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1-Chloro-2,2-dimethylpropane | CAS:753-89-9
1-Chloro-2,2-dimethylpropane
  • Name:1-Chloro-2,2-dimethylpropane
  • CAS:753-89-9
  • Synonyms:(Chloromethyl)trimethylmethane; 2,2-Dimethylpropyl chloride; Neopentyl chloride
  • Molecular Formula:C5H11Cl
  • Molecular Weight:106.59
  • EINESC:212-040-8

Description

Properties

Melting point -20 ºC***
Boiling point 84.3 ºC****
Flash point -8.9±0.0 ºC, 计算值*
Density 0.8659 g/cm3 (20 ºC)**
Refractive index 1.4048 (589.3 nm 20 ºC)****

Safety

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SDS

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Articles
Peer-Reviewed Papers
Midterm outcome of risedronate therapy for patients with Paget's disease of bone in the central part of Japan.Yoshihiro Nishida et al.Clinical rheumatology, 32(2), 241-245 (2012-11-10) Low-dose risedronate sodium protects bone cells after abrupt oestrogen withdrawal.G Wang et al.The Journal of international medical research, 40(5), 1761-1774 (2012-12-05) Treatment of postmenopausal osteoporosis with delayed-release risedronate 35 mg weekly for 2 years.M R McClung et al.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 24(1), 301-310 (2012-10-20) How rebates, copayments, and administration costs affect the cost-effectiveness of osteoporosis therapies.Nicole C Ferko et al.Managed care (Langhorne, Pa.), 21(11), 44-52 (2012-12-15) How rebates, copayments, and administration costs affect the cost-effectiveness of osteoporosis therapies.Nicole C Ferko et al.Managed care (Langhorne, Pa.), 21(11), 44-52 (2012-12-15) Comparison of Three Endodontic Irrigant Regimens against Dual-Species Interkingdom Biofilms: Considerations for Maintaining the Status Quo.Om Alkhir Alshanta et al.Antibiotics (Basel, Switzerland), 9(9) (2020-09-26) Etidronic acid: a new and efficient catalyst for the synthesis of novel 5-nitro-3, 4-dihydropyrimidin-2 (1H)-onesSavant MM, et al. Catalysis Letters, 132(1-2), 281-284 (2009) A novel automated hydrophilic interaction liquid chromatography method using diode-array detector/electrospray ionization tandem mass spectrometry for analysis of sodium risedronate and related degradation products in pharmaceuticals.Tiziana Bertolini et al.Journal of chromatography. A, 1365, 131-139 (2014-09-23) Facile conversion of epoxides to thiiranes with ammonium thiocyanate catalyzed with etidronic acidWu L, et al. Bulletin of the Korean Chemical Society,, 31(5), 1419-1420 (2010) Effects of various squalene epoxides on coenzyme Q and cholesterol synthesis.Magnus Bentinger et al.Biochimica et biophysica acta, 1841(7), 977-986 (2014-04-22) The role of risedronate in osteopenia in Crohn's disease.Alice Buchan et al.Gut, 64(1), 185-185 (2013-12-07) [Bisphosphonate related osteonecrosis of the jaw and infection with Actinomyces].J Alberto Arranz Caso et al.Medicina clinica, 139(15), 676-680 (2012-10-30) Stable carbon isotope analysis of polyphosphonate complexing agents by anion chromatography coupled to isotope ratio mass spectrometry: method development and application.Philipp R Martin et al.Analytical and bioanalytical chemistry, 412(20), 4827-4835 (2019-12-10) Occurrence and transformation of phosphonates in textile dyeing wastewater along full-scale combined treatment processes.Shu Wang et al.Water research, 184, 116173-116173 (2020-07-28) Transcriptional and metabolic response against hydroxyethane-(1,1-bisphosphonic acid) on bacterial denitrification by a halophilic Pannonibacter sp. strain DN.Rashmi Koju et al.Chemosphere, 252, 126478-126478 (2020-03-21) [Ocular myasthenia revealed by risedronate].P A Sanchez-Ayaso et al.Revista de neurologia, 55(10), 639-640 (2012-11-13) An IC-MS/MS Method for the Determination of 1-Hydroxyethylidene-1,1-diphosphonic Acid on Uncooked Foods Treated with Peracetic Acid-Based Sanitizers.Ippei Suzuki et al.Chemical & pharmaceutical bulletin, 64(12), 1713-1719 (2016-12-03) Risk of atypical femoral fracture during and after bisphosphonate use.Jörg Schilcher et al.Acta orthopaedica, 86(1), 100-107 (2015-01-15) Oral bisphosphonates: early endosseous dental implant success and crestal bone changes. A retrospective study.Sayma Memon et al.The International journal of oral & maxillofacial implants, 27(5), 1216-1222 (2012-10-12) Atorvastatin, etidronate, or both in patients at high risk for atherosclerotic aortic plaques: a randomized, controlled trial.Tetsuya Kawahara et al.Circulation, 127(23), 2327-2335 (2013-05-10) Disrupting antibiotic resistance propagation by inhibiting the conjugative DNA relaxase.Scott A Lujan et al.Proceedings of the National Academy of Sciences of the United States of America, 104(30), 12282-12287 (2007-07-17) Application of 1-hydroxyethylidene-1, 1-diphosphonic acid in boiler water for industrial boilers.Bin Zeng et al.Water science and technology : a journal of the International Association on Water Pollution Research, 67(7), 1544-1550 (2013-04-05) Effect of optimized three-component antiscalant mixture on calcium carbonate scale deposition.Zhanhui Shen et al.Water science and technology : a journal of the International Association on Water Pollution Research, 75(2), 255-262 (2017-01-24) The requirement for calcification differs between ecologically important coccolithophore species.Charlotte E Walker et al.The New phytologist, 220(1), 147-162 (2018-06-20) Cost-effectiveness of denosumab in the treatment of postmenopausal osteoporosis in Canada.D Chau et al.Journal of medical economics, 15 Suppl 1, 3-14 (2012-10-06) In vivo phosphoantigen levels in bisphosphonate-treated human breast tumors trigger Vγ9Vδ2 T-cell antitumor cytotoxicity through ICAM-1 engagement.Ismahène Benzaïd et al.Clinical cancer research : an official journal of the American Association for Cancer Research, 18(22), 6249-6259 (2012-10-04) In vitro assessment of cobalt oxide particle dissolution in simulated lung fluids for identification of new decorporating agents.Anne Van Der Meeren et al.Toxicology in vitro : an international journal published in association with BIBRA, 66, 104863-104863 (2020-04-19) Uptake of gold (III) from waste gold solution onto biomass-based adsorbents organophosphonic acid functionalized spent buckwheat hulls.Ping Yin et al.Bioresource technology, 128, 36-43 (2012-12-01) Changes in bone mineral density at 3 years in postmenopausal women receiving anastrozole and risedronate in the IBIS-II bone substudy: an international, double-blind, randomised, placebo-controlled trial.Ivana Sestak et al.The Lancet. Oncology, 15(13), 1460-1468 (2014-12-03) The effects of risedronate administered in combination with a proton pump inhibitor for the treatment of osteoporosis.Soichiro Itoh et al.Journal of bone and mineral metabolism, 31(2), 206-211 (2012-11-10) Effect of dentine conditioning with phytic acid or etidronic acid on growth factor release, dental pulp stem cell migration and viability.D Deniz Sungur et al.International endodontic journal, 52(6), 838-846 (2018-12-27) Actinide-contaminated Skin: Comparing Decontamination Efficacy of Water, Cleansing Gels, and DTPA Gels.A Tazrart et al.Health physics, 115(1), 12-20 (2018-05-23) A meta-analysis characterizing the dose-response relationships for three oral nitrogen-containing bisphosphonates in postmenopausal women.J Yates Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 24(1), 253-262 (2012-10-27) Etidronic acid. A review of its pharmacological properties and therapeutic efficacy in resorptive bone disease.C J Dunn et al.Drugs & aging, 5(6), 446-474 (1994-12-01) Farsenyl pyrophosphate synthase is a potential molecular drug target of risedronate in Babesia bovis.Akio Ueno et al.Parasitology international, 62(2), 189-192 (2013-01-02) Squamous metaplasia of the conjunctiva: a previously unrecognized adverse effect of risedronate sodium.Ivayla I Geneva et al.JAMA ophthalmology, 131(2), 249-251 (2013-02-16) FDA-approved drug labeling for the study of drug-induced liver injury.Minjun Chen et al.Drug discovery today, 16(15-16), 697-703 (2011-06-01) Fourier transform infrared imaging as a tool to chemically and spatially characterize matrix-mineral deposition in osteoblasts.Meghan E Faillace et al.Calcified tissue international, 92(1), 50-58 (2012-11-13) Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).Zhichao Liu et al.PLoS computational biology, 7(12), e1002310-e1002310 (2011-12-24) Batch studies of phosphonate adsorption on granular ferric hydroxides.T Reinhardt et al.Water science and technology : a journal of the International Association on Water Pollution Research, 81(1), 10-20 (2020-04-16) Effects of bisphosphonate treatment on circulating osteogenic endothelial progenitor cells in postmenopausal women.Pilar Peris et al.Mayo Clinic proceedings, 88(1), 46-55 (2012-12-12) Improvement in bone properties by using risedronate adsorbed hydroxyapatite novel nanoparticle based formulation in a rat model of osteoporosis.H Sahana et al.Journal of biomedical nanotechnology, 9(2), 193-201 (2013-05-01) Risedronate increases osteoblastic differentiation and function through connexin43.Hyung Min Jeong et al.Biochemical and biophysical research communications, 432(1), 152-156 (2013-02-05) Randomized, double-blinded, placebo-controlled, trial of risedronate for the prevention of bone mineral density loss in nonmetastatic prostate cancer patients receiving radiation therapy plus androgen deprivation therapy.Richard Choo et al.International journal of radiation oncology, biology, physics, 85(5), 1239-1245 (2012-12-26) Osteomalacia in a patient with Paget's bone disease treated with long-term etidronate.E Hoppé et al.Morphologie : bulletin de l'Association des anatomistes, 96(313), 40-43 (2012-10-02) Biosorption of heavy metal ions onto agricultural residues buckwheat hulls functionalized with 1-hydroxylethylidenediphosphonic acid.Ping Yin et al.Journal of agricultural and food chemistry, 60(47), 11664-11674 (2012-11-01) [Combination of alendronate plus alfacalcidol in the treatment of osteoporosis. Rationale, preclinical data and clinical evidence].E Von Schacht et al.MMW Fortschritte der Medizin, 154 Suppl 1, 10-21 (2013-02-23) Development of bone seeker radiopharmaceuticals by Scandium-47 and estimation of human absorbed dose.Leila Deilami-Nezhad et al.Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 129, 108-116 (2017-08-27) A novel monthly dosing regimen of risedronate for the treatment of postmenopausal osteoporosis: 2-year data.Michael R McClung et al.Calcified tissue international, 92(1), 59-67 (2012-11-15) Effect on bone turnover markers of once-yearly intravenous infusion of zoledronic acid versus daily oral risedronate in patients treated with glucocorticoids.Jean-Pierre Devogelaer et al.Rheumatology (Oxford, England), 52(6), 1058-1069 (2013-02-01) UV/chlorine oxidation of the phosphonate antiscalant 1-Hydroxyethane-1, 1-diphosphonic acid (HEDP) used for reverse osmosis processes: Organic phosphorus removal and scale inhibition properties changes.Nan Huang et al.Journal of environmental management, 237, 180-186 (2019-02-21) Marija Mirković et al.Materials science & engineering. C, Materials for biological applications, 102, 124-133 (2019-05-31)Novel theranostic nanoplatform is expected to integrate imaging for guiding and monitoring of the tumor therapy with great therapeutic efficacy and fewer side effects. Here we describe the preparation of a multifunctional 99mTc-bisphosphonate-coated magnetic nanoparticles (MNPs) based on Fe3O4 and...
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