Melting point	196.5 ºC**
Boiling point	190-191 ºC***
Density	1.227±0.06 g/cm3 (20 º

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Source	SDS/MSDS Samples
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Synthetic Route

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Peer-Reviewed Papers

Structure and Function of Stator Units of the Bacterial Flagellar Motor.Mònica Santiveri et al.Cell, 183(1), 244-257 (2020-09-16) Structures of the stator complex that drives rotation of the bacterial flagellum.Justin C Deme et al.Nature microbiology, 5(12), 1553-1564 (2020-09-16) Mapping Polyclonal Antibody Responses in Non-human Primates Vaccinated with HIV Env Trimer Subunit Vaccines.Bartek Nogal et al.Cell reports, 30(11), 3755-3765 (2020-03-19) Structural Basis for Activation of the Heterodimeric GABAB Receptor.Yoojoong Kim et al.Journal of molecular biology, 432(22), 5966-5984 (2020-10-16) The mitochondrial transporter SLC25A25 links ciliary TRPP2 signaling and cellular metabolism.Alexis Hofherr et al.PLoS biology, 16(8), e2005651-e2005651 (2018-08-07) Hybridization of TEDOR and NCX MAS solid-state NMR experiments for simultaneous acquisition of heteronuclear correlation spectra and distance measurements.T Gopinath et al.Journal of biomolecular NMR, 73(3-4), 141-153 (2019-02-26) Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling.Emma J Fenech et al.eLife, 9 (2020-07-03) Structure of a proton-dependent lipid transporter involved in lipoteichoic acids biosynthesis.Bing Zhang et al.Nature structural & molecular biology, 27(6), 561-569 (2020-05-06) Structural Mechanism of Functional Modulation by Gene Splicing in NMDA Receptors.Michael C Regan et al.Neuron, 98(3), 521-529 (2018-04-17) Cryo-EM structures of fungal and metazoan mitochondrial calcium uniporters.Rozbeh Baradaran et al.Nature, 559(7715), 580-584 (2018-07-12) Structure of Human ATG9A, the Only Transmembrane Protein of the Core Autophagy Machinery.Carlos M Guardia et al.Cell reports, 31(13), 107837-107837 (2020-07-02) Structure of the human gonadotropin-releasing hormone receptor GnRH1R reveals an unusual ligand binding mode.Wei Yan et al.Nature communications, 11(1), 5287-5287 (2020-10-22) Identification of druggable small molecule antagonists of the Plasmodium falciparum hexose transporter PfHT and assessment of ligand access to the glucose permeation pathway via FLAG-mediated protein engineering.Monique R Heitmeier et al.PloS one, 14(5), e0216457-e0216457 (2019-05-10) Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly.Longfei Wang et al.Molecular cell, 80(3), 501-511 (2020-10-17) Quality Control of Protein Complex Assembly by a Transmembrane Recognition Factor.Nivedita Natarajan et al.Molecular cell, 77(1), 108-119 (2019-11-05) Discovery of a Regulatory Subunit of the Yeast Fatty Acid Synthase.Kashish Singh et al.Cell, 180(6), 1130-1143 (2020-03-12) Crystal structure of the Frizzled 4 receptor in a ligand-free state.Shifan Yang et al.Nature, 560(7720), 666-670 (2018-08-24) Structural Basis of the Proton Sensitivity of Human GluN1-GluN2A NMDA Receptors.Jin-Bao Zhang et al.Cell reports, 25(13), 3582-3590 (2018-12-28) Subunit NDUFV3 is present in two distinct isoforms in mammalian complex I.Hannah R Bridges et al.Biochimica et biophysica acta, 1858(3), 197-207 (2016-12-13) Conformational Sensors and Domain Swapping Reveal Structural and Functional Differences between β-Arrestin Isoforms.Eshan Ghosh et al.Cell reports, 28(13), 3287-3299 (2019-09-26) Facile preparation and characterization of fibrous carbon nanomaterial from waste polyethylene terephthalate.Xing Zhou et al.Waste management (New York, N.Y.), 107, 172-181 (2020-04-15) Structure of a novel enzyme that catalyzes acyl transfer to alcohols in aqueous conditions.Irimpan Mathews et al.Biochemistry, 46(31), 8969-8979 (2007-07-20) Influenza hemagglutinin membrane anchor.Donald J Benton et al.Proceedings of the National Academy of Sciences of the United States of America, 115(40), 10112-10117 (2018-09-19) Gating of human TRPV3 in a lipid bilayer.Zengqin Deng et al.Nature structural & molecular biology, 27(7), 635-644 (2020-06-24) Conserved cytoplasmic domains promote Hrd1 ubiquitin ligase complex formation for ER-associated degradation (ERAD).Jasmin Schulz et al.Journal of cell science, 130(19), 3322-3335 (2017-08-23) Occurrence of short chain aliphatic diols in human blood: identification by gas chromatography-mass spectrometry.L Sisfontes et al.Clinica chimica acta; international journal of clinical chemistry, 155(2), 117-122 (1986-03-16) The ER membrane protein complex promotes biogenesis of sterol-related enzymes maintaining cholesterol homeostasis.Norbert Volkmar et al.Journal of cell science, 132(2) (2018-12-24) Symmetry mismatch in the MS-ring of the bacterial flagellar rotor explains the structural coordination of secretion and rotation.Steven Johnson et al.Nature microbiology, 5(7), 966-975 (2020-04-15) A Novel Polar Core and Weakly Fixed C-Tail in Squid Arrestin Provide New Insight into Interaction with Rhodopsin.Abhishek Bandyopadhyay et al.Journal of molecular biology, 430(21), 4102-4118 (2018-08-19) Cryo-EM structures of the ATP release channel pannexin 1.Zengqin Deng et al.Nature structural & molecular biology, 27(4), 373-381 (2020-04-02) Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand.Xianjun Zhang et al.Nature communications, 8, 15383-15383 (2017-05-18) Structural basis of coreceptor recognition by HIV-1 envelope spike.Md Munan Shaik et al.Nature, 565(7739), 318-323 (2018-12-14) Thermal stability of purified and reconstituted CFTR in a locked open channel conformation.Luba A Aleksandrov et al.Protein expression and purification, 116, 159-166 (2015-09-20) Smoothened stimulation by membrane sterols drives Hedgehog pathway activity.Ishan Deshpande et al.Nature, 571(7764), 284-288 (2019-07-03) Structure of the substrate-engaged SecA-SecY protein translocation machine.Chengying Ma et al.Nature communications, 10(1), 2872-2872 (2019-06-30) Atomic structure of the eukaryotic intramembrane RAS methyltransferase ICMT.Melinda M Diver et al.Nature, 553(7689), 526-529 (2018-01-18) Interactions and cooperativity between P-glycoprotein structural domains determined by thermal unfolding provides insights into its solution structure and function.Zhengrong Yang et al.Biochimica et biophysica acta, 1859(1), 48-60 (2016-10-27) Structural insights into differences in G protein activation by family A and family B GPCRs.Daniel Hilger et al.Science (New York, N.Y.), 369(6503) (2020-08-01) An allosteric network in spastin couples multiple activities required for microtubule severing.Colby R Sandate et al.Nature structural & molecular biology, 26(8), 671-678 (2019-07-10) Phase-plate cryo-EM structure of a class B GPCR-G-protein complex.Yi-Lynn Liang et al.Nature, 546(7656), 118-123 (2017-04-25) Developing a High-Throughput Assay for the Integral Membrane Glycerol 3-Phosphate Acyltransferase.Yannan Tang et al.Assay and drug development technologies, 17(6), 267-274 (2019-08-14) Phosphorus-containing derivatives of 2, 2-dimethyl-1, 3-propanediolMcCONNELL RL and Coover Jr HW The Journal of Organic Chemistry, 24.5, 630-635 (1959) Structure of formylpeptide receptor 2-Gi complex reveals insights into ligand recognition and signaling.Youwen Zhuang et al.Nature communications, 11(1), 885-885 (2020-02-16) Cryo-electron microscopy structure of the glucagon receptor with a dual-agonist peptide.Rulue Chang et al.The Journal of biological chemistry, 295(28), 9313-9325 (2020-05-07) Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-Gi Complex Structures.Tian Hua et al.Cell, 180(4), 655-665 (2020-02-01) The structure-energy landscape of NMDA receptor gating.Drew M Dolino et al.Nature chemical biology, 13(12), 1232-1238 (2017-10-11) Cryo-EM structure of the insect olfactory receptor Orco.Joel A Butterwick et al.Nature, 560(7719), 447-452 (2018-08-17) Structure of a Signaling Cannabinoid Receptor 1-G Protein Complex.Kaavya Krishna Kumar et al.Cell, 176(3), 448-458 (2019-01-15) Distinctive Activation Mechanism for Angiotensin Receptor Revealed by a Synthetic Nanobody.Laura M Wingler et al.Cell, 176(3), 479-490 (2019-01-15) Toward a Structural Understanding of Class B GPCR Peptide Binding and Activation.Yi-Lynn Liang et al.Molecular cell, 77(3), 656-668 (2020-02-01) Structural basis for human sterol isomerase in cholesterol biosynthesis and multidrug recognition.Tao Long et al.Nature communications, 10(1), 2452-2452 (2019-06-06) Crystal Structure of a Plant Multidrug and Toxic Compound Extrusion Family Protein.Yoshiki Tanaka et al.Structure (London, England : 1993), 25(9), 1455-1460 (2017-09-07) Structure and dynamics of the active human parathyroid hormone receptor-1.Li-Hua Zhao et al.Science (New York, N.Y.), 364(6436), 148-153 (2019-04-13) Mechanism of modulation of AMPA receptors by TARP-γ8.Elisa Carrillo et al.The Journal of general physiology, 152(1) (2019-11-22) Triblock copolymers based on ε-caprolactone and trimethylene carbonate for the 3D printing of tissue engineering scaffolds.Aysun Güney et al.The International journal of artificial organs, 40(4), 176-184 (2017-02-07) Functional competence of a partially engaged GPCR-β-arrestin complex.Punita Kumari et al.Nature communications, 7, 13416-13416 (2016-11-09) Insights into the structure and assembly of a bacterial cellulose secretion system.Petya Violinova Krasteva et al.Nature communications, 8(1), 2065-2065 (2017-12-14) Structural Basis of Human KCNQ1 Modulation and Gating.Ji Sun et al.Cell, 180(2), 340-347 (2019-12-31) Structural basis for GPR40 allosteric agonism and incretin stimulation.Joseph D Ho et al.Nature communications, 9(1), 1645-1645 (2018-04-27) The role of interfacial lipids in stabilizing membrane protein oligomers.Kallol Gupta et al.Nature, 541(7637), 421-424 (2017-01-13) Synthesis of 6-membered cyclic carbonates from 1, 3-diols and low CO2 pressure: a novel mild strategy to replace phosgene reagentsGregory GL, et al. Royal Society of Chemistry Advances, 5.49 , 39404-39408 (2015) Interplay between Penicillin-binding proteins and SEDS proteins promotes bacterial cell wall synthesis.Sophie Leclercq et al.Scientific reports, 7, 43306-43306 (2017-02-25) The structural arrangement at intersubunit interfaces in homomeric kainate receptors.Douglas B Litwin et al.Scientific reports, 9(1), 6969-6969 (2019-05-08) Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein.Yan Zhang et al.Nature, 546(7657), 248-253 (2017-05-26) Molecular structures of the human Slo1 K+ channel in complex with β4.Xiao Tao et al.eLife, 8 (2019-12-10) HIV envelope trimer-elicited autologous neutralizing antibodies bind a region overlapping the N332 glycan supersite.Bartek Nogal et al.Science advances, 6(23), eaba0512-eaba0512 (2020-06-18) Cryo-EM structure of the human α1β3γ2 GABAA receptor in a lipid bilayer.Duncan Laverty et al.Nature, 565(7740), 516-520 (2019-01-04) The yeast mitochondrial pyruvate carrier is a hetero-dimer in its functional state.Sotiria Tavoulari et al.The EMBO journal, 38(10) (2019-04-14) Structure and mutagenic analysis of the lipid II flippase MurJ from Escherichia coli.Sanduo Zheng et al.Proceedings of the National Academy of Sciences of the United States of America, 115(26), 6709-6714 (2018-06-13) Structure of the posttranslational Sec protein-translocation channel complex from yeast.Samuel Itskanov et al.Science (New York, N.Y.), 363(6422), 84-87 (2018-12-14) Cryo-EM Structure of the Human Cannabinoid Receptor CB2-Gi Signaling Complex.Changrui Xing et al.Cell, 180(4), 645-654 (2020-02-01) Structure Reveals a Mechanism of CRISPR-RNA-Guided Nuclease Recruitment and Anti-CRISPR Viral Mimicry.MaryClare F Rollins et al.Molecular cell, 74(1), 132-142 (2019-03-16) Neutralizing Antibody Induction by HIV-1 Envelope Glycoprotein SOSIP Trimers on Iron Oxide Nanoparticles May Be Impaired by Mannose Binding Lectin.Rajesh P Ringe et al.Journal of virology, 94(6) (2019-12-20) Dual role of a GTPase conformational switch for membrane fusion by mitofusin ubiquitylation.Ramona Schuster et al.Life science alliance, 3(1) (2019-12-21) Understanding the cellular function of TRPV2 channel through generation of specific monoclonal antibodies.Matthew R Cohen et al.PloS one, 8(12), e85392-e85392 (2014-01-07) Innervation of thermogenic adipose tissue via a calsyntenin 3β-S100b axis.Xing Zeng et al.Nature, 569(7755), 229-235 (2019-05-03) Low-temperature thermal properties of 2, 2-dimethyl-1, 3-propanediol and its deuterated analoguesKamae R, et al The Journal of Chemical Thermodynamics, 33.5, 471-484 (2001) Liquid-Liquid Phase Transition Drives Intra-chloroplast Cargo Sorting.Min Ouyang et al.Cell, 180(6), 1144-1159 (2020-03-15) Small-Molecule Positive Allosteric Modulators of the β2-Adrenoceptor Isolated from DNA-Encoded Libraries.Seungkirl Ahn et al.Molecular pharmacology, 94(2), 850-861 (2018-05-18) Conformational plasticity in the selectivity filter of the TRPV2 ion channel.Lejla Zubcevic et al.Nature structural & molecular biology, 25(5), 405-415 (2018-05-08) Structural basis of arrestin-3 activation and signaling.Qiuyan Chen et al.Nature communications, 8(1), 1427-1427 (2017-11-12) Structural basis for PtdInsP2-mediated human TRPML1 regulation.Michael Fine et al.Nature communications, 9(1), 4192-4192 (2018-10-12) Activation of the α2B adrenoceptor by the sedative sympatholytic dexmedetomidine.Daopeng Yuan et al.Nature chemical biology, 16(5), 507-512 (2020-03-11) Mechanism of NMDA receptor channel block by MK-801 and memantine.Xianqiang Song et al.Nature, 556(7702), 515-519 (2018-04-20) Atomic structure of the innexin-6 gap junction channel determined by cryo-EM.Atsunori Oshima et al.Nature communications, 7, 13681-13681 (2016-12-03) Structure of a MacAB-like efflux pump from Streptococcus pneumoniae.Hong-Bo Yang et al.Nature communications, 9(1), 196-196 (2018-01-18) The substrate specificity switch FlhB assembles onto the export gate to regulate type three secretion.Lucas Kuhlen et al.Nature communications, 11(1), 1296-1296 (2020-03-12) Structural basis for σ1 receptor ligand recognition.Hayden R Schmidt et al.Nature structural & molecular biology, 25(10), 981-987 (2018-10-07) Structural basis for dual-mode inhibition of the ABC transporter MsbA.Hoangdung Ho et al.Nature, 557(7704), 196-201 (2018-05-04) Hrd1 forms the retrotranslocation pore regulated by auto-ubiquitination and binding of misfolded proteins.Vedran Vasic et al.Nature cell biology, 22(3), 274-281 (2020-02-26) Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein.Yan Zhang et al.Nature, 546(7657), 248-253 (2017-05-26) Cryo-EM structure of the human α1β3γ2 GABAA receptor in a lipid bilayer.Duncan Laverty et al.Nature, 565(7740), 516-520 (2019-01-04) Bioprocess development for biolubricant production using microbial oil derived via fermentation from confectionery industry wastes.Aikaterini Papadaki et al.Bioresource technology, 267, 311-318 (2018-07-22) PtdIns(4,5)P2 stabilizes active states of GPCRs and enhances selectivity of G-protein coupling.Hsin-Yung Yen et al.Nature, 559(7714), 423-427 (2018-07-12) Cryo-EM structures of undocked innexin-6 hemichannels in phospholipids.Batuujin Burendei et al.Science advances, 6(7), eaax3157-eaax3157 (2020-02-26) A bipartite structural organization defines the SERINC family of HIV-1 restriction factors.Valerie E Pye et al.Nature structural & molecular biology, 27(1), 78-83 (2020-01-08) ATP Binding Enables Substrate Release from Multidrug Resistance Protein 1.Zachary Lee Johnson et al.Cell, 172(1-2), 81-89 (2018-01-02) Study of the Phase Transitions in the Binary System NPG-TRIS for Thermal Energy Storage Applications.Sergio Santos-Moreno et al.Materials (Basel, Switzerland), 13(5) (2020-03-11) Structural basis for σ1 receptor ligand recognition.Hayden R Schmidt et al.Nature structural & molecular biology, 25(10), 981-987 (2018-10-07) Atomic structure of the innexin-6 gap junction channel determined by cryo-EM.Atsunori Oshima et al.Nature communications, 7, 13681-13681 (2016-12-03) Structural basis for dual-mode inhibition of the ABC transporter MsbA.Hoangdung Ho et al.Nature, 557(7704), 196-201 (2018-05-04) Mechanism of NMDA receptor channel block by MK-801 and memantine.Xianqiang Song et al.Nature, 556(7702), 515-519 (2018-04-20) Expression and Purification of Protease-Activated Receptor 4 (PAR4) and Analysis with Histidine Hydrogen-Deuterium Exchange.Maria de la Fuente et al.Biochemistry, 59(5), 671-681 (2020-01-21) Structural Insights into the Process of GPCR-G Protein Complex Formation.Xiangyu Liu et al.Cell, 177(5), 1243-1251 (2019-05-14) New convenient synthesis of highly regioregular poly (3-octylthiophene) based on the Suzuki coupling reactionGuillerez S and Bidan G Synt. Metals, 93.2, 123-126 (1998) A Two-Step Process for the Synthesis of Hydroxytyrosol.Paolo Ziosi et al.ChemSusChem, 11(13), 2202-2210 (2018-05-16) Conformational Complexity and Dynamics in a Muscarinic Receptor Revealed by NMR Spectroscopy.Jun Xu et al.Molecular cell, 75(1), 53-65 (2019-05-20) Architecture of a catalytically active homotrimeric plant cellulose synthase complex.Pallinti Purushotham et al.Science (New York, N.Y.), 369(6507), 1089-1094 (2020-07-11) Cdc48 regulates a deubiquitylase cascade critical for mitochondrial fusion.Tânia Simões et al.eLife, 7 (2018-01-09) Structure of a MacAB-like efflux pump from Streptococcus pneumoniae.Hong-Bo Yang et al.Nature communications, 9(1), 196-196 (2018-01-18) Molecular Basis for Hormone Recognition and Activation of Corticotropin-Releasing Factor Receptors.Shanshan Ma et al.Molecular cell, 77(3), 669-680 (2020-02-01) The substrate specificity switch FlhB assembles onto the export gate to regulate type three secretion.Lucas Kuhlen et al.Nature communications, 11(1), 1296-1296 (2020-03-12) Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target.Bing Zhang et al.Cell, 176(3), 636-648 (2019-01-27) Synthetic nanobodies as angiotensin receptor blockers.Conor McMahon et al.Proceedings of the National Academy of Sciences of the United States of America, 117(33), 20284-20291 (2020-08-06) Cryo-EM structures of PAC1 receptor reveal ligand binding mechanism.Jia Wang et al.Cell research, 30(5), 436-445 (2020-02-13) An improved yeast surface display platform for the screening of nanobody immune libraries.Tomasz Uchański et al.Scientific reports, 9(1), 382-382 (2019-01-25) Optimizing the α1B-adrenergic receptor for solution NMR studies.Matthias Schuster et al.Biochimica et biophysica acta. Biomembranes, 1862(10), 183354-183354 (2020-05-16) Optimized expression and purification of NavAb provide the structural insight into the voltage dependence.Katsumasa Irie et al.FEBS letters, 592(2), 274-283 (2017-12-24) Gating and selectivity mechanisms for the lysosomal K+ channel TMEM175.SeCheol Oh et al.eLife, 9 (2020-04-02) Domain-interface dynamics of CFTR revealed by stabilizing nanobodies.Maud Sigoillot et al.Nature communications, 10(1), 2636-2636 (2019-06-16) Synthesis and Structural Characterization of Sequential Structure and Crystallization Properties for Hydrophilic Modified Polyester.Lina Sun et al.Polymers, 12(8) (2020-08-07) Structure of a eukaryotic cyclic-nucleotide-gated channel.Minghui Li et al.Nature, 542(7639), 60-65 (2017-01-19) Structure of the human LAT1-4F2hc heteromeric amino acid transporter complex.Renhong Yan et al.Nature, 568(7750), 127-130 (2019-03-15) Structural basis for chemokine receptor CCR6 activation by the endogenous protein ligand CCL20.David Jonathan Wasilko et al.Nature communications, 11(1), 3031-3031 (2020-06-17) Structure and mechanism of the mitochondrial Ca2+ uniporter holocomplex.Minrui Fan et al.Nature, 582(7810), 129-133 (2020-06-05)

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