Melting point	102-106 ºC

Symbol(GHS)	Xi
Hazard Codes	R36/37/38
SDS/MSDS	S26;S36

Source	SDS/MSDS Samples
Alfa-Aesar	View & Download
Sigma-Aldrich	View & Download
TCI	View & Download

Synthetic Route

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Articles

Peer-Reviewed Papers

Induction of EROD activity by 1-phenylimidazole and beta-naphthoflavone in rainbow trout cultured hepatocytes: a comparative study.A Jos et al.Toxicology in vitro : an international journal published in association with BIBRA, 21(7), 1307-1310 (2007-05-25) Acrolein genotoxicity in Drosophila melanogaster. III. Effects of metabolism modification.A R Barros et al.Mutation research, 321(3), 119-126 (1994-05-01) Interplanar torsion in the S1<--S0 electronic spectrum of jet cooled 1-phenylimidazole.Evan G Robertson et al.The Journal of chemical physics, 121(24), 12421-12427 (2004-12-21) Effects of Asp-369 and Arg-372 mutations on heme environment and function in human endothelial nitric-oxide synthase.P F Chen et al.The Journal of biological chemistry, 273(51), 34164-34170 (1998-12-16) Interferon-gamma-inducible murine macrophage nitric oxide synthase: studies on the mechanism of inhibition by imidazole agents.D J Wolff et al.Archives of biochemistry and biophysics, 311(2), 293-299 (1994-06-01) The inhibition of the constitutive bovine endothelial nitric oxide synthase by imidazole and indazole agents.D J Wolff et al.Archives of biochemistry and biophysics, 314(2), 360-366 (1994-11-01) Three-dimensional pharmacophore hypotheses for the locust neuronal octopamine receptor (OAR3). Part 2: agonists.A Hirashima et al.Bioorganic & medicinal chemistry, 7(7), 1437-1443 (1999-08-28) Selectivity of 1-phenylimidazole as a ligand for cytochrome P-450 and as an inhibitor of microsomal oxidation.C F Wilkinson et al.Biochemical pharmacology, 32(6), 997-1003 (1983-03-15) Cationic iridium(III) complexes with two carbene-based cyclometalating ligands: cis versus trans isomers.Filippo Monti et al.Inorganic chemistry, 54(6), 3031-3042 (2015-03-06) In vitro toxicity of perfluorooctane sulfonate on rat liver hepatocytes: probability of distructive binding to CYP 2E1 and involvement of cellular proteolysis.Mehdi Rajabnia Khansari et al.Environmental science and pollution research international, 24(29), 23382-23388 (2017-08-27) The involvement of cytochrome P450 peroxidase in the metabolic bioactivation of cumene hydroperoxide by isolated rat hepatocytes.M R Anari et al.Chemical research in toxicology, 9(6), 924-931 (1996-09-01) Cytochrome P-450 and monooxygenase activity in hepatic microsomes from N-phenylimidazole-treated rats.M Murray et al.Toxicology letters, 25(2), 191-198 (1985-05-01) Influence of inhibition of the metabolic activation on the mutagenicity of some nitrosamines, triazenes, hydrazines and seniciphylline in Drosophila melanogaster.J A Zijlstra et al.Mutation research, 202(1), 251-267 (1988-11-01) Expression, purification and characterization of cytochrome P450 Biol: a novel P450 involved in biotin synthesis in Bacillus subtilis.A J Green et al.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 6(5-6), 523-533 (2001-07-27) Calmodulin-dependent nitric-oxide synthase. Mechanism of inhibition by imidazole and phenylimidazoles.D J Wolff et al.The Journal of biological chemistry, 268(13), 9425-9429 (1993-05-05) Biotransformation of caffeine by microsomes from human liver. Kinetics and inhibition studies.D M Grant et al.Biochemical pharmacology, 36(8), 1251-1260 (1987-04-15) The effect of mixed-function oxidase and amine oxidase inhibitors on the activation of dialkylnitrosamines and 1,2-dimethylhydrazine to bacterial mutagens in mice.P R Kerklaan et al.Journal of cancer research and clinical oncology, 111(3), 196-202 (1986-01-01) Chloroform-induced cytolethality in freshly isolated male B6C3F1 mouse and F-344 rat hepatocytes.P Ammann et al.Toxicology and applied pharmacology, 149(2), 217-225 (1998-05-08) Synthesis and identification of the quaternary ammonium-linked glucuronide of 1-phenylimidazole in human liver microsomes and investigation of the human UDP-glucuronosyltransferases involved.S C Vashishtha et al.Drug metabolism and disposition: the biological fate of chemicals, 28(9), 1009-1013 (2000-08-19) Active-site structure analysis of recombinant human inducible nitric oxide synthase using imidazole.R M Chabin et al.Biochemistry, 35(29), 9567-9575 (1996-07-23) Chemotaxis by Pseudomonas putida (ATCC 17453) towards camphor involves cytochrome P450cam (CYP101A1).Priyadarshini Balaraman et al.Biochimica et biophysica acta. General subjects, 1863(2), 304-312 (2018-11-06) Inhibition of cytochrome P-450c-mediated benzo[a]pyrene hydroxylase and ethoxyresorufin O-deethylase by dihydrosafrole.L R Kao et al.Xenobiotica; the fate of foreign compounds in biological systems, 17(7), 793-805 (1987-07-01) Metabolic inactivation of mutagens in Drosophila melanogaster.J A Zijlstra et al.Mutation research, 198(1), 73-83 (1988-03-01) The inhibition of the constitutive and inducible nitric oxide synthase isoforms by indazole agents.D J Wolff et al.Archives of biochemistry and biophysics, 311(2), 300-306 (1994-06-01)

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