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Platycodigenin | CAS:22327-82-8
Platycodigenin
  • Name:Platycodigenin
  • CAS:22327-82-8
  • Synonyms:2beta,3beta,16beta,23,24-pentahydroxy-olean-12-en-28-oic acid
  • Molecular Formula:C30H48O7
  • Molecular Weight:520.70
  • EINESC:

Description

Properties

Melting point 242-243 ºC**
Density 1.28±0.1 g/cm3 (20 ºC

Safety

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SDS

Source SDS/MSDS Samples
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Synthetic Route
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Articles
Peer-Reviewed Papers
The enzymic hydrolysis and synthesis of acetylcholine.D NACHMANSOHN et al.Advances in enzymology and related subjects of biochemistry, 12, 259-339 (1951-01-01) Acute effects of Anabaena spiroides extract and paraoxon-methyl on freshwater cladocerans from tropical and temperate regions: links between the ChE activity and survival and its implications for tropical ecotoxicological studies.Emanuela Cristina Freitas et al.Aquatic toxicology (Amsterdam, Netherlands), 146, 105-114 (2013-12-03) Cholinesterase and carboxylesterase inhibition in Planorbarius corneus exposed to binary mixtures of azinphos-methyl and chlorpyrifos.Luis Claudio Cacciatore et al.Aquatic toxicology (Amsterdam, Netherlands), 128-129, 124-134 (2013-01-08) Effect of hypoxanthine, antioxidants and allopurinol on cholinesterase activities in rats.Morgahna Nathalie Wamser et al.Journal of neural transmission (Vienna, Austria : 1996), 120(9), 1359-1367 (2013-02-13) Bioelectronic sniffer for nicotine using enzyme inhibition.Kohji Mitsubayashi et al.Analytica chimica acta, 573-574, 69-74 (2007-08-29) Reversible effect of maternal exposure to chlorpyrifos on the intermediate granule cell progenitors in the hippocampal dentate gyrus of rat offspring.Takumi Ohishi et al.Reproductive toxicology (Elmsford, N.Y.), 35, 125-136 (2012-10-27) Recovery of residual curarization after red blood cell transfusion.Veit-Simon Eckle et al.Medical science monitor : international medical journal of experimental and clinical research, 18(11), CS91-CS93 (2012-11-01) Ectoenzymes and cholinesterase activity and biomarkers of oxidative stress in patients with lung cancer.Daniela Zanini et al.Molecular and cellular biochemistry, 374(1-2), 137-148 (2012-11-28) The role of serum cholinesterase activity and S100B protein in the evaluation of organophosphate poisoning.T Yardan et al.Human & experimental toxicology, 32(10), 1081-1088 (2013-02-21) Cholinesterase confabs and cousins: approaching forty years.Palmer Taylor et al.Chemico-biological interactions, 203(1), 10-13 (2012-10-23) Esterases in the milk and blood plasma of swine. I. Substrate specificity and electrophoresis studies.K B AUGUSTINSSON et al.The Biochemical journal, 71(3), 477-484 (1959-03-01) Toxicokinetics of Chemical Warfare Agents: Nerve Agents and Vesicants Handbook of Toxicology of Chemical Warfare Agents, 755-790 (2009) The Leu-Arg-Glu (LRE) adhesion motif in proteins of the neuromuscular junction with special reference to proteins of the carboxylesterase/cholinesterase family.Glynis Johnson et al.Comparative biochemistry and physiology. Part D, Genomics & proteomics, 8(3), 231-243 (2013-07-16) A four-step approach to evaluate mixtures for consistency with dose addition.Richard C Hertzberg et al.Toxicology, 313(2-3), 134-144 (2012-11-14) This special Issue of Chemico-Biological Interactions comprises 70 manuscripts from lectures and short talks given at the 11th International Meeting on Cholinesterases. Preface.Sofya Lushchekina et al.Chemico-biological interactions, 203(1), 1-2 (2013-04-06) Preparation, characterization of Fe3O4 at TiO2 magnetic nanoparticles and their application for immunoassay of biomarker of exposure to organophosphorus pesticides.Xiao Zhang et al.Biosensors & bioelectronics, 41, 669-674 (2012-11-06) Liver function in workers exposed of the cosmetics industry.T Casale et al.Annali di igiene : medicina preventiva e di comunita, 25(6), 519-527 (2013-11-29) Use of cholinesterase activity as a biomarker of pesticide exposure used on Costa Rican banana plantations in the native tropical fish Astyanax aeneus (Günther, 1860).F Mena et al.Journal of environmental biology, 35(1), 35-42 (2014-03-04) Synthesis, characterization, and SAR of arylated indenoquinoline-based cholinesterase and carbonic anhydrase inhibitors.Makbule Ekiz et al.Archiv der Pharmazie, 351(9), e1800167-e1800167 (2018-08-07) Characterization of plasma cholinesterase in rabbit and evaluation of the inhibitory potential of diazinon.Ana Lourdes Oropesa et al.Ecotoxicology and environmental safety, 100, 39-43 (2014-01-18) Cholinesterases and neurotoxicity as highly sensitive biomarkers for an organophosphate insecticide in a freshwater gastropod (Chilina gibbosa) with low sensitivity carboxylesterases.Karina Bianco et al.Aquatic toxicology (Amsterdam, Netherlands), 144-145, 26-35 (2013-10-22) The progress in the cholinesterase quantification methods.Ondrej Holas et al.Expert opinion on drug discovery, 7(12), 1207-1223 (2012-09-28) Regional inhibition of cholinesterase in free-ranging western pond turtles (Emys marmorata) occupying California mountain streams.Erik Meyer et al.Environmental toxicology and chemistry, 32(3), 692-698 (2013-01-24) Responses of B-esterase enzymes in oysters (Crassostrea gigas) transplanted to pesticide contaminated bays form the Ebro Delta (NE, Spain).Victoria Ochoa et al.Marine pollution bulletin, 66(1-2), 135-142 (2012-11-22) Screening for cholinesterase inhibitors in selected fruits and vegetables.Szwajgier D and Borowiec K Biotechnology, 15(2) (2012) The Arabidopsis thaliana ortholog of a purported maize cholinesterase gene encodes a GDSL-lipase.Mrinalini Muralidharan et al.Plant molecular biology, 81(6), 565-576 (2013-02-23) Inhibition of cholinesterase and monoamine oxidase-B activity by Tacrine-Homoisoflavonoid hybrids.Yang Sun et al.Bioorganic & medicinal chemistry, 21(23), 7406-7417 (2013-10-17) Tetramerization domain of human butyrylcholinesterase is at the C-terminus.R M Blong et al.The Biochemical journal, 327 ( Pt 3), 747-757 (1998-05-15) Population-scale genomics-Enabling precision public health Advances in Genetics, 103, 119-161 (2019) Determinants of intracellular pH in the erythrocyte.J Warth et al.British journal of haematology, 29(3), 369-372 (1975-03-01) Temperature: a prolonged confounding factor on cholinesterase activity in the tropical reef fish Acanthochromis polyacanthus.Emmanuelle S Botté et al.Aquatic toxicology (Amsterdam, Netherlands), 140-141, 337-339 (2013-07-31) Microcalorimetric study of the inhibition of butyrylcholinesterase by paraoxonDebord, J., et al. Analytical Chemistry, 389, 97-101 (2009) Novel cholinesterase modulators and their ability to interact with DNA.Jana Janockova et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 115, 364-369 (2013-07-16) Population-scale genomics-Enabling precision public health Advances in Genetics, 103, 119-161 (2019) Amygdala projections to the lateral bed nucleus of the stria terminalis in the macaque: comparison with ventral striatal afferents.Danielle M deCampo et al.The Journal of comparative neurology, 521(14), 3191-3216 (2013-05-23) Characterization of cholinesterases in the damselfish Sergeant major (Abudefduf saxatilis).Gabriela Rodríguez-Fuentes et al.Ecotoxicology and environmental safety, 96, 99-102 (2013-07-28) Anticholinesterase activity of selected phenolic acids and flavonoids - interaction testing in model solutions.Dominik Szwajgier Annals of agricultural and environmental medicine : AAEM, 22(4), 690-694 (2015-12-29) Low-dose sarin exposure produces long term changes in brain neurochemistry of mice.Dhawal P Oswal et al.Neurochemical research, 38(1), 108-116 (2012-10-12) Select small core structure carbamates exhibit high contact toxicity to "carbamate-resistant" strain malaria mosquitoes, Anopheles gambiae (Akron).Dawn M Wong et al.PloS one, 7(10), e46712-e46712 (2012-10-11) 1,3-substituted imidazolidine-2,4,5-triones: synthesis and inhibition of cholinergic enzymes.Vladimir Pejchal et al.Molecules (Basel, Switzerland), 16(9), 7565-7582 (2011-09-07) Indole alkaloids of Psychotria as multifunctional cholinesterases and monoamine oxidases inhibitors.Carolina S Passos et al.Phytochemistry, 86, 8-20 (2012-12-25) Studies on cholinesterase: 4. Purification of pseudo-cholinesterase from horse serum.F Strelitz The Biochemical journal, 38(1), 86-88 (1944-01-01) Neospora caninum: Activity of cholinesterases during the acute and chronic phases of an experimental infection in gerbils.Alexandre A Tonin et al.Experimental parasitology, 135(4), 669-674 (2013-10-22) Patient information sheet for plasma cholinesterase deficiency.D Dillon et al.Anaesthesia, 68(10), 1085-1085 (2013-09-21) Determinants of intracellular pH in the erythrocyte.J Warth et al.British journal of haematology, 29(3), 369-372 (1975-03-01) Environmental hazards of pesticides from pineapple crop production in the Río Jiménez watershed (Caribbean Coast, Costa Rica).S Echeverría-Sáenz et al.The Science of the total environment, 440, 106-114 (2012-10-09) The significance of low substrate concentration measurements for mechanistic interpretation in cholinesterases.Jure Stojan Chemico-biological interactions, 203(1), 44-50 (2013-01-03) Oxidative stress and cholinesterase inhibition in plasma, erythrocyte and brain of rats' pups following lactational exposure to malathion.Slimen Selmi et al.Environmental toxicology and pharmacology, 34(3), 753-760 (2012-11-06) Cholinesterases of the tissues and sera of rabbits.G B KOELLE The Biochemical journal, 53(2), 217-226 (1953-01-01) Pesticide exposure on sloths (Bradypus variegatus and Choloepus hoffmanni) in an agricultural landscape of Northeastern Costa Rica.Margaret Verónica Pinnock Branford et al.Journal of environmental biology, 35(1), 29-34 (2014-03-04) QSAR, docking, dynamic simulation and quantum mechanics studies to explore the recognition properties of cholinesterase binding sites.J Correa-Basurto et al.Chemico-biological interactions, 209, 1-13 (2013-12-11) Transcriptomic and phylogenetic analysis of Culex pipiens quinquefasciatus for three detoxification gene families.Liangzhen Yan et al.BMC genomics, 13, 609-609 (2012-11-13) Research on cholinesterases in the Soviet Union and Russia: a historical perspective.Eugene V Rozengart et al.Chemico-biological interactions, 203(1), 3-9 (2013-03-15) An expedient, ionic liquid mediated multi-component synthesis of novel piperidone grafted cholinesterase enzymes inhibitors and their molecular modeling study.Alireza Basiri et al.European journal of medicinal chemistry, 67, 221-229 (2013-07-23) A secondary isotope effect study of equine serum butyrylcholinesterase-catalyzed hydrolysis of acetylthiocholine.Kenneth L Wiley et al.Chemico-biological interactions, 187(1-3), 124-127 (2010-05-25) Effect of the Biphenyl Neolignan Honokiol on AβSrinivas Kantham et al.ACS chemical neuroscience, 8(9), 1901-1912 (2017-06-27) Characterization of plasma cholinesterase from the White stork (Ciconia ciconia) and its in vitro inhibition by anticholinesterase pesticides.Ana-Lourdes Oropesa et al.Ecotoxicology and environmental safety, 97, 131-138 (2013-08-22) Characterization of cholinesterases in Chironomus riparius and the effects of three herbicides on chlorpyrifos toxicity.Joanne Pérez et al.Aquatic toxicology (Amsterdam, Netherlands), 144-145, 296-302 (2013-11-12) Assessment of pesticide exposure in female population living in cotton growing areas of Punjab, Pakistan.Seema Tahir et al.Bulletin of environmental contamination and toxicology, 89(6), 1138-1141 (2012-10-16) Chlorpyrifos is associated with slower serum cholinesterase recovery in acute organophosphate-poisoned patients.C H Chaou et al.Clinical toxicology (Philadelphia, Pa.), 51(5), 402-408 (2013-04-18) Temperature: a prolonged confounding factor on cholinesterase activity in the tropical reef fish Acanthochromis polyacanthus.Emmanuelle S Botté et al.Aquatic toxicology (Amsterdam, Netherlands), 140-141, 337-339 (2013-07-31) Paraoxonase activity and genetic polymorphisms in northern Han Chinese workers exposed to organophosphate pesticides.Xiaofeng Zhang et al.Experimental biology and medicine (Maywood, N.J.), 239(2), 232-239 (2013-12-12) [To the 80-anniversary of cholinesterase. The cholinesterase club in Sechenov Institute of Evolutionary Physiology and Biochemistry].E V Rozengart et al.Zhurnal evoliutsionnoi biokhimii i fiziologii, 48(6), 537-541 (2013-02-14) Microcalorimetric study of the inhibition of butyrylcholinesterase by paraoxonDebord, J., et al. Analytical Chemistry, 389, 97-101 (2009) Novel cholinesterase modulators and their ability to interact with DNA.Jana Janockova et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 115, 364-369 (2013-07-16)
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