Melting point	203 ºC
Boiling point	219 ºC
Flash point	105 ºC
Density	2.438

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"Caught with a body" yet protected by law? Calling 911 for opioid overdose in the context of the Good Samaritan Law.Amanda D Latimore et al.The International journal on drug policy, 50, 82-89 (2017-10-19) Elevated CO2 does not stimulate carbon sink in a semi-arid grassland.Jian Song et al.Ecology letters, 22(3), 458-468 (2019-01-05) Design and evaluation of novel natriuretic peptide derivatives with improved pharmacokinetic and pharmacodynamic properties.Naomi Morozumi et al.Peptides, 97, 16-21 (2017-09-14) The effects of hazardous chemical exposure on cardiovascular disease in chemical products manufacturing workers.Ki-Woong Kim et al.Toxicological research, 28(4), 269-277 (2013-11-28) Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer's disease.Carmen Venegas et al.Nature, 552(7685), 355-361 (2018-01-03) Paricalcitol accelerates BACE1 lysosomal degradation and inhibits calpain-1 dependent neuronal loss in APP/PS1 transgenic mice.Yong-Gang Fan et al.EBioMedicine, 45, 393-407 (2019-07-16) Statins induce insulin-degrading enzyme secretion from astrocytes via an autophagy-based unconventional secretory pathway.Sung Min Son et al.Molecular neurodegeneration, 10, 56-56 (2015-11-02) Substrate-selective inhibitors that reprogram the activity of insulin-degrading enzyme.Juan Pablo Maianti et al.Nature chemical biology, 15(6), 565-574 (2019-05-16) Neprilysin inhibition promotes corneal wound healing.Rachel M Genova et al.Scientific reports, 8(1), 14385-14385 (2018-09-28) Peripheral delivery of a CNS targeted, metalo-protease reduces aβ toxicity in a mouse model of Alzheimer's disease.Brian Spencer et al.PloS one, 6(1), e16575-e16575 (2011-02-10) Evaluation of no evidence of progression or active disease (NEPAD) in patients with primary progressive multiple sclerosis in the ORATORIO trial.Jerry S Wolinsky et al.Annals of neurology, 84(4), 527-536 (2018-08-30) Ecosystem function in Appalachian headwater streams during an active invasion by the hemlock woolly adelgid.Robert M Northington et al.PloS one, 8(4), e61171-e61171 (2013-04-25) Effect of Pretreatment with Ultraviolet Radiation on the Physicomechanical Properties of Photocured Coir (Cocos nucifera) Fiber with 1-Ethyl-2-Pyrrolidone (1-E-2-P) Monomer.Khan MA, et al. Polymer-Plastics Technology and Engineering, 45(4), 487-494 (2006) BHBA treatment improves cognitive function by targeting pleiotropic mechanisms in transgenic mouse model of Alzheimer's disease.Yancheng Wu et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(1), 1412-1429 (2020-01-10) Replacement of the C-terminal Trp-cage of exendin-4 with a fatty acid improves therapeutic utility.Jung Gi Lee et al.Biochemical pharmacology, 151, 59-68 (2018-03-10) Profound loss of neprilysin accompanied by decreased levels of neuropeptides and increased CRP in ulcerative colitis.Zeynep Gök Sargın et al.PloS one, 12(12), e0189526-e0189526 (2017-12-13) Neuroprotection induced by Navβ2‑knockdown in APP/PS1 transgenic neurons is associated with NEP regulation.Tao Hu et al.Molecular medicine reports, 20(2), 2002-2011 (2019-07-02) Vemurafenib Limits Influenza A Virus Propagation by Targeting Multiple Signaling Pathways.Magdalena Holzberg et al.Frontiers in microbiology, 8, 2426-2426 (2018-01-10) Distinct modulation of microglial amyloid β phagocytosis and migration by neuropeptides (i).Sigal Fleisher-Berkovich et al.Journal of neuroinflammation, 7, 61-61 (2010-10-13) Contribution of amino acid region 334-335 from factor Va heavy chain to the catalytic efficiency of prothrombinase.Melissa A Barhoover et al.Biochemistry, 47(26), 6840-6850 (2008-06-10) HIV-1 increases extracellular amyloid-beta levels through neprilysin regulation in primary cultures of human astrocytes.Marta Martínez-Bonet et al.Journal of cellular physiology, 234(5), 5880-5887 (2018-01-13) Rapid on-site detection of ephedrine and its analogues used as adulterants in slimming dietary supplements by TLC-SERS.Diya Lv et al.Analytical and bioanalytical chemistry, 407(5), 1313-1325 (2014-12-30) Approaching over 10 000-fold sensitivity increase in chiral capillary electrophoresis: Cation-selective exhaustive injection and sweeping cyclodextrin-modified micellar electrokinetic chromatography.Toshiyasu Mikuma et al.Electrophoresis, 37(22), 2970-2976 (2016-08-21) Casein kinase 2 dependent phosphorylation of neprilysin regulates receptor tyrosine kinase signaling to Akt.Martin Siepmann et al.PloS one, 5(10) (2010-10-20) Human umbilical cord mesenchymal stem cell-derived neuron-like cells rescue memory deficits and reduce amyloid-beta deposition in an AβPP/PS1 transgenic mouse model.Hui Yang et al.Stem cell research & therapy, 4(4), 76-76 (2013-07-06) Profiling the Surfaceome Identifies Therapeutic Targets for Cells with Hyperactive mTORC1 Signaling.Junnian Wei et al.Molecular & cellular proteomics : MCP, 19(2), 294-307 (2019-12-04) Effect of trichostatin A on gelsolin levels, proteolysis of amyloid precursor protein, and amyloid beta-protein load in the brain of transgenic mouse model of Alzheimer's disease.Wenzhong Yang et al.Current Alzheimer research, 11(10), 1002-1011 (2014-11-12) Software-aided approach to investigate peptide structure and metabolic susceptibility of amide bonds in peptide drugs based on high resolution mass spectrometry.Tatiana Radchenko et al.PloS one, 12(11), e0186461-e0186461 (2017-11-02) Simultaneous determination of three pesticide adjuvant residues in plant-derived agro-products using liquid chromatography-tandem mass spectrometry.Hui Li et al.Journal of chromatography. A, 1528, 53-60 (2017-11-07) Hypoxia-induced down-regulation of neprilysin by histone modification in mouse primary cortical and hippocampal neurons.Zheng Wang et al.PloS one, 6(4), e19229-e19229 (2011-05-12) Bepridil decreases Aβ and calcium levels in the thalamus after middle cerebral artery occlusion in rats.Timo Sarajärvi et al.Journal of cellular and molecular medicine, 16(11), 2754-2767 (2012-07-19) Clinical relevance of neutral endopeptidase (NEP/CD10) in melanoma.Elsa F Velazquez et al.Journal of translational medicine, 5, 2-2 (2007-01-09) Phylodynamics of the emergence of influenza viruses after cross-species transmission.Leila Rahnama et al.PloS one, 8(12), e82486-e82486 (2013-12-21) Green tea reduces body fat via upregulation of neprilysin.M Muenzner et al.International journal of obesity (2005), 40(12), 1850-1855 (2016-10-05) The tomato WV gene encoding a thioredoxin protein is essential for chloroplast development at low temperature and high light intensity.Shenghua Gao et al.BMC plant biology, 19(1), 265-265 (2019-06-22) Investigation of ac-magnetic field stimulated nanoelectroporation of magneto-electric nano-drug-carrier inside CNS cells.Ajeet Kaushik et al.Scientific reports, 7, 45663-45663 (2017-04-05) Optimizing the Limit of Detection of Waveguide-Based Interferometric Biosensor Devices.Jonas Leuermann et al.Sensors (Basel, Switzerland), 19(17) (2019-08-28) Atmospheric deposition, COM Fernández-Martínez et al.Scientific reports, 7(1), 9632-9632 (2017-08-31) Unfavorable perceived neighborhood environment associates with less routine healthcare utilization: Data from the Dallas Heart Study.Joniqua N Ceasar et al.PloS one, 15(3), e0230041-e0230041 (2020-03-13) The Aversion to Tampering with Nature (ATN) Scale: Individual Differences in (Dis)comfort with Altering the Natural World.Kaitlin T Raimi et al.Risk analysis : an official publication of the Society for Risk Analysis, 40(3), 638-656 (2019-10-16) Activation of 5-HT(2C) receptor promotes the expression of neprilysin in U251 human glioma cells.Xiao-Lu Tian et al.Cellular and molecular neurobiology, 35(3), 425-432 (2014-12-03) Soluble intracellular adhesion molecule-1 secreted by human umbilical cord blood-derived mesenchymal stem cell reduces amyloid-β plaques.J-Y Kim et al.Cell death and differentiation, 19(4), 680-691 (2011-10-22) Evaluating the convergence between eddy-covariance and biometric methods for assessing carbon budgets of forests.M Campioli et al.Nature communications, 7, 13717-13717 (2016-12-15) Future improvements on performance of an EU landfill directive driven municipal solid waste management for a city in England.Dan Wang et al.Waste management (New York, N.Y.), 102, 452-463 (2019-11-19) Enhanced expression of natriuretic peptide receptor A and B in neutrophils of culprit lesions in patients with acute myocardial infarction.Masashi Nakagawa et al.Molecular medicine reports, 16(3), 3324-3330 (2017-08-03) Extensive transcriptional regulation of chromatin modifiers during human neurodevelopment.Matthias K Weng et al.PloS one, 7(5), e36708-e36708 (2012-05-17) Toxicokinetics of N-ethyl-2-pyrrolidone and its metabolites in blood, urine and amniotic fluid of rats after oral administration.Daniel Bury et al.Archives of toxicology, 93(4), 921-929 (2019-02-08) The NRF2 transcriptional target, OSGIN1, contributes to monomethyl fumarate-mediated cytoprotection in human astrocytes.Melanie S Brennan et al.Scientific reports, 7, 42054-42054 (2017-02-10) Regulation of Neprilysin Activity and Cognitive Functions in Rats After Prenatal Hypoxia.I A Zhuravin et al.Neurochemical research, 44(6), 1387-1398 (2019-04-22) How do disturbances and climate effects on carbon and water fluxes differ between multi-aged and even-aged coniferous forests?Xuguang Tang et al.The Science of the total environment, 599-600, 1583-1597 (2017-05-24) Participatory Environmentally Friendly Message Design: Influence of Message Features and User Characteristics.Annie W Y Ng et al.International journal of environmental research and public health, 17(4) (2020-02-26) Field-Deployable Reverse Transcription-Insulated Isothermal PCR (RT-iiPCR) Assay for Rapid and Sensitive Detection of Foot-and-Mouth Disease Virus.A Ambagala et al.Transboundary and emerging diseases, 64(5), 1610-1623 (2016-09-04) Antiviral activity of KR-23502 targeting nuclear export of influenza B virus ribonucleoproteins.Yejin Jang et al.Antiviral research, 134, 77-88 (2016-08-28) Human adipose tissue-derived mesenchymal stem cells secrete functional neprilysin-bound exosomes.Takeshi Katsuda et al.Scientific reports, 3, 1197-1197 (2013-02-05) Adenoviral neutral endopeptidase gene delivery in combination with paclitaxel for the treatment of prostate cancer.Katsuyuki Iida et al.International journal of oncology, 41(4), 1192-1198 (2012-08-17) Large cosolutes, small cosolutes, and dihydrofolate reductase activity.Luis C Acosta et al.Protein science : a publication of the Protein Society, 26(12), 2417-2425 (2017-10-04) Estrogen deficiency exacerbates Aβ-induced memory impairment through enhancement of neuroinflammation, amyloidogenesis and NF-ĸB activation in ovariectomized mice.Jaesuk Yun et al.Brain, behavior, and immunity, 73, 282-293 (2018-05-22) Screening of pure synthetic coating substrates for induced pluripotent stem cells and iPSC-derived neuroepithelial progenitors with short peptide based integrin array.Chenyang Jiang et al.Experimental cell research, 380(1), 90-99 (2019-04-15) Effect of penetration enhancers (pyrrolidone derivatives) on multilamellar liposomes of stratum corneum lipid: a study by UV spectroscopy and differential scanning calorimetry.Kim C-K, et al. International Journal of Pharmaceutics, 95(1), 43-50 (1993) Intrarenal Renin-Angiotensin-System Dysregulation after Kidney Transplantation.Johannes J Kovarik et al.Scientific reports, 9(1), 9762-9762 (2019-07-07) The Regulatory Functionality of Exosomes Derived from hUMSCs in 3D Culture for Alzheimer's Disease Therapy.Lingyan Yang et al.Small (Weinheim an der Bergstrasse, Germany), 16(3), e1906273-e1906273 (2019-12-17) Reducing amyloid plaque burden via ex vivo gene delivery of an Abeta-degrading protease: a novel therapeutic approach to Alzheimer disease.Matthew L Hemming et al.PLoS medicine, 4(8), e262-e262 (2007-09-01) Investigating public perceptions of carbon dioxide utilisation (CDU) technology: a mixed methods study.C R Jones et al.Faraday discussions, 183, 327-347 (2015-09-25) Expression of neutral endopeptidase, endothelin-1, and nuclear factor kappa B in prostate cancer: interrelations and associations with prostate-specific antigen recurrence after radical prostatectomy.Panagiotis J Vlachostergios et al.Prostate cancer, 2012, 452795-452795 (2012-06-06) 4-Week repeated dose oral toxicity study of N-ethyl-2-pyrrolidone in Sprague Dawley rats.A M Saillenfait et al.Regulatory toxicology and pharmacology : RTP, 81, 275-283 (2016-10-30) Alanine scan of sialorphin and its hybrids with opiorphin: synthesis, molecular modelling and effect on enkephalins degradation.Małgorzata Sobocińska et al.Amino acids (2018-05-13) A conserved influenza A virus nucleoprotein code controls specific viral genome packaging.Étori Aguiar Moreira et al.Nature communications, 7, 12861-12861 (2016-09-22) Two-step interphase microtubule disassembly aids spindle morphogenesis.Nunu Mchedlishvili et al.BMC biology, 16(1), 14-14 (2018-01-25) (-)-Epigallocatechin-3-gallate attenuates cognitive deterioration in Alzheimer's disease model mice by upregulating neprilysin expression.Xiang Chang et al.Experimental cell research, 334(1), 136-145 (2015-04-18) Degradation Paradigm of the Gut Hormone, Pancreatic Polypeptide, by Hepatic and Renal Peptidases.Joyceline Cuenco et al.Endocrinology, 158(6), 1755-1765 (2017-03-23) Sex differences in the aging pattern of renin-angiotensin system serum peptidases.A Fernández-Atucha et al.Biology of sex differences, 8, 5-5 (2017-02-09) Neprilysin inhibition in mouse islets enhances insulin secretion in a GLP-1 receptor dependent manner.Nathalie Esser et al.Islets, 10(5), 175-180 (2018-08-25) Chitosan nanoparticles via high-pressure homogenization-assisted miniemulsion crosslinking for mixed-matrix membrane adsorbers.Benjamin R Riegger et al.Carbohydrate polymers, 201, 172-181 (2018-09-23) Being moved by meaningfulness: appraisals of surpassing internal standards elicit being moved by relationships and achievements.Helen Landmann et al.Cognition & emotion, 33(7), 1387-1409 (2019-01-25) Identification of optimal device combinations for the chimney endovascular aneurysm repair technique within the PERICLES registry.Salvatore T Scali et al.Journal of vascular surgery, 68(1), 24-35 (2018-02-06) High resolution crystal structure of substrate-free human neprilysin.Stephen Moss et al.Journal of structural biology, 204(1), 19-25 (2018-06-16) Genetic deficiency in neprilysin or its pharmacological inhibition initiate excessive stress-induced alcohol consumption in mice.Björn Maul et al.PloS one, 7(11), e50187-e50187 (2012-11-28) Heterologous amyloid seeding: revisiting the role of acetylcholinesterase in Alzheimer's disease.Létitia Jean et al.PloS one, 2(7), e652-e652 (2007-07-27) Validation of the Spanish Center for Epidemiological Studies Depression and Zung Self-Rating Depression Scales: a comparative validation study.Paulo Ruiz-Grosso et al.PloS one, 7(10), e45413-e45413 (2012-10-12) Neutral endopeptidase and natriuretic peptide receptors participate in the regulation of C-type natriuretic peptide expression in renal interstitial fibrosis.Peng Hu et al.Journal of receptor and signal transduction research, 37(1), 71-83 (2016-06-10) 5-HIAA induces neprilysin to ameliorate pathophysiology and symptoms in a mouse model for Alzheimer's disease.Christian Klein et al.Acta neuropathologica communications, 6(1), 136-136 (2018-12-13) Amyloid β inhibits retinoic acid synthesis exacerbating Alzheimer disease pathology which can be attenuated by an retinoic acid receptor α agonist.Maria B Goncalves et al.The European journal of neuroscience, 37(7), 1182-1192 (2013-02-06) Changes of vegetation carbon sequestration in the tableland of Loess Plateau and its influencing factors.Jie Zhang et al.Environmental science and pollution research international, 26(22), 22160-22172 (2019-05-31) Crystal structure of peptide-bound neprilysin reveals key binding interactions.Stephen Moss et al.FEBS letters, 594(2), 327-336 (2019-09-13) Effects of angiotensin-converting-enzyme inhibitor therapy on the regulation of the plasma and cardiac tissue renin-angiotensin system in heart transplant patients.Johannes J Kovarik et al.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 36(3), 355-365 (2016-10-25) Lost in processing? Perceived healthfulness, taste and caloric content of whole and processed organic food.Marília Prada et al.Appetite, 114, 175-186 (2017-03-28) Mercury Reduces the Enzymatic Activity of Neprilysin in Differentiated SH-SY5Y Cells.Miguel Chin-Chan et al.Toxicological sciences : an official journal of the Society of Toxicology, 145(1), 128-137 (2015-02-13) Does physician experience influence the interpretability of focused echocardiography images performed by a pocket device?Xavier Bobbia et al.Scandinavian journal of trauma, resuscitation and emergency medicine, 23, 52-52 (2015-07-08) Genetic homogeneity but IgG subclass-dependent clinical variability of alloimmune membranous nephropathy with anti-neutral endopeptidase antibodies.Marina Vivarelli et al.Kidney international, 87(3), 602-609 (2015-01-08) Oleocanthal-rich extra-virgin olive oil enhances donepezil effect by reducing amyloid-β load and related toxicity in a mouse model of Alzheimer's disease.Yazan S Batarseh et al.The Journal of nutritional biochemistry, 55, 113-123 (2018-02-08) Fish oil protects the blood-brain barrier integrity in a mouse model of Alzheimer's disease.Youna Xie et al.Chinese medicine, 15, 29-29 (2020-04-08) Inverse baseline expression pattern of the NEP/neuropeptides and NFκB/proteasome pathways in androgen-dependent and androgen-independent prostate cancer cells.Anna Patrikidou et al.Cancer cell international, 11(1), 13-13 (2011-05-17) Catalpol preserves neural function and attenuates the pathology of Alzheimer's disease in mice.Jin-Zhong Huang et al.Molecular medicine reports, 13(1), 491-496 (2015-11-05) Substance P promotes wound healing in diabetes by modulating inflammation and macrophage phenotype.Ermelindo C Leal et al.The American journal of pathology, 185(6), 1638-1648 (2015-04-15) SCA8 RAN polySer protein preferentially accumulates in white matter regions and is regulated by eIF3F.Fatma Ayhan et al.The EMBO journal, 37(19) (2018-09-13) Influence of interface and position on upper airway collapsibility assessed by negative expiratory pressure.Raquel Pastrello Hirata et al.Sleep & breathing = Schlaf & Atmung, 21(3), 631-638 (2017-01-09) pH sensitivity of interfacial electron transfer at a supported graphene monolayer.Michel Wehrhold et al.Nanoscale, 11(31), 14742-14756 (2019-07-28) The nanoGRAVUR framework to group (nano)materials for their occupational, consumer, environmental risks based on a harmonized set of material properties, applied to 34 case studies.Wendel Wohlleben et al.Nanoscale, 11(38), 17637-17654 (2019-09-21) Barriers to using new needles encountered by rural Appalachian people who inject drugs: implications for needle exchange.Stephen M Davis et al.Harm reduction journal, 16(1), 23-23 (2019-04-04) Neprilysin, obesity and the metabolic syndrome.K F Standeven et al.International journal of obesity (2005), 35(8), 1031-1040 (2010-11-03) Immunohistochemical and serological characterization of membranous nephropathy in children and adolescents.Anne K Dettmar et al.Pediatric nephrology (Berlin, Germany), 33(3), 463-472 (2017-10-17) Biological evaluation of RBx-0128, a potent and selective dipeptidyl peptidase-IV inhibitor in type 2 diabetes genetic model.Joseph A Davis et al.Indian journal of pharmacology, 44(6), 759-764 (2012-12-19) Subcellular localization and interactions of Infectious Salmon Anemia Virus (ISAV) M1 and NEP as well as host Hsc70.Wenting Zhang et al.Virology journal, 14(1), 30-30 (2017-02-17) APP processing and metabolism in corneal fibroblasts and epithelium as a potential biomarker for Alzheimer's disease.Seung-Il Choi et al.Experimental eye research, 182, 167-174 (2019-04-02) Neprilysin levels at the acute phase of ST-elevation myocardial infarction.Hugo Bernelin et al.Clinical cardiology, 42(1), 32-38 (2018-10-05) HDAC3 negatively regulates spatial memory in a mouse model of Alzheimer's disease.Xiaolei Zhu et al.Aging cell, 16(5), 1073-1082 (2017-08-05) A novel method for determining the solubility of small molecules in aqueous media and polymer solvent systems using solution calorimetry.Hala M Fadda et al.Pharmaceutical research, 31(7), 1735-1743 (2014-02-21) Expression of neutral endopeptidase activity during clinical and experimental acute lung injury.Soshi Hashimoto et al.Respiratory research, 11, 164-164 (2010-12-01) Antifibrotic Effects of Amyloid-Beta and Its Loss in Cirrhotic Liver.Gayane Hrachia Buniatian et al.Cells, 9(2) (2020-02-25) Autocrine regulation of human sperm motility by tachykinins.Francisco M Pinto et al.Reproductive biology and endocrinology : RB&E, 8, 104-104 (2010-08-28) Hydrogen-rich water improves cognitive impairment gender-dependently in APP/PS1 mice without affecting Aβ clearance.Chen Hou et al.Free radical research, 52(11-12), 1311-1322 (2018-04-24) Alpha-Linolenic Acid from Perilla frutescens var. japonica Oil Protects Aβ-Induced Cognitive Impairment through Regulation of APP Processing and Aβ Degradation.Ah Young Lee et al.Journal of agricultural and food chemistry, 65(49), 10719-10729 (2017-11-03) Triptolide treatment reduces Alzheimer's disease (AD)-like pathology through inhibition of BACE1 in a transgenic mouse model of AD.Qi Wang et al.Disease models & mechanisms, 7(12), 1385-1395 (2014-12-07) Neuroprotective Effect of Alpha-Linolenic Acid against Aβ-Mediated Inflammatory Responses in C6 Glial Cell.Ah Young Lee et al.Journal of agricultural and food chemistry, 66(19), 4853-4861 (2018-04-19) Hyaluronidase 1 and hyaluronidase 2 are required for renal hyaluronan turnover.Vanessa Colombaro et al.Acta histochemica, 117(1), 83-91 (2014-12-04) TransCon CNP, a Sustained-Release C-Type Natriuretic Peptide Prodrug, a Potentially Safe and Efficacious New Therapeutic Modality for the Treatment of Comorbidities Associated with Fibroblast Growth Factor Receptor 3-Related Skeletal Dysplasias.Vibeke Miller Breinholt et al.The Journal of pharmacology and experimental therapeutics, 370(3), 459-471 (2019-06-27) Implementing school malaria surveys in Kenya: towards a national surveillance system.Caroline W Gitonga et al.Malaria journal, 9, 306-306 (2010-11-03) 2-Cl-MGV-1 Ameliorates Apoptosis in the Thalamus and Hippocampus and Cognitive Deficits After Cortical Infarct in Rats.Yicong Chen et al.Stroke, 48(12), 3366-3374 (2017-11-18) Intracranial injection of AAV expressing NEP but not IDE reduces amyloid pathology in APP+PS1 transgenic mice.Nikisha Carty et al.PloS one, 8(3), e59626-e59626 (2013-04-05) Identification and characterization of RSIY-11, a novel seminal peptide derived from semenogelin-1, which acts as a neutral endopeptidase inhibitor modulating sperm motility.Rani Fritz et al.Journal of assisted reproduction and genetics, 36(9), 1891-1900 (2019-07-28) Active site mutations change the cleavage specificity of neprilysin.Travis Sexton et al.PloS one, 7(2), e32343-e32343 (2012-03-03) C53: A novel particulate guanylyl cyclase B receptor activator that has sustained activity in vivo with anti-fibrotic actions in human cardiac and renal fibroblasts.Yang Chen et al.Journal of molecular and cellular cardiology, 130, 140-150 (2019-04-08) Chronic low dose of AM404 ameliorates the cognitive impairment and pathological features in hyperglycemic 3xTg-AD mice.Hei-Jen Huang et al.Psychopharmacology, 236(2), 763-773 (2018-11-15) Regional microglia are transcriptionally distinct but similarly exacerbate neurodegeneration in a culture model of Parkinson's disease.Eric Wildon Kostuk et al.Journal of neuroinflammation, 15(1), 139-139 (2018-05-13) The plastid-localized pfkB-type carbohydrate kinases FRUCTOKINASE-LIKE 1 and 2 are essential for growth and development of Arabidopsis thaliana.Jonathan Gilkerson et al.BMC plant biology, 12, 102-102 (2012-07-10) Metabolites of cerebellar neurons and hippocampal neurons play opposite roles in pathogenesis of Alzheimer's disease.Jing Du et al.PloS one, 4(5), e5530-e5530 (2009-05-14) 1-Substituted sialorphin analogues-synthesis, molecular modelling and in vitro effect on enkephalins degradation by NEP.Małgorzata Sobocińska et al.Amino acids, 51(8), 1201-1207 (2019-07-16) Improved learning and memory in aged mice deficient in amyloid beta-degrading neutral endopeptidase.Thomas Walther et al.PloS one, 4(2), e4590-e4590 (2009-02-26) Protection against vascular leak in neprilysin transgenic mice with complex overexpression pattern.Marilee J Wick et al.Transgenic research, 25(6), 773-784 (2016-07-03) Humulus japonicus inhibits the progression of Alzheimer's disease in a APP/PS1 transgenic mouse model.Tae-Shin Park et al.International journal of molecular medicine, 39(1), 21-30 (2016-12-23) Changes in the Factors Influencing Public Acceptance of Nuclear Power Generation in Japan Since the 2011 Fukushima Daiichi Nuclear Disaster.Norifumi Tsujikawa et al.Risk analysis : an official publication of the Society for Risk Analysis, 36(1), 98-113 (2015-08-01) Retrograde transport of masseter muscle-derived neprilysin to hippocampus.Takuya Kobayashi et al.Neuroscience letters, 698, 180-185 (2019-01-15) A selective p38α/β MAPK inhibitor alleviates neuropathology and cognitive impairment, and modulates microglia function in 5XFAD mouse.Min Sung Gee et al.Alzheimer's research & therapy, 12(1), 45-45 (2020-04-23) Deletion of tumor necrosis factor death receptor inhibits amyloid beta generation and prevents learning and memory deficits in Alzheimer's mice.Ping He et al.The Journal of cell biology, 178(5), 829-841 (2007-08-29) PLP/DM20 ratio is regulated by hnRNPH and F and a novel G-rich enhancer in oligodendrocytes.Erming Wang et al.Nucleic acids research, 35(12), 4164-4178 (2007-06-15) Long-term neprilysin gene transfer is associated with reduced levels of intracellular Abeta and behavioral improvement in APP transgenic mice.Brian Spencer et al.BMC neuroscience, 9, 109-109 (2008-11-19) Expression of neprilysin in periodontitis-affected gingival tissues.A Nezu et al.Archives of oral biology, 79, 35-41 (2017-03-13)

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