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Symbol(GHS)	Xn
Hazard Codes	R63
SDS/MSDS	S36/37

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Peer-Reviewed Papers

Genetic alterations in chromosome 10q24.3 and glutathione S-transferase omega 2 gene polymorphism in ovarian cancer.W Pongstaporn et al.Journal of experimental & clinical cancer research : CR, 25(1), 107-114 (2006-06-10) Comparison of functional antagonism between isoproterenol and M2 muscarinic receptors in guinea pig ileum and trachea.R S Ostrom et al.The Journal of pharmacology and experimental therapeutics, 288(3), 969-976 (1999-02-23) Conversion of N-(2-chloroethyl)-4-piperidinyl diphenylacetate (4-DAMP mustard) to an aziridinium ion and its interaction with muscarinic receptors in various tissues.E A Thomas et al.Molecular pharmacology, 41(4), 718-726 (1992-04-01) The quaternary transformation products of N-(3-chloropropyl)-4-piperidinyl diphenylacetate and N-(2-chloroethyl)-4-piperidinyl diphenylacetate (4-DAMP mustard) have differential affinity for subtypes of the muscarinic receptor.F J Ehlert et al.The Journal of pharmacology and experimental therapeutics, 276(2), 405-410 (1996-02-01) Muscarinic M2 receptor-mediated contraction in the guinea pig Taenia caeci: possible involvement of protein kinase C.A Shen et al.Biochemical pharmacology, 56(11), 1529-1537 (1998-11-25) Kinetics of activation and in vivo muscarinic receptor binding of N-(2-bromoethyl)-4-piperidinyl diphenylacetate: an analog of 4-DAMP mustard.M T Griffin et al.The Journal of pharmacology and experimental therapeutics, 266(1), 301-305 (1993-07-01) Role and mechanisms of action of acetylcholine in the regulation of rat cholangiocyte secretory functions.D Alvaro et al.The Journal of clinical investigation, 100(6), 1349-1362 (1997-09-18) M2 muscarinic receptors inhibit forskolin- but not isoproterenol-mediated relaxation in bovine tracheal smooth muscle.R S Ostrom et al.The Journal of pharmacology and experimental therapeutics, 286(1), 234-242 (1998-07-10) The M2 muscarinic receptor mediates contraction through indirect mechanisms in mouse urinary bladder.Frederick J Ehlert et al.The Journal of pharmacology and experimental therapeutics, 313(1), 368-378 (2004-12-21) Selective inactivation of muscarinic M2 and M3 receptors in guinea-pig ileum and atria in vitro.R M Eglen et al.British journal of pharmacology, 109(4), 946-952 (1993-08-01) The small co-chaperone p23 overexpressing transgenic mouse.Junli Zhang et al.Journal of neuroscience methods, 212(2), 190-194 (2012-10-02) N-terminal modification of VEGF-A C terminus-derived peptides delineates structural features involved in neuropilin-1 binding and functional activity.Haiyan Jia et al.Chembiochem : a European journal of chemical biology, 15(8), 1161-1170 (2014-04-29) GSTA1, GSTO1 and GSTO2 gene polymorphisms in Italian asthma patients.Renato Polimanti et al.Clinical and experimental pharmacology & physiology, 37(8), 870-872 (2010-04-09) Functional polymorphisms of GSTA1 and GSTO2 genes associated with asthma in Italian children.Sara Piacentini et al.Clinical chemistry and laboratory medicine, 50(2), 311-315 (2011-11-02) Collagen IV-derived peptide binds hydrophobic cavity of Legionella pneumophila Mip and interferes with bacterial epithelial transmigration.Can Ünal et al.Cellular microbiology, 13(10), 1558-1572 (2011-07-29) Biochemical characterization of recombinant methionine aminopeptidases (MAPs) from Mycobacterium tuberculosis H37Rv.Sai Shyam Narayanan et al.Molecular and cellular biochemistry, 365(1-2), 191-202 (2012-04-03) GSTO2*N142D gene polymorphism associated with hypothyroidism in Italian patients.Sara Piacentini et al.Molecular biology reports, 40(2), 1967-1971 (2012-10-20) The effect of muscarinic receptor alkylation on endothelium-dependent vasodilation in SHR.M G Hendriks et al.Blood pressure, 2(4), 332-338 (1993-12-01) Functional role for the M2 muscarinic receptor in smooth muscle of guinea pig ileum.E A Thomas et al.Molecular pharmacology, 44(1), 102-110 (1993-07-01) The guinea pig ileum lacks the direct, high-potency, M(2)-muscarinic, contractile mechanism characteristic of the mouse ileum.Michael T Griffin et al.Naunyn-Schmiedeberg's archives of pharmacology, 380(4), 327-335 (2009-07-08) Role of muscarinic M2 and M3 receptors in guinea-pig trachea: effects of receptor alkylation.N Watson et al.European journal of pharmacology, 278(3), 195-201 (1995-05-24) Functional role of muscarinic M(2) receptors in alpha,beta-methylene ATP induced, neurogenic contractions in guinea-pig ileum.G W Sawyer et al.British journal of pharmacology, 129(7), 1458-1464 (2000-04-01) Acetylcholine-induced desensitization of the contractile response to histamine in Guinea pig ileum is prevented by either pertussis toxin treatment or by selective inactivation of muscarinic M(3) receptors.D Shehnaz et al.The Journal of pharmacology and experimental therapeutics, 297(3), 1152-1159 (2001-05-18) Muscarinic M3 receptor inactivation reveals a pertussis toxin-sensitive contractile response in the guinea pig colon: evidence for M2/M3 receptor interactions.G W Sawyer et al.The Journal of pharmacology and experimental therapeutics, 289(1), 464-476 (1999-03-23) Muscarine activates the sodium-calcium exchanger via M receptors in basal forebrain neurons.Changqing Xu et al.The European journal of neuroscience, 24(8), 2309-2313 (2006-11-01) Selective alkylation of rat urinary bladder muscarinic receptors with 4-DAMP mustard reveals a contractile function for the M2 muscarinic receptor.A S Braverman et al.Journal of receptor and signal transduction research, 19(5), 819-833 (1999-06-01) The use of irreversible ligands to inactivate receptor subtypes: 4-DAMP mustard and muscarinic receptors in smooth muscle.F J Ehlert et al.Life sciences, 62(17-18), 1659-1664 (1998-05-19) The use of 4-diphenylacetoxy-N-(2-chloroethyl)-piperidine (4-DAMP mustard) for estimating the apparent affinities of some agonists acting at muscarinic receptors in guinea-pig ileum.R B Barlow et al.British journal of pharmacology, 102(3), 657-662 (1991-03-01) Phenoxybenzamine and benextramine, but not 4-diphenylacetoxy-N-[2-chloroethyl]piperidine hydrochloride, display irreversible noncompetitive antagonism at G protein-coupled receptors.Johannes Bodenstein et al.The Journal of pharmacology and experimental therapeutics, 314(2), 891-905 (2005-04-29) The interaction of 4-DAMP mustard with subtypes of the muscarinic receptor.F J Ehlert Life sciences, 58(22), 1971-1978 (1996-01-01) Irreversible effects of 4-DAMP mustard on muscarinic receptors in vivo.E A Thomas et al.Proceedings of the Western Pharmacology Society, 35, 233-237 (1992-01-01) Role of curcumin in the prevention of cholinergic mediated cortical dysfunctions in streptozotocin-induced diabetic rats.T Peeyush Kumar et al.Molecular and cellular endocrinology, 331(1), 1-10 (2010-07-20) Inactivation of brain cortex muscarinic receptors by 4-diphenylacetoxy-1-(2-chloroethyl) piperidine mustard.M Waelbroeck et al.Biochemical pharmacology, 44(2), 285-290 (1992-07-22) Characterization of muscarinic receptors in the human bladder mucosa: direct quantification of subtypes using 4-DAMP mustard.Akira Yoshida et al.Urology, 78(3), 721-721 (2011-07-23)

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