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ATM regulates 3-methylpurine-DNA glycosylase and promotes therapeutic resistance to alkylating agents.Sameer Agnihotri et al.Cancer discovery, 4(10), 1198-1213 (2014-08-08) Downregulation of BRCA1-BRCA2-containing complex subunit 3 sensitizes glioma cells to temozolomide.Kit Man Chai et al.Oncotarget, 5(21), 10901-10915 (2014-10-23) Expression of eukaryotic initiation factor 5A and hypusine forming enzymes in glioblastoma patient samples: implications for new targeted therapies.Michael Preukschas et al.PloS one, 7(8), e43468-e43468 (2012-08-29) Primary central nervous system diffuse large B cell lymphoma transformed from orbital mucosa-associated lymphoid tissue lymphoma: complete response to combined intrathecal and systemic rituximab.Huai-Cheng Huang et al.Annals of hematology, 92(7), 989-992 (2012-12-18) Loss of O⁶-methylguanine-DNA methyltransferase confers collateral sensitivity to carmustine in topoisomerase II-mediated doxorubicin resistant triple negative breast cancer cells.Selina Raguz et al.Biochemical pharmacology, 85(2), 186-196 (2012-11-06) Uveal Melanoma Metastatic to the Liver: Chemoembolization With 1,3-Bis-(2-Chloroethyl)-1-Nitrosourea.Carin F Gonsalves et al.AJR. American journal of roentgenology, 205(2), 429-433 (2015-04-24) Carbamoylating activity associated with the activation of the antitumor agent laromustine inhibits angiogenesis by inducing ASK1-dependent endothelial cell death.Weidong Ji et al.PloS one, 9(7), e103224-e103224 (2014-07-30) Chemoselection of allogeneic HSC after murine neonatal transplantation without myeloablation or post-transplant immunosuppression.Rustom Falahati et al.Molecular therapy : the journal of the American Society of Gene Therapy, 20(11), 2180-2189 (2012-08-09) Allogeneic stem cell transplantation for relapsed or refractory lymphoma after conditioning with BEAM/fludarabine/TBI.Alix O'Meara et al.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 19(1), 82-86 (2012-08-18) Acute kidney injury requiring dialysis following carmustine and etoposide during autologous stem cell transplantation.Jane Li et al.Chemotherapy, 58(5), 349-351 (2012-11-23) Mechanism of glutathione-mediated DNA damage by the antineoplastic agent 1,3-bis(2-chloroethyl)-N-nitrosourea.W Stahl et al.Chemical research in toxicology, 5(1), 106-109 (1992-01-01) Topical carmustine (BCNU) in the treatment of mycosis fungoides.Herschel S Zackheim Dermatologic therapy, 16(4), 299-302 (2003-12-23) [II. Current status of BCNU stent in the brain for treatment of glioma].Tomokazu Aoki et al.Gan to kagaku ryoho. Cancer & chemotherapy, 40(6), 708-717 (2013-08-21) Pharmacokinetics of the carmustine implant.Alison B Fleming et al.Clinical pharmacokinetics, 41(6), 403-419 (2002-06-21) F2A sequence linking MGMT(P140K) and MDR1 in a bicistronic lentiviral vector enables efficient chemoprotection of haematopoietic stem cells.P Maier et al.Cancer gene therapy, 19(11), 802-810 (2012-10-06) DexaBEAM versus ICE salvage regimen prior to autologous transplantation for relapsed or refractory aggressive peripheral T cell lymphoma: a retrospective evaluation of parallel patient cohorts of one center.Jan-Henrik Mikesch et al.Annals of hematology, 92(8), 1041-1048 (2013-03-28) Iodine-131 rituximab radioimmunotherapy with BEAM conditioning and autologous stem cell transplant salvage therapy for relapsed/refractory aggressive non-Hodgkin lymphoma.Paul C Kruger et al.Cancer biotherapy & radiopharmaceuticals, 27(9), 552-560 (2012-10-16) Systems metabolic engineering: genome-scale models and beyond.John Blazeck et al.Biotechnology journal, 5(7), 647-659 (2010-02-13) Antiangiogenic-targeting drug-loaded microbubbles combined with focused ultrasound for glioma treatment.Ching-Hsiang Fan et al.Biomaterials, 34(8), 2142-2155 (2012-12-19) Mismatch repair deficiency endows tumors with a unique mutation signature and sensitivity to DNA double-strand breaks.Zhao H, Thienpont B, Yesilyurt BT, et al. eLife, 3, e02725-e02725 (2014) High-dose etoposide in allogeneic stem cell transplantation.Oystein Bruserud et al.Cancer chemotherapy and pharmacology, 70(6), 765-782 (2012-10-12) Carmustine induces platelet apoptosis.Jie Zhang et al.Platelets, 26(5), 437-442 (2014-06-24) Nordic MCL3 study: 90Y-ibritumomab-tiuxetan added to BEAM/C in non-CR patients before transplant in mantle cell lymphoma.Arne Kolstad et al.Blood, 123(19), 2953-2959 (2014-03-22) Allogeneic stem cell transplantation for relapsed or refractory lymphoma after conditioning with BEAM/fludarabine/TBI.Alix O'Meara et al.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 19(1), 82-86 (2012-08-18) 16th Int?l. Sympos. High Voltage Eng (2016) Prospective study of carmustine wafers in combination with 6-month metronomic temozolomide and radiation therapy in newly diagnosed glioblastoma: preliminary results.Andrea Salmaggi et al.Journal of neurosurgery, 118(4), 821-829 (2013-01-29) The role of cytotoxic chemotherapy in the management of progressive glioblastoma : a systematic review and evidence-based clinical practice guideline.Jeffrey J Olson et al.Journal of neuro-oncology, 118(3), 501-555 (2014-04-18) The effectiveness and cost-effectiveness of carmustine implants and temozolomide for the treatment of newly diagnosed high-grade glioma: a systematic review and economic evaluation.R Garside et al.Health technology assessment (Winchester, England), 11(45), iii-iiv (2007-11-15) Contribution of involved-field radiotherapy to survival in patients with relapsed or refractory Hodgkin lymphoma undergoing autologous stem cell transplantation.Celalettin Eroglu et al.American journal of clinical oncology, 38(1), 68-73 (2013-04-09) Induction of β-glucuronidase release by cytostatic agents in small tumors.Inês F Antunes et al.Molecular pharmaceutics, 9(11), 3277-3285 (2012-09-27) Targeted nitric oxide delivery preferentially induces glioma cell chemosensitivity via altered p53 and O(6) -methylguanine-DNA methyltransferase activity.Shahana Safdar et al.Biotechnology and bioengineering, 110(4), 1211-1220 (2012-11-06) Effective elimination of cancer stem cells by a novel drug combination strategy.Shuqiang Yuan et al.Stem cells (Dayton, Ohio), 31(1), 23-34 (2012-11-08) Cancer chemotherapy and cardiac arrhythmias: a review.Juan Tamargo et al.Drug safety, 38(2), 129-152 (2015-01-13) IRF7 promotes glioma cell invasion by inhibiting AGO2 expression.Jun-Kyum Kim et al.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 36(7), 5561-5569 (2015-02-15) Microcolony Size Distribution Assay Enables High-Throughput Cell Survival Quantitation.Le P Ngo et al.Cell reports, 26(6), 1668-1678 (2019-02-07) Chemoselection of allogeneic HSC after murine neonatal transplantation without myeloablation or post-transplant immunosuppression.Rustom Falahati et al.Molecular therapy : the journal of the American Society of Gene Therapy, 20(11), 2180-2189 (2012-08-09) The combination of carmustine wafers and temozolomide for the treatment of malignant gliomas. A comprehensive review of the rationale and clinical experience.A Gutenberg et al.Journal of neuro-oncology, 113(2), 163-174 (2013-03-29) Lentiviral MGMT(P140K)-mediated in vivo selection employing a ubiquitous chromatin opening element (A2UCOE) linked to a cellular promoter.Ruhi Phaltane et al.Biomaterials, 35(25), 7204-7213 (2014-05-31) Carmustine wafers: localized delivery of chemotherapeutic agents in CNS malignancies.Steven H Lin et al.Expert review of anticancer therapy, 8(3), 343-359 (2008-03-28) Safety profile of carmustine wafers in malignant glioma: a review of controlled trials and a decade of clinical experience.Michael Sabel et al.Current medical research and opinion, 24(11), 3239-3257 (2008-10-23) Activation of the NRF2 pathway and its impact on the prognosis of anaplastic glioma patients.Masayuki Kanamori et al.Neuro-oncology, 17(4), 555-565 (2014-10-12) The nitrosoureas: carmustine (BCNU) and lomustine (CCNU).R B Weiss et al.Cancer treatment reviews, 9(4), 313-330 (1982-12-01) Synaptic NMDA receptor activity is coupled to the transcriptional control of the glutathione system.Paul S Baxter et al.Nature communications, 6, 6761-6761 (2015-04-10) Convection enhanced delivery of carmustine to the murine brainstem: a feasibility study.A Charlotte P Sewing et al.Journal of neuroscience methods, 238, 88-94 (2014-09-30) Safety and activity of a new intensive short-term chemoimmunotherapy in HIV-positive patients with Burkitt lymphoma.Andrés J M Ferreri et al.British journal of haematology, 159(2), 252-255 (2012-08-29) Drug-loaded bubbles with matched focused ultrasound excitation for concurrent blood-brain barrier opening and brain-tumor drug delivery.Ching-Hsiang Fan et al.Acta biomaterialia, 15, 89-101 (2015-01-13) Submicron-bubble-enhanced focused ultrasound for blood-brain barrier disruption and improved CNS drug delivery.Ching-Hsiang Fan et al.PloS one, 9(5), e96327-e96327 (2014-05-03) Foamy viral vector integration sites in SCID-repopulating cells after MGMTP140K-mediated in vivo selectionOlszko ME, et al Gene Therapy, 22(7), 591-591 (2015) Integrated redox sensor and effector functions for tetrahydrobiopterin- and glutathionylation-dependent endothelial nitric-oxide synthase uncoupling.Mark J Crabtree et al.The Journal of biological chemistry, 288(1), 561-569 (2012-11-10) Resveratrol and curcumin synergistically induces apoptosis in cigarette smoke condensate transformed breast epithelial cells through a p21(Waf1/Cip1) mediated inhibition of Hh-Gli signaling.Purusottam Mohapatra et al.The international journal of biochemistry & cell biology, 66, 75-84 (2015-07-28) Overexpression of Nrf2 attenuates Carmustine-induced cytotoxicity in U87MG human glioma cells.Sangeetha Sukumari-Ramesh et al.BMC cancer, 15, 118-118 (2015-04-09) The lymphoma-like polychemotherapy regimen "Dexa-BEAM" in advanced and extramedullary multiple myeloma.Leo Rasche et al.Annals of hematology, 93(7), 1207-1214 (2014-02-15) MicroRNA-221 targeting PI3-K/Akt signaling axis induces cell proliferation and BCNU resistance in human glioblastoma.Qiang Xie et al.Neuropathology : official journal of the Japanese Society of Neuropathology, 34(5), 455-464 (2014-05-02) Epidermal growth factor receptor variant III renders glioma cancer cells less differentiated by JAGGED1.Eun-Jung Kim et al.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 36(4), 2921-2928 (2014-12-18) Current medical treatment of glioblastoma.Vyshak Alva Venur et al.Cancer treatment and research, 163, 103-115 (2014-12-04) Phase II trial of 131-Iodine tositumomab with high-dose chemotherapy and autologous stem cell transplantation for relapsed diffuse large B cell lymphoma.Julie M Vose et al.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 19(1), 123-128 (2012-09-04) Mapping the human kinome in response to DNA damageOwusu M, et al. Testing, 26(3), 555-563 (2019) Downregulation of hPMC2 imparts chemotherapeutic sensitivity to alkylating agents in breast cancer cells.Nirmala Krishnamurthy et al.Cancer biology & therapy, 16(4), 518-527 (2015-04-08) Growth pattern of tumor recurrence following bis-chloroethylnitrosourea (BCNU) wafer implantation in malignant glioma.Lutz Dörner et al.Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 20(3), 429-434 (2013-01-15) Development of multifunctional lipid nanocapsules for the co-delivery of paclitaxel and CpG-ODN in the treatment of glioblastoma.Giovanna Lollo et al.International journal of pharmaceutics, 495(2), 972-980 (2015-10-03) Role for cytotoxic chemotherapy in patients with recurrent glioblastoma progressing on bevacizumab: a retrospective case series.Marc C Chamberlain Expert review of neurotherapeutics, 12(8), 929-936 (2012-09-26) Inhibitors of hydroperoxide metabolism enhance ascorbate-induced cytotoxicity.K E Olney et al.Free radical research, 47(3), 154-163 (2012-12-05) 3-Bromopyruvate regulates the status of glycolysis and BCNU sensitivity in human hepatocellular carcinoma cells.Xiaodong Sun et al.Biochemical pharmacology, 177, 113988-113988 (2020-04-25) Fumarate Upregulates Surface Expression of ULBP2/ULBP5 by Scavenging Glutathione Antioxidant Capacity.Rikke Illum Høgh et al.Journal of immunology (Baltimore, Md. : 1950), 204(7), 1746-1759 (2020-03-08) Sustainable release of carmustine from biodegradable poly[((D,L))-lactide-co-glycolide] nanofibrous membranes in the cerebral cavity: in vitro and in vivo studies.Yuan-Yun Tseng et al.Expert opinion on drug delivery, 10(7), 879-888 (2013-01-08) Role of dimerization in the catalytic properties of the Escherichia coli disulfide isomerase DsbC.Silvia A Arredondo et al.The Journal of biological chemistry, 284(36), 23972-23979 (2009-07-08) Combining CDK4/6 inhibitors ribociclib and palbociclib with cytotoxic agents does not enhance cytotoxicity.Dan Jin et al.PloS one, 14(10), e0223555-e0223555 (2019-10-11) Simple genetic selection protocol for isolation of overexpressed genes that enhance accumulation of membrane-integrated human G protein-coupled receptors in Escherichia coli.Georgios Skretas et al.Applied and environmental microbiology, 76(17), 5852-5859 (2010-07-20) BCNU wafer placement with temozolomide (TMZ) in the immediate postoperative period after tumor resection followed by radiation therapy with TMZ in patients with newly diagnosed high grade glioma: final results of a prospective, multi-institutional, phase II trial.Stuart H Burri et al.Journal of neuro-oncology, 123(2), 259-266 (2015-05-08) Treatment outcome in children and adolescents with relapsed Hodgkin lymphoma--results of the UK HD3 relapse treatment strategy.Ananth Shankar et al.British journal of haematology, 165(4), 534-544 (2014-04-24) A sequential testing approach to detecting multiple change points in the proportional hazards model.Pei He et al.Statistics in medicine, 32(7), 1239-1245 (2012-08-31) A nanoparticle carrying the p53 gene targets tumors including cancer stem cells, sensitizes glioblastoma to chemotherapy and improves survival.Sang-Soo Kim et al.ACS nano, 8(6), 5494-5514 (2014-05-09) 1,3-Bis(2-chloroethyl)-1-nitrosourea as thiol-carbamoylating agent in biological systems.K Becker et al.Methods in enzymology, 251, 173-188 (1995-01-01) Mapping the Human Kinome in Response to DNA Damage.Michel Owusu et al.Cell reports, 26(3), 555-563 (2019-01-17) Sixteenth biannual report of the Cochrane Haematological Malignancies Group: focus on Non-Hodgkin's lymphoma.Michaela Rancea et al.Journal of the National Cancer Institute, 106(8), doi:10-doi:10 (2014-07-18) Establishing the efficacy of Gliadel wafers: progress towards a Phase III trial.Colin Watts et al.Acta neurochirurgica, 155(1), 61-62 (2012-10-31) Cerebral radiation necrosis: a review of the pathobiology, diagnosis and management considerations.Gazanfar Rahmathulla et al.Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 20(4), 485-502 (2013-02-19) Cerebrospinal fluid leak during treatment with bevacizumab and irinotecan after carmustine-impregnated wafers placement in patients with grade 2 oligodendroglioma and glioblastoma multiforme: report of two cases and review of literature.Govardhanan Nagaiah et al.Cancer investigation, 28(10), 1048-1053 (2010-09-30) The sequential use of carmustine wafers (Gliadel®) and post-operative radiotherapy with concomitant temozolomide followed by adjuvant temozolomide: a clinical review.Sanjay Dixit et al.British journal of neurosurgery, 25(4), 459-469 (2011-02-25)

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