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2-Chloropyrimidine-5-carbaldehyde | CAS:933702-55-7
2-Chloropyrimidine-5-carbaldehyde
  • Name:2-Chloropyrimidine-5-carbaldehyde
  • CAS:933702-55-7
  • Synonyms:
  • Molecular Formula:C5H3ClN2O
  • Molecular Weight:142.54
  • EINESC:

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Density 1.432

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Description of route of synthesis: Dissolve 2-chloro-5-vinylpyrimidine in 1,4-dioxane, add 2,6-dimethylpyridine, use osmium tetroxide as a catalyst, and add sodium periodate in batches to perform dihydroxylation and oxidative cleavage of carbon carbon double bonds, oxidizing vinyl to aldehyde; After the reaction is completed, the solid salt is removed by filtration, and the filtrate is extracted, concentrated, and purified to obtain 2-chloropyrimidine-5-formaldehyde.

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