Melting point	64-67 ºC

Symbol(GHS)	Xn;N
Hazard Codes	R22;R51/53
SDS/MSDS	S61

Source	SDS/MSDS Samples
Alfa-Aesar	View & Download
Sigma-Aldrich	View & Download
TCI	View & Download

Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

Revised structure and synthesis of celastramycin a, a potent innate immune suppressor.Kikuchi H, et al. Organic Letters, 11(8), 1693-1695 (2009) Randomised, double-blind, placebo-controlled study of a single dose of an amylmetacresol/2,4-dichlorobenzyl alcohol plus lidocaine lozenge or a hexylresorcinol lozenge for the treatment of acute sore throat due to upper respiratory tract infection.Damien McNally et al.Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 15(2), 281-294 (2012-05-15) Comparative stability-indicating chromatographic methods for determination of 4-hexylresorcinol in pharmaceutical formulation and shrimps.Rafeek F Shokry et al.Journal of pharmaceutical and biomedical analysis, 145, 386-398 (2017-07-19) [Long-term preservation of DNA in aqueous solutions in the presence of the chemical analogues of microbial autoregulators].O K Davydova et al.Mikrobiologiia, 75(5), 662-669 (2006-11-10) Resorcinol-sn-glycerol derivatives: novel 2-arachidonoylglycerol mimetics endowed with high affinity and selectivity for cannabinoid type 1 receptor.Brizzi A, et al. Journal of Medicinal Chemistry, 54(24), 8278-8288 (2011) Comparison of the simple cyclic voltammetry (CV) and DPPH assays for the determination of antioxidant capacity of active principles.Jesús F Arteaga et al.Molecules (Basel, Switzerland), 17(5), 5126-5138 (2012-05-05) 4-Hexylresorcinol inhibits transglutaminase-2 activity and has synergistic effects along with cisplatin in KB cells.Seong-Gon Kim et al.Oncology reports, 25(6), 1597-1602 (2011-03-23) [Modification of bacterial population structure on anti-lysozyme activity under the influence of hexylresorcinol].O V Bukharin et al.Zhurnal mikrobiologii, epidemiologii, i immunobiologii, (6)(6), 7-10 (2009-02-04) Preparation of tyrosinase inhibitors and antibrowning agents using green technology.Xue Dong et al.Food chemistry, 197(Pt A), 589-596 (2015-12-01) [Determination of 4-hexylresorcinol residues in prawns and crabs].Mitsuo Nakazato et al.Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan, 46(6), 282-285 (2006-01-31) Translational isomerizations in [2] catenanes with unsymmetrically substituted resorcinol-based tethers.Halterman R L and Martyn D E The Journal of Organic Chemistry, 72(21), 7841-7848 (2007) Browning prevention by ascorbic acid and 4-hexylresorcinol: different mechanisms of action on polyphenol oxidase in the presence and in the absence of substrates.E Arias et al.Journal of food science, 72(9), C464-C470 (2007-11-24) Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.Naomi L Kruhlak et al.Toxicology mechanisms and methods, 18(2-3), 217-227 (2008-01-01) Preparation, characterization, and preliminary antibrowning evaluations of norartocarpetin microemulsions.Zong-Ping Zheng et al.Journal of agricultural and food chemistry, 63(5), 1615-1621 (2015-01-21) 4-hexylresorcinol exerts antitumor effects via suppression of calcium oscillation and its antitumor effects are inhibited by calcium channel blockers.Seong-Gon Kim et al.Oncology reports, 29(5), 1835-1840 (2013-02-22) Solvent effects on the spectroscopic properties of 4-hexylresorcinol.Sonia Patricia Olivares et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 71(2), 336-339 (2008-02-20) [Effect of a synthetic analogue of bacterial anabiosis autoinducers hexylresorcinol on the stability of membrane structures].N G Loĭlo et al.Prikladnaia biokhimiia i mikrobiologiia, 45(2), 181-187 (2009-04-23) Effect of pyrophosphate and 4-hexylresorcinol pretreatment on quality of refrigerated white shrimp (Litopenaeus vannamei) kept under modified atmosphere packaging.R Thepnuan et al.Journal of food science, 73(3), S124-S133 (2008-04-05) Adsorptive Stripping Voltammetric Determination of 4-Hexylresorcinol in Pharmaceutical Products Using Multiwalled Carbon Nanotube Based Electrodes.Kachoosangi RT, et al. Electroanalysis, 20(15), 1714-1718 (2008) Application of a novel microtitre plate-based assay for the discovery of new inhibitors of DNA gyrase and DNA topoisomerase VI.James A Taylor et al.PloS one, 8(2), e58010-e58010 (2013-03-08) A measurement of the unstirred aqueous boundary layer in a Franz diffusion cell.Matthew Alexander Miller et al.Pharmaceutical development and technology, 17(6), 705-711 (2011-05-11) Cobalt(II) complexation with small biomolecules as studied by 57Co emission Mössbauer spectroscopy.Alexander A Kamnev et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 172, 77-82 (2016-05-01) [A comparative study of the inducing effect of homoserine lactone and hexylresorcinol on phenotypic dissociation in bacteria].A B Margulis et al.Mikrobiologiia, 75(4), 468-471 (2006-10-10) 4-hexylresorcinol inhibits NF-κB phosphorylation and has a synergistic effect with cisplatin in KB cells.Seong-Gon Kim et al.Oncology reports, 26(6), 1527-1532 (2011-08-30) Ascorbic acid and 4-hexylresorcinol effects on pear PPO and PPO catalyzed browning reaction.E Arias et al.Journal of food science, 72(8), C422-C429 (2007-11-13) Determination of 4-Hexylresorcinol in Shrimp Samples by Solid Phase Extraction Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry.Yunbin Hao et al.Molecules (Basel, Switzerland), 23(9) (2018-08-31) Topical antiseptics for the treatment of sore throat block voltage-gated neuronal sodium channels in a local anaesthetic-like manner.Vanessa Buchholz et al.Naunyn-Schmiedeberg's archives of pharmacology, 380(2), 161-168 (2009-04-16) Tyrosinase-Catalyzed Hydroxylation of 4-Hexylresorcinol, an Antibrowning and Depigmenting Agent: A Kinetic Study.Carmen Vanessa Ortiz-Ruiz et al.Journal of agricultural and food chemistry, 63(31), 7032-7040 (2015-07-16) Distribution and Characteristics of Polyphenoloxidase from Pacific White Shrimp (Litopenaeus vannamei).Thanasak Sae-Leaw et al.Journal of food science, 84(5), 1078-1086 (2019-04-09) Effects of 4-hexylresorcinol on the phenoloxidase from Hyphantria cunea (Lepidoptera: Arctiidae): In vivo and in vitro studies.Mahboobeh Sharifi et al.Insect science, 22(5), 639-650 (2014-07-06) Structure-Activity Relationships of Thiazolyl Resorcinols, Potent and Selective Inhibitors of Human Tyrosinase.Tobias Mann et al.International journal of molecular sciences, 19(3) (2018-03-03) [Induction of the NO synthesis in lactobacilli under stress conditions].O A Smolentseva et al.Molekuliarnaia genetika, mikrobiologiia i virusologiia, (1)(1), 25-29 (2012-06-19) Effects of known phenoloxidase inhibitors on hemocyanin-derived phenoloxidase from Limulus polyphemus.Jamie Wright et al.Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 163(3-4), 303-308 (2012-08-14) PEG-immobilization of cardol and soluble polymer-supported synthesis of some cardol-coumarin derivatives: preliminary evaluation of their inhibitory activity on mushroom tyrosinase.Graziella Tocco et al.Bioorganic & medicinal chemistry letters, 19(1), 36-39 (2008-12-05) Rapid autographic method for detection of enzymatic browning inhibitors based on enzyme immobilization.Oscar B Micheloni et al.Food chemistry, 269, 638-643 (2018-08-14) [Influence of chemical analogues of microbial autoregulators on the sensitivity of DNA to UV radiation].O K Davydova et al.Mikrobiologiia, 75(5), 654-661 (2006-11-10) 4-Hexylresorcinol, a Potent Inhibitor of Mushroom Tyrosinase.DAWLEY RM and FLURKEY WH. Journal of Food Science, 58(3), 609-610 (1993) Cisplatin and 4-hexylresorcinol synergise to decrease metastasis and increase survival rate in an oral mucosal melanoma xenograft model: a preliminary study.Sang-Woon Lee et al.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 34(3), 1595-1603 (2013-02-16) In vitro anthelmintic activity of Melia azedarach naturalized in Argentina.Víctor D Szewczuk et al.Phytotherapy research : PTR, 20(11), 993-996 (2006-08-31) [Effect of chemical chaperones on properties of lysozyme and the reaction center protein from Rhodobacter sphaeroides].Iu F Krupianskiĭ et al.Biofizika, 56(1), 13-30 (2011-03-30) 4-hexylresorcinol stimulates the differentiation of SCC-9 cells through the suppression of E2F2, E2F3 and Sp3 expression and the promotion of Sp1 expression.Seong-Gon Kim et al.Oncology reports, 28(2), 677-681 (2012-06-06) Preparation of steppogenin and ascorbic acid, vitamin E, butylated hydroxytoluene oil-in-water microemulsions: Characterization, stability, and antibrowning effects for fresh apple juice.Jing Tao et al.Food chemistry, 224, 11-18 (2017-02-06) Aerosol deposition of hydroxyapatite and 4-hexylresorcinol coatings on titanium alloys for dental implants.Seong-Gon Kim et al.Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 69(11), e354-e363 (2011-08-09) [Non-species-specific effects of unacylated homoserine lactone and hexylresorcinol, low molecular weight autoregulators, on the growth and development of bacteria].A L Muliukin et al.Mikrobiologiia, 75(4), 472-482 (2006-10-10)

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