Melting point	207-210 ºC

Symbol(GHS)	Xi
Hazard Codes	R36/37/38
SDS/MSDS	S26;S37/39

Source	SDS/MSDS Samples
Alfa-Aesar	View & Download
Sigma-Aldrich	View & Download
TCI	View & Download

Synthetic Route

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Name	CAS
Levobunolol hydrochloride	27912-14-7	View

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Articles

Peer-Reviewed Papers

A fluorometric assay for biotinidase.H Ebrahim et al.Analytical biochemistry, 154(1), 282-286 (1986-04-01) Environmental metabolite, 1,2-diacetylbenzene, produces cytotoxicity through ROS generation in HUVEC cells.Min Kyeong Kim et al.Journal of toxicology and environmental health. Part A, 70(15-16), 1336-1343 (2007-07-27) A new murine model of giant proximal axonopathy.D D Tshala-Katumbay et al.Acta neuropathologica, 109(4), 405-410 (2005-03-11) Organic solvent metabolite, 1,2-diacetylbenzene, impairs neural progenitor cells and hippocampal neurogenesis.Min-Sun Kim et al.Chemico-biological interactions, 194(2-3), 139-147 (2011-10-25) Probing mechanisms of axonopathy. Part I: Protein targets of 1,2-diacetylbenzene, the neurotoxic metabolite of aromatic solvent 1,2-diethylbenzene.Desire Tshala-Katumbay et al.Toxicological sciences : an official journal of the Society of Toxicology, 105(1), 134-141 (2008-05-27) New insights into mechanisms of gamma-diketone-induced axonopathy.Desire Tshala-Katumbay et al.Neurochemical research, 34(11), 1919-1923 (2009-05-01) Cytotoxicity of 1,2-diacetylbenzene in human neuroblastoma SHSY5Y cells is mediated by oxidative stress.Min-Sun Kim et al.Toxicology, 243(1-2), 216-223 (2007-12-08) Possible involvement of 1,2-diacetylbenzene in diethylbenzene-induced neuropathy in rats.F Gagnaire et al.Journal of applied toxicology : JAT, 11(4), 261-268 (1991-08-01) Probing mechanisms of axonopathy. Part II: Protein targets of 2,5-hexanedione, the neurotoxic metabolite of the aliphatic solvent n-hexane.Desire Tshala-Katumbay et al.Toxicological sciences : an official journal of the Society of Toxicology, 107(2), 482-489 (2008-11-27) A liquid chromatographic-mass spectrometric method to evaluate the distribution kinetics of 1,2-diethylbenzene and its metabolite 1,2-diacetylbenzene in the F344 male rat.Karla D Thrall et al.Journal of toxicology and environmental health. Part A, 70(1), 67-72 (2006-12-13) Amino acid and protein targets of 1,2-diacetylbenzene, a potent aromatic gamma-diketone that induces proximal neurofilamentous axonopathy.Min-Sun Kim et al.Toxicology and applied pharmacology, 183(1), 55-65 (2002-09-10) Theoretical determination of chromophores in the chromogenic effects of aromatic neurotoxicants.Chang-Guo Zhan et al.Journal of the American Chemical Society, 124(11), 2744-2752 (2002-03-14) Protein Engineering of a Pyridoxal-5'-Phosphate-Dependent l-Aspartate-α-Decarboxylase from Tribolium castaneum for β-Alanine Production.Xin-Jun Yu et al.Molecules (Basel, Switzerland), 25(6) (2020-03-18) Axonopathy-inducing 1,2-diacetylbenzene forms adducts with motor and cytoskeletal proteins required for axonal transport.Mohammad I Sabri et al.Neurochemical research, 32(12), 2152-2159 (2007-06-20) Alteration of brainstem auditory evoked potentials in diethylbenzene and diacetylbenzene-treated rats.F Gagnaire et al.Journal of applied toxicology : JAT, 12(5), 343-350 (1992-10-01) 1,2-diacetylbenzene, the neurotoxic metabolite of a chromogenic aromatic solvent, induces proximal axonopathy.M S Kim et al.Toxicology and applied pharmacology, 177(2), 121-131 (2001-12-13)

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