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Proguanil and cycloguanil are organic cation transporter and multidrug and toxin extrusion substrates.Maarten van der Velden et al.Malaria journal, 16(1), 422-422 (2017-10-25) Efficacy and tolerability of a new formulation of artesunate-mefloquine for the treatment of uncomplicated malaria in adult in Senegal: open randomized trial.Roger C K Tine et al.Malaria journal, 11, 416-416 (2012-12-14) Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors.Mahadeo A Sukhai et al.The Journal of clinical investigation, 123(1), 315-328 (2012-12-04) Proguanil and cycloguanil are organic cation transporter and multidrug and toxin extrusion substrates.Maarten van der Velden et al.Malaria journal, 16(1), 422-422 (2017-10-25) Schizontemia as an indicator of severe malaria.Noppadon Tangpukdee et al.The Southeast Asian journal of tropical medicine and public health, 44(5), 740-743 (2014-01-21) Primaquine for reducing Plasmodium falciparum transmission.Patricia M Graves et al.The Cochrane database of systematic reviews, 9(9), CD008152-CD008152 (2012-09-14) Mirincamycin, an old candidate for malaria combination treatment and prophylaxis in the 21st century: in vitro interaction profiles with potential partner drugs in continuous culture and field isolates.Peter Starzengruber et al.Malaria journal, 13, 228-228 (2014-06-12) Histamine induces ATP release from human subcutaneous fibroblasts, via pannexin-1 hemichannels, leading to Ca2+ mobilization and cell proliferation.Ana Rita Pinheiro et al.The Journal of biological chemistry, 288(38), 27571-27583 (2013-08-07) Efficacy and tolerability of a new formulation of artesunate-mefloquine for the treatment of uncomplicated malaria in adult in Senegal: open randomized trial.Roger C K Tine et al.Malaria journal, 11, 416-416 (2012-12-14) Malaria.Nicholas J White et al.Lancet (London, England), 383(9918), 723-735 (2013-08-21) Identification of plumbagin and sanguinarine as effective chemotherapeutic agents for treatment of schistosomiasisZhang SM and Coultas KA International Journal for Parasitology, Drugs and Drug Resistance, 3(11), 28-34 (2013) Efficacy of dihydroartemisinin-piperaquine for treatment of uncomplicated Plasmodium falciparum and Plasmodium vivax in Cambodia, 2008 to 2010.Rithea Leang et al.Antimicrobial agents and chemotherapy, 57(2), 818-826 (2012-12-05) Preliminary investigation of the contribution of CYP2A6, CYP2B6, and UGT1A9 polymorphisms on artesunate-mefloquine treatment response in Burmese patients with Plasmodium falciparum malaria.Papichaya Phompradit et al.The American journal of tropical medicine and hygiene, 91(2), 361-366 (2014-06-04) Malaria.Nicholas J White et al.Lancet (London, England), 383(9918), 723-735 (2013-08-21) Chemosensitization potential of P-glycoprotein inhibitors in malaria parasites.Laura M Alcantara et al.Experimental parasitology, 134(2), 235-243 (2013-04-02) Addition of exogenous NAD+ prevents mefloquine-induced neuroaxonal and hair cell degeneration through reduction of caspase-3-mediated apoptosis in cochlear organotypic culturesDing D, et al. Testing, 8(11), e79817-e79817 (2013) Effects of the combined artesunate and mefloquine antimalarial drugs on rat embryos.A C Boareto et al.Human & experimental toxicology, 32(9), 930-941 (2013-02-21) Comparison between Flow Cytometry, Microscopy, and Lactate Dehydrogenase-Based Enzyme-Linked Immunosorbent Assay for Plasmodium falciparum Drug Susceptibility Testing under Field Conditions.Charles J Woodrow et al.Journal of clinical microbiology, 53(10), 3296-3303 (2015-08-14) The anti-malarial drug Mefloquine disrupts central autonomic and respiratory control in the working heart brainstem preparation of the rat.Varinder K Lall et al.Journal of biomedical science, 19, 103-103 (2012-12-18) Factors associated with cerebral malaria.Bipin Adhikari et al.The Southeast Asian journal of tropical medicine and public health, 44(6), 941-949 (2014-01-24) Favourable outcome of progressive multifocal leukoencephalopathy with mefloquine treatment in combination with antiretroviral therapy in an HIV-infected patient.E Adachi et al.International journal of STD & AIDS, 23(8), 603-605 (2012-08-30) First case of Plasmodium knowlesi infection in a Japanese traveller returning from Malaysia.Ryutaro Tanizaki et al.Malaria journal, 12, 128-128 (2013-04-17) Drugs for treating urinary schistosomiasis.Christine V Kramer et al.The Cochrane database of systematic reviews, 8(8), CD000053-CD000053 (2014-08-08) Failure of mefloquine therapy in progressive multifocal leukoencephalopathy: report of two Japanese patients without human immunodeficiency virus infection.Zen Kobayashi et al.Journal of the neurological sciences, 324(1-2), 190-194 (2012-11-28) Efficacy of mefloquine intermittent preventive treatment in pregnancy against Schistosoma haematobium infection in Gabon: a nested randomized controlled assessor-blinded clinical trial.Arti Basra et al.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 56(6), e68-e75 (2012-11-24) The Plasmodium falciparum cytoplasmic translation apparatus: a promising therapeutic target not yet exploited by clinically approved anti-malarialsSheridan CM, et al. Malaria Journal, 17(1), 465-465 (2018) Studying the effect of chloroquine on sporozoite-induced protection and immune responses in Plasmodium berghei malaria.Else M Bijker et al.Malaria journal, 14, 130-130 (2015-04-19) Study on the developmental toxicity of combined artesunate and mefloquine antimalarial drugs on rats.Ana Cláudia Boareto et al.Reproductive toxicology (Elmsford, N.Y.), 34(4), 658-664 (2012-10-17) Treatment of suspected hyper-reactive malarial splenomegaly (HMS) in pregnancy with mefloquine.Juthamas Jaroensuk et al.The American journal of tropical medicine and hygiene, 90(4), 609-611 (2014-03-05) Assessing the utility of an anti-malarial pharmacokinetic-pharmacodynamic model for aiding drug clinical development.Sophie Zaloumis et al.Malaria journal, 11, 303-303 (2012-08-31) Humanized mouse model of glucose 6-phosphate dehydrogenase deficiency for in vivo assessment of hemolytic toxicity.Rosemary Rochford et al.Proceedings of the National Academy of Sciences of the United States of America, 110(43), 17486-17491 (2013-10-09) Progressive Multifocal Leukoencephalopathy with Immune Reconstitution Inflammatory Syndrome (PML-IRIS): two case reports of successful treatment with mefloquine and a review of the literature.Barnaby E Young et al.Annals of the Academy of Medicine, Singapore, 41(12), 620-624 (2013-01-11) An in vivo drug screening model using glucose-6-phosphate dehydrogenase deficient mice to predict the hemolytic toxicity of 8-aminoquinolines.Peng Zhang et al.The American journal of tropical medicine and hygiene, 88(6), 1138-1145 (2013-03-27) Effect of single nucleotide polymorphisms in cytochrome P450 isoenzyme and N-acetyltransferase 2 genes on the metabolism of artemisinin-based combination therapies in malaria patients from Cambodia and Tanzania.Eva Maria Staehli Hodel et al.Antimicrobial agents and chemotherapy, 57(2), 950-958 (2012-12-12) Some Ototoxic Drugs Destroy Cochlear Support Cells Before Damaging Sensory Hair Cells.Dalian Ding et al.Neurotoxicity research, 37(3), 743-752 (2020-01-31) Investigation of the in vitro gender-specific partitioning of mefloquine in malarial infected red blood cells and plasma.Nongluk Seethorn et al.The American journal of tropical medicine and hygiene, 89(4), 737-741 (2013-09-05) Biowaiver monographs for immediate release solid oral dosage forms: mefloquine hydrochloride.S Strauch et al.Journal of pharmaceutical sciences, 100(1), 11-21 (2010-07-06) Spontaneous activity in the developing gerbil auditory cortex in vivo involves GABAergic transmission.V C Kotak et al.Neuroscience, 226, 130-144 (2012-09-19) The story of artesunate-mefloquine (ASMQ), innovative partnerships in drug development: case study.Susan Wells et al.Malaria journal, 12, 68-68 (2013-02-26) Regulation of hypoxia-induced autophagy in glioblastoma involves ATG9ARahim SAA, et al. British Journal of Cancer, 117(6), 813-813 (2017) [New combination therapy against malaria].Merete Kile Holtermann Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 132(15), 1741-1741 (2012-10-26) JPC-2997, a new aminomethylphenol with high in vitro and in vivo antimalarial activities against blood stages of Plasmodium.Geoffrey W Birrell et al.Antimicrobial agents and chemotherapy, 59(1), 170-177 (2014-10-22) Inhibition of influenza virus replication by targeting broad host cell pathways.Isabelle Marois et al.PloS one, 9(10), e110631-e110631 (2014-10-22) The use of a prodrug approach to minimize potential CNS exposure of next generation quinoline methanols while maintaining efficacy in in vivo animal models.Jason C Sousa et al.European journal of drug metabolism and pharmacokinetics, 39(4), 231-236 (2014-04-08) Defining the timing of action of antimalarial drugs against Plasmodium falciparum.Danny W Wilson et al.Antimicrobial agents and chemotherapy, 57(3), 1455-1467 (2013-01-16) The antimalarial drug mefloquine enhances TP53 premature termination codon readthrough by aminoglycoside G418.Michael W Ferguson et al.PloS one, 14(5), e0216423-e0216423 (2019-05-24) Antagonistic cooperativity between crystal growth modifiers.Wenchuan Ma et al.Nature, 577(7791), 497-501 (2020-01-17) Artemisinin-resistant Plasmodium falciparum in Pursat province, western Cambodia: a parasite clearance rate study.Chanaki Amaratunga et al.The Lancet. Infectious diseases, 12(11), 851-858 (2012-09-04) Influence of mefloquine administration during early pregnancy on rat embryonic development.Mai Helmy El-Dakdoky Toxicology mechanisms and methods, 25(2), 105-112 (2014-11-20) Artemisinin resistance containment project in Thailand. II: Responses to mefloquine-artesunate combination therapy among falciparum malaria patients in provinces bordering Cambodia.Wichai Satimai et al.Malaria journal, 11, 300-300 (2012-08-30) The design, synthesis, in silico ADME profiling, antiplasmodial and antimycobacterial evaluation of new arylamino quinoline derivatives.Matshawandile Tukulula et al.European journal of medicinal chemistry, 57, 259-267 (2012-10-16)

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