Melting point	114-115 ºC**
Density	1.184±0.06 g/cm3 (20 º

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Source	SDS/MSDS Samples
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Synthetic Route

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Articles

Peer-Reviewed Papers

Urodynamic effects of propiverine in children and adolescents with neurogenic bladder: results of a prospective long-term study.Heinrich Schulte-Baukloh et al.Journal of pediatric urology, 8(4), 386-392 (2011-09-13) [Additional effect of propiverine for naftopidil-resistant nocturia in the patient with benign prostate hypertrophy].Noritaka Kamimura et al.Hinyokika kiyo. Acta urologica Japonica, 57(2), 71-76 (2011-03-18) New strategies for medical management of overactive bladder in children.Annette Schröder et al.Current opinion in urology, 20(4), 313-317 (2011-04-09) Propiverine: a review of its use in the treatment of adults and children with overactive bladder associated with idiopathic or neurogenic detrusor overactivity, and in men with lower urinary tract symptoms.Kate McKeage Clinical drug investigation, 33(1), 71-91 (2013-01-05) Determination of propiverine hydrochloride in human plasma by high performance liquid chromatography-tandem mass spectrometry: application to the pharmacokinetic study of a sustained release formulation.Meihua Huang et al.Arzneimittel-Forschung, 61(9), 494-501 (2011-10-28) Pharmacokinetics and toxicity of antimuscarinic drugs for overactive bladder treatment in females.Umberto Leone Roberti Maggiore et al.Expert opinion on drug metabolism & toxicology, 8(11), 1387-1408 (2012-08-09) Responsiveness and minimal clinically important change in overactive bladder symptom score.Momokazu Gotoh et al.Urology, 78(4), 768-773 (2011-08-23) Efficacy, tolerability and safety profile of propiverine in the treatment of the overactive bladder (non-neurogenic and neurogenic)Madersbacher H, et al. World Journal of Urology, 19(5), 324-335 (2001) Effect of distigmine combined with propiverine on bladder activity in rats with spinal cord injury.Kimio Sugaya et al.International journal of urology : official journal of the Japanese Urological Association, 19(5), 480-483 (2012-01-10) Efficacy of propiverine, an anticholinergic agent, in young and old rats.Saori Nishijima et al.Life sciences, 89(13-14), 456-459 (2011-08-09) A new method for evaluating the bitterness of medicines in development using a taste sensor and a disintegration testing apparatus.Tsutomu Harada et al.Chemical & pharmaceutical bulletin, 58(8), 1009-1014 (2010-08-06) The influence of propiverine hydrochloride on cardiac repolarization in healthy women and cardiac male patients.F Donath et al.International journal of clinical pharmacology and therapeutics, 49(6), 353-365 (2011-05-27) [Combination therapy with anticholinergics and alpha-blockers for the treatment of overactive bladder in female patients--pilot study].J Krhut et al.Ceska gynekologie, 74(6), 416-420 (2011-01-21) The muscarinic receptor antagonist propiverine exhibits α(1)-adrenoceptor antagonism in human prostate and porcine trigonum.Melinda Wuest et al.World journal of urology, 29(2), 149-155 (2011-02-22) A placebo-controlled, multicentre study comparing the tolerability and eYcacy of propiverine and oxybutinin in patients with urgency and urge incontinence.Madersbacher H, et al. BJU International, 84, 646-651 (1999) Propiverine hydrochloride in Japanese patients with overactive bladder: a randomized, double-blind, placebo-controlled trial.Momokazu Gotoh et al.International journal of urology : official journal of the Japanese Urological Association, 18(5), 365-373 (2011-02-22) Oxybutynin and propiverine suppress adenosine triphosphate-induced bladder overactivity other than through antimuscarinic mechanisms.Hong Sang Moon et al.Urology, 76(2), 509-509 (2010-06-16) Urinary incontinence in children.Daniela Schultz-Lampel et al.Deutsches Arzteblatt international, 108(37), 613-620 (2011-10-07) Editorial comment from Dr Dmochowski to propiverine hydrochloride in Japanese patients with overactive bladder: a randomized, double-blind, placebo-controlled trial.Roger R Dmochowski International journal of urology : official journal of the Japanese Urological Association, 18(5), 374-374 (2011-03-02) Influence of a fat-rich meal on bioavailability of extended-release and immediate-release propiverine.Werner Siegmund et al.Journal of clinical pharmacology, 52(5), 681-690 (2011-05-10) Taste masking of propiverine hydrochloride by conversion to its free base.Tetsuo Ogata et al.Chemical & pharmaceutical bulletin, 60(8), 976-984 (2012-08-07) Correlation between improvements in Overactive Bladder Symptom Score and health-related quality of life questionnaires in overactive bladder patients treated with an antimuscarinic drug.Yasue Kubota et al.Neurourology and urodynamics, 30(7), 1309-1314 (2011-05-12) Editorial comment from Dr Sekido to propiverine hydrochloride in Japanese patients with overactive bladder: a randomized, double-blind, placebo-controlled trial.Noritoshi Sekido International journal of urology : official journal of the Japanese Urological Association, 18(5), 373-374 (2011-03-09) Excitatory effect of propiverine hydrochloride on urethral activity in rats.Katsumi Kadekawa et al.International journal of urology : official journal of the Japanese Urological Association, 19(6), 575-582 (2012-03-02) An overview on mixed action drugs for the treatment of overactive bladder and detrusor overactivity.A D Asimakopoulos et al.Urologia internationalis, 89(3), 259-269 (2012-07-11) Efficacy of propiverine ER with or without α-blockers related to maximum urinary flow rate in adult men with OAB: results of a 12-week, multicenter, non-interventional study.Matthias Oelke et al.World journal of urology, 29(2), 217-223 (2011-02-18)

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