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Peer-Reviewed Papers

New FDA-Approved Disease-Modifying Therapies for Multiple Sclerosis.Clayton English et al.Clinical therapeutics, 37(4), 691-715 (2015-04-08) Screening Immunomodulators To Skew the Antigen-Specific Autoimmune Response.Laura Northrup et al.Molecular pharmaceutics, 14(1), 66-80 (2017-01-04) Carbonic anhydrase inhibitors. Identification of selective inhibitors of the human mitochondrial isozymes VA and VB over the cytosolic isozymes I and II from a natural product-based phenolic library.Rohan A Davis et al.Bioorganic & medicinal chemistry, 18(1), 14-18 (2009-12-08) Fumarate analogs act as allosteric inhibitors of the human mitochondrial NAD(P)+-dependent malic enzyme.Ju-Yi Hsieh et al.PloS one, 9(6), e98385-e98385 (2014-06-10) Modification of chitosan with monomethyl fumaric acid in an ionic liquid solution.Wang Z, et al. Carbohydrate Polymers, 117, 973-979 (2015) Structure-activity relationships of trans-substituted-propenoic acid derivatives on the nicotinic acid receptor HCA2 (GPR109A).J P D van Veldhoven et al.Bioorganic & medicinal chemistry letters, 21(9), 2736-2739 (2010-12-21) Altered Oligodendrocyte Maturation and Myelin Maintenance: The Role of Antiretrovirals in HIV-Associated Neurocognitive Disorders.Brigid K Jensen et al.Journal of neuropathology and experimental neurology, 74(11), 1093-1118 (2015-10-16) Dimethyl Fumarate Disrupts Human Innate Immune Signaling by Targeting the IRAK4-MyD88 Complex.Balyn W Zaro et al.Journal of immunology (Baltimore, Md. : 1950), 202(9), 2737-2746 (2019-03-20) Computational repositioning of dimethyl fumarate for treating alcoholic liver disease.Ye Zhang et al.Cell death & disease, 11(8), 641-641 (2020-08-20) A selective inhibitor and probe of the cellular functions of Jumonji C domain-containing histone demethylases.Luo X, et al. Journal of the American Chemical Society, 133(24), 9451-9456 (2011) A concise synthesis of (?)-methoxyfumimycin ethyl ester.Zhou Z, et al. J. Chem. Res. (M), 38(6) (2014) Impact of Minocycline on Extracellular Matrix Metalloproteinase Inducer, a Factor Implicated in Multiple Sclerosis Immunopathogenesis.Jennifer N Hahn et al.Journal of immunology (Baltimore, Md. : 1950), 197(10), 3850-3860 (2016-10-14) A chemoproteomic portrait of the oncometabolite fumarate.Rhushikesh A Kulkarni et al.Nature chemical biology, 15(4), 391-400 (2019-02-06) Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway.Xin Xie et al.British journal of pharmacology, 172(15), 3929-3943 (2015-05-09) Isolation and structure elucidation of the new fungal metabolite (−)-xylariamide A.Davis R A, et al. Journal of Natural Products, 68(5), 769-772 (2005)

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