4-Hydroxybut-2-ynoic acid | CAS:7218-52-2
            
            4-Hydroxybut-2-ynoic acid
            - Name:4-Hydroxybut-2-ynoic acid
 - CAS:7218-52-2
 - Synonyms:
 - Molecular Formula:C4H4O3
 - Molecular Weight:100.07
 - EINESC:
 
Description
Properties
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Safety
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SDS
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Synthetic Route
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More
            Articles
                Peer-Reviewed Papers
                
                                        Protective effects of combined treatment with mild hypothermia and edaravone against cerebral ischemia/reperfusion injury via oxidative stress and Nrf2 pathway regulation.Hang Yu et al.International journal of oncology, 57(2), 500-508 (2020-07-07)
                                        Rosmarinic acid protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurotoxicity in zebrafish embryos.Yue Zhao et al.Toxicology in vitro : an international journal published in association with BIBRA, 65, 104823-104823 (2020-03-10)
                                        Application of Mass Spectrometry Profiling to Establish Brusatol as an Inhibitor of Global Protein Synthesis.Steffan Vartanian et al.Molecular & cellular proteomics : MCP, 15(4), 1220-1231 (2015-12-30)
                                        Brusatol provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity-implications for therapeutic targeting of Nrf2.Adedamola Olayanju et al.Free radical biology & medicine, 78, 202-212 (2014-12-03)
                                        Progressive Rotavirus Infection Downregulates Redox-Sensitive Transcription Factor Nrf2 and Nrf2-Driven Transcription Units.Upayan Patra et al.Oxidative medicine and cellular longevity, 2020, 7289120-7289120 (2020-04-24)
                                        Docosahexaenoic Acid Protects Traumatic Brain Injury by Regulating NOX2 Generation via Nrf2 Signaling Pathway.Wei Zhu et al.Neurochemical research, 45(8), 1839-1850 (2020-07-18)
                                        Mechanism of eukaryotic protein synthesis inhibition by brusatol.W Willingham et al.Biochimica et biophysica acta, 654(2), 169-174 (1981-07-27)
                                        Transcription factors Nrf2 and NF-κB contribute to inflammation and apoptosis induced by intestinal ischemia-reperfusion in mice.Meng Q T, et al. International Journal of Molecular Medicine, 40(6), 1731-1740 (2017)
                                        Application of mass spectrometry profiling to establish brusatol as an inhibitor of global protein synthesis.Vartanian S, et al. Molecular and Cellular Proteomics, 15(4), 1220-1231 (2016)
                                        Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism.Ren V, et al. Proceedings of the National Academy of Sciences of the USA, 108(4), 201014275-201014275 (2011)
                                        Transcription factors Nrf2 and NF-κB contribute to inflammation and apoptosis induced by intestinal ischemia-reperfusion in mice.Qing-Tao Meng et al.International journal of molecular medicine, 40(6), 1731-1740 (2017-10-19)
                                        Upregulation of nuclear factor (erythroid-derived 2)-like 2 protein level in the human colorectal adenocarcinoma cell line DLD-1 by a heterocyclic organobismuth(III) compound: Effect of organobismuth(III) compound on NRF2 signaling.Katsuya Iuchi et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 125, 109928-109928 (2020-02-01)
                                        Hepatic FNDC5 is a potential local protective factor against Non-Alcoholic Fatty Liver.Clémence M Canivet et al.Biochimica et biophysica acta. Molecular basis of disease, 1866(5), 165705-165705 (2020-02-01)
                                    
            Remarks
                
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