Melting point	218-219 ºC
Boiling point	221 ºC
Flash point	87 ºC
Density	1.070

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Source	SDS/MSDS Samples
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Oakwood	View & Download
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Synthetic Route

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Articles

Peer-Reviewed Papers

Influence of Carbopol 71G-NF on the release of dextromethorphan hydrobromide from extended-release matrix tablets.Mohamed H Fayed et al.Pharmaceutical development and technology, 18(5), 971-981 (2011-06-07) Efficacy of dextromethorphan and cyclosporine a for acute encephalopathy.Muneaki Matsuo et al.Pediatric neurology, 48(3), 200-205 (2013-02-20) Influence of CYP2D6 activity on pre-emptive analgesia by the N-methyl-D-aspartate antagonist dextromethorphan in a randomized controlled trial of acute pain.Georg B Ehret et al.Pain physician, 16(1), 45-56 (2013-01-24) Effect of abiraterone acetate plus prednisone on the pharmacokinetics of dextromethorphan and theophylline in patients with metastatic castration-resistant prostate cancer.K N Chi et al.Cancer chemotherapy and pharmacology, 71(1), 237-244 (2012-10-16) Acute cognitive effects of high doses of dextromethorphan relative to triazolam in humans.Lawrence P Carter et al.Drug and alcohol dependence, 128(3), 206-213 (2012-09-20) Common ocular effects reported to a poison control center after systemic absorption of drugs in therapeutic and toxic doses.Ann Slattery et al.Current opinion in ophthalmology, 25(6), 519-523 (2014-09-17) [Dextromethorphan (DXM): new methods of intoxications among teenagers--a case description].Ewa Tomczak et al.Archiwum medycyny sadowej i kryminologii, 62(3), 197-202 (2013-05-09) Fixed drug eruption due to dextromethorphan with tolerance to other opioids.G Davila-Fernández et al.Journal of investigational allergology & clinical immunology, 23(4), 281-282 (2013-08-24) Anti-dyskinetic mechanisms of amantadine and dextromethorphan in the 6-OHDA rat model of Parkinson's disease: role of NMDA vs. 5-HT1A receptors.Melanie A Paquette et al.The European journal of neuroscience, 36(9), 3224-3234 (2012-08-07) Low-dose dextromethorphan, a NADPH oxidase inhibitor, reduces blood pressure and enhances vascular protection in experimental hypertension.Tao-Cheng Wu et al.PloS one, 7(9), e46067-e46067 (2012-10-11) Honey for acute cough in children.Olabisi Oduwole et al.The Cochrane database of systematic reviews, 12(12), CD007094-CD007094 (2014-12-24) How often do false-positive phencyclidine urine screens occur with use of common medications?Arvind Rengarajan et al.Clinical toxicology (Philadelphia, Pa.), 51(6), 493-496 (2013-05-24) Hepatic Cyp2d and Cyp26a1 mRNAs and activities are increased during mouse pregnancy.Ariel R Topletz et al.Drug metabolism and disposition: the biological fate of chemicals, 41(2), 312-319 (2012-11-15) The use of the 13C-dextromethorphan breath test for phenotyping CYP2D6 in breast cancer patients using tamoxifen: association with CYP2D6 genotype and serum endoxifen levels.F L Opdam et al.Cancer chemotherapy and pharmacology, 71(3), 593-601 (2012-12-12) Pharmacogenomic/pharmacokinetic assessment of a four-probe cocktail for CYPs and OATPs following oral microdosing.Ichiro Ieiri et al.International journal of clinical pharmacology and therapeutics, 50(10), 689-700 (2012-08-03) Sigma-1 receptor agonists directly inhibit Nav1.2/1.4 channels.Xiao-Fei Gao et al.PloS one, 7(11), e49384-e49384 (2012-11-10) Pharmacokinetic and pharmacodynamic alterations in the Roux-en-Y gastric bypass recipients.Sweta Tandra et al.Annals of surgery, 258(2), 262-269 (2012-12-12) Simultaneous determination of dextromethorphan and dextrophan in rat plasma by LC-MS/MS and its application to a pharmacokinetic study.Renai Xu et al.Die Pharmazie, 67(6), 485-489 (2012-07-25) Dextromethorphan attenuates LPS-induced adhesion molecule expression in human endothelial cells.Shinn-Jong Jiang et al.Microcirculation (New York, N.Y. : 1994), 20(2), 190-201 (2012-11-13) Endoxifen levels and its association with CYP2D6 genotype and phenotype: evaluation of a southern Brazilian population under tamoxifen pharmacotherapy.Marina V Antunes et al.Therapeutic drug monitoring, 34(4), 422-431 (2012-07-11) Development and optimization of dextromethorphan hydrobromide oral disintegrating tablets: effect of formulation and process variables.Haitham Fady Mostafa et al.Pharmaceutical development and technology, 18(2), 454-463 (2012-08-14) Suicidal and homicidal behaviors related to dextromethorphan abuse in a middle-aged woman.Dhruv Modi et al.Journal of addiction medicine, 7(2), 143-144 (2013-02-08) Concentration-dependent inhibitory effects of baicalin on the metabolism of dextromethorphan, a dual probe of CYP2D and CYP3A, in rats.Xin Tian et al.Chemico-biological interactions, 203(2), 522-529 (2013-03-06) Dextromethorphan attenuated inflammation and combined opioid use in humans undergoing methadone maintenance treatment.Shiou-Lan Chen et al.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 7(4), 1025-1033 (2012-09-20) Enzyme kinetic and molecular docking studies for the inhibitions of miltirone on major human cytochrome P450 isozymes.Xuelin Zhou et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 20(3-4), 367-374 (2012-10-30) Mechanism of action of dextromethorphan/quinidine:comparison with ketamine.Stephen M Stahl CNS spectrums, 18(5), 225-227 (2013-09-21) Inhibitory effects of kale ingestion on metabolism by cytochrome P450 enzymes in rats.Izumi Yamasaki et al.Biomedical research (Tokyo, Japan), 33(4), 235-242 (2012-09-15) CYP2D6 phenotype indicative for optimized antiestrogen efficacy associates with outcome in early breast cancer patients.Andreas Trojan et al.Cancer chemotherapy and pharmacology, 71(2), 301-306 (2012-10-27) Fatalities involving acetaminophen combination products reported to United States poison centers.Suzanne Doyon et al.Clinical toxicology (Philadelphia, Pa.), 51(10), 941-948 (2013-10-18) Viscerosomatic facilitation in a subset of IBS patients, an effect mediated by N-methyl-D-aspartate receptors.G Nicholas Verne et al.The journal of pain : official journal of the American Pain Society, 13(9), 901-909 (2012-09-11)

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