
2-(2-Chloroethoxy)ethanol | CAS:628-89-7
2-(2-Chloroethoxy)ethanol
- Name:2-(2-Chloroethoxy)ethanol
- CAS:628-89-7
- Synonyms:Diethylene glycol monochlorohydrin
- Molecular Formula:C4H9ClO2
- Molecular Weight:124.57
- EINESC:211-059-9
Description
Properties
Water Solubility | soluble |
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Boiling point | 180-185 ºC |
Flash point | 90 ºC |
Density | 1.18 |
Refractive index | 1.4519-1.4539 |
Safety
Symbol(GHS) | Xi |
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Hazard Codes | R36 |
SDS/MSDS | S26;S39 |
SDS
Source | SDS/MSDS Samples |
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Alfa-Aesar | View & Download |
Sigma-Aldrich | View & Download |
TCI | View & Download |
Synthetic Route
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More
Articles
Peer-Reviewed Papers
Genotoxicity of N-nitroso-N-methylurea and acetone oxime in the transgenic Drosophila carrying the human gene encoding a subunit of glutathione S-transferase.M Rysková et al.Folia biologica, 43(1), 19-24 (1997-01-01)
Regulation of endothelin-1 expression in normal and transfected endothelial cells.U S Ryan et al.Journal of cardiovascular pharmacology, 22 Suppl 8, S38-S41 (1993-01-01)
Acetoxime is metabolized by human and rodent hepatic cytochrome P450 enzymes to the genotoxicant and carcinogen propane 2-nitronate.C Kohl et al.Carcinogenesis, 13(7), 1091-1094 (1992-07-01)
Carcinogenicity test of acetoxime in MRC-Wistar rats.S S Mirvish et al.Journal of the National Cancer Institute, 69(4), 961-962 (1982-10-01)
Human phenol sulfotransferases hP-PST and hM-PST activate propane 2-nitronate to a genotoxicant.P Kreis et al.Carcinogenesis, 21(2), 295-299 (2000-02-05)
Reversion of structure-activity relationships of antitumor platinum complexes by acetoxime but not hydroxylamine ligands.Stefanie Zorbas-Seifried et al.Molecular pharmacology, 71(1), 357-365 (2006-10-20)
Amination of tyrosine in liver cytosol protein of male F344 rats treated with 2-nitropropane, 2-nitrobutane, 3-nitropentane, or acetoxime.R S Sodum et al.Chemical research in toxicology, 10(12), 1420-1426 (1998-01-23)
Induction of hyperplastic liver nodules in Wistar and MRC-Wistar rats by phenobarbital and the liver carcinogens acetoxime, 1-nitroso-5,6-dihydrouracil and 3-nitroso-2-oxazolidinone.S S Mirvish et al.Cancer letters, 41(2), 211-216 (1988-08-15)
Sex and organ differences in oxidative DNA and RNA damage due to treatment of Sprague-Dawley rats with acetoxime or 2-nitropropane.N Guo et al.Carcinogenesis, 11(9), 1659-1662 (1990-09-01)
Slow oxidation of acetoxime and methylethyl ketoxime to the corresponding nitronates and hydroxy nitronates by liver microsomes from rats, mice, and humans.W Völkel et al.Toxicological sciences : an official journal of the Society of Toxicology, 47(2), 144-150 (1999-04-30)
Synthesis and anticancer evaluation of benzyloxyurea derivatives.Feng Ren et al.Chemical & pharmaceutical bulletin, 62(9), 898-905 (2014-09-02)
[Structure of adducts prepared from nicotinamide adenine dinucleotide and their oximes].J Torreilles et al.Biochimie, 65(4-5), 295-298 (1983-04-01)
Ab initio molecular electrostatic potentials of perillartine analogues: implications for sweet-taste receptor recognition.T J Venanzi et al.Journal of medicinal chemistry, 31(10), 1879-1885 (1988-10-01)
Oxidation of the ketoxime acetoxime to nitric oxide by oxygen radical-generating systems.A A Caro et al.Nitric oxide : biology and chemistry, 5(4), 413-424 (2001-08-04)
Oxidative DNA and RNA damage in rat liver due to acetoxime: similarity to effects of 2-nitropropane.N S Hussain et al.Carcinogenesis, 11(6), 1013-1016 (1990-06-01)
Remarks
Products protected by valid patents are not offered for sale in countries where the sale of such products constitutes a patent infringement and its liability is at buyer's risk.
Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271 +A13(1).
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