Melting point	223-225 ºC
Density	1.736

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Source	SDS/MSDS Samples
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Peer-Reviewed Papers

Supersaturatable formulations for the enhanced oral absorption of sirolimus.Min-Soo Kim et al.International journal of pharmaceutics, 445(1-2), 108-116 (2013-02-12) Tocopheryl Polyethylene Glycol Succinate as a Safe, Antioxidant Surfactant for Processing Carbon Nanotubes and Fullerenes.Aihui Yan et al.Carbon, 45(13), 2463-2470 (2008-12-17) BRG1 Loss Predisposes Lung Cancers to Replicative Stress and ATR Dependency.Manav Gupta et al.Cancer research, 80(18), 3841-3854 (2020-07-22) Simultaneous inhibition of metastasis and growth of breast cancer by co-delivery of twist shRNA and paclitaxel using pluronic P85-PEI/TPGS complex nanoparticles.Jianan Shen et al.Biomaterials, 34(5), 1581-1590 (2012-11-14) Efficacy of fat-soluble vitamin supplementation in infants with biliary atresia.Benjamin L Shneider et al.Pediatrics, 130(3), e607-e614 (2012-08-15) Protective effects of vitamin E forms (alpha-tocopherol, gamma-tocopherol and d-alpha-tocopherol polyethylene glycol 1000 succinate) on retinal edema during ischemia-reperfusion injury in the guinea pig retina.Orhan Aydemir et al.International ophthalmology, 25(5-6), 283-289 (2006-03-15) Targeted co-delivery of docetaxel and siPlk1 by herceptin-conjugated vitamin E TPGS based immunomicelles.Jing Zhao et al.Biomaterials, 34(13), 3411-3421 (2013-02-05) Cyclooxygenase-2/prostaglandin E₂ inducing effects of α-tocopheryl polyethylene glycol succinate in lung epithelial cells.Eun-Hye Lee et al.Archives of pharmacal research, 35(9), 1639-1644 (2012-10-12) A new function of Vitamin E-TPGS in the intestinal lymphatic transport of lipophilic drugs: enhancing the secretion of chylomicrons.Zhuoyang Fan et al.International journal of pharmaceutics, 445(1-2), 141-147 (2013-02-12) D-alpha-tocopheryl polyethylene glycol succinate (TPGS) induces cell cycle arrest and apoptosis selectively in Survivin-overexpressing breast cancer cells.Christiana M Neophytou et al.Biochemical pharmacology, 89(1), 31-42 (2014-02-25) Tocopheryl Polyethylene Glycol Succinate as a Safe, Antioxidant Surfactant for Processing Carbon Nanotubes and Fullerenes.Aihui Yan et al.Carbon, 45(13), 2463-2470 (2008-12-17) The effects of topical coenzyme Q10 and vitamin E D-α-tocopheryl polyethylene glycol 1000 succinate after cataract surgery: a clinical and in vivo confocal study.Paolo Fogagnolo et al.Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 229(1), 26-31 (2012-09-27) Increased absorption of mangiferin in the gastrointestinal tract and its mechanism of action by absorption enhancers in rats.Xiaoli Wang et al.Drug development and industrial pharmacy, 39(9), 1408-1413 (2012-07-24) Formulation, antileukemia mechanism, pharmacokinetics, and biodistribution of a novel liposomal emodin.Tiechuang Wang et al.International journal of nanomedicine, 7, 2325-2337 (2012-06-05) Alpha-tocopheryl polyethylene glycol succinate-emulsified poly(lactic-co-glycolic acid) nanoparticles for reversal of multidrug resistance in vitro.Ying Wang et al.Nanotechnology, 23(49), 495103-495103 (2012-11-15) Optimization of formulation and process parameters for the production of nanosuspension by wet media milling technique: effect of Vitamin E TPGS and nanocrystal particle size on oral absorption.Indrajit Ghosh et al.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 47(4), 718-728 (2012-09-04) Synergistic inhibition of breast cancer metastasis by silibinin-loaded lipid nanoparticles containing TPGS.Pengfei Xu et al.International journal of pharmaceutics, 454(1), 21-30 (2013-07-09) Novel lipid based oral formulation of curcumin: development and optimization by design of experiments approach.Yogesh B Pawar et al.International journal of pharmaceutics, 436(1-2), 617-623 (2012-07-31) Enhanced solubility and oral absorption of sirolimus using D-α-tocopheryl polyethylene glycol succinate micelles.Min-Soo Kim et al.Artificial cells, nanomedicine, and biotechnology, 41(2), 85-91 (2013-01-12) Vitamin E D-α-tocopheryl polyethylene glycol 1000 succinate-based nanomedicine.Zhiping Zhang et al.Nanomedicine (London, England), 7(11), 1645-1647 (2012-12-06) Controlled preparation and antitumor efficacy of vitamin E TPGS-functionalized PLGA nanoparticles for delivery of paclitaxel.Guoying Wang et al.International journal of pharmaceutics, 446(1-2), 24-33 (2013-02-14) Fabrication, detection, and analysis of DNA-labeled PLGA particles for environmental transport studies.Coy P McNew et al.Journal of colloid and interface science, 526, 207-219 (2018-05-08) Excitation of GABAergic Neurons in the Bed Nucleus of the Stria Terminalis Triggers Immediate Transition from Non-Rapid Eye Movement Sleep to Wakefulness in Mice.Shota Kodani et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 37(30), 7164-7176 (2017-06-24) Drug "supersaturation" states induced by polymeric micelles and liposomes: a mechanistic investigation into permeability enhancements.Massimiliano di Cagno et al.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 48(4-5), 775-780 (2013-01-29) Trastuzumab-conjugated vitamin E TPGS liposomes for sustained and targeted delivery of docetaxel.Anandhkumar Raju et al.Expert opinion on drug delivery, 10(6), 747-760 (2013-03-06) Enhancement of corneal permeation of riboflavin-5'-phosphate through vitamin E TPGS: a promising approach in corneal trans-epithelial cross linking treatment.Carmine Ostacolo et al.International journal of pharmaceutics, 440(2), 148-153 (2012-10-11) Formulation and in vitro evaluation of quercetin loaded polymeric micelles composed of pluronic P123 and D-a-tocopheryl polyethylene glycol succinate.Liyan Zhao et al.Journal of biomedical nanotechnology, 7(3), 358-365 (2011-08-13) Processing challenges with solid dosage formulations containing vitamin E TPGS.Preetanshu Pandey et al.Pharmaceutical development and technology, 18(1), 296-304 (2012-11-10) Synthesis, characterization, and in-vitro antitumor activity of the polyethylene glycol (350 and 1000) succinate derivatives of the tocopherol and tocotrienol isomers of Vitamin EAbu-Fayyad A and Nazzal S International Journal of Pharmaceutics, 519(1-2), 145-156 (2017) Superparamagnetic iron oxide--loaded poly(lactic acid)-D-alpha-tocopherol polyethylene glycol 1000 succinate copolymer nanoparticles as MRI contrast agent.Chandrasekharan Prashant et al.Biomaterials, 31(21), 5588-5597 (2010-05-04) Intravitreal administration of dexamethasone-loaded PLGA-TPGS nanoparticles for the treatment of posterior segment diseases.Chenming Yang et al.Journal of biomedical nanotechnology, 9(9), 1617-1623 (2013-08-29) Induction of an endogenous B-tropic type C RNA virus from SWR/J mouse embryo cells in tissue culture.J R Stephenson et al.Virology, 70(2), 352-359 (1976-04-01) A novel drug-phospholipid complex loaded micelle for baohuoside I enhanced oral absorption: in vivo and in vivo evaluations.Xin Jin et al.Drug development and industrial pharmacy, 39(9), 1421-1430 (2012-10-13) Micelles of TPGS modified apigenin phospholipid complex for oral administration: preparation, in vitro and in vivo evaluation.Were L L Munyendo et al.Journal of biomedical nanotechnology, 9(12), 2034-2047 (2013-11-26) Identifying the correlation between drug/stabilizer properties and critical quality attributes (CQAs) of nanosuspension formulation prepared by wet media milling technology.Maya George et al.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 48(1-2), 142-152 (2012-10-23) Co-delivery of paclitaxel and survivin shRNA by pluronic P85-PEI/TPGS complex nanoparticles to overcome drug resistance in lung cancer.Jianan Shen et al.Biomaterials, 33(33), 8613-8624 (2012-08-23) Development of curcumin nanocrystal: physical aspects.Heni Rachmawati et al.Journal of pharmaceutical sciences, 102(1), 204-214 (2012-10-11) Vitamin E TPGS prodrug micelles for hydrophilic drug delivery with neuroprotective effects.Yu Mi et al.International journal of pharmaceutics, 438(1-2), 98-106 (2012-09-08) Monitoring the dissolution of Active Pharmaceutical Ingredient and TPGS in real time via IR spectroscopy during the manufacturing of liquid dosage formulation.Slobodan Šašić et al.Journal of pharmaceutical and biomedical analysis, 70, 273-279 (2012-08-09) Pharmacokinetics and tissue distribution of amphotericin B following oral administration of three lipid-based formulations to rats.Fady Ibrahim et al.Drug development and industrial pharmacy, 39(9), 1277-1283 (2012-09-20) Polymeric mixed micelles for delivery of curcumin to multidrug resistant ovarian cancer.Vipin Saxena et al.Journal of biomedical nanotechnology, 9(7), 1146-1154 (2013-08-06)

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