Melting point	120.5-121 ºC (acetic acid )
Density	1.373±0.06 g/cm3 (20 º

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Source	SDS/MSDS Samples
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Articles

Peer-Reviewed Papers

The pharmacological activity of some new fluorescent small molecule histamine H2 receptor (H2-R) ligands, derived from aminopotentidine and squaramide, in the GTPase assay.Georgiana Petrache et al.Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi, 114(1), 255-259 (2010-06-01) Synthesis, spectral properties, and detection limits of reactive squaraine dyes, a new class of diode laser compatible fluorescent protein labelsOswald et al.Bioconjugate chemistry, 11(3), 438-438 (2000-05-23) The complexation of a novel squaric bis(thiosemicarbazone); 3,4-bis{[(aminothioxomethyl)amino]azamethylene}cyclobut-ene-1,2-diol.H S Seleem et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 78(3), 1097-1104 (2011-01-18) One-pot squaric acid diester mediated aqueous protein conjugation.Frederik Wurm et al.Chemical communications (Cambridge, England), 49(71), 7815-7817 (2013-07-26) Carbonyl groups as molecular valves to regulate chloride binding to squaramides.Vijayakumar Ramalingam et al.Organic letters, 10(15), 3315-3318 (2008-07-02) Squaric acid monoamide mannosides as ligands for the bacterial lectin FimH: covalent inhibition or not?Carsten Grabosch et al.Chembiochem : a European journal of chemical biology, 12(7), 1066-1074 (2011-04-08) Synthesis of a 200-member library of squaric acid N-hydroxylamide amides.Julie Charton et al.Bioorganic & medicinal chemistry letters, 18(18), 4968-4971 (2008-09-02) Squaric acids: a new motif for designing inhibitors of protein tyrosine phosphatases.Jian Xie et al.Organic letters, 6(1), 83-86 (2004-01-03) Temperature- and pressure-induced proton transfer in the 1:1 adduct formed between squaric acid and 4,4'-bipyridine.David M S Martins et al.Journal of the American Chemical Society, 131(11), 3884-3893 (2009-03-04) Evaluation of the inhibitory potential of five squaric acid derivatives against pancreatic lipase.Zorka Bobcheva et al.Journal of enzyme inhibition and medicinal chemistry, 26(4), 587-591 (2011-03-29) Identification and SAR of squarate inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2).Frank Lovering et al.Bioorganic & medicinal chemistry, 17(9), 3342-3351 (2009-04-15) New and unusual scaffolds in medicinal chemistry.Charles M Marson Chemical Society reviews, 40(11), 5514-5533 (2011-08-13) Asymmetric iodolactonization utilizing chiral squaramides.Jørn E Tungen et al.Organic letters, 14(23), 5884-5887 (2012-11-15) Tetrahedron Letters, 48, 3595-3595 (2007) Capturing hydrolysis products in the solid state: effects of pH on uranyl squarates under ambient conditions.Clare E Rowland et al.Inorganic chemistry, 49(19), 8668-8673 (2010-03-13) Squaramides: physical properties, synthesis and applications.R Ian Storer et al.Chemical Society reviews, 40(5), 2330-2346 (2011-03-15) Squaramide-tertiary amine catalyzed asymmetric cascade sulfa-Michael/Michael addition via dynamic kinetic resolution: access to highly functionalized chromans with three contiguous stereocenters.Wen Yang et al.Organic letters, 15(6), 1190-1193 (2013-03-08) Strategies for optimizing the performance of carbazole thiophene appended unsymmetrical squaraine dyes for dye-sensitized solar cells.Suraj Soman et al.Physical chemistry chemical physics : PCCP, 17(35), 23095-23103 (2015-08-19) Construction of a 3D array of cadmium (ii) using squarate as a building block.Maji, Tapas Kumar, et al. CrystEngComm, 155-158 (2001) Water-driven ligations using cyclic amino squarates: a class of useful SN1-like reactions.Dawei Cui et al.Chemical communications (Cambridge, England), 47(4), 1348-1350 (2010-11-18) Squaric acid mediated chemoselective PEGylation of proteins: reactivity of single-step-activated α-amino poly(ethylene glycol)s.Carsten Dingels et al.Chemistry (Weinheim an der Bergstrasse, Germany), 18(52), 16828-16835 (2012-11-09) An application of polymer-enhanced capillary transient isotachophoresis with an emissive boronic acid functionalized squarylium dye as an on-capillary labeling agent for gram-positive bacteria.Shingo Saito et al.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 29(1), 157-159 (2013-01-11) A fluorescence high throughput screening method for the detection of reactive electrophiles as potential skin sensitizers.Cristina Avonto et al.Toxicology and applied pharmacology, 289(2), 177-184 (2015-10-13) Role of the substituent effect over the squarate oxocarbonic ring: spectroscopy, crystal structure, and density functional theory calculations of 1,2-dianilinosquairane.Carlos E Silva et al.The journal of physical chemistry. A, 114(37), 10097-10109 (2010-08-26) Crystal structures and spectroscopic properties of ester amide and diamide of squaric acid with prolinamide.Tsonko Kolev et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 72(3), 502-509 (2008-12-23) Heterocycles, 35, 1149-1149 (1993) Chiral squaramide derivatives are excellent hydrogen bond donor catalysts.Jeremiah P Malerich et al.Journal of the American Chemical Society, 130(44), 14416-14417 (2008-10-14) The binding site of zinc and indium metal to amino acid derivatized squarate complexes - Implications in inhibitor and mediator designs.Natasha Ramroop-Singh et al.Bioorganic chemistry, 38(5), 234-241 (2010-07-06) Creation of hydrogen bonded 1D networks by co-crystallization of N,N'-bis(2-pyridyl)aryldiamines with dicarboxylic acids.Igor Bensemann et al.Organic & biomolecular chemistry, 1(8), 1425-1434 (2003-08-22) The expanded pharmacological profile of histamine H2 receptor (H2R) species isoforms with respect to the interaction with new squaramide H2R ligands, in the GTP-ASE assay.Georgiana Petrache et al.Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi, 113(3), 915-920 (2010-03-03) Structural and spectroscopic elucidation of tetrapetide glycyl-(L)-prolyl-glycyl-glycine and its hydrogensquarate.Tsonko M Kolev Protein and peptide letters, 15(7), 713-718 (2008-09-11) Squaramide-based reagent for selective chromogenic sensing of Cu(II) through a zwitterion radical.Elena Sanna et al.Organic letters, 12(17), 3840-3843 (2010-08-10) Squaric acid-based peptidic inhibitors of matrix metalloprotease-1.M Burak Onaran et al.The Journal of organic chemistry, 70(26), 10792-10802 (2005-12-17) 2-(Phenylethyl)ammonium hydrogensquarate hemihydrate: crystal structure, solid-state IR-spectroscopic and theoretical characterization.Bojidarka B Ivanova et al.Amino acids, 39(1), 309-314 (2010-01-19) Squarylium-based chromogenic anion sensors.Eun-Mi Lee et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 95, 25-28 (2012-05-23)

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