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Peer-Reviewed Papers

Protective effect of minocycline on LPS-induced mitochondrial dysfunction and decreased seizure threshold through nitric oxide pathway.Arvin Haj-Mirzaian et al.European journal of pharmacology, 858, 172446-172446 (2019-06-17) Nitric oxide signalling augments neuronal voltage-gated L-type (Ca(v)1) and P/q-type (Ca(v)2.1) channels in the mouse medial nucleus of the trapezoid body.Adam J B Tozer et al.PloS one, 7(2), e32256-e32256 (2012-03-06) Nitric oxide as intracellular modulator: internal production of NO increases neuronal excitability via modulation of several ionic conductances.Liana Artinian et al.The European journal of neuroscience, 36(10), 3333-3343 (2012-08-24) Nitrergic, glutamatergic and gabaergic systems in lithium toxicity.Pınar Yamantürk-Çelik et al.The Journal of toxicological sciences, 37(5), 1017-1023 (2012-10-06) Detection of nitric oxide production in cell cultures by luciferin-luciferase chemiluminescence.Yakov Y Woldman et al.Biochemical and biophysical research communications, 465(2), 232-238 (2015-08-09) Early Recruitment of Cerebral Microcirculation by Neuronal Nitric Oxide Synthase Inhibition in a Juvenile Ischemic Rat Model.P L Leger et al.Cerebrovascular diseases (Basel, Switzerland), 41(1-2), 40-49 (2015-11-26) The selective Rho-kinase inhibitor azaindole-1 has long-lasting erectile activity in the rat.George F Lasker et al.Urology, 81(2), 465-465 (2013-02-05) Effect of 7-nitroindazole, a neuronal nitric oxide synthase inhibitor, on behavioral and physiological parameters.C Brožíčková et al.Physiological research, 63(5), 637-648 (2014-06-09) MALAT1 and HOTAIR Long Non-Coding RNAs Play Opposite Role in Estrogen-Mediated Transcriptional Regulation in Prostate Cancer Cells.Aurora Aiello et al.Scientific reports, 6, 38414-38414 (2016-12-07) Repeated treatment with nitric oxide synthase inhibitor attenuates learned helplessness development in rats and increases hippocampal BDNF expression.Laura Alves Stanquini et al.Acta neuropsychiatrica, 30(3), 127-136 (2017-11-21) Spontaneously hypertensive rats have more orexin neurons in the hypothalamus and enhanced orexinergic input and orexin 2 receptor-associated nitric oxide signalling in the rostral ventrolateral medulla.Yen-Hsien Lee et al.Experimental physiology, 100(9), 993-1007 (2015-06-23) The differential role of NOS inhibitors on stress-induced anxiety and neuroendocrine alterations in the rat.Hye-Young Joung et al.Behavioural brain research, 235(2), 176-181 (2012-08-14) Activation of NOD2/RIPK2 pathway induces mitochondrial injury to oligodendrocyte precursor cells in vitro and CNS demyelination in vivo.Chandramohan Natarajan et al.Journal of neuroimmunology, 265(1-2), 51-60 (2013-10-31) [Influence of D2-receptor blockade on the nitrergic system activity of the nucleus accumbens].N B Saul'skaia et al.Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 98(3), 318-324 (2012-06-01) 3,4-dihydroxybenzalacetone and caffeic acid phenethyl ester induce preconditioning ER stress and autophagy in SH-SY5Y cells.Ryoichi Tomiyama et al.Journal of cellular physiology, 233(2), 1671-1684 (2017-07-07) S-nitrosylation of c-Src via NMDAR-nNOS module promotes c-Src activation and NR2A phosphorylation in cerebral ischemia/reperfusion.Li-Juan Tang et al.Molecular and cellular biochemistry, 365(1-2), 363-377 (2012-03-17) Influence of nitric oxide synthase or cyclooxygenase inhibitors on cannabinoids activity in streptozotocin-induced neuropathy.Magdalena Bujalska-Zadrożny et al.Pharmacological reports : PR, 67(2), 209-216 (2015-02-26) Involvement of neuronal nitric oxide synthase in cross-sensitization between chronic unpredictable stress and ethanol in adolescent and adult mice.Jaqueline Borges Santos-Rocha et al.Alcohol (Fayetteville, N.Y.), 68, 71-79 (2018-03-12) Effects of selective inhibition of nNOS and iNOS on neuropathic pain in rats.P A Rocha et al.Molecular and cellular neurosciences, 105, 103497-103497 (2020-05-01) Antidepressant-like activity of ellagic acid in unstressed and acute immobilization-induced stressed mice.Dinesh Dhingra et al.Pharmacological reports : PR, 64(4), 796-807 (2012-10-23) Why Small Differences Matter: Elucidation of the Mechanisms Underlying the Transformation of 2OH- and 3OH-Carbamazepine in Contact with Sand Filter Material.Elena Brezina et al.Environmental science & technology, 49(17), 10449-10456 (2015-08-25) Anti-dyskinetic effect of the neuronal nitric oxide synthase inhibitor is linked to decrease of FosB/deltaFosB expression.Fernando Eduardo Padovan-Neto et al.Neuroscience letters, 541, 126-131 (2013-02-23) Nitric oxide signaling contributes to ectopic orofacial neuropathic pain.T Sugiyama et al.Journal of dental research, 92(12), 1113-1117 (2013-10-17) 7-Nitroindazole potentiates c-fos expression induced by muscle tendon vibration in the spinal cord.Alexander I Pilyavskii et al.Muscle & nerve, 45(4), 597-602 (2012-03-21) Gardenamide A Protects RGC-5 Cells from H₂O₂-Induced Oxidative Stress Insults by Activating PI3K/Akt/eNOS Signaling Pathway.Rikang Wang et al.International journal of molecular sciences, 16(9), 22350-22367 (2015-09-22) 7-Nitroindazole down-regulates dopamine/DARPP-32 signaling in neostriatal neurons in a rat model of Parkinson's disease.J E Yuste et al.Neuropharmacology, 63(7), 1258-1267 (2012-08-11) [The different roles of the spinal protein nNOS and iNOS in morphine naloxone-precipitated withdrawal response].Hai-lin Liu et al.Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 28(3), 249-253 (2012-08-07) Nitric oxide prevents phosphorylation of neuronal nitric oxide synthase at serine1412 by inhibiting the Akt/PKB and CaM-K II signaling pathways.Tao Song et al.International journal of molecular medicine, 30(1), 15-20 (2012-05-12) Tapentadol and nitric oxide synthase systems.Magdalena Bujalska-Zadrożny et al.Behavioural pharmacology, 26(3), 282-288 (2014-12-09) Cognitive interference as a possible therapeutic strategy to prevent expression of benzodiazepine withdrawal.Emilce Artur de la Villarmois et al.The European journal of neuroscience, 50(11), 3843-3854 (2019-07-13) Possible involvement of GABAergic and nitriergic systems for antianxiety-like activity of piperine in unstressed and stressed mice.Neeraj Gilhotra et al.Pharmacological reports : PR, 66(5), 885-891 (2014-08-26) Pharmacological evidence for the relationship between the NMDA receptor and nitric oxide pathway and the antidepressant-like effects of glucagon-like peptide-2 in the mouse forced-swim test.Sachie Sasaki-Hamada et al.Behavioural brain research, 364, 162-166 (2019-02-20) Inhibition of phosphodiesterase 2 reverses impaired cognition and neuronal remodeling caused by chronic stress.Ying Xu et al.Neurobiology of aging, 36(2), 955-970 (2014-12-03) Essential role for neuronal nitric oxide synthase in acute ethanol-induced motor impairment.James Auta et al.Nitric oxide : biology and chemistry, 100-101, 50-56 (2020-04-13) Rapid membrane effect of estrogens on stimulation of corticotropin-releasing hormone.Yang-Jian Qi et al.Psychoneuroendocrinology, 117, 104680-104680 (2020-05-11) Nitric oxide synthase inhibition decreases l-DOPA-induced dyskinesia and the expression of striatal molecular markers in Pitx3(-/-) aphakia mice.Oscar Solís et al.Neurobiology of disease, 73, 49-59 (2014-10-05) [Synergetic activation of the nucleus accumbens nirtergic system by dopamine D1 and D2 receptor agonists].N B Saul'skaia et al.Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 98(7), 819-826 (2012-10-19) Effects of prolonged neuronal nitric oxide synthase inhibition on the development and expression of L-DOPA-induced dyskinesia in 6-OHDA-lesioned rats.Fernando Eduardo Padovan-Neto et al.Neuropharmacology, 89, 87-99 (2014-09-10) A COX/5-LOX Inhibitor Licofelone Revealed Anticonvulsant Properties Through iNOS Diminution in Mice.Borna Payandemehr et al.Neurochemical research, 40(9), 1819-1828 (2015-07-29) Neuronal nitric oxide synthase inhibition reduces brain damage by promoting collateral recruitment in a cerebral hypoxia-ischemia mice model.J Zhang et al.European review for medical and pharmacological sciences, 22(10), 3166-3172 (2018-06-05) Analysis of the mechanisms underlying the antinociceptive effect of epicatechin in diabetic rats.Geovanna Nallely Quiñonez-Bastidas et al.Life sciences, 93(17), 637-645 (2013-09-10) Age-dependent redox status in the brain stem of NO-deficient hypertensive rats.Miroslava Majzúnová et al.Journal of biomedical science, 24(1), 72-72 (2017-09-13) Glutamate, nitric oxide and cell-cell signalling in the nervous system.J Garthwaite Trends in neurosciences, 14(2), 60-67 (1991-02-01) The Importance of L-Arginine:NO:cGMP Pathway in Tolerance to Flunitrazepam in Mice.Sylwia Talarek et al.Neurotoxicity research, 31(2), 309-316 (2016-12-14) Hypoxia-induced relaxation of porcine retinal arterioles in vitro depends on inducible NO synthase and EP4 receptor stimulation in the perivascular retina.Pernille Oversø Hansen et al.Acta ophthalmologica, 93(5), 457-463 (2015-01-27) Biphasic effect of sumatriptan on PTZ-induced seizures in mice: Modulation by 5-HT1B/D receptors and NOS/NO pathway.Maziar Gooshe et al.European journal of pharmacology, 824, 140-147 (2018-02-08) Biochemical and histopathological evidence for the beneficial effects of modafinil on the rat model of inflammatory bowel disease: involvement of nitric oxide pathway.Pegah Dejban et al.Pharmacological reports : PR, 72(1), 135-146 (2020-02-06) Genotoxicity of microcystin-LR in mammalian cells: Implication from peroxynitrite produced by mitochondria.Xiaofei Wang et al.Ecotoxicology and environmental safety, 195, 110408-110408 (2020-03-18) S-Nitrosylation of proline-rich tyrosine kinase 2 involves its activation induced by oxygen-glucose deprivation.Xian-Liang Yan et al.Neuroscience letters, 597, 90-96 (2015-05-02) The effect of a selective neuronal nitric oxide synthase inhibitor 3-bromo 7-nitroindazole on spatial learning and memory in rats.Semil Selcen Gocmez et al.Pharmacology, biochemistry, and behavior, 131, 19-25 (2015-02-01) Involvement of neuronal nitric oxide synthase in desensitisation of µ-opioid receptors in the rat locus coeruleus.María T Santamarta et al.Journal of psychopharmacology (Oxford, England), 28(10), 903-914 (2014-06-26) Role of glutamate receptors and nitric oxide on the effects of glufosinate ammonium, an organophosphate pesticide, on in vivo dopamine release in rat striatum.Lilian R F Faro et al.Toxicology, 311(3), 154-161 (2013-07-03) Neuroprotective effect of chlorogenic acid in global cerebral ischemia-reperfusion rat model.Gaurav Kumar et al.Naunyn-Schmiedeberg's archives of pharmacology, 392(10), 1293-1309 (2019-06-14) Fear renewal requires nitric oxide signaling in the lateral amygdala.Sukwoon Song et al.Biochemical and biophysical research communications, 523(1), 86-90 (2019-12-14) Neuronal Nitric Oxide Synthase Contributes to PTZ Kindling Epilepsy-Induced Hippocampal Endoplasmic Reticulum Stress and Oxidative Damage.Xinjian Zhu et al.Frontiers in cellular neuroscience, 11, 377-377 (2017-12-14) Cerebral ischemia-reperfusion induces GAPDH S-nitrosylation and nuclear translocation.Chong Li et al.Biochemistry. Biokhimiia, 77(6), 671-678 (2012-07-24) Effects of chronic neuronal nitric oxide-synthase inhibition on arterial function and structure in spontaneously hypertensive rats.S Cacanyiova et al.Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 63(1), 23-28 (2012-03-31) [Mediolateral gradient of the nucleus accumbens nitrergic activation during exploratory behavior].N B Saul'skaia et al.Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 98(4), 461-468 (2012-07-28) Chemically Bonding of Amantadine with Gardenamide A Enhances the Neuroprotective Effects against Corticosterone-Induced Insults in PC12 Cells.Jiaqiang Zhao et al.International journal of molecular sciences, 16(9), 22795-22810 (2015-09-25) Antidepressant-like effect of quercetin in bulbectomized mice and involvement of the antioxidant defenses, and the glutamatergic and oxidonitrergic pathways.Iandra Holzmann et al.Pharmacology, biochemistry, and behavior, 136, 55-63 (2015-07-22) Cell-specific regulation of neuronal activity by endogenous production of nitric oxide.Lei Ray Zhong et al.The European journal of neuroscience, 41(8), 1013-1024 (2015-03-27) Inhibition of the neuronal nitric oxide synthase potentiates homocysteine thiolactone-induced seizures in adult rats.Dragan Hrncić et al.Medicinal chemistry (Shariqah (United Arab Emirates)), 8(1), 59-64 (2012-03-17) The Effects of Sub-Chronic Treatment with Aripiprazole on Pentylenetetrazole- and Electroshock-Induced Seizures in Mice: The Role of Nitric Oxide.Leila Moezi et al.Pharmacology, 95(5-6), 264-270 (2015-05-30) Anticonvulsant effect of minocycline on pentylenetetrazole-induced seizure in mice: involvement of nitric oxide and N-methyl-d-aspartate receptor.Hossein Amini-Khoei et al.Canadian journal of physiology and pharmacology, 96(8), 742-750 (2018-03-21) Serum IgG-induced microglial activation enhances neuronal cytolysis via the NO/sGC/PKG pathway in children with opsoclonus-myoclonus syndrome and neuroblastoma.Xu Ding et al.Journal of neuroinflammation, 17(1), 190-190 (2020-06-18) Licofelone Attenuates LPS-induced Depressive-like Behavior in Mice: A Possible Role for Nitric Oxide.Seyyedeh Elaheh Mousavi et al.Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 21(1), 184-194 (2018-05-24) Involvement of NO/cGMP pathway in the antidepressant-like effect of gabapentin in mouse forced swimming test.Sattar Ostadhadi et al.Naunyn-Schmiedeberg's archives of pharmacology, 389(4), 393-402 (2016-01-13) [Signals of danger inhibit exploration-induced activation of the nitrergic system of the nucleus accumbens].N B Saul'skaia et al.Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova, 62(4), 475-484 (2012-10-06) Interaction of Constitutive Nitric Oxide Synthases with Cyclooxygenases in Regulation of Bicarbonate Secretion in the Gastric Mucosa.V A Zolotarev et al.Bulletin of experimental biology and medicine, 163(1), 6-9 (2017-06-04) Effect of Interaction between Adenosine and Nitric Oxide on Central Nervous System Oxygen Toxicity.Cheng-Wei Xie et al.Neurotoxicity research, 36(1), 193-203 (2019-03-31) Selective Nitric Oxide Synthase Inhibitor 7-Nitroindazole Protects against Cocaine-Induced Oxidative Stress in Rat Brain.Vessela Vitcheva et al.Oxidative medicine and cellular longevity, 2015, 157876-157876 (2015-11-18) Contribution of nitric oxide-dependent guanylate cyclase and reactive oxygen species signaling pathways to desensitization of μ-opioid receptors in the rat locus coeruleus.Patricia Pablos et al.Neuropharmacology, 99, 422-431 (2015-08-10) Nitrite Protects Neurons Against Hypoxic Damage Through S-nitrosylation of Caspase-6.Yen-Jung Chen et al.Antioxidants & redox signaling, 31(2), 109-126 (2018-11-13) MicroRNA-126 protects against vascular injury by promoting homing and maintaining stemness of late outgrowth endothelial progenitor cells.Chong Zhe Pei et al.Stem cell research & therapy, 11(1), 28-28 (2020-01-23) Evaluation of Glomerular Hemodynamic Function by Empagliflozin in Diabetic Mice Using In Vivo Imaging.Kengo Kidokoro et al.Circulation, 140(4), 303-315 (2019-02-19) Involvement of PKA-dependent upregulation of nNOS-CGRP in adrenomedullin-initiated mechanistic pathway underlying CFA-induced response in rats.Dongmei Wang et al.Experimental neurology, 239, 111-119 (2012-10-16) Inflammatory stimuli induce inhibitory S-nitrosylation of the deacetylase SIRT1 to increase acetylation and activation of p53 and p65.Shohei Shinozaki et al.Science signaling, 7(351), ra106-ra106 (2014-11-13) The involvement of NMDA receptor/NO/cGMP pathway in the antidepressant like effects of baclofen in mouse force swimming test.Muhammad Imran Khan et al.Neuroscience letters, 612, 52-61 (2015-12-19) The role of striatum and prefrontal cortex in the prevention of amphetamine-induced schizophrenia-like effects mediated by nitric oxide compounds.Ana Carolina Issy et al.Progress in neuro-psychopharmacology & biological psychiatry, 86, 353-362 (2018-03-21) HSP70 protects rats and hippocampal neurons from central nervous system oxygen toxicity by suppression of NO production and NF-κB activation.Hongjie Yi et al.Experimental biology and medicine (Maywood, N.J.), 243(9), 770-779 (2018-05-16) Function of neuronal nitric oxide synthase enzyme in temozolomide-induced damage of astrocytic tumor cells.Fernando Francisco Borges Resende et al.Oncology letters, 15(4), 4891-4899 (2018-03-20) NMDA-induced nitric oxide generation and CREB activation in central nervous system is dependent on eukaryotic elongation factor 2 kinase.Luis Felipe Homem Gladulich et al.Biochimica et biophysica acta. Molecular cell research, 1867(10), 118783-118783 (2020-06-23) Neuronal nitric oxide synthase inhibition attenuates the development of L-DOPA-induced dyskinesia in hemi-Parkinsonian rats.Kazuhiro Takuma et al.European journal of pharmacology, 683(1-3), 166-173 (2012-03-28) Neuronal nitric oxide inhibits intestinal smooth muscle growth.Anne-Marie Pelletier et al.American journal of physiology. Gastrointestinal and liver physiology, 298(6), G896-G907 (2010-03-27) Site-specific Effects of DUOX1-Related Peroxidase on Intercellular Apoptosis Signaling.Sonja Heinzelmann et al.Anticancer research, 35(11), 5955-5971 (2015-10-28) Hydrogen peroxide and nitric oxide induce anticontractile effect of perivascular adipose tissue via renin angiotensin system activation.Natália Nóbrega et al.Nitric oxide : biology and chemistry, 84, 50-59 (2019-01-07) Chloroquine-induced scratching is mediated by NO/cGMP pathway in mice.Arash Foroutan et al.Pharmacology, biochemistry, and behavior, 134, 79-84 (2015-05-11) Coupling of ascorbate and nitric oxide dynamics in vivo in the rat hippocampus upon glutamatergic neuronal stimulation: a novel functional interplay.Nuno R Ferreira et al.Brain research bulletin, 114, 13-19 (2015-03-19) Possible involvement of L-arginine-nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) signaling pathway in the antidepressant-like effect of Wuling mycelia powder in rat.Yun-Fei Tan et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 78, 60-65 (2016-02-24) Antidepressant-like effect of quercetin in bulbectomized mice and involvement of the antioxidant defenses, and the glutamatergic and oxidonitrergic pathways.Iandra Holzmann et al.Pharmacology, biochemistry, and behavior, 136, 55-63 (2015-07-22) Involvement of the insular nitric oxide signaling pathway in the expression of morphine-induced conditioned place preference in rats.Peng Ma et al.Neuroreport, 25(9), 641-646 (2014-05-08) Retinal arteriole reactivity in mice lacking the endothelial nitric oxide synthase (eNOS) gene.Adrian Gericke et al.Experimental eye research, 181, 150-156 (2019-02-05) Imidazole-induced contractility of vascular smooth muscle cells in the presence of U-73122, ODQ, indomethacin and 7-nitroindazole.M Wiciński et al.Polish journal of veterinary sciences, 16(2), 293-297 (2013-08-27) Cerebral blood flow increase during prolonged hyperbaric oxygen exposure may not be necessary for subsequent convulsion.Xiang Xiao et al.CNS neuroscience & therapeutics, 18(11), 947-949 (2012-10-31) Chemically Bonding of Amantadine with Gardenamide A Enhances the Neuroprotective Effects against Corticosterone-Induced Insults in PC12 Cells.Jiaqiang Zhao et al.International journal of molecular sciences, 16(9), 22795-22810 (2015-09-25) Prevention of the degeneration of human dopaminergic neurons in an astrocyte co-culture system allowing endogenous drug metabolism.Liudmila Efremova et al.British journal of pharmacology, 172(16), 4119-4132 (2015-05-20) Tubuloglomerular feedback responses in offspring of dexamethasone-treated ewes.Anita J Turner et al.American journal of physiology. Renal physiology, 313(4), F864-F873 (2017-07-07) Normobaric hyperoxia stimulates superoxide and nitric oxide production in the caudal solitary complex of rat brain slices.Geoffrey E Ciarlone et al.American journal of physiology. Cell physiology, 311(6), C1014-C1026 (2016-10-14) Neuronal nitric oxide inhibition attenuates the protective effect of HBO2 during cyanide poisoning.Morten Hedetoft et al.Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 45(3), 335-350 (2018-07-22)

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