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Peer-Reviewed Papers

Short communication: Activating stimuli enhance immunotoxin-mediated killing of HIV-infected macrophages.Matthew D Marsden et al.AIDS research and human retroviruses, 24(11), 1399-1404 (2008-11-13) Flow cytometric analysis of drug-induced HIV-1 transcriptional activity in A2 and A72 J-Lat cell linesDaniela B and Melanie O Bio-protocol, 7(10) (2017) The BET bromodomain inhibitor JQ1 activates HIV latency through antagonizing Brd4 inhibition of Tat-transactivation.Zichong Li et al.Nucleic acids research, 41(1), 277-287 (2012-10-23) Mechanisms of HIV receptor and co-receptor down-regulation by prostratin: role of conventional and novel PKC isoforms.Marjan Hezareh et al.Antiviral chemistry & chemotherapy, 15(4), 207-222 (2004-10-02) Prostratin induces HIV activation and downregulates HIV receptors in peripheral blood lymphocytes.Joaquín Rullas et al.Antiviral therapy, 9(4), 545-554 (2004-10-01) Prostratin antagonizes HIV latency by activating NF-kappaB.Samuel A Williams et al.The Journal of biological chemistry, 279(40), 42008-42017 (2004-07-31) Prostratin exhibits both replication enhancing and inhibiting effects on FIV infection of feline CD4+ T-cells.Chi Ngai Chan et al.Virus research, 171(1), 121-128 (2012-12-04) High-frequency epigenetic repression and silencing of retroviruses can be antagonized by histone deacetylase inhibitors and transcriptional activators, but uniform reactivation in cell clones is restricted by additional mechanisms.Richard A Katz et al.Journal of virology, 81(6), 2592-2604 (2007-01-05) Epigenetic regulation of HIV-1 transcription.Manoj Kumar Tripathy et al.Epigenomics, 3(4), 487-502 (2011-12-01) Effects of prostratin on Cyclin T1/P-TEFb function and the gene expression profile in primary resting CD4+ T cells.Tzu-Ling Sung et al.Retrovirology, 3, 66-66 (2006-10-04) The protein kinase C agonist prostratin induces differentiation of human myeloid leukemia cells and enhances cellular differentiation by chemotherapeutic agents.Xing Shen et al.Cancer letters, 356(2 Pt B), 686-696 (2014-12-03) Potent and Targeted Activation of Latent HIV-1 Using the CRISPR/dCas9 Activator Complex.Sheena M Saayman et al.Molecular therapy : the journal of the American Society of Gene Therapy, 24(3), 488-498 (2015-11-20) HIV type 1 inhibition by protein kinase C modulatory compounds.David Warrilow et al.AIDS research and human retroviruses, 22(9), 854-864 (2006-09-23) Giving Samoan healers credit for prostratin.Paul Alan Cox et al.Science (New York, N.Y.), 320(5883), 1589-1589 (2008-06-21) De novo assembly of Euphorbia fischeriana root transcriptome identifies prostratin pathway related genes.Roberto A Barrero et al.BMC genomics, 12, 600-600 (2011-12-14) Variability in content of the anti-AIDS drug candidate prostratin in Samoan populations of Homalanthus nutans.Holly E Johnson et al.Journal of natural products, 71(12), 2041-2044 (2008-11-15) Reactivation of latent HIV-1 by inhibition of BRD4.Jian Zhu et al.Cell reports, 2(4), 807-816 (2012-10-09) Bioactive components in the fruits of Ziziphus jujuba Mill. against the inflammatory irritant action of Euphorbia plants.L Yu et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 19(3-4), 239-244 (2011-10-11) Designed, synthetically accessible bryostatin analogues potently induce activation of latent HIV reservoirs in vitro.Brian A DeChristopher et al.Nature chemistry, 4(9), 705-710 (2012-08-24) Sulfonation pathway inhibitors block reactivation of latent HIV-1.Jeffrey P Murry et al.Virology, 471-473, 1-12 (2014-10-14) Selective histonedeacetylase inhibitor M344 intervenes in HIV-1 latency through increasing histone acetylation and activation of NF-kappaB.Hao Ying et al.PloS one, 7(11), e48832-e48832 (2012-11-21) Prostratin and 12-O-tetradecanoylphorbol 13-acetate are potent and selective inhibitors of Chikungunya virus replication.Mélanie Bourjot et al.Journal of natural products, 75(12), 2183-2187 (2012-12-12) Dual role of prostratin in inhibition of infection and reactivation of human immunodeficiency virus from latency in primary blood lymphocytes and lymphoid tissue.Angélique Biancotto et al.Journal of virology, 78(19), 10507-10515 (2004-09-16) Prostratin and bortezomib are novel inducers of latent Kaposi's sarcoma-associated herpesvirus.Helen J Brown et al.Antiviral therapy, 10(6), 745-751 (2005-10-13) Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection.Sophie Reuse et al.PloS one, 4(6), e6093-e6093 (2009-07-01) Characterization of Inducible Transcription and Translation-Competent HIV-1 Using the RNAscope ISH Technology at a Single-Cell Resolution.Wang Zhang et al.Frontiers in microbiology, 9, 2358-2358 (2018-10-20) Prostratin as a new therapeutic agent targeting HIV viral reservoirs.Marjan Hezareh Drug news & perspectives, 18(8), 496-500 (2006-01-05) Histone deacetylase inhibitor Scriptaid reactivates latent HIV-1 promoter by inducing histone modification in in vitro latency cell lines.Hao Ying et al.International journal of molecular medicine, 26(2), 265-272 (2010-07-03) Comparative characteristic of the inflammatory diterpenes in the roots of Euphorbia fischeriana with different preparation method using HPLC-ELSD.Yuping Tang et al.Fitoterapia, 83(3), 427-433 (2012-01-24) IFI44 suppresses HIV-1 LTR promoter activity and facilitates its latency.Derek Power et al.Virology, 481, 142-150 (2015-03-18)

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