Melting point	180-182 ºC

Symbol(GHS)	Xi
Hazard Codes	R36/37/38
SDS/MSDS	S26;S36

Source	SDS/MSDS Samples
Alfa-Aesar	View & Download
Sigma-Aldrich	View & Download
Georganics	View & Download

Synthetic Route

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Articles

Peer-Reviewed Papers

Lymphomatosis cerebri presenting as a rapidly progressive dementia with a high methylmalonic acid.G Leschziner et al.Journal of neurology, 258(8), 1489-1493 (2011-03-03) The psoriasis drug monomethylfumarate is a potent nicotinic acid receptor agonist.Hua Tang et al.Biochemical and biophysical research communications, 375(4), 562-565 (2008-08-30) Pharmacokinetics of anti-psoriatic fumaric acid esters in psoriasis patients.Martin Rostami-Yazdi et al.Archives of dermatological research, 302(7), 531-538 (2010-06-25) Fumarate reductase: structural and mechanistic insights from the catalytic reduction of 2-methylfumarate.Caroline Wardrope et al.FEBS letters, 580(6), 1677-1680 (2006-02-25) Influence of monomethylfumarate on monocytic cytokine formation--explanation for adverse and therapeutic effects in psoriasis?K Asadullah et al.Archives of dermatological research, 289(11), 623-630 (1998-01-28) Induction of the cystine/glutamate exchanger SLC7A11 in retinal pigment epithelial cells by the antipsoriatic drug monomethylfumarate.Sudha Ananth et al.Investigative ophthalmology & visual science, 54(3), 1592-1602 (2013-02-14) In vitro pharmacokinetics of anti-psoriatic fumaric acid esters.Nicolle H R Litjens et al.BMC pharmacology, 4, 22-22 (2004-10-14) A methylaspartate cycle in haloarchaea.Maria Khomyakova et al.Science (New York, N.Y.), 331(6015), 334-337 (2011-01-22) Clinical characteristics and gene mutation analysis of methylmalonic aciduria.Qin Yi et al.Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 31(3), 384-389 (2011-06-15) Urinary methylmalonic acid in patients with acute myocardial infarction.Turgay Celik et al.Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 18(3), 217-222 (2009-04-08) Monomethylfumarate affects polarization of monocyte-derived dendritic cells resulting in down-regulated Th1 lymphocyte responses.Nicolle H R Litjens et al.European journal of immunology, 34(2), 565-575 (2004-02-10) Plausible molecular mechanism for activation by fumarate and electron transfer of the dopamine beta-mono-oxygenase reaction.D Shyamali Wimalasena et al.The Biochemical journal, 367(Pt 1), 77-85 (2002-06-01) Cytokine secretion pattern in treatment of lymphocytes of multiple sclerosis patients with fumaric acid esters.Samaneh Zoghi et al.Immunological investigations, 40(6), 581-596 (2011-04-23) Highly sensitive GC/MS/MS method for quantitation of amino and nonamino organic acids.Hans F N Kvitvang et al.Analytical chemistry, 83(7), 2705-2711 (2011-03-11) Effects of fumaric acids on cuprizone induced central nervous system de- and remyelination in the mouse.Darius Moharregh-Khiabani et al.PloS one, 5(7), e11769-e11769 (2010-07-30) Carbon Dots from Citric Acid and its Intermediates Formed by Thermal Decomposition.Robert Ludmerczki et al.Chemistry (Weinheim an der Bergstrasse, Germany), 25(51), 11963-11974 (2019-06-30) Reduction of fumarate, mesaconate and crotonate by Mfr, a novel oxygen-regulated periplasmic reductase in Campylobacter jejuni.Edward Guccione et al.Environmental microbiology, 12(3), 576-591 (2009-11-19) A metabolomic strategy revealed the role of JA and SA balance in Clematis terniflora DC. Response to UVB radiation and dark.Bingxian Yang et al.Physiologia plantarum, 167(2), 232-249 (2018-11-24) Reversing the effects of formalin fixation with citraconic anhydride and heat: a universal antigen retrieval method.Shigeki Namimatsu et al.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 53(1), 3-11 (2005-01-08) Hyperkalemia after acute metabolic decompensation in two children with vitamin B12-unresponsive methylmalonic acidemia and normal renal function.I Pela et al.Clinical nephrology, 66(1), 63-66 (2006-08-02) In-depth mapping carboxylic acid metabolome reveals the potential biomarkers in colorectal cancer through characteristic fragment ions and metabolic flux.Xiqing Bian et al.Analytica chimica acta, 1128, 62-71 (2020-08-23) Effects of fumaric acid esters on blood-brain barrier tight junction proteins.Karelle Bénardais et al.Neuroscience letters, 555, 165-170 (2013-10-01) Antihepatotoxic activity of monomethyl fumarate isolated from Fumaria indica.K S Rao et al.Journal of ethnopharmacology, 60(3), 207-213 (1998-06-05) Synthesis, characterization and reactivity ratio study of poly(di(tri-n-butyltin) citraconate-co-N-vinylimidazole).Salem S Al-Deyab et al.Molecules (Basel, Switzerland), 15(7), 4750-4756 (2010-07-27) Downregulation of endothelial adhesion molecules by dimethylfumarate, but not monomethylfumarate, and impairment of dynamic lymphocyte-endothelial cell interactions.Katrin Wallbrecht et al.Experimental dermatology, 20(12), 980-985 (2011-10-15) Interactions between aluminium, iron and silicon in Cucumber sativus L. grown under acidic conditions.Nikolai P Bityutskii et al.Journal of plant physiology, 218, 100-108 (2017-08-19) Catalytic (transfer) deuterogenation in D2O as deuterium source with H2 and HCO2H as electron sources.Yuichiro Himeda et al.Dalton transactions (Cambridge, England : 2003), (32)(32), 6286-6288 (2009-08-06) A new antigen retrieval technique for human brain tissue.Raúl Alelú-Paz et al.PloS one, 3(10), e3378-e3378 (2008-10-15) The antipsoriatic agent monomethylfumarate has antiproliferative, prodifferentiative, and anti-inflammatory effects on keratinocytes.Inas Helwa et al.The Journal of pharmacology and experimental therapeutics, 352(1), 90-97 (2014-10-22) Effects of monomethylfumarate on dendritic cell differentiation.N H R Litjens et al.The British journal of dermatology, 154(2), 211-217 (2006-01-26) Vitamin B12, cognition, and brain MRI measures: a cross-sectional examination.C C Tangney et al.Neurology, 77(13), 1276-1282 (2011-09-29) Serum amine oxidase can specifically recognize and oxidize aminohexyl (AH) chains on AH-Sepharose support: single-step affinity immobilization.O Befani et al.Biotechnology and applied biochemistry, 28 ( Pt 2), 99-104 (1998-10-02)

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