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7-Aminocephalosporanic acid | CAS:957-68-6
7-Aminocephalosporanic acid
  • Name:7-Aminocephalosporanic acid
  • CAS:957-68-6
  • Synonyms:7-ACA; (6R,7S)-3-(Acetyloxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • Molecular Formula:C10H12N2O5S
  • Molecular Weight:272.27
  • EINESC:213-485-0

Description

Properties

Melting point 300 ºC
Specific optical rotation 94 º (c=0.5, KH2PO4, PH 7)

Safety

Symbol(GHS) Xi
Hazard Codes R42/43
SDS/MSDS S24/25

SDS

Source SDS/MSDS Samples
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Synthetic Route
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Articles
Peer-Reviewed Papers
DNA binding, antioxidant activity, and DNA damage protection of chiral macrocyclic Mn(III) salen complexes.Nirali Pandya et al.Chirality, 24(12), 1063-1073 (2012-09-13) Fluorimetric study of the pro-oxidant activity of EUK8 in the presence of hydrogen peroxide.Samanta Do Amaral et al.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 21(4), 425-432 (2007-12-29) Apoptosis-inducing factor regulates skeletal muscle progenitor cell number and muscle phenotype.Anne-Sophie Armand et al.PloS one, 6(11), e27283-e27283 (2011-11-15) Role of superoxide dismutase enzymes and ascorbate in protection of nitrergic relaxation against superoxide anions in mouse duodenum.M Ata Secilmis et al.Acta pharmacologica Sinica, 29(6), 687-697 (2008-05-27) Amelioration of diet-induced nonalcoholic steatohepatitis in rats by Mn-salen complexes via reduction of oxidative stress.Alireza Rezazadeh et al.Journal of biomedical science, 19, 26-26 (2012-03-02) Chiral catalysis in nanopores of mesoporous materials.Can Li et al.Chemical communications (Cambridge, England), (6)(6), 547-558 (2007-02-01) Antioxidant, EUK-8, prevents murine dilated cardiomyopathy.Satoru Kawakami et al.Circulation journal : official journal of the Japanese Circulation Society, 73(11), 2125-2134 (2009-09-15) Age-related increase of superoxide generation in the brains of mammals and birds.Toru Sasaki et al.Aging cell, 7(4), 459-469 (2008-04-19) Biomimetic in vitro oxidation of lapachol: a model to predict and analyse the in vivo phase I metabolism of bioactive compounds.Michael Niehues et al.European journal of medicinal chemistry, 54, 804-812 (2012-07-17) Salen-manganese complexes: sophisticated tools for the analysis of intercellular ROS signaling pathways.Stefanie J Ophoven et al.Anticancer research, 30(10), 3967-3979 (2010-11-03) Manganese salen complexes with acid-base catalytic auxiliary: functional mimetics of catalase.Yukinobu Noritake et al.Inorganic chemistry, 52(7), 3653-3662 (2013-03-14) Enhanced catalase-like activity of manganese salen complexes in water: effect of a three-dimensionally fixed auxiliary.Yoritada Watanabe et al.Chemical communications (Cambridge, England), (47)(47), 4958-4960 (2006-12-01) Structure-activity relationship of 15 different Mn-salen derivatives against free radicals.Sakineh Meftah et al.Drug and chemical toxicology, 36(1), 9-18 (2012-01-24) Restraint stress up-regulates lectin-like oxidized low-density lipoprotein receptor-1 in aorta of apolipoprotein E-deficient mice.Irene J Andersson et al.Stress (Amsterdam, Netherlands), 13(5), 454-460 (2010-07-30) Superexpanded Prussian-blue analogue with [Fe(CN)6]4-, [Nb6Cl12(CN)6]4-, and [Mn(salen)]+ as building units.Jianjun Zhang et al.Journal of the American Chemical Society, 129(2), 250-251 (2007-01-11) The protein environment drives selectivity for sulfide oxidation by an artificial metalloenzyme.Pierre Rousselot-Pailley et al.Chembiochem : a European journal of chemical biology, 10(3), 545-552 (2009-01-13) Mitochondrial protection and the reversal of left ventricular remodeling.Motoaki Sano Circulation journal : official journal of the Japanese Circulation Society, 73(11), 2017-2018 (2009-10-24) Catalase and epoxidation activity of manganese salen complexes bearing two xanthene scaffolds.Jenny Y Yang et al.Journal of the American Chemical Society, 129(26), 8192-8198 (2007-06-08) Prooxidant activity of the superoxide dismutase (SOD)-mimetic EUK-8 in proliferating and growth-arrested Escherichia coli cells.Filip Matthijssens et al.Free radical biology & medicine, 45(5), 708-715 (2008-06-25) Salen Mn complexes mitigate radiation injury in normal tissues.Rosalind A Rosenthal et al.Anti-cancer agents in medicinal chemistry, 11(4), 359-372 (2011-04-02) Asymmetric epoxidation of unfunctionalized alkenes catalyzed by sugar moiety-modified chiral salen-Mn(III) complexes.Jiquan Zhao et al.Carbohydrate research, 344(1), 61-66 (2008-11-11) Antioxidant therapy attenuates myocardial telomerase activity reduction in superoxide dismutase-deficient mice.Naoki Makino et al.Journal of molecular and cellular cardiology, 50(4), 670-677 (2011-01-05)
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