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Articles

Peer-Reviewed Papers

Chemical modulation of endocytic sorting augments adeno-associated viral transductionBerry GE and Asokan A The Journal of Biological Chemistry, 291(2), 939-947 (2016) The Deubiquitinating Enzyme Inhibitor PR-619 is a Potent DNA Topoisomerase II Poison.Ian G Cowell et al.Molecular pharmacology, 96(5), 562-572 (2019-09-14) Dynamic Regulation of Mitochondrial Import by the Ubiquitin System.Lilian Phu et al.Molecular cell, 77(5), 1107-1123 (2020-03-07) Genome-scale screening of deubiquitinase subfamily identifies USP3 as a stabilizer of Cdc25A regulating cell cycle in cancer.Soumyadip Das et al.Cell death and differentiation, 27(11), 3004-3020 (2020-05-18) Development of two novel high-throughput assays to quantify ubiquitylated proteins in cell lysates: application to screening of new anti-malarials.Lydia Mata-Cantero et al.Malaria journal, 14, 200-200 (2015-05-15) A Human DUB Protein Array for Clarification of Linkage Specificity of Polyubiquitin Chain and Application to Evaluation of Its Inhibitors.Hirotaka Takahashi et al.Biomedicines, 8(6) (2020-06-10) Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase.Sajjan Koirala et al.Cell reports, 32(3), 107922-107922 (2020-07-23) NRBP1-Containing CRL2/CRL4A Regulates Amyloid β Production by Targeting BRI2 and BRI3 for Degradation.Takashi Yasukawa et al.Cell reports, 30(10), 3478-3491 (2020-03-12) The PINK1 kinase-driven ubiquitin ligase Parkin promotes mitochondrial protein import through the presequence pathway in living cells.M Jacoupy et al.Scientific reports, 9(1), 11829-11829 (2019-08-16) VCP Machinery Mediates Autophagic Degradation of Empty Argonaute.Hotaka Kobayashi et al.Cell reports, 28(5), 1144-1153 (2019-08-01) Inhibition of deubiquitinases alters gamete ubiquitination states and sperm-oocyte binding ability in pigs.Yang Wang et al.Animal reproduction science, 187, 64-73 (2017-10-17) Anti-apoptotic effect by the suppression of IRF1 as a downstream of Wnt/β-catenin signaling in colorectal cancer cells.Tomoyuki Ohsugi et al.Oncogene, 38(32), 6051-6064 (2019-07-12) Global Landscape and Dynamics of Parkin and USP30-Dependent Ubiquitylomes in iNeurons during Mitophagic Signaling.Alban Ordureau et al.Molecular cell, 77(5), 1124-1142 (2020-03-07) The anaphase promoting complex impacts repair choice by protecting ubiquitin signalling at DNA damage sites.Kyungsoo Ha et al.Nature communications, 8, 15751-15751 (2017-06-13) Small Molecule Enhancers of Endosome-to-Cytosol Import Augment Anti-tumor Immunity.Patrycja Kozik et al.Cell reports, 32(2), 107905-107905 (2020-07-16) The Lectin-like Domain of TNF Increases ENaC Open Probability through a Novel Site at the Interface between the Second Transmembrane and C-terminal Domains of the α-Subunit.Rudolf Lucas et al.The Journal of biological chemistry, 291(45), 23440-23451 (2016-09-21) Dynamics of PARKIN-Dependent Mitochondrial Ubiquitylation in Induced Neurons and Model Systems Revealed by Digital Snapshot Proteomics.Alban Ordureau et al.Molecular cell, 70(2), 211-227 (2018-04-17) USP8 Deubiquitinates the Leptin Receptor and Is Necessary for Leptin-Mediated Synapse Formation.Tyler Bland et al.Endocrinology, 160(8), 1982-1998 (2019-06-15) Teuvincenone F Suppresses LPS-Induced Inflammation and NLRP3 Inflammasome Activation by Attenuating NEMO Ubiquitination.Xibao Zhao et al.Frontiers in pharmacology, 8, 565-565 (2017-09-08) Chemical Modulation of Endocytic Sorting Augments Adeno-associated Viral Transduction.Garrett E Berry et al.The Journal of biological chemistry, 291(2), 939-947 (2015-11-04) Inhibition of USP9X Downregulates JAK2-V617F and Induces Apoptosis Synergistically with BH3 Mimetics Preferentially in Ruxolitinib-Persistent JAK2-V617F-Positive Leukemic Cells.Hiroki Akiyama et al.Cancers, 12(2) (2020-02-14) Cytosolic iron-sulfur assembly is evolutionarily tuned by a cancer-amplified ubiquitin ligaseWeon JL, et sl. Molecular Cell, 69(1), 113-125 (2018) Large-scale identification of ubiquitination sites by mass spectrometryUdeshi ND, et al. Nature Protocols, 8(10), 1950-1950 (2013) Molecular hydrogen inhibits lipopolysaccharide-triggered NLRP3 inflammasome activation in macrophages by targeting the mitochondrial reactive oxygen species.Jian-Dong Ren et al.Biochimica et biophysica acta, 1863(1), 50-55 (2015-10-22) Grb2-Mediated Recruitment of USP9X to LAT Enhances Themis Stability following Thymic Selection.Anne Garreau et al.Journal of immunology (Baltimore, Md. : 1950), 199(8), 2758-2766 (2017-09-08) A Nucleolar Isoform of the Drosophila Ubiquitin Specific Protease dUSP36 Regulates MYC-Dependent Cell Growth.Dominique Thevenon et al.Frontiers in cell and developmental biology, 8, 506-506 (2020-07-09) Inflammasomes-dependent regulation of IL-1β secretion induced by the virulent Mycobacterium bovis Beijing strain in THP-1 macrophages.Yang Zhou et al.Antonie van Leeuwenhoek, 108(1), 163-171 (2015-05-20) Iruka Eliminates Dysfunctional Argonaute by Selective Ubiquitination of Its Empty State.Hotaka Kobayashi et al.Molecular cell, 73(1), 119-129 (2018-12-07) A pair of E3 ubiquitin ligases compete to regulate filopodial dynamics and axon guidance.Nicholas P Boyer et al.The Journal of cell biology, 219(1) (2019-12-11) Oxidation of SQSTM1/p62 mediates the link between redox state and protein homeostasis.Bernadette Carroll et al.Nature communications, 9(1), 256-256 (2018-01-19)

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