没有数据	没有数据

没有数据	没有数据

Source	SDS/MSDS Samples
Sigma-Aldrich	View & Download
TCI	View & Download

Synthetic Route

More

Name	CAS

More

Articles

Peer-Reviewed Papers

Inhibition of endothelial Slit2/Robo1 signaling by thalidomide restrains angiogenesis by blocking the PI3K/Akt pathway.Yinan Li et al.Digestive diseases and sciences, 59(12), 2958-2966 (2014-10-19) Low-dose lenalidomide plus cytarabine induce complete remission that can be predicted by genetic profiling in elderly acute myeloid leukemia patients.G Visani et al.Leukemia, 28(4), 967-970 (2014-01-21) Prenatal exposure to permethrin influences vascular development of fetal brain and adult behavior in mice offspring.Satoshi Imanishi et al.Environmental toxicology, 28(11), 617-629 (2013-10-24) Multiple myeloma: 2014 Update on diagnosis, risk-stratification, and management.S Vincent Rajkumar American journal of hematology, 89(10), 999-1009 (2014-09-17) Treatment for high-risk smoldering myeloma.Sigurdur Y Kristinsson et al.The New England journal of medicine, 369(18), 1762-1763 (2013-11-01) Recent advances on phosphodiesterase 4 inhibitors for the treatment of asthma and chronic obstructive pulmonary disease.Arumugam Kodimuthali et al.Journal of medicinal chemistry, 51(18), 5471-5489 (2008-08-09) [A case in which chromosome 5q deletion syndrome resistant to lenalidomide therapy transformed to refractory anemia with excess blasts].Michiko Yamada et al.Gan to kagaku ryoho. Cancer & chemotherapy, 40(13), 2593-2597 (2013-12-18) Thalidomide ameliorates inflammation and vascular injury but aggravates tubular damage in the irradiated mouse kidney.Marion Scharpfenecker et al.International journal of radiation oncology, biology, physics, 89(3), 599-606 (2014-06-15) Preliminary biological evaluations of new thalidomide analogues for multiple sclerosis application.Christiane Contino-Pépin et al.Bioorganic & medicinal chemistry letters, 19(3), 878-881 (2008-12-24) Lenalidomide-based maintenance therapy reduces TNF receptor 2 on CD4 T cells and enhances immune effector function in acute myeloid leukemia patients.Chindu Govindaraj et al.American journal of hematology, 89(8), 795-802 (2014-04-24) Synthesis, configurational stability and stereochemical biological evaluations of (S)- and (R)-5-hydroxythalidomides.Takeshi Yamamoto et al.Bioorganic & medicinal chemistry letters, 19(14), 3973-3976 (2009-03-20) Pomalidomide is teratogenic in rats and rabbits and can be neurotoxic in humans.Jerome B Zeldis et al.Proceedings of the National Academy of Sciences of the United States of America, 110(50), E4819-E4819 (2013-12-05) Treatment for high-risk smoldering myeloma.Kenji Tsuda et al.The New England journal of medicine, 369(18), 1763-1763 (2013-11-01) Involvement of peripheral TRPV1 channels in the analgesic effects of thalidomide.Tieying Song et al.Neurochemistry international, 85-86, 40-45 (2015-05-02) Thalidomide prolongs survival after experimental musculoskeletal injury, through an effect on mononuclear apoptosis.Konstantinos Panousis et al.The Journal of surgical research, 188(1), 198-205 (2013-12-24) Modeling and simulation to probe the pharmacokinetic disposition of pomalidomide R- and S-enantiomers.Yan Li et al.The Journal of pharmacology and experimental therapeutics, 350(2), 265-272 (2014-05-17) Design, synthesis and antitumor evaluation of novel thalidomide dithiocarbamate and dithioate analogs against Ehrlich ascites carcinoma-induced solid tumor in Swiss albino mice.Magdy A-H Zahran et al.Bioorganic & medicinal chemistry, 16(22), 9708-9718 (2008-10-28) Role of consolidation therapy in transplant eligible multiple myeloma patients.Michele Cavo et al.Seminars in oncology, 40(5), 610-617 (2013-10-19) VTD consolidation, without bisphosphonates, reduces bone resorption and is associated with a very low incidence of skeletal-related events in myeloma patients post ASCT.E Terpos et al.Leukemia, 28(4), 928-934 (2013-09-21) [Spondyloarthritis including psoriatic arthritis].A Krause et al.Deutsche medizinische Wochenschrift (1946), 139(40), 2017-2019 (2014-09-26) Carfilzomib, lenalidomide, and dexamethasone for relapsed multiple myeloma.A Keith Stewart et al.The New England journal of medicine, 372(2), 142-152 (2014-12-09) Bleeding from gastrointestinal tract recurrence of non-seminomatous germ cell tumour testis, showing temporary response to gemcitabine and oxaliplatin chemotherapy.Stephanie K Prince et al.The New Zealand medical journal, 126(1385), 76-80 (2013-11-13) Thalidomide for the treatment of hydroa vacciniforme-like lymphoma: report of four pediatric cases from Peru.Brady E Beltrán et al.American journal of hematology, 89(12), 1160-1161 (2014-09-10) Thalidomide is an inhibitor of angiogenesis.R J D'Amato et al.Proceedings of the National Academy of Sciences of the United States of America, 91(9), 4082-4085 (1994-04-26) Farnesol inhibits tumor growth and enhances the anticancer effects of bortezomib in multiple myeloma xenograft mouse model through the modulation of STAT3 signaling pathway.Jong Hyun Lee et al.Cancer letters, 360(2), 280-293 (2015-02-24) Effects of systemic Thalidomide and intracerebroventricular Etanercept and Infliximab administration in a Streptozotocin induced dementia model in rats.H Kübra Elçioğlu et al.Acta histochemica, 117(2), 176-181 (2015-01-19) How does lenalidomide target the chronic lymphocytic leukemia microenvironment?Arnon P Kater et al.Blood, 124(14), 2184-2189 (2014-08-28) Differentiation of antiinflammatory and antitumorigenic properties of stabilized enantiomers of thalidomide analogs.Vincent Jacques et al.Proceedings of the National Academy of Sciences of the United States of America, 112(12), E1471-E1479 (2015-03-17) Post-transplantation consolidation and maintenance therapy with lenalidomide for Japanese patients with multiple myeloma.Hiroyuki Takamatsu et al.Anticancer research, 33(12), 5681-5685 (2013-12-11) Addition of lenalidomide to rituximab, ifosfamide, carboplatin, etoposide (RICER) in first-relapse/primary refractory diffuse large B-cell lymphoma.Tatyana Feldman et al.British journal of haematology, 166(1), 77-83 (2014-03-26) Angiogenesis inhibitors derived from thalidomide.Tomomi Noguchi et al.Bioorganic & medicinal chemistry letters, 15(24), 5509-5513 (2005-09-27) Development and biological evaluation of C(60) fulleropyrrolidine-thalidomide dyad as a new anti-inflammation agent.Sheng-Tung Huang et al.Bioorganic & medicinal chemistry, 16(18), 8619-8626 (2008-08-30) Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.R Scott Obach et al.Drug metabolism and disposition: the biological fate of chemicals, 36(7), 1385-1405 (2008-04-23) Prurigo nodularis and Hashimoto thyroiditis.Rahul Rishi et al.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 113(6), 673-674 (2014-12-03) Progesterone receptor antagonists with a 3-phenylquinazoline-2,4-dione/2-phenylisoquinoline-1,3-dione skeleton.Aya Nakagawa et al.Bioorganic & medicinal chemistry, 16(14), 7046-7054 (2008-07-01) Cell differentiation inducers derived from thalidomide.Tomomi Noguchi et al.Bioorganic & medicinal chemistry letters, 15(13), 3212-3215 (2005-06-07) Long-term plasmapheresis in conjunction with thalidomide and dexamethasone for the treatment of cutaneous ulcers and neovascular glaucoma in recalcitrant type I cryoglobulinemia.Chao H Yang et al.JAMA dermatology, 150(4), 426-428 (2014-02-21) Lenalidomide combined with R-CHOP overcomes negative prognostic impact of non-germinal center B-cell phenotype in newly diagnosed diffuse large B-Cell lymphoma: a phase II study.Grzegorz S Nowakowski et al.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 33(3), 251-257 (2014-08-20) Best treatment strategies in high-risk multiple myeloma: navigating a gray area.Giada Bianchi et al.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 32(20), 2125-2132 (2014-06-04) Phase I-II trial of oral cyclophosphamide, prednisone and lenalidomide for the treatment of patients with relapsed and refractory multiple myeloma.Donna E Reece et al.British journal of haematology, 168(1), 46-54 (2014-08-26) Methamphetamine accelerates cellular senescence through stimulation of de novo ceramide biosynthesis.Giuseppe Astarita et al.PloS one, 10(2), e0116961-e0116961 (2015-02-12) IgG4-related skin disease--reply.Saskia Ingen-Housz-Oro et al.JAMA dermatology, 149(12), 1440-1440 (2013-12-20) Phase II study of pomalidomide in high-risk relapsed and refractory multiple myeloma.S Z Usmani et al.Leukemia, 28(12), 2413-2415 (2014-08-26) Single-step approach for fabrication of vancomycin-bonded silica monolith as chiral stationary phase.Ming-Lung Hsieh et al.Journal of chromatography. A, 1358, 208-216 (2014-07-23) First line and salvage therapy with total therapy 3-based treatment for multiple myeloma- an extended single center experience.Eli Muchtar et al.Leukemia research, 38(12), 1401-1406 (2014-07-26) RNA interference screening identifies lenalidomide sensitizers in multiple myeloma, including RSK2.Yuan Xiao Zhu et al.Blood, 125(3), 483-491 (2014-11-15) The role of TNF-alpha/NF-kappa B pathway on the up-regulation of voltage-gated sodium channel Nav1.7 in DRG neurons of rats with diabetic neuropathy.Yangliang Huang et al.Neurochemistry international, 75, 112-119 (2014-06-04) Successful multimodal treatment for aggressive metastatic and recurrent fibrolamellar hepatocellular carcinoma in a child.Arzu Okur et al.Journal of pediatric hematology/oncology, 36(5), e328-e332 (2014-03-13) Lenalidomide and dexamethasone in transplant-ineligible patients with myeloma.Lotfi Benboubker et al.The New England journal of medicine, 371(10), 906-917 (2014-09-04) Additive Renoprotection by Pioglitazone and Fenofibrate against Inflammatory, Oxidative and Apoptotic Manifestations of Cisplatin Nephrotoxicity: Modulation by PPARs.Mai M Helmy et al.PloS one, 10(11), e0142303-e0142303 (2015-11-05) Long-term treatment of thalidomide ameliorates amyloid-like pathology through inhibition of β-secretase in a mouse model of Alzheimer's disease.Ping He et al.PloS one, 8(2), e55091-e55091 (2013-02-14) A method for human teratogen detection by geometrically confined cell differentiation and migration.Jiangwa Xing et al.Scientific reports, 5, 10038-10038 (2015-05-13) Novel generation of agents with proven clinical activity in multiple myeloma.María-Victoria Mateos et al.Seminars in oncology, 40(5), 618-633 (2013-10-19) Effect of Thalidomide on Clinical Remission in Children and Adolescents with Ulcerative Colitis Refractory to Other Immunosuppressives: Pilot Randomized Clinical Trial.Marzia Lazzerini et al.Inflammatory bowel diseases, 21(8), 1739-1749 (2015-07-18) Teratogen screening using transcriptome profiling of differentiating human embryonic stem cells.Yoav Mayshar et al.Journal of cellular and molecular medicine, 15(6), 1393-1401 (2010-06-22) [Treatment of multiple myeloma with lenalidomide and bortezomib combination therapy].Yusuke Takeda et al.Nihon rinsho. Japanese journal of clinical medicine, 73(1), 130-136 (2015-01-30) Phase 2 study of carfilzomib, thalidomide, and dexamethasone as induction/consolidation therapy for newly diagnosed multiple myeloma.Pieter Sonneveld et al.Blood, 125(3), 449-456 (2014-11-16) Safety and tolerability of ixazomib, an oral proteasome inhibitor, in combination with lenalidomide and dexamethasone in patients with previously untreated multiple myeloma: an open-label phase 1/2 study.Shaji K Kumar et al.The Lancet. Oncology, 15(13), 1503-1512 (2014-12-03) Multivariate time-dependent comparison of the impact of lenalidomide in lower-risk myelodysplastic syndromes with chromosome 5q deletion.Joaquín Sánchez-García et al.British journal of haematology, 166(2), 189-201 (2014-04-11) Expression of cereblon protein assessed by immunohistochemicalstaining in myeloma cells is associated with superior response of thalidomide- and lenalidomide-based treatment, but not bortezomib-based treatment, in patients with multiple myeloma.Shang-Yi Huang et al.Annals of hematology, 93(8), 1371-1380 (2014-04-02) Thalidomide inhibits the replication of human immunodeficiency virus type 1.S Makonkawkeyoon et al.Proceedings of the National Academy of Sciences of the United States of America, 90(13), 5974-5978 (1993-07-01) Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).Zhichao Liu et al.PLoS computational biology, 7(12), e1002310-e1002310 (2011-12-24) Reply to D’Amato et al. and Zeldis et al.: Screening of thalidomide derivatives in chicken and zebrafish embryos.Neil Vargesson et al.Proceedings of the National Academy of Sciences of the United States of America, 110(50), E4820-E4820 (2014-01-29) IgG4-related skin disease.Julia S Lehman et al.JAMA dermatology, 149(12), 1439-1440 (2013-12-20) A phase II trial of a multi-agent oral antiangiogenic (metronomic) regimen in children with recurrent or progressive cancer.Nathan J Robison et al.Pediatric blood & cancer, 61(4), 636-642 (2013-10-15) Long-term follow-up in a patient with the dermato-neuro syndrome treated with high-dose melphalan, thalidomide, and intravenous immunoglobulins for more than 7 years.T Devos et al.Annals of hematology, 93(11), 1927-1928 (2014-03-29) Inhibitors of NF-kappaB derived from thalidomide.Esperanza J Carcache de-Blanco et al.Bioorganic & medicinal chemistry letters, 17(21), 6031-6035 (2007-09-12) Current treatment for multiple myeloma.David Avigan et al.The New England journal of medicine, 371(10), 961-962 (2014-09-04) Stable and orally bio-available pro-drugs of CPS11.Aihong Huo et al.Bioorganic & medicinal chemistry letters, 21(21), 6242-6244 (2011-10-04) A matched comparison of cyclophosphamide, bortezomib and dexamethasone (CVD) versus risk-adapted cyclophosphamide, thalidomide and dexamethasone (CTD) in AL amyloidosis.C P Venner et al.Leukemia, 28(12), 2304-2310 (2014-07-17) Lenalidomide and metronomic melphalan for CMML and higher risk MDS: a phase 2 clinical study with biomarkers of angiogenesis.Rena Buckstein et al.Leukemia research, 38(7), 756-763 (2014-05-14) Randomized phase II adjuvant factorial study of dose-dense temozolomide alone and in combination with isotretinoin, celecoxib, and/or thalidomide for glioblastoma.Marta Penas-Prado et al.Neuro-oncology, 17(2), 266-273 (2014-09-23) Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.Naomi L Kruhlak et al.Toxicology mechanisms and methods, 18(2-3), 217-227 (2008-01-01) Treatment for high-risk smoldering myeloma.María-Victoria Mateos et al.The New England journal of medicine, 369(18), 1764-1765 (2013-11-01) Salvage lenalidomide in four rare oncological diseases.Petr Szturz et al.Tumori, 99(5), e251-e256 (2013-12-24) Measuring cereblon as a biomarker of response or resistance to lenalidomide and pomalidomide requires use of standardized reagents and understanding of gene complexity.Anita K Gandhi et al.British journal of haematology, 164(2), 233-244 (2013-11-12) Discovery of new orally effective analgesic and anti-inflammatory hybrid furoxanyl N-acylhydrazone derivatives.Paola Hernández et al.Bioorganic & medicinal chemistry, 20(6), 2158-2171 (2012-02-24) A randomized, investigator-masked, double-blind, placebo-controlled trial on thalidomide in severe cutaneous sarcoidosis.Catherine Droitcourt et al.Chest, 146(4), 1046-1054 (2014-06-20) Discovering a new analogue of thalidomide which may be used as a potent modulator of TNF-alpha production.Miguel Fernández Braña et al.European journal of medicinal chemistry, 44(9), 3533-3542 (2009-04-28) Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): identification of phenmedipham and amperozide as FAAH inhibitors.Fabien Vincent et al.Bioorganic & medicinal chemistry letters, 19(23), 6793-6796 (2009-10-24) The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins.Gang Lu et al.Science (New York, N.Y.), 343(6168), 305-309 (2013-12-03) The preclinical activity of lenalidomide in indolent urothelial carcinoma.Weiguo Jian et al.Anticancer research, 34(7), 3383-3389 (2014-07-02) Identifying off-target effects and hidden phenotypes of drugs in human cells.Marnie L MacDonald et al.Nature chemical biology, 2(6), 329-337 (2006-05-09) The influence of retinoic Acid and thalidomide on the radiosensitivity of u343 glioblastoma cells.Dušan Milanović et al.Anticancer research, 34(4), 1885-1891 (2014-04-03) Chemical genetics reveals a complex functional ground state of neural stem cells.Phedias Diamandis et al.Nature chemical biology, 3(5), 268-273 (2007-04-10) The effect of thalidomide on ethanol-induced gastric mucosal damage in mice: involvement of inflammatory cytokines and nitric oxide.Keyvan Amirshahrokhi et al.Chemico-biological interactions, 225, 63-69 (2014-12-06) Differential humoral responses against heat-shock proteins after autologous stem cell transplantation in multiple myeloma.Natalia Tovar et al.Annals of hematology, 93(1), 107-111 (2013-11-13) Early response-based intensification of primary therapy in newly diagnosed multiple myeloma patients who are eligible for autologous stem cell transplantation: phase II study.Seo-Yeon Ahn et al.Annals of hematology, 93(9), 1571-1577 (2014-04-15) An alternative dosing strategy of lenalidomide for patients with relapsed multiple myeloma.Rakesh Popat et al.British journal of haematology, 168(1), 148-151 (2014-08-12) Update on second primary malignancies in multiple myeloma: a focused review.O Landgren et al.Leukemia, 28(7), 1423-1426 (2014-01-15) In vitro anti-proliferative and anti-angiogenic activities of thalidomide dithiocarbamate analogs.Bishoy Y A El-Aarag et al.International immunopharmacology, 21(2), 283-292 (2014-05-27) Immunomodulatory drugs thalidomide and lenalidomide affect osteoblast differentiation of human bone marrow stromal cells in vitro.Bolomsky A, Schreder M, Mei?ner T, et al. Experimental Hematology, 42(7), 516-525 (2014) Efficacy and safety of lenalidomide in relapse/refractory multiple myeloma--real life experience of a tertiary cancer center.Cristina João et al.Annals of hematology, 94(1), 97-105 (2014-07-21) Autologous transplantation and maintenance therapy in multiple myeloma.Antonio Palumbo et al.The New England journal of medicine, 371(10), 895-905 (2014-09-04) Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.Denis Fourches et al.Chemical research in toxicology, 23(1), 171-183 (2009-12-18) Adverse drug reaction: pomalidomide-induced liver injury.Rajwanth R Veluswamy et al.Lancet (London, England), 383(9935), 2125-2126 (2014-06-24) New thalidomide analogues derived through Sonogashira or Suzuki reactions and their TNF expression inhibition profiles.Scott G Stewart et al.Bioorganic & medicinal chemistry, 18(2), 650-662 (2009-12-26) Osteolytic lesions in patients with relapse of diffuse large B-cell lymphoma treated with lenalidomide.Nikolai Schuelper et al.Annals of hematology, 93(11), 1929-1930 (2014-04-09) Long-term outcomes of thalidomide in refractory Crohn's disease.M E Gerich et al.Alimentary pharmacology & therapeutics, 41(5), 429-437 (2014-12-17) "A fortuitous combination of circumstances".Sagar Lonial Blood, 122(16), 2768-2769 (2013-10-19) [Immunomodulatory effects of lenalidomide].Hiroshi Handa et al.Nihon rinsho. Japanese journal of clinical medicine, 73(1), 156-161 (2015-01-30) Thalidomide-induced angiopoietin 2, Notch1 and Dll4 downregulation under hypoxic condition in tissues with gastrointestinal vascular malformation and human umbilical vein endothelial cells.Qian Feng et al.Journal of digestive diseases, 15(2), 85-95 (2013-11-14) Clarithromycin overcomes resistance to lenalidomide and dexamethasone in multiple myeloma.Nilanjan Ghosh et al.American journal of hematology, 89(8), E116-E120 (2014-04-12) Drug updates and approvals: 2014 in review.Jeff Sigler The Nurse practitioner, 39(12), 14-23 (2014-10-29) TLR9 signalling in microglia attenuates seizure-induced aberrant neurogenesis in the adult hippocampus.Taito Matsuda et al.Nature communications, 6, 6514-6514 (2015-03-10) Bortezomib, melphalan, prednisone (VMP) versus melphalan, prednisone, thalidomide (MPT) in elderly newly diagnosed multiple myeloma patients: A retrospective case-matched study.Fortunato Morabito et al.American journal of hematology, 89(4), 355-362 (2013-11-26) Pomalidomide is strongly antiangiogenic and teratogenic in relevant animal models.Robert J D'Amato et al.Proceedings of the National Academy of Sciences of the United States of America, 110(50), E4818-E4818 (2013-12-05) IL-6 signaling contributes to radioresistance of prostate cancer through key DNA repair-associated molecules ATM, ATR, and BRCA 1/2.Xiaodong Chen et al.Journal of cancer research and clinical oncology, 145(6), 1471-1484 (2019-04-26) Medicine. How thalidomide works against cancer.A Keith Stewart Science (New York, N.Y.), 343(6168), 256-257 (2014-01-18) Thalidomide: Still an important second-line treatment in refractory cutaneous lupus erythematosus?Isabelle Baret et al.The Journal of dermatological treatment, 26(2), 173-177 (2014-04-16) Thalidomide controls adipose tissue inflammation associated with high-fat diet-induced obesity in mice.Patricia Z Nakamitsu et al.Endocrine, metabolic & immune disorders drug targets, 15(2), 151-158 (2014-12-03) Effect of thalidomide on clinical remission in children and adolescents with refractory Crohn disease: a randomized clinical trial.Marzia Lazzerini et al.JAMA, 310(20), 2164-2173 (2013-11-28) Treatment with lenalidomide (Revlimid®), cyclophosphamide (Endoxan®) and prednisone (REP) in relapsed/refractory multiple myeloma patients: results of a single centre retrospective study.N Zelis et al.Acta clinica Belgica, 69(2), 98-103 (2014-04-15) A novel effect of thalidomide and its analogs: suppression of cereblon ubiquitination enhances ubiquitin ligase function.Yaobin Liu et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(12), 4829-4839 (2015-08-02) Synergistic antitumor activity of lenalidomide with the BET bromodomain inhibitor CPI203 in bortezomib-resistant mantle cell lymphoma.A Moros et al.Leukemia, 28(10), 2049-2059 (2014-04-12) Higher frequency of peripheral blood follicular regulatory T cells in patients with new onset ankylosing spondylitis.Yuxing Shan et al.Clinical and experimental pharmacology & physiology, 42(2), 154-161 (2014-10-28) Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells.Jan Krönke et al.Science (New York, N.Y.), 343(6168), 301-305 (2013-12-03) Assessment of proteasome concentration and chymotrypsin-like activity in plasma of patients with newly diagnosed multiple myeloma.Agnieszka Oldziej et al.Leukemia research, 38(8), 925-930 (2014-06-14) Lenalidomide desensitization for delayed hypersensitivity reactions in 5 patients with multiple myeloma.Min Jung Lee et al.British journal of haematology, 167(1), 127-131 (2014-05-16) Lenalidomide and rituximab for the initial treatment of patients with chronic lymphocytic leukemia: a multicenter clinical-translational study from the chronic lymphocytic leukemia research consortium.Danelle F James et al.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 32(19), 2067-2073 (2014-05-29) Effect of thalidomide on clinical remission in children and adolescents with refractory Crohn disease: a randomized clinical trial.Marzia Lazzerini et al.JAMA, 310(20), 2164-2173 (2013-11-28) Protective effects of thalidomide on pulmonary injuries in a rat model of paraquat intoxication.Dan Li et al.Journal of inflammation (London, England), 12, 46-46 (2015-07-30) Accelerated therapeutic progress in diffuse large B cell lymphoma.Qingqing Cai et al.Annals of hematology, 93(4), 541-556 (2014-01-01) Thalidomide controls adipose tissue inflammation associated with high-fat diet-induced obesity in mice.Patricia Z Nakamitsu et al.Endocrine, metabolic & immune disorders drug targets, 15(2), 151-158 (2014-12-03) A randomized, investigator-masked, double-blind, placebo-controlled trial on thalidomide in severe cutaneous sarcoidosis.Catherine Droitcourt et al.Chest, 146(4), 1046-1054 (2014-06-20) Discovery of new orally effective analgesic and anti-inflammatory hybrid furoxanyl N-acylhydrazone derivatives.Paola Hernández et al.Bioorganic & medicinal chemistry, 20(6), 2158-2171 (2012-02-24) Identifying off-target effects and hidden phenotypes of drugs in human cells.Marnie L MacDonald et al.Nature chemical biology, 2(6), 329-337 (2006-05-09) Synthesis and pharmacological evaluation of pyrazine N-acylhydrazone derivatives designed as novel analgesic and anti-inflammatory drug candidates.Yolanda Karla Cupertino da Silva et al.Bioorganic & medicinal chemistry, 18(14), 5007-5015 (2010-07-06) Tubulin-polymerization inhibitors derived from thalidomide.Shunsuke Inatsuki et al.Bioorganic & medicinal chemistry letters, 15(2), 321-325 (2004-12-18) Bortezomib- and thalidomide-induced peripheral neuropathy in multiple myeloma: clinical and molecular analyses of a phase 3 study.Paola Tacchetti et al.American journal of hematology, 89(12), 1085-1091 (2014-08-28) An innovative three-dimensional gelatin foam culture system for improved study of glioblastoma stem cell behavior.Meng-Yin Yang et al.Journal of biomedical materials research. Part B, Applied biomaterials, 103(3), 618-628 (2014-06-27) Comparative effectiveness on survival of zoledronic acid versus pamidronate in multiple myeloma.K M Sanfilippo et al.Leukemia & lymphoma, 56(3), 615-621 (2014-05-23) Impact of failed response to novel agent induction in autologous stem cell transplantation for multiple myeloma.Sung-Eun Lee et al.Annals of hematology, 93(4), 627-634 (2013-10-03) Mature results of MM-011: a phase I/II trial of liposomal doxorubicin, vincristine, dexamethasone, and lenalidomide combination therapy followed by lenalidomide maintenance for relapsed/refractory multiple myeloma.Aleksandr Lazaryan et al.American journal of hematology, 89(4), 349-354 (2013-11-26) Synthesis and TNF expression inhibitory properties of new thalidomide analogues derived via Heck cross coupling.Scott G Stewart et al.Bioorganic & medicinal chemistry letters, 17(21), 5819-5824 (2007-09-14) Thalidomide can promote erythropoiesis by induction of STAT5 and repression of external pathway of apoptosis resulting in increased expression of GATA-1 transcription factor.Norbert Grzasko et al.Pharmacological reports : PR, 67(6), 1193-1200 (2015-10-21) Lenalidomide in relapsed and refractory multiple myeloma disease: feasibility and benefits of long-term treatment.Manola Zago et al.Annals of hematology, 93(12), 1993-1999 (2014-07-01) Medicine. How thalidomide works against cancer.A Keith Stewart Science (New York, N.Y.), 343(6168), 256-257 (2014-01-18) [Thalidomide, cereblon and multiple myeloma].Toshihiko Ogura Nihon rinsho. Japanese journal of clinical medicine, 73(1), 149-155 (2015-01-30) Thalidomide-prednisone maintenance following autologous stem cell transplant for multiple myeloma: effect on thrombin generation and procoagulant markers in NCIC CTG MY.10.Michael J Kovacs et al.British journal of haematology, 168(4), 511-517 (2014-10-11) Preclinical and clinical results with pomalidomide in the treatment of relapsed/refractory multiple myeloma.Tomer M Mark et al.Leukemia research, 38(5), 517-524 (2014-04-03) Thalidomide inhibits alternative activation of macrophages in vivo and in vitro: a potential mechanism of anti-asthmatic effect of thalidomide.Hyun Seung Lee et al.PloS one, 10(4), e0123094-e0123094 (2015-04-24) Antitumor activity of thalidomide in refractory multiple myeloma.S Singhal et al.The New England journal of medicine, 341(21), 1565-1571 (1999-11-24) Novel agents for multiple myeloma to overcome resistance in phase III clinical trials.Robert Z Orlowski Seminars in oncology, 40(5), 634-651 (2013-10-19) The Use of Chemical-Chemical Interaction and Chemical Structure to Identify New Candidate Chemicals Related to Lung Cancer.Lei Chen et al.PloS one, 10(6), e0128696-e0128696 (2015-06-06) High Stoichiometry Phosphorylation of Talin at T144/T150 or S446 Produces Contrasting Effects on Calpain-mediated Talin Cleavage and Cell Migration.Youjun Li et al.Journal of Cancer, 7(12), 1645-1652 (2016-10-05) Functional communication between PKC-targeted cardiac troponin I phosphorylation sites.Sarah E Lang et al.Archives of biochemistry and biophysics, 627, 1-9 (2017-06-08) Differential effects of phosphorylation of regions of troponin I in modifying cooperative activation of cardiac thin filaments.Patti L Engel et al.Journal of molecular and cellular cardiology, 47(3), 359-364 (2009-05-12) Secondary phosphorylation in myocytes expressing FLAG-tagged and non-tagged phospho-mimetic cardiac troponin I.Sarah E Lang et al.Data in brief, 15, 562-566 (2017-10-27) Phosphorylation of CtBP1 by cAMP-dependent protein kinase modulates induction of CYP17 by stimulating partnering of CtBP1 and 2.Eric B Dammer et al.The Journal of biological chemistry, 283(11), 6925-6934 (2008-01-11)

Remarks