4-Pyridinecarboxaldehyde N-oxide | CAS:7216-42-4
            
            4-Pyridinecarboxaldehyde N-oxide
            - Name:4-Pyridinecarboxaldehyde N-oxide
 - CAS:7216-42-4
 - Synonyms:
 - Molecular Formula:C6H5NO2
 - Molecular Weight:123.11
 - EINESC:230-602-0
 
Description
Properties
| Melting point | 150-152 ºC | 
|---|
Safety
| Symbol(GHS) | Xi | 
|---|---|
| Hazard Codes | R36/37/38 | 
| SDS/MSDS | S26;S36 | 
SDS
| Source | SDS/MSDS Samples | 
|---|---|
| Sigma-Aldrich | View & Download | 
Synthetic Route
                | Name | CAS | 
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More
            Articles
                Peer-Reviewed Papers
                
                                        A kinetic study of the photodynamic effect on tryptophan methyl ester and tryptophan octyl ester in DOPC vesicles.Ariana Posadaz et al.Photochemistry and photobiology, 86(1), 96-103 (2009-11-26)
                                        Sumatriptan normalizes the migraine attack-related increase in brain serotonin synthesis.Y Sakai et al.Neurology, 70(6), 431-439 (2008-02-06)
                                        Mouse model for allogeneic immune reaction against fetus recapitulates human pre-eclampsia.Haruki Nishizawa et al.The journal of obstetrics and gynaecology research, 34(1), 1-6 (2008-01-30)
                                        Inhibitor of indoleamine-2,3-dioxygenase 1-methyl-D-tryptophan can stimulate the growth of immunogenic tumors.E D Vasil'eva et al.Bulletin of experimental biology and medicine, 149(5), 625-627 (2010-12-18)
                                        Indoleamine 2,3-dioxygenase as a new target for malignant glioma therapy. Laboratory investigation.Takeshi Miyazaki et al.Journal of neurosurgery, 111(2), 230-237 (2009-02-10)
                                        Imaging correlates of differential expression of indoleamine 2,3-dioxygenase in human brain tumors.Carlos E A Batista et al.Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging, 11(6), 460-466 (2009-05-13)
                                        Can diffusion tensor imaging (DTI) identify epileptogenic tubers in tuberous sclerosis complex? Correlation with α-[11C]methyl-L-tryptophan ([11C] AMT) positron emission tomography (PET).Vijay Narayan Tiwari et al.Journal of child neurology, 27(5), 598-603 (2011-12-06)
                                        Inhibition of indoleamine 2,3-dioxygenase activity by levo-1-methyl tryptophan blocks gamma interferon-induced Chlamydia trachomatis persistence in human epithelial cells.Joyce A Ibana et al.Infection and immunity, 79(11), 4425-4437 (2011-09-14)
                                        Human plasmacytoid dendritic cells induce CD8⁺ LAG-3⁺ Foxp3⁺ CTLA-4⁺ regulatory T cells that suppress allo-reactive memory T cells.Patrick P C Boor et al.European journal of immunology, 41(6), 1663-1674 (2011-04-07)
                                        Functionalized magnetonanoparticles for MRI diagnosis and localization in epilepsy.Massoud Akhtari et al.Epilepsia, 49(8), 1419-1430 (2008-05-16)
                                        Abnormal brain tryptophan metabolism and clinical correlates in Tourette syndrome.Michael Behen et al.Movement disorders : official journal of the Movement Disorder Society, 22(15), 2256-2262 (2007-08-22)
                                        Indoleamine 2,3-dioxygenase expression promotes renal ischemia-reperfusion injury.Kanishka Mohib et al.American journal of physiology. Renal physiology, 295(1), F226-F234 (2008-05-16)
                                        Cis-diastereoselectivity in pictet-spengler reactions of L-tryptophan and electronic circular dichroism studies.Naghmana Rashid et al.Chirality, 24(10), 789-795 (2012-07-05)
                                        Tumor immune escape mediated by indoleamine 2,3-dioxygenase.Maria Zamanakou et al.Immunology letters, 111(2), 69-75 (2007-07-24)
                                        Mesenchymal stem cells can induce long-term acceptance of solid organ allografts in synergy with low-dose mycophenolate.F C Popp et al.Transplant immunology, 20(1-2), 55-60 (2008-09-03)
                                        1-L-methyltryptophan is a more effective inhibitor of vertebrate IDO2 enzymes than 1-D-methyltryptophan.Hajime J Yuasa et al.Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 157(1), 10-15 (2010-04-20)
                                        Toxicology and pharmacokinetics of 1-methyl-d-tryptophan: absence of toxicity due to saturating absorption.Lee Jia et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 46(1), 203-211 (2007-09-18)
                                        99mTc-DTPA-amino acids conjugate as specific SPECT pharmaceuticals for tumor imaging.Deepa Sinha et al.Chemical biology & drug design, 74(2), 159-164 (2009-07-21)
                                        The preference of tryptophan for membrane interfaces: insights from N-methylation of tryptophans in gramicidin channels.Haiyan Sun et al.The Journal of biological chemistry, 283(32), 22233-22243 (2008-06-14)
                                        Comment on "Reduced cytotoxic function of effector CD8+ T cells is responsible for indoleamine 2,3-dioxygenase-dependent immune suppression".Rikke Baek Sørensen et al.Journal of immunology (Baltimore, Md. : 1950), 183(10), 6040-6040 (2009-11-06)
                                        Preclinical evaluation of HIV eradication strategies in the simian immunodeficiency virus-infected rhesus macaque: a pilot study testing inhibition of indoleamine 2,3-dioxygenase.Richard M Dunham et al.AIDS research and human retroviruses, 29(2), 207-214 (2012-08-29)
                                        Tryptophan hydroxylase(2) gene polymorphisms predict brain serotonin synthesis in the orbitofrontal cortex in humans.L Booij et al.Molecular psychiatry, 17(8), 809-817 (2011-07-13)
                                        Biochemical characteristics and inhibitor selectivity of mouse indoleamine 2,3-dioxygenase-2.Christopher Jonathan Daraius Austin et al.Amino acids, 39(2), 565-578 (2010-02-09)
                                        Regioselective nitration of N(alpha),N(1)-bis(trifluoroacetyl)-L-tryptophan methyl ester: efficient synthesis of 2-nitro and 6-nitro-N-trifluoroacetyl-L-tryptophan methyl ester.Andrew S Osborne et al.Bioorganic & medicinal chemistry letters, 18(21), 5750-5752 (2008-10-15)
                                        Characterization of the kynurenine pathway in NSC-34 cell line: implications for amyotrophic lateral sclerosis.Yiquan Chen et al.Journal of neurochemistry, 118(5), 816-825 (2010-12-25)
                                    
            Remarks
                
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