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2-(2-Chloroethoxy)ethanol | CAS:628-89-7
2-(2-Chloroethoxy)ethanol
  • Name:2-(2-Chloroethoxy)ethanol
  • CAS:628-89-7
  • Synonyms:Diethylene glycol monochlorohydrin
  • Molecular Formula:C4H9ClO2
  • Molecular Weight:124.57
  • EINESC:211-059-9

Description

Properties

Water Solubility soluble
Boiling point 180-185 ºC
Flash point 90 ºC
Density 1.18
Refractive index 1.4519-1.4539

Safety

Symbol(GHS) Xi
Hazard Codes R36
SDS/MSDS S26;S39

SDS

Source SDS/MSDS Samples
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Articles
Peer-Reviewed Papers
Genotoxicity of N-nitroso-N-methylurea and acetone oxime in the transgenic Drosophila carrying the human gene encoding a subunit of glutathione S-transferase.M Rysková et al.Folia biologica, 43(1), 19-24 (1997-01-01) Regulation of endothelin-1 expression in normal and transfected endothelial cells.U S Ryan et al.Journal of cardiovascular pharmacology, 22 Suppl 8, S38-S41 (1993-01-01) Acetoxime is metabolized by human and rodent hepatic cytochrome P450 enzymes to the genotoxicant and carcinogen propane 2-nitronate.C Kohl et al.Carcinogenesis, 13(7), 1091-1094 (1992-07-01) Carcinogenicity test of acetoxime in MRC-Wistar rats.S S Mirvish et al.Journal of the National Cancer Institute, 69(4), 961-962 (1982-10-01) Human phenol sulfotransferases hP-PST and hM-PST activate propane 2-nitronate to a genotoxicant.P Kreis et al.Carcinogenesis, 21(2), 295-299 (2000-02-05) Reversion of structure-activity relationships of antitumor platinum complexes by acetoxime but not hydroxylamine ligands.Stefanie Zorbas-Seifried et al.Molecular pharmacology, 71(1), 357-365 (2006-10-20) Amination of tyrosine in liver cytosol protein of male F344 rats treated with 2-nitropropane, 2-nitrobutane, 3-nitropentane, or acetoxime.R S Sodum et al.Chemical research in toxicology, 10(12), 1420-1426 (1998-01-23) Induction of hyperplastic liver nodules in Wistar and MRC-Wistar rats by phenobarbital and the liver carcinogens acetoxime, 1-nitroso-5,6-dihydrouracil and 3-nitroso-2-oxazolidinone.S S Mirvish et al.Cancer letters, 41(2), 211-216 (1988-08-15) Sex and organ differences in oxidative DNA and RNA damage due to treatment of Sprague-Dawley rats with acetoxime or 2-nitropropane.N Guo et al.Carcinogenesis, 11(9), 1659-1662 (1990-09-01) Slow oxidation of acetoxime and methylethyl ketoxime to the corresponding nitronates and hydroxy nitronates by liver microsomes from rats, mice, and humans.W Völkel et al.Toxicological sciences : an official journal of the Society of Toxicology, 47(2), 144-150 (1999-04-30) Synthesis and anticancer evaluation of benzyloxyurea derivatives.Feng Ren et al.Chemical & pharmaceutical bulletin, 62(9), 898-905 (2014-09-02) [Structure of adducts prepared from nicotinamide adenine dinucleotide and their oximes].J Torreilles et al.Biochimie, 65(4-5), 295-298 (1983-04-01) Ab initio molecular electrostatic potentials of perillartine analogues: implications for sweet-taste receptor recognition.T J Venanzi et al.Journal of medicinal chemistry, 31(10), 1879-1885 (1988-10-01) Oxidation of the ketoxime acetoxime to nitric oxide by oxygen radical-generating systems.A A Caro et al.Nitric oxide : biology and chemistry, 5(4), 413-424 (2001-08-04) Oxidative DNA and RNA damage in rat liver due to acetoxime: similarity to effects of 2-nitropropane.N S Hussain et al.Carcinogenesis, 11(6), 1013-1016 (1990-06-01)
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