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DL-alpha-Methyltyrosine | CAS:658-48-0
DL-alpha-Methyltyrosine
  • Name:DL-alpha-Methyltyrosine
  • CAS:658-48-0
  • Synonyms:
  • Molecular Formula:C10H13NO3
  • Molecular Weight:195.21
  • EINESC:211-523-0

Description

Properties

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Safety

SDS/MSDS S22;S24/25

SDS

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Peer-Reviewed Papers
S-nitrosoglutathione covalently modifies cysteine residues of human carbonyl reductase 1 and affects its activity.Tereza Hartmanová et al.Chemico-biological interactions, 202(1-3), 136-145 (2013-01-09) Global analysis of serine-threonine protein kinase genes in Neurospora crassa.Gyungsoon Park et al.Eukaryotic cell, 10(11), 1553-1564 (2011-10-04) Structures of the PutA peripheral membrane flavoenzyme reveal a dynamic substrate-channeling tunnel and the quinone-binding site.Harkewal Singh et al.Proceedings of the National Academy of Sciences of the United States of America, 111(9), 3389-3394 (2014-02-20) Vitamin K4 induces tumor cytotoxicity in human prostate carcinoma PC-3 cells via the mitochondria-related apoptotic pathway.Yu Jiang et al.Die Pharmazie, 68(6), 442-448 (2013-07-24) A biophysical approach to menadione membrane interactions: relevance for menadione-induced mitochondria dysfunction and related deleterious/therapeutic effects.João P Monteiro et al.Biochimica et biophysica acta, 1828(8), 1899-1908 (2013-04-18) Menadione (vitamin K3) is a catabolic product of oral phylloquinone (vitamin K1) in the intestine and a circulating precursor of tissue menaquinone-4 (vitamin K2) in rats.Yoshihisa Hirota et al.The Journal of biological chemistry, 288(46), 33071-33080 (2013-10-03) Farnesol misplaces tip-localized Rho proteins and inhibits cell wall integrity signalling in Aspergillus fumigatus.Karl Dichtl et al.Molecular microbiology, 76(5), 1191-1204 (2010-04-20) Oxidation resistance 1 is essential for protection against oxidative stress and participates in the regulation of aging in Caenorhabditis elegans.Y Sanada et al.Free radical research, 48(8), 919-928 (2014-05-29) Superoxide dismutases and glutaredoxins have a distinct role in the response of Candida albicans to oxidative stress generated by the chemical compounds menadione and diamide.Guilherme Maranhão Chaves et al.Memorias do Instituto Oswaldo Cruz, 107(8), 998-1005 (2013-01-09) Menadione.Ghada S Hassan Profiles of drug substances, excipients, and related methodology, 38, 227-313 (2013-05-15) Angiotensin II protects primary rat hepatocytes against bile salt-induced apoptosis.Golnar Karimian et al.PloS one, 7(12), e52647-e52647 (2013-01-10) Intracellular forms of menadione-dependent small-colony variants of methicillin-resistant Staphylococcus aureus are hypersusceptible to β-lactams in a THP-1 cell model due to cooperation between vacuolar acidic pH and oxidant species.Laetitia G Garcia et al.The Journal of antimicrobial chemotherapy, 67(12), 2873-2881 (2012-09-25) Determination of menadione sodium hydrogen sulphite and nicotinamide in multivitamin formulations by high-performance liquid chromatography.N Sadlej-Sosnowska et al.Journal of chromatography, 357(1), 227-232 (1986-04-23) Novel insights into the antiproliferative effects and synergism of quercetin and menadione in human leukemia Jurkat T cells.Irina Baran et al.Leukemia research, 38(7), 836-849 (2014-05-28) [The role of thiol antioxidants in restoring mitochondrial functions, modified by microbial metabolites].N I Fedotcheva et al.Biofizika, 57(5), 820-826 (2012-11-10) The histone methyltransferase G9a regulates tolerance to oxidative stress-induced energy consumption.Human Riahi et al.PLoS biology, 17(3), e2006146-e2006146 (2019-03-13) A non-classical LysR-type transcriptional regulator PA2206 is required for an effective oxidative stress response in Pseudomonas aeruginosa.F Jerry Reen et al.PloS one, 8(1), e54479-e54479 (2013-02-06) Glutathione maintenance mitigates age-related susceptibility to redox cycling agents.Nicholas O Thomas et al.Redox biology, 10, 45-52 (2016-10-01) Activation of PINK1-Parkin-Mediated Mitophagy Degrades Mitochondrial Quality Control Proteins in Fuchs Endothelial Corneal Dystrophy.Takashi Miyai et al.The American journal of pathology, 189(10), 2061-2076 (2019-07-31) Rapid Bioassay-Guided Isolation of Antibacterial Clerodane Type Diterpenoid from Dodonaea viscosa (L.) Jaeq.Muhammad Khurram et al.International journal of molecular sciences, 16(9), 20290-20307 (2015-09-08) On methods for the detection of reactive oxygen species generation by human spermatozoa: analysis of the cellular responses to catechol oestrogen, lipid aldehyde, menadione and arachidonic acid.R J Aitken et al.Andrology, 1(2), 192-205 (2013-01-15) Toxicity of CuO nanoparticles to yeast Saccharomyces cerevisiae BY4741 wild-type and its nine isogenic single-gene deletion mutants.Kaja Kasemets et al.Chemical research in toxicology, 26(3), 356-367 (2013-01-24) Activation of a PGC-1-related coactivator (PRC)-dependent inflammatory stress program linked to apoptosis and premature senescence.Natalie Gleyzer et al.The Journal of biological chemistry, 288(12), 8004-8015 (2013-02-01) In silico and in vitro characterization of anti-amyloidogenic activity of vitamin K3 analogues for Alzheimer's disease.Pham Dinh Quoc Huy et al.Biochimica et biophysica acta, 1830(4), 2960-2969 (2013-01-09) Experimental resistance to drug combinations in Leishmania donovani: metabolic and phenotypic adaptations.Maya Berg et al.Antimicrobial agents and chemotherapy, 59(4), 2242-2255 (2015-02-04) Systems analysis of methylerythritol-phosphate pathway flux in E. coli: insights into the role of oxidative stress and the validity of lycopene as an isoprenoid reporter metabolite.Mareike Bongers et al.Microbial cell factories, 14, 193-193 (2015-11-28) Into the depths: Techniques for in vitro three-dimensional microtissue visualizationKabadi PK, et al. Biotechniques, 59(5), 279-286 (2015) Global analysis of serine/threonine and tyrosine protein phosphatase catalytic subunit genes in Neurospora crassa reveals interplay between phosphatases and the p38 mitogen-activated protein kinase.Arit Ghosh et al.G3 (Bethesda, Md.), 4(2), 349-365 (2013-12-19) Novel phosphorylation and ubiquitination sites regulate reactive oxygen species-dependent degradation of anti-apoptotic c-FLIP protein.Rachel P Wilkie-Grantham et al.The Journal of biological chemistry, 288(18), 12777-12790 (2013-03-23) Momordica charantia polysaccharides could protect against cerebral ischemia/reperfusion injury through inhibiting oxidative stress mediated c-Jun N-terminal kinase 3 signaling pathway.Juanjuan Gong et al.Neuropharmacology, 91, 123-134 (2014-12-17) Into the depths: Techniques for in vitro three-dimensional microtissue visualization.Pranita K Kabadi et al.BioTechniques, 59(5), 279-286 (2015-11-12) Simvastatin improves mitochondrial respiration in peripheral blood cells.Jon Ambæk Durhuus et al.Scientific reports, 10(1), 17012-17012 (2020-10-14) Proteome changes associated with Leishmania donovani promastigote adaptation to oxidative and nitrosative stresses.Abul Hasan Sardar et al.Journal of proteomics, 81, 185-199 (2013-02-05) Momordica charantia polysaccharides could protect against cerebral ischemia/reperfusion injury through inhibiting oxidative stress mediated c-Jun N-terminal kinase 3 signaling pathwayGong J, et al. Neuropharmacology, 9, 123-134 (2015) Menadione sodium bisulphite (MSB): Beyond seed-soaking. Root pretreatment with MSB primes salt stress tolerance in tomato plantsJimenez-Arias D, et al. Environmental and Experimental Botany, 157, 161-170 (2019) CR108, a novel vitamin K3 derivative induces apoptosis and breast tumor inhibition by reactive oxygen species and mitochondrial dysfunction.Chun-Ru Yang et al.Toxicology and applied pharmacology, 273(3), 611-622 (2013-10-17) Lysosome dysfunction enhances oxidative stress-induced apoptosis through ubiquitinated protein accumulation in Hela cells.Chunyan Yu et al.Anatomical record (Hoboken, N.J. : 2007), 296(1), 31-39 (2012-11-06) A built-in adjuvant-engineered mucosal vaccine against dysbiotic periodontal diseases.Sao Puth et al.Mucosal immunology, 12(2), 565-579 (2018-11-30) Cytotoxic activity of vitamins K1, K2 and K3 against human oral tumor cell lines.H Okayasu et al.Anticancer research, 21(4A), 2387-2392 (2001-11-29) Effects of low-dose ionizing radiation and menadione, an inducer of oxidative stress, alone and in combination in a vertebrate embryo model.Catherine L Bladen et al.Radiation research, 178(5), 499-503 (2012-10-25) Ciona intestinalis NADH dehydrogenase NDX confers stress-resistance and extended lifespan on Drosophila.Dmytro V Gospodaryov et al.Biochimica et biophysica acta, 1837(11), 1861-1869 (2014-08-16) Pyrrole alkaloids with potential cancer chemopreventive activity isolated from a goji berry-contaminated commercial sample of African mango.Jie Li et al.Journal of agricultural and food chemistry, 62(22), 5054-5060 (2014-05-06) Vitamins K interact with N-terminus α-synuclein and modulate the protein fibrillization in vitro. Exploring the interaction between quinones and α-synuclein.Fernanda Luna da Silva et al.Neurochemistry international, 62(1), 103-112 (2012-10-16) Identification of point mutations in clinical Staphylococcus aureus strains that produce small-colony variants auxotrophic for menadione.Melissa A Dean et al.Infection and immunity, 82(4), 1600-1605 (2014-01-24) Bioelectrochemical probing of intracellular redox processes in living yeast cells--application of redox polymer wiring in a microfluidic environment.Arto Heiskanen et al.Analytical and bioanalytical chemistry, 405(11), 3847-3858 (2013-02-02) Cytoprotection of human endothelial cells from oxidant stress with CDDO derivatives: network analysis of genes responsible for cytoprotection.James A Bynum et al.Pharmacology, 95(3-4), 181-192 (2015-05-01) Alpha-tocopheryl succinate inhibits autophagic survival of prostate cancer cells induced by vitamin K3 and ascorbate to trigger cell death.Marco Tomasetti et al.PloS one, 7(12), e52263-e52263 (2012-12-29) Screening test for rapid food safety evaluation by menadione-catalysed chemiluminescent assay.Shiro Yamashoji et al.Food chemistry, 138(4), 2146-2151 (2013-03-19) Genome-wide association for sensitivity to chronic oxidative stress in Drosophila melanogaster.Katherine W Jordan et al.PloS one, 7(6), e38722-e38722 (2012-06-21) Antimutagenic and antioxidant properties of plumbagin and other naphthoquinones.Sanjeev Kumar et al.Mutation research, 755(1), 30-41 (2013-05-22) Menadione and ethacrynic acid inhibit the hypoxia-inducible factor (HIF) pathway by disrupting HIF-1α interaction with p300.Yu-Ran Na et al.Biochemical and biophysical research communications, 434(4), 879-884 (2013-04-27) Specific dietary carbohydrates differentially influence the life span and fecundity of Drosophila melanogaster.Oleh V Lushchak et al.The journals of gerontology. Series A, Biological sciences and medical sciences, 69(1), 3-12 (2013-06-01) Expression of Paracoccidioides brasiliensis AMY1 in a Histoplasma capsulatum amy1 mutant, relates an α-(1,4)-amylase to cell wall α-(1,3)-glucan synthesis.Emma Camacho et al.PloS one, 7(11), e50201-e50201 (2012-11-28) 2-Methyl-1,4-naphthoquinone, vitamin K(3), decreases gap-junctional intercellular communication via activation of the epidermal growth factor receptor/extracellular signal-regulated kinase cascade.Lars-Oliver Klotz et al.Cancer research, 62(17), 4922-4928 (2002-09-05) Continuous flow-extractive desorption electrospray ionization: analysis from "non-electrospray ionization-friendly" solvents and related mechanism.Li Li et al.Analytica chimica acta, 769, 84-90 (2013-03-19) MicroRNAs differentially regulate carbonyl reductase 1 (CBR1) gene expression dependent on the allele status of the common polymorphic variant rs9024.James L Kalabus et al.PloS one, 7(11), e48622-e48622 (2012-11-08) A family of glutathione peroxidases contributes to oxidative stress resistance in Candida albicans.Pedro Miramón et al.Medical mycology, 52(3), 223-239 (2014-03-15)
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