cosmetics using three-dimensional excitation-emission matrix fluorescence coupled with second-order calibration methods.Jin-Fang Nie et al.Talanta, 75(5), 1260-1269 (2008-07-01) The guinea pig as a model for predicting photoallergic contact dermatitis.W P Jordan Contact dermatitis, 8(2), 109-116 (1982-03-01) Supramolecular photocatalysis: insights into cucurbit[8]uril catalyzed photodimerization of 6-methylcoumarin.Barry C Pemberton et al.Chemical communications (Cambridge, England), 47(22), 6323-6325 (2011-05-05) Induction of keratinocyte apoptosis by photosensitizing chemicals plus UVA.Masako Kurita et al.Journal of dermatological science, 45(2), 105-112 (2006-12-05) Development of an in vitro photosensitization assay using human monocyte-derived cells.Masatoshi Hoya et al.Toxicology in vitro : an international journal published in association with BIBRA, 23(5), 911-918 (2009-04-11) A kinetic study of the main guaco metabolites using syrup formulation and the identification of an alternative route of coumarin metabolism in humans.João Cleverson Gasparetto et al.PloS one, 10(3), e0118922-e0118922 (2015-03-11)

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