Water Solubility	miscible
Boiling point	188-189 ºC
Flash point	80 ºC
Density	1.063
Refractive index	1.433-1.435

SDS/MSDS	S24/25

Source	SDS/MSDS Samples
没有数据	没有数据

Synthetic Route

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Articles

Peer-Reviewed Papers

Identification and quantification of methyl nicotinate in rice (Oryza sativa L.) by gas chromatography-mass spectrometryRB Muralidhara, et al. Food Chemistry, 105(2), 736-741 (2007) Topical antirheumatic agents as hydroxyl radical scavengersBillany MR, et al. International Journal of Pharmaceutics, 124(2), 279-283 (1995) A facile synthesis of ? -sesbanine via γ-addition of ketene silyl acetal with quaternized methyl nicotinateWada M, et al. Tetrahedron Letters, 26(27), 3267-3270 (1985) Determination of the in vivo bioavailability of iontophoretically delivered diclofenac using a methyl nicotinate skin inflammation assay.Renzo Lambrecht et al.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 12(3), 211-216 (2006-07-11) Evaluation of simultaneous permeation and metabolism of methyl nicotinate in human, snake, and shed snake skin.Tanasait Ngawhirunpat et al.Pharmaceutical development and technology, 13(1), 75-83 (2008-02-27) Comparison of instruments for investigation of microcirculatory blood flow and red blood cell concentration.Jim O'Doherty et al.Journal of biomedical optics, 14(3), 034025-034025 (2009-07-02) In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities.Giorgio Ottaviani et al.Journal of medicinal chemistry, 50(4), 742-748 (2007-02-16) In vitro cutaneous application of ISCOMs on human skin enhances delivery of hydrophobic model compounds through the stratum corneum.Henriette Baun Madsen et al.The AAPS journal, 11(4), 728-739 (2009-10-29) Establishing a minimal erythema concentration of methyl nicotinate for optimum evaluation of anti-inflammatories.L C Jumbelic et al.Skin pharmacology and physiology, 19(3), 147-152 (2006-04-14) A non-invasive method for the in vivo determination of skin antioxidant capacity (IAC-S).Paola Ziosi et al.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 12(4), 303-308 (2006-10-10) The topical niacin sensitivity test: an inter- and intra-rater reliability study in healthy controls.Melissa Kerr et al.Prostaglandins, leukotrienes, and essential fatty acids, 79(1-2), 15-19 (2008-07-29) Effects of neonatal treatment with the TRPV1 agonist, capsaicin, on adult rat brain and behaviour.Penny N Newson et al.Behavioural brain research, 272, 55-65 (2014-07-01) Synthesis of 3, 5-diacyl-4-phenyl-1, 4-dihydropyridinesBennasar M-L, et al. Tetrahedron Letters, 39(50), 9275-9278 (1998) In-vitro and in-vivo evaluation of oligoethylene esters as dermal prodrugs of 18beta-glycyrrhetic acid.Carmelo Puglia et al.The Journal of pharmacy and pharmacology, 58(3), 311-319 (2006-03-16) Effect of charge and lipid concentration on in-vivo percutaneous absorption of methyl nicotinate from liposomal vesicles.Carmelo Puglia et al.The Journal of pharmacy and pharmacology, 57(9), 1169-1176 (2005-08-18) Pattern recognition analysis for classification of hypertensive model rats and diurnal variation using 1H-NMR spectroscopy of urine.Masako Fujiwara et al.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 21(11), 1259-1262 (2005-12-02) Time of erythema onset after application of methyl nicotinate ointments as response parameter: influence of penetration kinetics and enhancing agents.Y Remane et al.Skin pharmacology and physiology, 19(6), 303-310 (2006-08-26) Effects of lipid nanocarriers on the performance of topical vehicles in vivo.Mojgan Moddaresi et al.Journal of cosmetic dermatology, 8(2), 136-143 (2009-06-17) A general synthesis of 5-arylnicotinatesThompson WJ and Gaudino J The Journal of Organic Chemistry, 49(26), 5237-5243 (1984) Excess substrate is a spectator ligand in a rhodium-catalyzed asymmetric [2 + 2 + 2] cycloaddition of alkenyl isocyanates with tolanes.Mark Emil Oinen et al.Organic letters, 11(21), 4934-4937 (2009-10-07) Comfrey root: from tradition to modern clinical trials.Christiane Staiger Wiener medizinische Wochenschrift (1946), 163(3-4), 58-64 (2012-12-12) Detection and visualization of intracutaneous allergic type-specific elements using long-wavelength near-infrared hyperspectral imaging.Ken Nishino et al.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 19(1), e157-e166 (2012-06-08) cIEF for rapid pKa determination of small molecules: a proof of concept.Stéphanie Romand et al.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 63, 14-21 (2014-07-06) Percutaneous penetration of methyl nicotinate from ointments using the laser Doppler technique: bioequivalence and enhancer effects.Yvonne Remane et al.Journal of pharmacokinetics and pharmacodynamics, 33(6), 719-735 (2006-09-29) Helical and zigzag coordination polymeric chains derived from di-3-pyridyl ketone and silver (I) saltsChen X-D and Mak Thomas CW Journal of Molecular Structure, 743(1-3), 1-6 (2005) A new coordination mode of 6-methylnicotinic acid in trans-tetraaquabis(6-methylpyridine-3-carboxylato-kappaO)cobalt(II) tetrahydrate.Boris-Marko Kukovec et al.Acta crystallographica. Section C, Crystal structure communications, 63(Pt 12), m615-m617 (2007-12-07) The scent of Mycobacterium tuberculosis--part II breath.Mona Syhre et al.Tuberculosis (Edinburgh, Scotland), 89(4), 263-266 (2009-06-02) Perturbation of solute transport at a liquid-liquid interface by polyethylene glycol (PEG): implications for PEG-induced biomembrane fusion.Richard H Guy et al.Physical chemistry chemical physics : PCCP, 13(12), 5346-5352 (2011-02-03) Niacin sensitivity and the arachidonic acid pathway in schizophrenia.Erik Messamore et al.Schizophrenia research, 122(1-3), 248-256 (2010-04-27) Transfer of the experimental methodology described in the FDA guidance for corticosteroid bioequivalence testing to pharmacodynamic effects caused by nicotinates.Yvonne Remane et al.Journal of cosmetic dermatology, 5(4), 289-293 (2007-08-25) Anti-inflammatory activity in skin by biomimetic of Evodia rutaecarpa extract from traditional Chinese medicine.Daniel B Yarosh et al.Journal of dermatological science, 42(1), 13-21 (2006-01-21) Stability of methylnicotinate in aqueous solution as utilized in the'niacin patch test'Ross BM and Katzman M BMC Research Notes, 1(1), 89-89 (2008) Influence of skin colour on the detection of cutaneous erythema and tanning phenomena using reflectance spectrophotometry.Julie Latreille et al.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 13(3), 236-241 (2007-07-06) Parallel artificial membrane permeability assay: a new membrane for the fast prediction of passive human skin permeability.Giorgio Ottaviani et al.Journal of medicinal chemistry, 49(13), 3948-3954 (2006-06-23) Honeybees Apis mellifera can detect the scent of Mycobacterium tuberculosis.David M Suckling et al.Tuberculosis (Edinburgh, Scotland), 91(4), 327-328 (2011-05-07) Cannabinoids influence lipid-arachidonic acid pathways in schizophrenia.Stefan Smesny et al.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 32(10), 2067-2073 (2007-02-23) The scent of Mycobacterium tuberculosis.Mona Syhre et al.Tuberculosis (Edinburgh, Scotland), 88(4), 317-323 (2008-02-26) Influence of the Supramolecular Micro-Assembly of Multiple Emulsions on their Biopharmaceutical Features and In vivo Therapeutic Response.Felisa Cilurzo et al.Current drug targets, 16(14), 1612-1622 (2015-11-26)

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