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Peer-Reviewed Papers

Pyruvate:ferredoxin oxidoreductase and thioredoxin reductase are involved in 5-nitroimidazole activation while flavin metabolism is linked to 5-nitroimidazole resistance in Giardia lamblia.David Leitsch et al.The Journal of antimicrobial chemotherapy, 66(8), 1756-1765 (2011-05-24) Sequential regimens for Helicobacter pylori eradication.Paul Moayyedi Lancet (London, England), 370(9592), 1010-1012 (2007-09-25) Synthesis of some N-substituted nitroimidazole derivatives as potential antioxidant and antifungal agents.Dorota Olender et al.European journal of medicinal chemistry, 44(2), 645-652 (2008-07-02) [Short - term combined 5-nitroimidazole treatment in vaginal dysbacteriosis with dominant anaerobic species].S Kovachev et al.Akusherstvo i ginekologiia, 50(3), 30-36 (2011-09-16) Structural basis of 5-nitroimidazole antibiotic resistance: the crystal structure of NimA from Deinococcus radiodurans.Hanna-Kirsti S Leiros et al.The Journal of biological chemistry, 279(53), 55840-55849 (2004-10-20) Cationic nucleoside lipids derived from universal bases: A rational approach for siRNA transfection.Claire Ceballos et al.Bioconjugate chemistry, 21(6), 1062-1069 (2010-05-21) A new-generation 5-nitroimidazole can induce highly metronidazole-resistant Giardia lamblia in vitro.Linda A Dunn et al.International journal of antimicrobial agents, 36(1), 37-42 (2010-05-12) Lowering of 5-nitroimidazole's mutagenicity: towards optimal antiparasitic pharmacophore.Maxime D Crozet et al.European journal of medicinal chemistry, 44(2), 653-659 (2008-07-02) Probing NMR parameters, structure and dynamics of 5-nitroimidazole derivatives. Density functional study of prototypical radiosensitizers.Teodorico C Ramalho et al.Magnetic resonance in chemistry : MRC, 43(2), 139-146 (2004-11-24) Heterocyclic compounds as catalysts in the peroxyoxalate chemiluminescence reaction of bis (2, 4, 6-trichlorophenyl) oxalate.Jonsson T and Irgum K. Analytica Chimica Acta, 361(3), 205-215 (1998) Binding of imidazole, 1-methylimidazole and 4-nitroimidazole to yeast cytochrome c peroxidase (CcP) and the distal histidine mutant, CcP(H52L).James E Erman et al.Biochimica et biophysica acta, 1854(8), 869-881 (2015-04-25) Expanded therapeutic potential in activity space of next-generation 5-nitroimidazole antimicrobials with broad structural diversity.Yukiko Miyamoto et al.Proceedings of the National Academy of Sciences of the United States of America, 110(43), 17564-17569 (2013-10-09) Clinical, neuroimaging and pathological features of 5-nitroimidazole-induced encephalo-neuropathy in two patients: Insights into possible pathogenesis.J Chacko et al.Neurology India, 59(5), 743-747 (2011-10-25) Synthesis, in vitro and in vivo characterization of two novel 68Ga-labelled 5-nitroimidazole derivatives as potential agents for imaging hypoxia.Soledad Fernández et al.Nuclear medicine and biology, 40(2), 273-279 (2012-12-12) Synthesis and electrochemistry of 2-ethenyl and 2-ethanyl derivatives of 5-nitroimidazole and antimicrobial activity against Giardia lamblia.Carlos A Valdez et al.Journal of medicinal chemistry, 52(13), 4038-4053 (2009-06-02) Synthesis, in vitro and in vivo characterization of novel 99mTc-'4+1'-labeled 5-nitroimidazole derivatives as potential agents for imaging hypoxia.Javier Giglio et al.Nuclear medicine and biology, 39(5), 679-686 (2012-04-27) In vitro resistance to 5-nitroimidazoles and benzimidazoles in Giardia duodenalis: variability and variation in gene expression.Raúl Argüello-García et al.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 9(6), 1057-1064 (2009-06-02) Use of molecularly imprinted solid-phase extraction sorbent for the determination of four 5-nitroimidazoles and three of their metabolites from egg-based samples before tandem LC-ESIMS/MS analysis.Rayane Mohamed et al.Journal of agricultural and food chemistry, 56(10), 3500-3508 (2008-05-07) [Development and use of test systems for the evaluation of sensitivity of Trichomonas vaginalisto preparations of the 5-nitroimidazole and 5-nitrofuran groups].N S Makhlaĭ et al.Zhurnal mikrobiologii, epidemiologii, i immunobiologii, (3)(3), 71-75 (2011-08-04) New synthesis and antiparasitic activity of model 5-aryl-1-methyl-4-nitroimidazoles.Haythem A Saadeh et al.Molecules (Basel, Switzerland), 14(8), 2758-2767 (2009-08-25) Analysis of four 5-nitroimidazoles and their corresponding hydroxylated metabolites in egg, processed egg, and chicken meat by isotope dilution liquid chromatography tandem mass spectrometry.Pascal Mottier et al.Journal of agricultural and food chemistry, 54(6), 2018-2026 (2006-03-16) High throughput screening identified a substituted imidazole as a novel RANK pathway-selective osteoclastogenesis inhibitor.Taosheng Chen et al.Assay and drug development technologies, 4(4), 387-396 (2006-09-02) Two different modes of halogen bonding in two 4-nitroimidazole derivatives.Maciej Kubicki et al.Acta crystallographica. Section C, Crystal structure communications, 63(Pt 8), o454-o457 (2007-08-07) Apolar distal pocket mutants of yeast cytochrome c peroxidase: Binding of imidazole, 1-methylimidazole and 4-nitroimidazole to the triAla, triVal, and triLeu variants.Anil Bidwai et al.Biochimica et biophysica acta, 1854(8), 919-929 (2015-04-23) Influence of ligand denticity on the properties of novel ⁹⁹mTc(I)-carbonyl complexes. Application to the development of radiopharmaceuticals for imaging hypoxic tissue.Soledad Fernández et al.Bioorganic & medicinal chemistry, 20(13), 4040-4048 (2012-06-05) High functionalization of 5-nitro-1H-imidazole derivatives: the TDAE approach.Thierry Juspin et al.Molecules (Basel, Switzerland), 16(8), 6883-6993 (2011-08-16) Synthesis and biological characterisation of novel dithiocarbamate containing 5-nitroimidazole (99m)Tc-complexes as potential agents for targeting hypoxia.Javier Giglio et al.Bioorganic & medicinal chemistry letters, 21(1), 394-397 (2010-11-23) Quantum-chemical studies on thermodynamic feasibility of 1-methyl-2,4,5-trinitroimidazole processes.Pandurang M Jadhav et al.Journal of molecular modeling, 19(8), 3027-3033 (2013-04-12) Diffuse alveolar haemorrhage due to 5-nitroimidazole treatment.Meral Uyar et al.Respirology (Carlton, Vic.), 14(4), 612-613 (2009-08-04) Antimicrobials that affect the synthesis and conformation of nucleic acids.E Cambau et al.Revue scientifique et technique (International Office of Epizootics), 31(1), 77-87 (2012-08-02)

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