Melting point	74-77 ºC
Boiling point	135-140 ºC (20 mmHg)

Symbol(GHS)	Xi
Hazard Codes	R36/37/38;R43
SDS/MSDS	S26;S36/37

Source	SDS/MSDS Samples
Alfa-Aesar	View & Download
Sigma-Aldrich	View & Download
TCI	View & Download

Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

Inhibitory effects of steroidal timosaponins isolated from the rhizomes of Anemarrhena asphodeloides against passive cutaneous anaphylaxis reaction and pruritus.Bomi Lee et al.Immunopharmacology and immunotoxicology, 32(3), 357-363 (2010-01-26) Anti-proliferative and pro-apoptotic effect of Smilax glabra Roxb. extract on hepatoma cell lines.Fei Sa et al.Chemico-biological interactions, 171(1), 1-14 (2007-11-13) Antidepressant-like effects of sarsasapogenin from Anemarrhena asphodeloides BUNGE (Liliaceae).Li-Xiang Ren et al.Biological & pharmaceutical bulletin, 29(11), 2304-2306 (2006-11-02) The apoptotic effect of sarsasapogenin from Anemarrhena asphodeloides on HepG2 human hepatoma cells.Wenna Bao et al.Cell biology international, 31(9), 887-892 (2007-04-03) Simultaneous analysis of diosgenin and sarsasapogenin in Asparagus officinalis byproduct by thin-layer chromatography.Liwei Wang et al.Phytochemical analysis : PCA, 22(1), 14-17 (2010-08-28) Thrombin/PAR-1 activation induces endothelial damages via NLRP1 inflammasome in gestational diabetes.Yue Liu et al.Biochemical pharmacology, 175, 113849-113849 (2020-02-16) PYM50028, a novel, orally active, nonpeptide neurotrophic factor inducer, prevents and reverses neuronal damage induced by MPP+ in mesencephalic neurons and by MPTP in a mouse model of Parkinson's disease.Naomi P Visanji et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 22(7), 2488-2497 (2008-03-28) [Studies on accumulation of active ingredients, N, P and K in Anemarrhena asphodeloides].Juan Chen et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 32(15), 1504-1507 (2007-11-02) Antiviral activity of Solanum paniculatum extract and constituents.Ydia M Valadares et al.Zeitschrift fur Naturforschung. C, Journal of biosciences, 64(11-12), 813-818 (2010-02-18) An improved facile method for extraction and determination of steroidal saponins in Tribulus terrestris by focused microwave-assisted extraction coupled with GC-MS.Tianlin Li et al.Journal of separation science, 32(23-24), 4167-4175 (2009-11-06) Regioselective cleavage of 22-oxo-23-spiroketals. Novel cholestanic frameworks with pyranone and cyclopentenone E rings on the side chain.Yliana López et al.Steroids, 77(5), 534-541 (2012-02-16) Smilagenin attenuates beta amyloid (25-35)-induced degeneration of neuronal cells via stimulating the gene expression of brain-derived neurotrophic factor.R Zhang et al.Neuroscience, 210, 275-285 (2012-03-24) Deacylation reactions of 20-acetyl dinorcholanic lactones and 20,23-diacetyl furost-22-enes.Ma Guadalupe Hernández-Linares et al.Steroids, 75(3), 240-244 (2009-12-26) The protective potential of Yucca schidigera (Sarsaponin 30) against nitrite-induced oxidative stress in rats.I Hakki Cigerci et al.Journal of natural medicines, 63(3), 311-317 (2009-05-13) A novel sarsasapogenin glycoside from Asparagus racemosus elicits protective immune responses against HBsAg.Tabasum Sidiq et al.Immunology letters, 135(1-2), 129-135 (2010-11-03) Regulation of M1-receptor mRNA stability by smilagenin and its significance in improving memory of aged rats.Yaer Hu et al.Neurobiology of aging, 31(6), 1010-1019 (2008-08-05) A double-blind, placebo-controlled study of traditional Chinese medicine sarsasapogenin added to risperidone in patients with negative symptoms dominated schizophrenia.Shi-Fu Xiao et al.Neuroscience bulletin, 27(4), 258-268 (2011-07-27) Role of glial cell derived neurotrophic factor in the protective effect of smilagenin on rat mesencephalic dopaminergic neurons damaged by MPP+.Yongfang Zhang et al.FEBS letters, 582(6), 956-960 (2008-02-27) Steroids from the roots of Asparagus officinalis and their cytotoxic activity.Xue-Feng Huang et al.Journal of integrative plant biology, 50(6), 717-722 (2008-08-21) A sensitive indirect competitive enzyme-linked immunosorbent assay for the detection of sarsasapogenin in rat plasma.Jing Wang et al.Acta pharmacologica Sinica, 31(8), 984-989 (2010-08-06) Antidepressant activity of sarsasapogenin from Anemarrhena asphodeloides Bunge (Liliaceae).L X Ren et al.Die Pharmazie, 62(1), 78-79 (2007-02-14) Diacetoxyiodobenzene-mediated synthesis of unnatural furospirostane sapogenins derived from diosgenin and tigogenin.Jacqueline Sánchez-Flores et al.Steroids, 78(9), 798-802 (2013-05-28) Role of CREB in the regulatory action of sarsasapogenin on muscarinic M1 receptor density during cell aging.Haiyan Hu et al.FEBS letters, 584(8), 1549-1552 (2010-03-11) Sarsasapogenin alleviates diabetic nephropathy through suppression of chronic inflammation by down-regulating PAR-1: In vivo and in vitro study.Zhuang-Zhuang Tang et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 78, 153314-153314 (2020-09-04) Sarsasapogenin induces apoptosis via the reactive oxygen species-mediated mitochondrial pathway and ER stress pathway in HeLa cells.Shuying Shen et al.Biochemical and biophysical research communications, 441(2), 519-524 (2014-01-03) Mitochondrial ROS burst as an early sign in sarsasapogenin-induced apoptosis in HepG2 cells.Yuan Ni et al.Cell biology international, 32(3), 337-343 (2008-02-12) Tigogenin inhibits adipocytic differentiation and induces osteoblastic differentiation in mouse bone marrow stromal cells.Hua Zhou et al.Molecular and cellular endocrinology, 270(1-2), 17-22 (2007-03-17) Inhibition of human rheumatoid arthritis synovial cell survival by hecogenin and tigogenin is associated with increased apoptosis, p38 mitogen-activated protein kinase activity and upregulation of cyclooxygenase-2.Bertrand Liagre et al.International journal of molecular medicine, 20(4), 451-460 (2007-09-06) Synthesis of "glycospirostanes" via ring-closing metathesis.Dorota Czajkowska et al.Steroids, 74(13-14), 1073-1079 (2009-09-15)

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