Boiling point	77-78 ºC (19 mmHg)
Flash point	67 ºC
Density	1.89
Refractive index	1.583-1.585

Symbol(GHS)	Xi
Hazard Codes	R36/37/38
SDS/MSDS	S26;S37/39

Source	SDS/MSDS Samples
Alfa-Aesar	View & Download
Sigma-Aldrich	View & Download
Acros-Organics	View & Download

Synthetic Route

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Articles

Peer-Reviewed Papers

In silico insight into voltage-gated sodium channel 1.7 inhibition for anti-pain drug discovery.Mingxing Wang et al.Journal of molecular graphics & modelling, 84, 18-28 (2018-05-25) Synthesis, Biological Evaluation and QSAR Studies of Newer Isoxazole Derivatives.Sahaya Asirvatham et al.Anti-inflammatory & anti-allergy agents in medicinal chemistry, 14(2), 128-137 (2015-08-13) Time-Resolved Photoelectron Spectroscopy Studies of Isoxazole and Oxazole.Ting Geng et al.The journal of physical chemistry. A, 124(20), 3984-3992 (2020-04-04) D-Cycloserine destruction by alanine racemase and the limit of irreversible inhibition.Cesira de Chiara et al.Nature chemical biology, 16(6), 686-694 (2020-03-24) Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules.Sebastian Markmiller et al.Cell, 172(3), 590-604 (2018-01-27) Switchable Synthesis of Pyrroles and Pyrazines via Rh(II)-Catalyzed Reaction of 1,2,3-Triazoles with Isoxazoles: Experimental and DFT Evidence for the 1,4-Diazahexatriene Intermediate.Nikolai V Rostovskii et al.The Journal of organic chemistry, 82(1), 256-268 (2016-12-16) BET bromodomain ligands: Probing the WPF shelf to improve BRD4 bromodomain affinity and metabolic stability.Laura E Jennings et al.Bioorganic & medicinal chemistry, 26(11), 2937-2957 (2018-05-20) Deprotonation of Isoxazole: A Photoelectron Imaging Study.Adam A Wallace et al.The journal of physical chemistry. A, 124(38), 7768-7775 (2020-08-28) Microwave accelerated synthesis of isoxazole hydrazide inhibitors of the system xc- transporter: Initial homology model.Afnan A Matti et al.Bioorganic & medicinal chemistry letters, 23(21), 5931-5935 (2013-09-18) Phase separation of ligand-activated enhancers licenses cooperative chromosomal enhancer assembly.Sreejith J Nair et al.Nature structural & molecular biology, 26(3), 193-203 (2019-03-06) Pro-apoptotic activity of novel synthetic isoxazole derivatives exhibiting inhibitory activity against tumor cell growth in vitro.Ilaria Lampronti et al.Oncology letters, 20(5), 151-151 (2020-09-17) Sea Urchin Embryo Model As a Reliable in Vivo Phenotypic Screen to Characterize Selective Antimitotic Molecules. Comparative evaluation of Combretapyrazoles, -isoxazoles, -1,2,3-triazoles, and -pyrroles as Tubulin-Binding Agents.Marina N Semenova et al.ACS combinatorial science, 20(12), 700-721 (2018-11-20) Farnesoid X Receptor Agonists as Therapeutic Target for Cardiometabolic Diseases.Chao Li et al.Frontiers in pharmacology, 11, 1247-1247 (2020-09-29) Isoxazoles: synthesis, evaluation and bioinformatic design as acetylcholinesterase inhibitors.Margarita Gutiérrez et al.The Journal of pharmacy and pharmacology, 65(12), 1796-1804 (2013-11-05) Ultrafast photodegradation of isoxazole and isothiazolinones by UV254 and UV254/H2O2 photolysis in a microcapillary reactor.Danilo Russo et al.Water research, 169, 115203-115203 (2019-11-02) Selective Mediator dependence of cell-type-specifying transcription.Martin G Jaeger et al.Nature genetics, 52(7), 719-727 (2020-06-03) Development and evaluation of small peptidomimetic ligands to protease-activated receptor-2 (PAR2) through the use of lipid tethering.Scott Boitano et al.PloS one, 9(6), e99140-e99140 (2014-06-14)

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