Boiling point	100-104 ºC (15 mmHg)
Flash point	93 ºC
Density	1.4498
Refractive index	1.534

Symbol(GHS)	Xn;N
Hazard Codes	R22;R51/53
SDS/MSDS	S61

Source	SDS/MSDS Samples
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Apollo	View & Download

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Peer-Reviewed Papers

S-nitrosation impairs KLF4 activity and instigates endothelial dysfunction in pulmonary arterial hypertension.Yiqian Ban et al.Redox biology, 21, 101099-101099 (2019-01-20) Oxidant sensor in the cGMP-binding pocket of PKGIα regulates nitroxyl-mediated kinase activity.Sonia Donzelli et al.Scientific reports, 7(1), 9938-9938 (2017-09-01) Prefrontal cholinergic mechanisms instigating shifts from monitoring for cues to cue-guided performance: converging electrochemical and fMRI evidence from rats and humans.William M Howe et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(20), 8742-8752 (2013-05-17) Proteinase activated receptor-2 counterbalances the vascular effects of endothelin-1 in fibrotic tight-skin mice.Fiorentina Roviezzo et al.British journal of pharmacology, 174(22), 4032-4042 (2016-09-15) Fluoxetine oral treatment discloses 5-HT1D receptor as vagoinhibitor of the cardiac cholinergic neurotransmission in rat.Cristina López et al.Canadian journal of physiology and pharmacology, 97(2), 90-98 (2018-11-22) Involvement of Hydrogen Sulfide in Endothelium-Derived Relaxing Factor-Mediated Responses in Rat Cerebral Arteries.Mei Wang et al.Journal of vascular research, 53(3-4), 172-185 (2016-10-13) Activation of presynaptic GABA(B(1a,2)) receptors inhibits synaptic transmission at mammalian inhibitory cholinergic olivocochlear-hair cell synapses.Carolina Wedemeyer et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(39), 15477-15487 (2013-09-27) The comprehensive immunomodulation of NeurimmiRs in haemocytes of oyster Crassostrea gigas after acetylcholine and norepinephrine stimulation.Hao Chen et al.BMC genomics, 16, 942-942 (2015-11-19) Endochondral Ossification Is Accelerated in Cholinesterase-Deficient Mice and in Avian Mesenchymal Micromass Cultures.Janine Spieker et al.PloS one, 12(1), e0170252-e0170252 (2017-01-25) Analysis of the vascular responses in a murine model of polycystic ovary syndrome.Sieneke Labruijere et al.The Journal of endocrinology, 218(2), 205-213 (2013-06-05) Phosphocholine-Modified Macromolecules and Canonical Nicotinic Agonists Inhibit ATP-Induced IL-1β Release.Andreas Hecker et al.Journal of immunology (Baltimore, Md. : 1950), 195(5), 2325-2334 (2015-07-24) Role of aromatase in sex-specific cerebrovascular endothelial function in mice.Kristen L Zuloaga et al.American journal of physiology. Heart and circulatory physiology, 306(7), H929-H937 (2014-02-11) Comparison of the in vitro pharmacological profiles of long-acting muscarinic antagonists in human bronchus.Emmanuel Naline et al.Pulmonary pharmacology & therapeutics, 49, 46-53 (2018-01-18) γ-Acetylcholine Receptor Mediating Dynamic Changes of Resistance to Rocuronium in the Denervated Skeletal Muscle.Hong Wang et al.Pharmacology, 102(3-4), 190-195 (2018-08-14) Synaptic Activity and Muscle Contraction Increases PDK1 and PKCβI Phosphorylation in the Presynaptic Membrane of the Neuromuscular Junction.Erica Hurtado et al.Frontiers in molecular neuroscience, 10, 270-270 (2017-09-12) In vivo and in vitro effects of neostigmine on gastrointestinal tract motility of horses.Jorge E Nieto et al.American journal of veterinary research, 74(4), 579-588 (2013-03-28) Acetyl- and butyryl-cholinesterase inhibitory activities of the edible brown alga Eisenia bicyclis.Jae Sue Choi et al.Archives of pharmacal research, 38(8), 1477-1487 (2014-11-06) Galantamine is not a positive allosteric modulator of human α4β2 or α7 nicotinic acetylcholine receptors.Natalia M Kowal et al.British journal of pharmacology, 175(14), 2911-2925 (2018-04-19) Synergistic effect of tanshinone IIA and mesenchymal stem cells on preventing learning and memory deficits via anti-apoptosis, attenuating tau phosphorylation and enhancing the activity of central cholinergic system in vascular dementia.Deyan Kong et al.Neuroscience letters, 637, 175-181 (2016-11-16) Revealing of T-type low-voltage activated calcium channels (CaV3) in frog neuromuscular junctions.L F Nurullin et al.Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections, 449, 73-75 (2013-05-09) Gingerol Inhibits Serum-Induced Vascular Smooth Muscle Cell Proliferation and Injury-Induced Neointimal Hyperplasia by Suppressing p38 MAPK Activation.Manish Jain et al.Journal of cardiovascular pharmacology and therapeutics, 21(2), 187-200 (2015-08-05) Molecular Mechanisms of Action of M5 Muscarinic Acetylcholine Receptor Allosteric Modulators.Alice E Berizzi et al.Molecular pharmacology, 90(4), 427-436 (2016-07-28) A novel acetylcholine bioensor and its electrochemical behavior.Wei Wang et al.Journal of biomedical nanotechnology, 9(4), 736-740 (2013-04-30) Muscarinic receptors modulate dendrodendritic inhibitory synapses to sculpt glomerular output.Shaolin Liu et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(14), 5680-5692 (2015-04-10) Decrease in neuronal nicotinic acetylcholine receptor subunit and PSD-93 transcript levels in the male mouse MPG after cavernous nerve injury or explant culture.Beatrice M Girard et al.American journal of physiology. Renal physiology, 305(10), F1504-F1512 (2013-09-21) Successful implantation of an engineered tubular neuromuscular tissue composed of human cells and chitosan scaffold.Elie Zakhem et al.Surgery, 158(6), 1598-1608 (2015-06-23) Effects of total flavones from Dendranthema morifolium on vasocontraction and proliferation of vascular smooth muscle cells.Hong-Feng Jin et al.Molecular medicine reports, 13(1), 989-993 (2015-12-10) VEGF-A and VEGF-B Coordinate the Arteriogenesis to Repair the Infarcted Heart with Vagus Nerve Stimulation.Yan-Xia Lv et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 48(2), 433-449 (2018-07-18) Loss of M1 Receptor Dependent Cholinergic Excitation Contributes to mPFC Deactivation in Neuropathic Pain.Daniel Radzicki et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 37(9), 2292-2304 (2017-02-01) Profiling neurotransmitters in a crustacean neural circuit for locomotion.Anna C Schneider et al.PloS one, 13(5), e0197781-e0197781 (2018-05-23) Depressed excitability and ion currents linked to slow exocytotic fusion pore in chromaffin cells of the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.Enrique Calvo-Gallardo et al.American journal of physiology. Cell physiology, 308(1), C1-19 (2014-11-08) Electroencephalographic coherence and cortical acetylcholine during ketamine-induced unconsciousness.D Pal et al.British journal of anaesthesia, 114(6), 979-989 (2015-05-09) Endothelium-dependent and independent vasorelaxant effects of aqueous extract of Tridax procumbens Lin. leaf in rat aortic rings.Hussein M Salahdeen et al.Indian journal of experimental biology, 50(12), 883-888 (2013-08-31) Endothelial Connexin37 and Connexin40 participate in basal but not agonist-induced NO release.Merlijn J Meens et al.Cell communication and signaling : CCS, 13, 34-34 (2015-07-23) Effects of exercise training on stress-induced vascular reactivity alterations: role of nitric oxide and prostanoids.Thiago Bruder-Nascimento et al.Brazilian journal of physical therapy, 19(3), 177-185 (2015-06-18) Ginsenosides Rg5 and Rk1 Enriched Cultured Wild Ginseng Root Extract Bioconversion of Pediococcus pentosaceus HLJG0702: Effect on Scopolamine-Induced Memory Dysfunction in Mice.Kyu Sup An et al.Nutrients, 11(5) (2019-05-30) Acetylcholine protects mesenteric arteries against hypoxia/reoxygenation injury via inhibiting calcium-sensing receptor.Ming Zhao et al.Journal of pharmacological sciences, 127(4), 481-488 (2015-04-30) Diversity of the intestinal microbiota differently affects non-neuronal and atropine-sensitive ileal contractile responses to short-chain fatty acids in mice.Masako Yajima et al.Biomedical research (Tokyo, Japan), 37(5), 319-328 (2016-10-28) CGRP signalling inhibits NO production through pannexin-1 channel activation in endothelial cells.Pablo S Gaete et al.Scientific reports, 9(1), 7932-7932 (2019-05-30) The Restorative Effects of Eucommia ulmoides Oliver Leaf Extract on Vascular Function in Spontaneously Hypertensive Rats.Shingo Hosoo et al.Molecules (Basel, Switzerland), 20(12), 21971-21981 (2015-12-23) Acute Treatment with Lauric Acid Reduces Blood Pressure and Oxidative Stress in Spontaneously Hypertensive Rats.Naiane Ferraz Bandeira Alves et al.Basic & clinical pharmacology & toxicology, 120(4), 348-353 (2017-01-06) Endothelium-dependent vasodilatory signalling modulates α1 -adrenergic vasoconstriction in contracting skeletal muscle of humans.Christopher M Hearon et al.The Journal of physiology, 594(24), 7435-7453 (2016-11-05) Impact of serum lipoprotein(a) on endothelium-dependent coronary vasomotor response assessed by intracoronary acetylcholine provocation.Ahmed Mashaly et al.Coronary artery disease, 29(6), 516-525 (2018-06-19) Cholinergic control over attention in rats prone to attribute incentive salience to reward cues.Giovanna Paolone et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(19), 8321-8335 (2013-05-10) GelRed/[GJie-Qiong Chen et al.Biosensors & bioelectronics, 100, 526-532 (2017-10-11) Crosstalk between mAChRM3 and β2AR, via acetylcholine PI3/PKC/PBEP1/Raf-1 MEK1/2/ERK1/2 pathway activation, in human bronchial epithelial cells after long-term cigarette smoke exposure.Giusy Daniela Albano et al.Life sciences, 192, 99-109 (2017-11-28) Pesticide analysis using nanoceria-coated paper-based devices as a detection platform.Souksanh Nouanthavong et al.The Analyst, 141(5), 1837-1846 (2016-02-05) Beneficial Effect of the Nitric Oxide Donor Compound 3-(1,3-Dioxoisoindolin-2-yl)Benzyl Nitrate on Dysregulated Phosphodiesterase 5, NADPH Oxidase, and Nitrosative Stress in the Sickle Cell Mouse Penis: Implication for Priapism Treatment.Fábio H Silva et al.The Journal of pharmacology and experimental therapeutics, 359(2), 230-237 (2016-08-20) The vasorelaxant mechanisms of methanol on isolated rat aortic rings: Involvement of ion channels and signal transduction pathways.Y Bai et al.Human & experimental toxicology, 36(10), 1031-1038 (2016-11-18) Deciphering the mechanism of Huang-Lian-Jie-Du-Decoction on the treatment of sepsis by formula decomposition and metabolomics: Enhancement of cholinergic pathways and inhibition of HMGB-1/TLR4/NF-κB signaling.Dingqiao Xu et al.Pharmacological research, 121, 94-113 (2017-04-25) Fast modulation of visual perception by basal forebrain cholinergic neurons.Lucas Pinto et al.Nature neuroscience, 16(12), 1857-1863 (2013-10-29) Hydrogen peroxide and nitric oxide induce anticontractile effect of perivascular adipose tissue via renin angiotensin system activation.Natália Nóbrega et al.Nitric oxide : biology and chemistry, 84, 50-59 (2019-01-07) Alkaloids from Nelumbinis Plumula (AFNP) ameliorate aortic remodeling via RhoA/ROCK pathway.Qiongyu Li et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 112, 108651-108651 (2019-02-21) A1-adenosine acute withdrawal response and cholecystokinin-8 induced contractures are regulated by Ca(2+)- and ATP-activated K(+) channels.Maria Grazia Cascio et al.Pharmacological research, 95-96, 82-91 (2015-04-04) Mechanisms underlying the vasorelaxant effect of trans-4-methoxy-β-nitrostyrene in the rat mesenteric resistance arteries.Thayane Rebeca Alves-Santos et al.European journal of pharmacology, 853, 201-209 (2019-02-05) Cardioprotection Induced by Activation of GPER in Ovariectomized Rats With Pulmonary Hypertension.Allan K N Alencar et al.The journals of gerontology. Series A, Biological sciences and medical sciences, 73(9), 1158-1166 (2018-05-24) Inhibitory evaluation of oligonol on α-glucosidase, protein tyrosine phosphatase 1B, cholinesterase, and β-secretase 1 related to diabetes and Alzheimer's disease.Jae Sue Choi et al.Archives of pharmacal research, 39(3), 409-420 (2016-01-05) Acetylcholine-related proteins in non-neoplastic appearing colonic mucosa from patients with colorectal neoplasia.Morten Matthiesen Bach Damm et al.Molecular carcinogenesis, 56(10), 2223-2233 (2017-05-26) Skeletal muscle calpain acts through nitric oxide and neural miRNAs to regulate acetylcholine release in motor nerve terminals.Haipeng Zhu et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(17), 7308-7324 (2013-04-26) Differential modulation of spontaneous and evoked thalamocortical network activity by acetylcholine level in vitro.Jason C Wester et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(45), 17951-17966 (2013-11-08) Mechanisms underlying the vasorelaxant effect of trans-4-methoxy-β-nitrostyrene in the rat mesenteric resistance arteries.Thayane Rebeca Alves-Santos et al.European journal of pharmacology, 853, 201-209 (2019-02-05) Cardioprotection Induced by Activation of GPER in Ovariectomized Rats With Pulmonary Hypertension.Allan K N Alencar et al.The journals of gerontology. Series A, Biological sciences and medical sciences, 73(9), 1158-1166 (2018-05-24) Hydrogen peroxide and nitric oxide induce anticontractile effect of perivascular adipose tissue via renin angiotensin system activation.Natália Nóbrega et al.Nitric oxide : biology and chemistry, 84, 50-59 (2019-01-07) Alkaloids from Nelumbinis Plumula (AFNP) ameliorate aortic remodeling via RhoA/ROCK pathway.Qiongyu Li et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 112, 108651-108651 (2019-02-21) Physiologically-Based Pharmacokinetic and Pharmacodynamic Modeling for the Inhibition of Acetylcholinesterase by Acotiamide, A Novel Gastroprokinetic Agent for the Treatment of Functional Dyspepsia, in Rat Stomach.Kazuyoshi Yoshii et al.Pharmaceutical research, 33(2), 292-300 (2015-09-10) Beneficial Effect of the Nitric Oxide Donor Compound 3-(1,3-Dioxoisoindolin-2-yl)Benzyl Nitrate on Dysregulated Phosphodiesterase 5, NADPH Oxidase, and Nitrosative Stress in the Sickle Cell Mouse Penis: Implication for Priapism Treatment.Fábio H Silva et al.The Journal of pharmacology and experimental therapeutics, 359(2), 230-237 (2016-08-20) The vasorelaxant mechanisms of methanol on isolated rat aortic rings: Involvement of ion channels and signal transduction pathways.Y Bai et al.Human & experimental toxicology, 36(10), 1031-1038 (2016-11-18) Deciphering the mechanism of Huang-Lian-Jie-Du-Decoction on the treatment of sepsis by formula decomposition and metabolomics: Enhancement of cholinergic pathways and inhibition of HMGB-1/TLR4/NF-κB signaling.Dingqiao Xu et al.Pharmacological research, 121, 94-113 (2017-04-25) Fast modulation of visual perception by basal forebrain cholinergic neurons.Lucas Pinto et al.Nature neuroscience, 16(12), 1857-1863 (2013-10-29) Salidroside improves endothelial function and alleviates atherosclerosis by activating a mitochondria-related AMPK/PI3K/Akt/eNOS pathway.Sha-Sha Xing et al.Vascular pharmacology, 72, 141-152 (2015-07-19) The effects of anti-obesity intervention with orlistat and sibutramine on microvascular endothelial function.Belqes Abdullah Mohammad Al-Tahami et al.Clinical hemorheology and microcirculation, 59(4), 323-334 (2013-09-05) Impaired short- and long-latency afferent inhibition in amyotrophic lateral sclerosis.Bülent Cengiz et al.Muscle & nerve, 59(6), 699-704 (2019-03-09) PACAP Modulates Acetylcholine-Elicited Contractions at Nicotinic Neuromuscular Contacts of the Land Snail.Nóra Krajcs et al.Journal of molecular neuroscience : MN, 57(4), 492-500 (2015-07-04) Mechanisms Underlying Enhanced Noradrenaline-Induced Femoral Arterial Contractions of Spontaneously Hypertensive Rats: Involvement of Endothelium-Derived Factors and Cyclooxygenase-Derived Prostanoids.Takayuki Matsumoto et al.Biological & pharmaceutical bulletin, 39(3), 384-393 (2016-03-05) Angiotensin-(1-7) induced vascular relaxation in spontaneously hypertensive rats.Feng Zhang et al.Nitric oxide : biology and chemistry, 88, 1-9 (2019-03-19) 6-Phenylpyrimidin-4-ones as Positive Allosteric Modulators at the M1 mAChR: The Determinants of Allosteric Activity.Manuela Jörg et al.ACS chemical neuroscience, 10(3), 1099-1114 (2018-12-15) Arginase upregulation and eNOS uncoupling contribute to impaired endothelium-dependent vasodilation in a rat model of intrauterine growth restriction.Isabelle Grandvuillemin et al.American journal of physiology. Regulatory, integrative and comparative physiology, 315(3), R509-R520 (2018-05-10) Stoichiometry of the Heteromeric Nicotinic Receptors of the Renshaw Cell.Boris Lamotte d'Incamps et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 38(21), 4943-4956 (2018-05-05) Detection of evoked acetylcholine release in mouse brain slices.R Asri et al.The Analyst, 141(23), 6416-6421 (2016-10-11) Exposure to acetaminophen impairs vasodilation, increases oxidative stress and changes arterial morphology of rats.Hellen Karine Paes Porto et al.Archives of toxicology, 93(7), 1955-1964 (2019-04-26) Genetic dissection of the vav2-rac1 signaling axis in vascular smooth muscle cells.Salvatore Fabbiano et al.Molecular and cellular biology, 34(24), 4404-4419 (2014-10-08) Response.Ashbeel Roy et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(1), 2-3 (2014-01-05) The transcription factor Hmx1 and growth factor receptor activities control sympathetic neurons diversification.Alessandro Furlan et al.The EMBO journal, 32(11), 1613-1625 (2013-04-18) Simultaneous monitoring of Ca2+ responses and salivary secretion in live animals reveals a threshold intracellular Ca2+ concentration for salivation.Akihiro Nezu et al.Experimental physiology, 104(1), 61-69 (2018-10-28) Active fragments-guided drug discovery and design of selective tropane alkaloids using ultra-high performance liquid chromatography-quadrupole time-of-flight tandem mass spectrometry coupled with virtual calculation and biological evaluation.Mengge Zhou et al.Analytical and bioanalytical chemistry, 409(4), 1145-1157 (2016-11-01) Recombinant Newcastle disease virus rL-RVG enhances the apoptosis and inhibits the migration of A549 lung adenocarcinoma cells via regulating alpha 7 nicotinic acetylcholine receptors in vitro.Yulan Yan et al.Virology journal, 14(1), 190-190 (2017-10-05) Small and Intermediate Calcium-Activated Potassium Channel Openers Improve Rat Endothelial and Erectile Function.Simon G Comerma-Steffensen et al.Frontiers in pharmacology, 8, 660-660 (2017-10-11) Tetramethylpyrazine reverses intracerebroventricular streptozotocin-induced memory deficits by inhibiting GSK-3β.Fen Lu et al.Acta biochimica et biophysica Sinica, 49(8), 722-728 (2017-06-22) Icariin Improves Cognitive Impairment after Traumatic Brain Injury by Enhancing Hippocampal Acetylation.Zi-Gang Zhang et al.Chinese journal of integrative medicine, 24(5), 366-371 (2018-01-13) The Organophosphorus Pesticide Chlorpyrifos Induces Sex-Specific Airway Hyperreactivity in Adult Rats.Frances C Shaffo et al.Toxicological sciences : an official journal of the Society of Toxicology, 165(1), 244-253 (2018-06-26) Acetylcholine acts through M3 muscarinic receptor to activate the EGFR signaling and promotes gastric cancer cell proliferation.Huangfei Yu et al.Scientific reports, 7, 40802-40802 (2017-01-20) Vasorelaxant properties of Vernonia amygdalina ethanol extract and its possible mechanism.Yung Sing Ch'ng et al.Pharmaceutical biology, 55(1), 2083-2094 (2017-08-24) Involvement of Potassium Channels and Calcium-Independent Mechanisms in Hydrogen Sulfide-Induced Relaxation of Rat Mesenteric Small Arteries.Elise R Hedegaard et al.The Journal of pharmacology and experimental therapeutics, 356(1), 53-63 (2015-10-24) Sodium Tanshinone II-A Sulfonate (DS-201) Induces Vasorelaxation of Rat Mesenteric Arteries via Inhibition of L-Type CaXiao-Dong Zhang et al.Frontiers in pharmacology, 9, 62-62 (2018-02-20) Effects of RMF on BKCa and Kv channels in basilar arterial smooth‑muscle cells of SHR.Yan-Fei Qian et al.Molecular medicine reports, 16(3), 2620-2626 (2017-07-06) Endothelial nitric oxide synthase uncoupling and microvascular dysfunction in the mesentery of mice deficient in α-galactosidase A.Justin J Kang et al.American journal of physiology. Gastrointestinal and liver physiology, 306(2), G140-G146 (2013-11-16) Ikarisoside A inhibits acetylcholine-induced catecholamine secretion and synthesis by suppressing nicotinic acetylcholine receptor-ion channels in cultured bovine adrenal medullary cells.Xiaojia Li et al.Naunyn-Schmiedeberg's archives of pharmacology, 388(12), 1259-1269 (2015-08-11) Abnormalities associated with progressive aortic vascular dysfunction in chronic kidney disease.Omar Z Ameer et al.Frontiers in physiology, 6, 150-150 (2015-06-05) Esculetin ameliorates vascular perturbation by intervening in the occupancy of H2BK120Ub at At1, At2, Tgfβ1 and Mcp1 promoter gene in thoracic aorta of IR and T2D rats.Almesh Kadakol et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 95, 1461-1468 (2017-09-28) In-depth characterization of the neuroinflammatory reaction induced by peripheral surgery in an animal model.Konstanze Plaschke et al.Journal of neural transmission (Vienna, Austria : 1996), 125(10), 1487-1494 (2018-07-25) Eleutheroside E attenuates isoflurane-induced cognitive dysfunction by regulating the α7-nAChR-NMDAR pathway.Xu Lu et al.Neuroreport, 30(3), 188-194 (2018-12-27) Sirt1 inhibits HG-induced endothelial injury: Role of Mff-based mitochondrial fission and F‑actin homeostasis-mediated cellular migration.Ruijie Qin et al.International journal of molecular medicine, 44(1), 89-102 (2019-05-23) [Role of serine/threonine and tyrosine protein phosphatases in command Helix lucorum neurons at the cellular correlate of habituation].A S Pivovarov et al.Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova, 63(2), 256-268 (2013-07-23) The nicotinic α5 subunit can replace either an acetylcholine-binding or nonbinding subunit in the α4β2* neuronal nicotinic receptor.Xiaochun Jin et al.Molecular pharmacology, 85(1), 11-17 (2013-11-05) Conducted dilatation to ATP and KK A Dora Acta physiologica (Oxford, England), 219(1), 202-218 (2016-01-26) Beneficial Effect of Protein Tyrosine Phosphatase Inhibitor and Phytoestrogen in Dyslipidemia-Induced Vascular Dementia in Ovariectomized Rats.Aditi Verma et al.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 24(11), 2434-2446 (2015-09-02) Identification of distinct ChAT⁺ neurons and activity-dependent control of postnatal SVZ neurogenesis.Patricia Paez-Gonzalez et al.Nature neuroscience, 17(7), 934-942 (2014-06-02) In vitro spontaneous contractile activity of colonic smooth muscle in naive Lewis rats: Acute effect of gonadal hormones.Christine Baumgartner et al.Journal of digestive diseases, 18(1), 13-22 (2016-12-23) Muscarinic Acetylcholine Receptors and M-Currents Underlie Efferent-Mediated Slow Excitation in Calyx-Bearing Vestibular Afferents.J Chris Holt et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 37(7), 1873-1887 (2017-01-18) Synchronization in the Heart Rate and the Vasomotion in Rat Aorta: Effect of Arsenic Trioxide.Fredi Cifuentes et al.Cardiovascular toxicology, 16(1), 79-88 (2015-02-11) In vivo evaluation of the antitussive, expectorant and bronchodilating effects of extract and fractions from aerial parts of Peganum harmala linn.Wei Liu et al.Journal of ethnopharmacology, 162, 79-86 (2015-01-06) Protective effect of a sesamin derivative, 3-bis (3-methoxybenzyl) butane-1, 4-diol on Aβ-stressed PC12 cells.Chien-Wei Hou et al.Archives of pharmacal research, 38(4), 543-548 (2014-07-31) Terminalia chebula extract prevents scopolamine-induced amnesia via cholinergic modulation and anti-oxidative effects in mice.Min-Soo Kim et al.BMC complementary and alternative medicine, 18(1), 136-136 (2018-05-03) Eugenol Attenuates Scopolamine-Induced Hippocampal Cholinergic, Glutamatergic, and Mitochondrial Toxicity in Experimental Rats.Debapriya Garabadu et al.Neurotoxicity research, 35(4), 848-859 (2019-02-10) Quantal and non-quantal acetylcholine release at neuromuscular junctions of muscles of different types in a model of hypogravity.O V Tyapkina et al.Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections, 448, 4-6 (2013-03-13) Evaluation of butyrylcholinesterase inhibitory activity by chlorogenic acids and coffee extracts assed in ITC and docking simulation models.Grażyna Budryn et al.Food research international (Ottawa, Ont.), 109, 268-277 (2018-05-29) Nilotinib attenuates endothelial dysfunction and liver damage in high-cholesterol-fed rabbits.D S El-Agamy Human & experimental toxicology, 36(11), 1131-1145 (2016-12-13) Long-term administration of pyridostigmine attenuates pressure overload-induced cardiac hypertrophy by inhibiting calcineurin signalling.Yi Lu et al.Journal of cellular and molecular medicine, 21(9), 2106-2116 (2017-03-16) The impact of exercise frequency upon microvascular endothelium function and oxidative stress among patients with coronary artery disease.Juliana P Borges et al.Clinical physiology and functional imaging, 38(5), 840-846 (2017-12-28) Toll-like receptor 4 contributes to vascular remodelling and endothelial dysfunction in angiotensin II-induced hypertension.R Hernanz et al.British journal of pharmacology, 172(12), 3159-3176 (2015-02-26) Effects of exercise training on stress-induced vascular reactivity alterations: role of nitric oxide and prostanoids.Thiago Bruder-Nascimento et al.Brazilian journal of physical therapy, 19(3), 177-185 (2015-06-18) MicroRNA-21 Contributes to Reduced Microvascular Function in Binge Drinking Young Adults.Jing-Tan Bian et al.Alcoholism, clinical and experimental research, 42(2), 278-285 (2017-11-28) Free energy, precision and learning: the role of cholinergic neuromodulation.Rosalyn J Moran et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(19), 8227-8236 (2013-05-10) Nebivolol suppresses asymmetric dimethylarginine and attenuates cyclosporine-induced nephrotoxicity and endothelial dysfunction in rats.Wafaa A Hewedy et al.Pharmacological reports : PR, 68(6), 1319-1325 (2016-10-05) Vasodilatory effects and underlying mechanisms of the ethyl acetate extracts from Gastrodia elata.Rong Dai et al.Canadian journal of physiology and pharmacology, 95(5), 564-571 (2017-02-09) GPER inhibits diabetes-mediated RhoA activation to prevent vascular endothelial dysfunction.Zilin Li et al.European journal of cell biology, 95(2), 100-113 (2016-01-21) Confirming a Role for α9nAChRs and SK Potassium Channels in Type II Hair Cells of the Turtle Posterior Crista.Xiaorong Xu Parks et al.Frontiers in cellular neuroscience, 11, 356-356 (2017-12-05) Acetylcholine acts through M3 muscarinic receptor to activate the EGFR signaling and promotes gastric cancer cell proliferation.Huangfei Yu et al.Scientific reports, 7, 40802-40802 (2017-01-20) Endothelial nitric oxide synthase uncoupling and microvascular dysfunction in the mesentery of mice deficient in α-galactosidase A.Justin J Kang et al.American journal of physiology. Gastrointestinal and liver physiology, 306(2), G140-G146 (2013-11-16) Impaired capsaicin-induced relaxation in diabetic mesenteric arteries.Yuanyuan Zhang et al.Journal of diabetes and its complications, 29(6), 747-754 (2015-06-10) Ikarisoside A inhibits acetylcholine-induced catecholamine secretion and synthesis by suppressing nicotinic acetylcholine receptor-ion channels in cultured bovine adrenal medullary cells.Xiaojia Li et al.Naunyn-Schmiedeberg's archives of pharmacology, 388(12), 1259-1269 (2015-08-11) Abnormalities associated with progressive aortic vascular dysfunction in chronic kidney disease.Omar Z Ameer et al.Frontiers in physiology, 6, 150-150 (2015-06-05) Involvement of Potassium Channels and Calcium-Independent Mechanisms in Hydrogen Sulfide-Induced Relaxation of Rat Mesenteric Small Arteries.Elise R Hedegaard et al.The Journal of pharmacology and experimental therapeutics, 356(1), 53-63 (2015-10-24) Insufficient sleep is associated with impaired nitric oxide-mediated endothelium-dependent vasodilation.Anthony R Bain et al.Atherosclerosis, 265, 41-46 (2017-08-29) Smooth Muscle Hgs Deficiency Leads to Impaired Esophageal Motility.Jicheng Chen et al.International journal of biological sciences, 11(7), 794-802 (2015-06-17) Eugenol Attenuates Scopolamine-Induced Hippocampal Cholinergic, Glutamatergic, and Mitochondrial Toxicity in Experimental Rats.Debapriya Garabadu et al.Neurotoxicity research, 35(4), 848-859 (2019-02-10) δ-opioid and dopaminergic processes in accumbens shell modulate the cholinergic control of predictive learning and choice.Vincent Laurent et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(4), 1358-1369 (2014-01-24) Quantal and non-quantal acetylcholine release at neuromuscular junctions of muscles of different types in a model of hypogravity.O V Tyapkina et al.Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections, 448, 4-6 (2013-03-13) Sulforaphane Improves Ischemia-Induced Detrusor Overactivity by Downregulating the Enhancement of Associated Endoplasmic Reticulum Stress, Autophagy, and Apoptosis in Rat Bladder.Huai-Ching Tai et al.Scientific reports, 6, 36110-36110 (2016-11-09) Colorimetric biosensor for the assay of paraoxon in environmental water samples based on the iodine-starch color reaction.Liangqia Guo et al.Analytica chimica acta, 967, 59-63 (2017-04-10) Functional Characterization of Novel Circular RNA Molecule, circzip-2 and Its Synthesizing Gene zip-2 in C. elegans Model of Parkinson's Disease.Lalit Kumar et al.Molecular neurobiology, 55(8), 6914-6926 (2018-01-25) Esculetin ameliorates vascular perturbation by intervening in the occupancy of H2BK120Ub at At1, At2, Tgfβ1 and Mcp1 promoter gene in thoracic aorta of IR and T2D rats.Almesh Kadakol et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 95, 1461-1468 (2017-09-28) Toll-like receptor 4 contributes to vascular remodelling and endothelial dysfunction in angiotensin II-induced hypertension.R Hernanz et al.British journal of pharmacology, 172(12), 3159-3176 (2015-02-26) Sirt1 inhibits HG-induced endothelial injury: Role of Mff-based mitochondrial fission and F‑actin homeostasis-mediated cellular migration.Ruijie Qin et al.International journal of molecular medicine, 44(1), 89-102 (2019-05-23) [Role of serine/threonine and tyrosine protein phosphatases in command Helix lucorum neurons at the cellular correlate of habituation].A S Pivovarov et al.Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova, 63(2), 256-268 (2013-07-23) In vitro spontaneous contractile activity of colonic smooth muscle in naive Lewis rats: Acute effect of gonadal hormones.Christine Baumgartner et al.Journal of digestive diseases, 18(1), 13-22 (2016-12-23) Selectivity of coronaridine congeners at nicotinic acetylcholine receptors and inhibitory activity on mouse medial habenula.Hugo R Arias et al.The international journal of biochemistry & cell biology, 92, 202-209 (2017-10-19) In-depth characterization of the neuroinflammatory reaction induced by peripheral surgery in an animal model.Konstanze Plaschke et al.Journal of neural transmission (Vienna, Austria : 1996), 125(10), 1487-1494 (2018-07-25) Eleutheroside E attenuates isoflurane-induced cognitive dysfunction by regulating the α7-nAChR-NMDAR pathway.Xu Lu et al.Neuroreport, 30(3), 188-194 (2018-12-27) Beneficial Effect of Protein Tyrosine Phosphatase Inhibitor and Phytoestrogen in Dyslipidemia-Induced Vascular Dementia in Ovariectomized Rats.Aditi Verma et al.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 24(11), 2434-2446 (2015-09-02) Asthma causes inflammation of human pulmonary arteries and decreases vasodilatation induced by prostaglandin INabil Foudi et al.The Journal of asthma : official journal of the Association for the Care of Asthma, 54(10), 1012-1018 (2017-03-18) Interactions of human butyrylcholinesterase with phenylvalerate and acetylthiocholine as substrates and inhibitors: kinetic and molecular modeling approaches.Jorge Estévez et al.Archives of toxicology, 93(5), 1281-1296 (2019-03-17) Icariin Improves Cognitive Impairment after Traumatic Brain Injury by Enhancing Hippocampal Acetylation.Zi-Gang Zhang et al.Chinese journal of integrative medicine, 24(5), 366-371 (2018-01-13) Extracellular ATP and β-NAD alter electrical properties and cholinergic effects in the rat heart in age-specific manner.Ksenia B Pustovit et al.Purinergic signalling, 15(1), 107-117 (2019-02-14) Expression of Quinone Reductase-2 in the Cortex Is a Muscarinic Acetylcholine Receptor-Dependent Memory Consolidation Constraint.Akiva N Rappaport et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(47), 15568-15581 (2015-11-27) Bedside to bench: role of muscarinic receptor activation in ultrarapid growth of colorectal cancer in a patient with pheochromocytoma.Erik C von Rosenvinge et al.Mayo Clinic proceedings, 88(11), 1340-1346 (2013-10-09) Insufficient sleep is associated with impaired nitric oxide-mediated endothelium-dependent vasodilation.Anthony R Bain et al.Atherosclerosis, 265, 41-46 (2017-08-29) Irisin relaxes mouse mesenteric arteries through endothelium-dependent and endothelium-independent mechanisms.Miao Jiang et al.Biochemical and biophysical research communications, 468(4), 832-836 (2015-11-20) Neuroprotective effect of tanshinone IIA-incubated mesenchymal stem cells on Aβ25-35-induced neuroinflammation.Nanqu Huang et al.Behavioural brain research, 365, 48-55 (2019-03-05) A Novel Immunomodulatory Mechanism Dependent on Acetylcholine Secreted by Human Bone Marrow-derived Mesenchymal Stem Cells.Tac-Ghee Yi et al.International journal of stem cells, 12(2), 315-330 (2019-06-28) Relaxation Induced by Atrial Natriuretic Peptide Is Impaired in Carotid but Not Renal Arteries from Spontaneously Hypertensive Rats Due to Reduced BKCa Channel Activity.Takayuki Matsumoto et al.Biological & pharmaceutical bulletin, 38(11), 1801-1808 (2015-11-03) Myocardial Infarction Causes Transient Cholinergic Transdifferentiation of Cardiac Sympathetic Nerves via gp130.Antoinette Olivas et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 36(2), 479-488 (2016-01-14) Infliximab therapy restores adiponectin expression in perivascular adipose tissue and improves endothelial nitric oxide-mediated vasodilation in mice with type 1 diabetes.Carmela Nacci et al.Vascular pharmacology, 87, 83-91 (2016-08-28) Anagyrine desensitization of peripheral nicotinic acetylcholine receptors. A potential biomarker of quinolizidine alkaloid teratogenesis in cattle.Benedict T Green et al.Research in veterinary science, 115, 195-200 (2017-05-12) Protective effects of choline against hypoxia-induced injuries of vessels and endothelial cells.Lian-Cheng Zhang et al.Experimental and therapeutic medicine, 13(5), 2316-2324 (2017-06-02) Persistent sodium current drives conditional pacemaking in CA1 pyramidal neurons under muscarinic stimulation.Jason Yamada-Hanff et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(38), 15011-15021 (2013-09-21) BACE1 and cholinesterase inhibitory activities of Nelumbo nucifera embryos.Hyun Ah Jung et al.Archives of pharmacal research, 38(6), 1178-1187 (2014-10-11) Smooth Muscle Hgs Deficiency Leads to Impaired Esophageal Motility.Jicheng Chen et al.International journal of biological sciences, 11(7), 794-802 (2015-06-17) δ-opioid and dopaminergic processes in accumbens shell modulate the cholinergic control of predictive learning and choice.Vincent Laurent et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(4), 1358-1369 (2014-01-24) Sulforaphane Improves Ischemia-Induced Detrusor Overactivity by Downregulating the Enhancement of Associated Endoplasmic Reticulum Stress, Autophagy, and Apoptosis in Rat Bladder.Huai-Ching Tai et al.Scientific reports, 6, 36110-36110 (2016-11-09) Functional Characterization of Novel Circular RNA Molecule, circzip-2 and Its Synthesizing Gene zip-2 in C. elegans Model of Parkinson's Disease.Lalit Kumar et al.Molecular neurobiology, 55(8), 6914-6926 (2018-01-25) Activation of muscarinic acetylcholine receptors elevates intracellular Ca(2+) concentrations in accessory lobe neurons of the chick.Keita Takahashi et al.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 201(4), 385-394 (2014-12-08) Liraglutide Improves Renal Endothelial Function in Obese Zucker Rats on a High-Salt Diet.Vijayakumar Sukumaran et al.The Journal of pharmacology and experimental therapeutics, 369(3), 375-388 (2019-03-27) Modulation of nicotinic receptor channels by adrenergic stimulation in rat pinealocytes.Jin-Young Yoon et al.American journal of physiology. Cell physiology, 306(8), C726-C735 (2014-02-21) Anti-atherosclerotic effect of the angiotensin 1-7 mimetic AVE0991 is mediated by inhibition of perivascular and plaque inflammation in early atherosclerosis.D S Skiba et al.British journal of pharmacology, 174(22), 4055-4069 (2016-12-10) Hepatic protein tyrosine phosphatase 1B (PTP1B) deficiency protects against obesity-induced endothelial dysfunction.Abdelali Agouni et al.Biochemical pharmacology, 92(4), 607-617 (2014-12-03) Alpha6-containing nicotinic acetylcholine receptor is a highly sensitive target of alcohol.Fenfei Gao et al.Neuropharmacology, 149, 45-54 (2019-02-03) Cryptic pocket formation underlies allosteric modulator selectivity at muscarinic GPCRs.Scott A Hollingsworth et al.Nature communications, 10(1), 3289-3289 (2019-07-25) Muscarinic M₃ receptors contribute to allergen-induced airway remodeling in mice.Loes E M Kistemaker et al.American journal of respiratory cell and molecular biology, 50(4), 690-698 (2013-10-26) [Ca2+ ] changes in sympathetic varicosities and Schwann cells in rat mesenteric arteries-Relation to noradrenaline release and contraction.Thomas Hansen et al.Acta physiologica (Oxford, England), 226(4), e13279-e13279 (2019-04-09) Spasmolytic Activity of Carvone and Limonene Enantiomers.Damião Pergentino de Sousa et al.Natural product communications, 10(11), 1893-1896 (2016-01-12) Rational Design and Multibiological Profiling of Novel Donepezil-Trolox Hybrids against Alzheimer's Disease, with Cholinergic, Antioxidant, Neuroprotective, and Cognition Enhancing Properties.Pei Cai et al.ACS chemical neuroscience, 8(11), 2496-2511 (2017-08-15) A New Chimeric Natriuretic Peptide, CShu-Miao Zhang et al.Scientific reports, 7(1), 10099-10099 (2017-09-01) Primary hippocampal neuronal cell death induction after acute and repeated paraquat exposures mediated by AChE variants alteration and cholinergic and glutamatergic transmission disruption.Javier Del Pino et al.Toxicology, 390, 88-99 (2017-09-17) Two distinct allosteric binding sites at α4β2 nicotinic acetylcholine receptors revealed by NS206 and NS9283 give unique insights to binding activity-associated linkage at Cys-loop receptors.Jeppe A Olsen et al.The Journal of biological chemistry, 288(50), 35997-36006 (2013-10-31) Colorimetric biosensor for the assay of paraoxon in environmental water samples based on the iodine-starch color reaction.Liangqia Guo et al.Analytica chimica acta, 967, 59-63 (2017-04-10) Orthosteric and/or Allosteric Binding of α-Conotoxins to Nicotinic Acetylcholine Receptors and Their Models.Elena V Kryukova et al.Marine drugs, 16(12) (2018-11-25) Nociceptin reduces the inflammatory immune microenvironment in a conventional murine model of airway hyperresponsiveness.G Spaziano et al.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 47(2), 208-216 (2016-08-27) Targeted Neurotransmitters Profiling Identifies Metabolic Signatures in Rat Brain by LC-MS/MS: Application in Insomnia, Depression and Alzheimer's Disease.Huarong Xu et al.Molecules (Basel, Switzerland), 23(9) (2018-09-20) Is endothelial microvascular function equally impaired among patients with chronic Chagas and ischemic cardiomyopathy?Juliana Pereira Borges et al.International journal of cardiology, 265, 35-37 (2018-05-14) Cholinergic Enhancement of Cell Proliferation in the Postnatal Neurogenic Niche of the Mammalian Spinal Cord.Laura F Corns et al.Stem cells (Dayton, Ohio), 33(9), 2864-2876 (2015-06-04) Selectivity of coronaridine congeners at nicotinic acetylcholine receptors and inhibitory activity on mouse medial habenula.Hugo R Arias et al.The international journal of biochemistry & cell biology, 92, 202-209 (2017-10-19) Na/Ca(2+) exchanger 1 transgenic mice display increased relaxation in the distal colon.Kazuhiro Nishiyama et al.Pharmacology, 94(5-6), 230-238 (2014-11-28) Ergothioneine prevents endothelial dysfunction induced by mercury chloride.Göksel Gökçe et al.Experimental and therapeutic medicine, 15(6), 4697-4702 (2018-05-29) Neurochemical arguments for the use of dopamine DMei Huang et al.Pharmacology, biochemistry, and behavior, 157, 16-23 (2017-04-30) Coronary artery spasm as a cause of angina.Scott Kinlay Circulation, 129(17), 1717-1719 (2014-02-28) Effects of Riot Control Training on Systemic Microvascular Reactivity and Capillary Density.Flavio Pereira et al.Military medicine, 183(11-12), e713-e720 (2018-03-17) A novel α4/7-conotoxin LvIA from Conus lividus that selectively blocks α3β2 vs. α6/α3β2β3 nicotinic acetylcholine receptors.Sulan Luo et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(4), 1842-1853 (2014-01-09) Amplification of endothelium-dependent vasodilatation in contracting human skeletal muscle: role of KIR channels.Christopher M Hearon et al.The Journal of physiology, 597(5), 1321-1335 (2018-12-07) All muscarinic acetylcholine receptors (MBeatrice Mihaela Radu et al.Scientific reports, 7(1), 5083-5083 (2017-07-13) Mechanisms of vasorelaxation induced by total flavonoids of Euphorbia humifusa in rat aorta.T T Wang et al.Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 68(4), 619-628 (2017-11-21) Protein-mimicking nanowire-inspired electro-catalytic biosensor for probing acetylcholinesterase activity and its inhibitors.Qingqing Zhang et al.Talanta, 183, 258-267 (2018-03-24) Chronic treatment with paeonol improves endothelial function in mice through inhibition of endoplasmic reticulum stress-mediated oxidative stress.Ker Woon Choy et al.PloS one, 12(5), e0178365-e0178365 (2017-06-01) Characterization of procaine metabolism as probe for the butyrylcholinesterase enzyme investigation by simultaneous determination of procaine and its metabolite using capillary electrophoresis with electrochemiluminescence detection.Jipei Yuan et al.Journal of chromatography. A, 1154(1-2), 368-372 (2007-05-18) Brain endothelial TAK1 and NEMO safeguard the neurovascular unit.Dirk A Ridder et al.The Journal of experimental medicine, 212(10), 1529-1549 (2015-09-09) GluN2D-containing NMDA receptors inhibit neurotransmission in the mouse striatum through a cholinergic mechanism: implication for Parkinson's disease.Xiaoqun Zhang et al.Journal of neurochemistry, 129(4), 581-590 (2014-01-31) High Altitude Reduces NO-Dependent Myometrial Artery Vasodilator Response During Pregnancy.Ramón A Lorca et al.Hypertension (Dallas, Tex. : 1979), 73(6), 1319-1326 (2019-04-23) Microsomal Prostaglandin E Synthase-1 Plays a Critical Role in Long-term Motility Dysfunction after Bowel Obstruction.You-Min Lin et al.Scientific reports, 8(1), 8831-8831 (2018-06-13) Study of organic acids in Schisandrae Chinensis Fructus after vinegar processing.Fangzhou Yin et al.Journal of separation science, 40(20), 4012-4021 (2017-08-18) Dahl SS rats demonstrate enhanced aortic perivascular adipose tissue-mediated buffering of vasoconstriction through activation of NOS in the endothelium.Frank T Spradley et al.American journal of physiology. Regulatory, integrative and comparative physiology, 310(3), R286-R296 (2015-11-27) Protein-mimicking nanowire-inspired electro-catalytic biosensor for probing acetylcholinesterase activity and its inhibitors.Qingqing Zhang et al.Talanta, 183, 258-267 (2018-03-24) Chronic treatment with paeonol improves endothelial function in mice through inhibition of endoplasmic reticulum stress-mediated oxidative stress.Ker Woon Choy et al.PloS one, 12(5), e0178365-e0178365 (2017-06-01) Amplification of endothelium-dependent vasodilatation in contracting human skeletal muscle: role of KIR channels.Christopher M Hearon et al.The Journal of physiology, 597(5), 1321-1335 (2018-12-07) Microsomal Prostaglandin E Synthase-1 Plays a Critical Role in Long-term Motility Dysfunction after Bowel Obstruction.You-Min Lin et al.Scientific reports, 8(1), 8831-8831 (2018-06-13) Acetylcholine controls GABA-, glutamate-, and glycine-dependent giant depolarizing potentials that govern spontaneous motoneuron activity at the onset of synaptogenesis in the mouse embryonic spinal cord.Antonny Czarnecki et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(18), 6389-6404 (2014-05-03) Inhibitory effects of a standardized extract of Justicia pectoralis in an experimental rat model of airway hyper-responsiveness.Carlos T M Moura et al.The Journal of pharmacy and pharmacology, 69(6), 722-732 (2017-02-18) PPARδ agonist prevents endothelial dysfunction via induction of dihydrofolate reductase gene and activation of tetrahydrobiopterin salvage pathway.Zihui Zhang et al.British journal of pharmacology, 176(16), 2945-2961 (2019-05-31) Inhibition of bovine brain acetylcholinesterase by aluminum.M S Moraes et al.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 27(11), 2635-2638 (1994-11-01) Medial septum-diagonal band of Broca (MSDB) GABAergic regulation of hippocampal acetylcholine efflux is dependent on cognitive demands.Jessica J Roland et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(2), 506-514 (2014-01-10) Sepiapterin Improves Vascular Reactivity and Insulin-Stimulated Glucose in Wistar Rats.A C Keller et al.Oxidative medicine and cellular longevity, 2018, 7363485-7363485 (2018-10-23) Muscarinic receptor-mediated excitation of rat intracardiac ganglion neurons.Michiko Hirayama et al.Neuropharmacology, 95, 395-404 (2015-05-06) Reduced vascular responses to soluble guanylyl cyclase but increased sensitivity to sildenafil in female rats with type 2 diabetes.Styliani Goulopoulou et al.American journal of physiology. Heart and circulatory physiology, 309(2), H297-H304 (2015-05-10) Acetylcholine released from T cells regulates intracellular CaMasato Mashimo et al.Life sciences, 172, 13-18 (2016-12-28) Menthol Alone Upregulates Midbrain nAChRs, Alters nAChR Subtype Stoichiometry, Alters Dopamine Neuron Firing Frequency, and Prevents Nicotine Reward.Brandon J Henderson et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 36(10), 2957-2974 (2016-03-11) Decreased Kv1.5 expression in intrauterine growth retardation rats with exaggerated pulmonary hypertension.Ying Lv et al.American journal of physiology. Lung cellular and molecular physiology, 305(11), L856-L865 (2013-10-01) Allosteric Agonism of α7 Nicotinic Acetylcholine Receptors: Receptor Modulation Outside the Orthosteric Site.Alican Gulsevin et al.Molecular pharmacology, 95(6), 606-614 (2019-04-05) Apixaban Enhances Vasodilatation Mediated by Protease-Activated Receptor 2 in Isolated Rat Arteries.Ambra Villari et al.Frontiers in pharmacology, 8, 480-480 (2017-08-05) The interaction of the Chrna5 D398N variant with developmental nicotine exposure.H C O'Neill et al.Genes, brain, and behavior, 17(7), e12474-e12474 (2018-03-25) Accentuation of ursolic acid on muscarinic receptor-induced ANP secretion in beating rabbit atria.Hye Yoom Kim et al.Life sciences, 94(2), 145-150 (2013-12-18) Kinetics and molecular docking of dihydroxanthyletin-type coumarins from Angelica decursiva that inhibit cholinesterase and BACE1.Md Yousof Ali et al.Archives of pharmacal research, 41(7), 753-764 (2018-07-27) Prothrombin activator-like toxin appears to mediate cardiovascular collapse following envenoming by Pseudonaja textilis.Janeyuth Chaisakul et al.Toxicon : official journal of the International Society on Toxinology, 102, 48-54 (2015-05-12) Prefrontal cholinergic mechanisms instigating shifts from monitoring for cues to cue-guided performance: converging electrochemical and fMRI evidence from rats and humans.William M Howe et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(20), 8742-8752 (2013-05-17) Proteomics reveals potential non-neuronal cholinergic receptor-effectors in endothelial cells.Yuan-yuan Zhang et al.Acta pharmacologica Sinica, 35(9), 1137-1149 (2014-08-05) Arginase overexpression and NADPH oxidase stimulation underlie impaired vasodilation induced by advanced glycation end products.Hany M El-Bassossy et al.Biochemical and biophysical research communications, 499(4), 992-997 (2018-04-09) The prolactin family hormones regulate vascular tone through NO and prostacyclin production in isolated rat aortic rings.Carmen Gonzalez et al.Acta pharmacologica Sinica, 36(5), 572-586 (2015-04-22) [Diplopia following subcutaneous injections of botulinum toxin for cosmetic or medical use].Shira Sheen-Ophir et al.Harefuah, 152(2), 98-100 (2013-03-22) Walnut Protein Hydrolysates Play a Protective Role on Neurotoxicity Induced by d-Galactose and Aluminum Chloride in Mice.Li Feng et al.Molecules (Basel, Switzerland), 23(9) (2018-09-12) Ameliorating effect of Alpinia oxyphylla-Schisandra chinensis herb pair on cognitive impairment in a mouse model of Alzheimer's disease.Mengshi Wang et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 97, 128-135 (2017-10-29) COPD and asthma therapeutics for supportive treatment in organophosphate poisoning.Julia Herbert et al.Clinical toxicology (Philadelphia, Pa.), 57(7), 644-651 (2019-01-31) Antispasmodic, bronchodilator, vasorelaxant and cardiosuppressant effects of Buxus papillosa.Arif-Ullah Khan et al.BMC complementary and alternative medicine, 17(1), 54-54 (2017-01-20) Long-term effect of prazosin and losartan administration on blood pressure, heart, carotid artery, and acetylcholine induced dilation of cardiovascular system of young Wistar rats and SHR.Frantisek Kristek et al.General physiology and biophysics, 32(2), 235-243 (2013-05-18) Pharmacological characterization of the interaction between tiotropium bromide and olodaterol on human bronchi and small airways.Luigino Calzetta et al.Pulmonary pharmacology & therapeutics, 56, 39-50 (2019-03-17) Effect of the parasympathetic vasodilation on temperature regulation via trigeminal afferents in the orofacial area.Hanako Ohke et al.The journal of physiological sciences : JPS, 70(1), 22-22 (2020-04-03) Anti-inflammatory and autonomic effects of electroacupuncture in a rat model of diet-induced obesity.Xiaoyan Jie et al.Acupuncture in medicine : journal of the British Medical Acupuncture Society, 36(2), 103-109 (2018-03-01) Evidence for encoding versus retrieval scheduling in the hippocampus by theta phase and acetylcholine.Vincent Douchamps et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(20), 8689-8704 (2013-05-17) Nicotinic acetylcholine receptors in attention circuitry: the role of layer VI neurons of prefrontal cortex.Eliane Proulx et al.Cellular and molecular life sciences : CMLS, 71(7), 1225-1244 (2013-10-15) An integrated strategy for ascertaining quality marker of Schisandra chinensis (Turcz.) Baill based on correlation analysis between depression-related monoaminergic metabolites and chemical components profiling.Yiwen Zhang et al.Journal of chromatography. A, 1598, 122-131 (2019-05-03) Benidipine, an anti-hypertensive drug, relaxes mouse airway smooth muscle.Yongle Yang et al.Life sciences, 227, 74-81 (2019-04-20) Role of muscarinic receptors in the contraction of jejunal smooth muscle in the horse: An in vitro study.Alessandro Menozzi et al.Research in veterinary science, 115, 387-392 (2017-07-18) High Sodium Intake Impairs Small Artery Vasoreactivity in vivo in Dahl Salt-Sensitive Rats.Shi-Cheng Li et al.Journal of vascular research, 56(2), 65-76 (2019-05-13) Hydrogen sulfide improves endothelial dysfunction in hypertension by activating peroxisome proliferator-activated receptor delta/endothelial nitric oxide synthase signaling.Lin Xiao et al.Journal of hypertension, 36(3), 651-665 (2017-10-31) Anti-amnesic effect of extract and alkaloid fraction from aerial parts of Peganum harmala on scopolamine-induced memory deficits in mice.Wei Liu et al.Journal of ethnopharmacology, 204, 95-106 (2017-04-27) ADAMTS13 protects mice against renal ischemia-reperfusion injury by reducing inflammation and improving endothelial function.Suhan Zhou et al.American journal of physiology. Renal physiology, 316(1), F134-F145 (2018-11-22) t-Resveratrol Protects against Acute High Glucose Damage in Endothelial Cells.Leda Guzmán et al.Plant foods for human nutrition (Dordrecht, Netherlands), 73(3), 235-240 (2018-07-25) Characterization of the gastric motility response to human motilin and erythromycin in human motilin receptor-expressing transgenic mice.Shinichi Kato et al.PloS one, 14(2), e0205939-e0205939 (2019-02-23) Endothelium-dependent vasodilation effects ofYanyan Wang et al.Experimental and therapeutic medicine, 12(6), 3998-4006 (2017-01-20) Perilla frutescens Extract Ameliorates Acetylcholinesterase and Trimethyltin Chloride-Induced Neurotoxicity.Soo Jung Choi et al.Journal of medicinal food, 19(3), 281-289 (2015-10-28) Involvement of the ganglion cholinergic receptors in gonadotropin-releasing hormone, catecholamines, and progesterone release in the rat ovary.Cristina Daneri et al.Fertility and sterility, 99(7), 2062-2070 (2013-03-23) Impact of Immune Deficiency on Remodeling of Maternal Resistance Vasculature 4 Weeks Postpartum in Mice.Elizabeth A Bonney et al.Reproductive sciences (Thousand Oaks, Calif.), 24(4), 514-525 (2016-12-03) Luteolin Prevents Cardiometabolic Alterations and Vascular Dysfunction in Mice With HFD-Induced Obesity.Daniela Gentile et al.Frontiers in pharmacology, 9, 1094-1094 (2018-10-16) Uroprotective effect of ambroxol in cyclophosphamide-induced cystitis in mice.Elif Nur Barut et al.International urology and nephrology, 51(5), 803-810 (2019-03-22) Gulf War agent exposure causes impairment of long-term memory formation and neuropathological changes in a mouse model of Gulf War Illness.Zuchra Zakirova et al.PloS one, 10(3), e0119579-e0119579 (2015-03-19) Role of CSE-Produced H2S on Cerebrovascular Relaxation via RhoA-ROCK Inhibition and Cerebral Ischemia-Reperfusion Injury in Mice.Ji-Yue Wen et al.ACS chemical neuroscience, 10(3), 1565-1574 (2018-11-09) Chlorogenic acid improves ex vivo vessel function and protects endothelial cells against HOCl-induced oxidative damage, via increased production of nitric oxide and induction of Hmox-1.Rujia Jiang et al.The Journal of nutritional biochemistry, 27, 53-60 (2015-09-21) Vagal stimulation triggers peripheral vascular protection through the cholinergic anti-inflammatory pathway in a rat model of myocardial ischemia/reperfusion.Ming Zhao et al.Basic research in cardiology, 108(3), 345-345 (2013-03-23) Intra-nasal dopamine alleviates cognitive deficits in tgDISC1 rats which overexpress the human DISC1 gene.An-Li Wang et al.Neurobiology of learning and memory, 146, 12-20 (2017-11-07) Supplementation of cyanidin-3-O-β-glucoside promotes endothelial repair and prevents enhanced atherogenesis in diabetic apolipoprotein E-deficient mice.Yuhua Zhang et al.The Journal of nutrition, 143(8), 1248-1253 (2013-06-14) A Toll-Like Receptor 1/2 Agonist Augments Contractility in Rat Corpus Cavernosum.Inger Stallmann-Jorgensen et al.The journal of sexual medicine, 12(8), 1722-1731 (2015-08-04) Vampire Venom: Vasodilatory Mechanisms of Vampire Bat (Desmodus rotundus) Blood Feeding.Rahini Kakumanu et al.Toxins, 11(1) (2019-01-11) A free-choice high-fat, high-sucrose diet induces hyperphagia, obesity, and cardiovascular dysfunction in female cycling and pregnant rats.Hijab Ahmed et al.American journal of physiology. Regulatory, integrative and comparative physiology, 316(5), R472-R485 (2019-02-14) East asian variant of aldehyde dehydrogenase 2 is associated with coronary spastic angina: possible roles of reactive aldehydes and implications of alcohol flushing syndrome.Yuji Mizuno et al.Circulation, 131(19), 1665-1673 (2015-03-12) Vasorelaxant activities of Danhong injection and their differential effects on the rat abdominal aorta and mesenteric artery.Xianming Su et al.Journal of cardiovascular pharmacology, 65(1), 62-71 (2014-09-30) Endothelium-independent vasorelaxant effect of 20(S)-protopanaxadiol on isolated rat thoracic aorta.Lu Gan et al.Acta pharmacologica Sinica, 37(12), 1555-1562 (2016-09-13) Vasorelaxant and Hypotensive Effects of an Ethanolic Extract of Eulophia macrobulbon and Its Main Compound 1-(4'-Hydroxybenzyl)-4,8-Dimethoxyphenanthrene-2,7-Diol.Sutthinee Wisutthathum et al.Frontiers in pharmacology, 9, 484-484 (2018-06-07) Reactivity of rat bone marrow-derived macrophages to neurotransmitter stimulation in the context of collagen II-induced arthritis.Dominique Muschter et al.Arthritis research & therapy, 17, 169-169 (2015-06-25) LC-MS/MS-based quantification of tryptophan metabolites and neurotransmitters in the serum and brain of mice.Li-Sha Wang et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1112, 24-32 (2019-03-06) Improving vagal activity ameliorates cardiac fibrosis induced by angiotensin II: in vivo and in vitro.Jin-Jun Liu et al.Scientific reports, 5, 17108-17108 (2015-11-26) Poly (I:C) impairs NO donor-induced relaxation by overexposure to NO via the NF-kappa B/iNOS pathway in rat superior mesenteric arteries.Makoto Ando et al.Free radical biology & medicine, 112, 553-566 (2017-09-06) FRET Studies of Quinolone-Based Bitopic Ligands and Their Structural Analogues at the Muscarinic MRegina Messerer et al.ACS chemical biology, 12(3), 833-843 (2017-01-25) Biochemical, Anatomical, and Pharmacological Characterization of Calcitonin-Type Neuropeptides in Starfish: Discovery of an Ancient Role as Muscle Relaxants.Weigang Cai et al.Frontiers in neuroscience, 12, 382-382 (2018-06-26) Renal protective effects of induction of haem oxygenase-1 combined with increased adiponectin on the glomerular vascular endothelial growth factor-nitric oxide axis in obese rats.Xue Liu et al.Experimental physiology, 100(7), 865-876 (2015-05-12) Selective potentiation of (α4)3(β2)2 nicotinic acetylcholine receptors augments amplitudes of prefrontal acetylcholine- and nicotine-evoked glutamatergic transients in rats.Morten Grupe et al.Biochemical pharmacology, 86(10), 1487-1496 (2013-09-21) Effects of phenolic constituents of daylily flowers on corticosterone- and glutamate-treated PC12 cells.Huan Tian et al.BMC complementary and alternative medicine, 17(1), 69-69 (2017-01-23) Effect of hyperpolarization-activated current I(f) on robustness of sinoatrial node pacemaking: theoretical study on influence of intracellular Na(+) concentration.Yasutaka Kurata et al.American journal of physiology. Heart and circulatory physiology, 304(10), H1337-H1351 (2013-03-19) Probing structural requirements of positive allosteric modulators of the M4 muscarinic receptor.Tracey Huynh et al.Journal of medicinal chemistry, 56(20), 8196-8200 (2013-10-01) The evaluation of penile microvascular endothelial function using laser speckle contrast imaging in healthy volunteers.Valéria Verri et al.Microvascular research, 99, 96-101 (2015-04-07) Chemerin reduces vascular nitric oxide/cGMP signalling in rat aorta: a link to vascular dysfunction in obesity?Neves KB, Lobato NS, Lopes RA, et al. Clinical Science, 127(2), 111-122 (2014) Kinetic characterization of a cocaine hydrolase engineered from mouse butyrylcholinesterase.Xiabin Chen et al.The Biochemical journal, 466(2), 243-251 (2014-12-09) Choline ameliorates cardiac hypertrophy by regulating metabolic remodelling and UPRmt through SIRT3-AMPK pathway.Man Xu et al.Cardiovascular research, 115(3), 530-545 (2018-08-31) In vitro and in vivo metabolism and inhibitory activities of vasicine, a potent acetylcholinesterase and butyrylcholinesterase inhibitor.Wei Liu et al.PloS one, 10(4), e0122366-e0122366 (2015-04-08) Where attention falls: Increased risk of falls from the converging impact of cortical cholinergic and midbrain dopamine loss on striatal function.Martin Sarter et al.Experimental neurology, 257, 120-129 (2014-05-09) (S)-5-ethynyl-anabasine, a novel compound, is a more potent agonist than other nicotine alkaloids on the nematode Asu-ACR-16 receptor.Fudan Zheng et al.International journal for parasitology. Drugs and drug resistance, 7(1), 12-22 (2016-12-30) Knockout of Ceramide Kinase Aggravates Pathological and Lethal Responses in Mice with Experimental Colitis.Satomi Suzuki et al.Biological & pharmaceutical bulletin, 41(5), 797-805 (2018-05-02) α7 nicotinic ACh receptor-deficient mice exhibit sustained attention impairments that are reversed by β2 nicotinic ACh receptor activation.Benjamin Kolisnyk et al.British journal of pharmacology, 172(20), 4919-4931 (2015-07-30) Elimination of vitamin D receptor in vascular endothelial cells alters vascular function.Ni W, Watts SW, Ng M, et al. Hypertension, 64(6), 1290-1298 (2014) Forget-me-some: General versus special purpose models in a hierarchical probabilistic task.Franziska Bröker et al.PloS one, 13(10), e0205974-e0205974 (2018-10-23) Y-chromosome lineage determines cardiovascular organ T-cell infiltration in the stroke-prone spontaneously hypertensive rat.Shanzana I Khan et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 32(5), 2747-2756 (2018-01-06) Treatment with salvianolic acid B restores endothelial function in angiotensin II-induced hypertensive mice.Wei Chih Ling et al.Biochemical pharmacology, 136, 76-85 (2017-04-12) Cigarette smoke and non-neuronal cholinergic system in the airway epithelium of COPD patients.Angela M Montalbano et al.Journal of cellular physiology, 233(8), 5856-5868 (2017-12-12) Protective effects of exercise training on endothelial dysfunction induced by total sleep deprivation in healthy subjects.Fabien Sauvet et al.International journal of cardiology, 232, 76-85 (2017-01-17) [The role of spinal motoneurons in the mechanisms of hypogravitational motor syndrome development].R R Islamov et al.Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 99(3), 281-293 (2013-06-26) Mild caloric restriction reduces blood pressure and activates endothelial AMPK-PI3K-Akt-eNOS pathway in obese Zucker rats.C F García-Prieto et al.Vascular pharmacology, 65-66, 3-12 (2014-12-23) Linalyl acetate prevents olmesartan-induced intestinal hypermotility mediated by interference of the sympathetic inhibitory pathway in hypertensive rat.Soonho Kwon et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 102, 362-368 (2018-03-24) P2Y₂ and Gq/G₁₁ control blood pressure by mediating endothelial mechanotransduction.ShengPeng Wang et al.The Journal of clinical investigation, 125(8), 3077-3086 (2015-07-15) The effects of Secondhand Smoke (SHS) exposure on microvascular endothelial function among healthy women.Zulkefli Sanip et al.Tobacco induced diseases, 13(1), 32-32 (2015-09-09) Tissue-specific effects of acetylcholine in the canine heart.Kirstine Calloe et al.American journal of physiology. Heart and circulatory physiology, 305(1), H66-H75 (2013-05-07) Elastase alters contractility and promotes an inflammatory synthetic phenotype in airway smooth muscle tissues.Angelia D Lockett et al.American journal of physiology. Lung cellular and molecular physiology, 314(4), L626-L634 (2017-12-08) GFPT1-myasthenia: clinical, structural, and electrophysiologic heterogeneity.Duygu Selcen et al.Neurology, 81(4), 370-378 (2013-06-25) Intradermal administration of ATP augments methacholine-induced cutaneous vasodilation but not sweating in young males and females.Naoto Fujii et al.American journal of physiology. Regulatory, integrative and comparative physiology, 309(8), R912-R919 (2015-08-21) Eugenol and carvone as relaxants of arsenic and mercury hypercontracted rat trachea.Swati Kundu et al.Toxicology and industrial health, 32(12), 1935-1941 (2015-09-19) Effects of recombinant human erythropoietin on resistance artery endothelial function in stage 4 chronic kidney disease.Marie Briet et al.Journal of the American Heart Association, 2(2), e000128-e000128 (2013-04-16) N-Cadherin, a novel and rapidly remodelling site involved in vasoregulation of small cerebral arteries.Zhe Sun et al.The Journal of physiology, 595(6), 1987-2000 (2016-12-23) Heart-specific overexpression of choline acetyltransferase gene protects murine heart against ischemia through hypoxia-inducible factor-1α-related defense mechanisms.Yoshihiko Kakinuma et al.Journal of the American Heart Association, 2(1), e004887-e004887 (2013-03-26) Effects of Institut Georges Lopez-1 and Celsior preservation solutions on liver graft injury.Donia Tabka et al.World journal of gastroenterology, 21(14), 4159-4168 (2015-04-22) Exendin-4 attenuates brain mitochondrial toxicity through PI3K/Akt-dependent pathway in amyloid beta (1-42)-induced cognitive deficit rats.Debapriya Garabadu et al.Neurochemistry international, 128, 39-49 (2019-04-21) Stereoselective glucuronidation metabolism, pharmacokinetics, anti-amnesic pharmacodynamics, and toxic properties of vasicine enantiomers in vitro and in vivo.Yudan Zhu et al.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 123, 459-474 (2018-08-06) Folic acid supplementation increases cutaneous vasodilator sensitivity to sympathetic nerve activity in older adults.Anna E Stanhewicz et al.American journal of physiology. Regulatory, integrative and comparative physiology, 312(5), R681-R688 (2017-02-24) In vivo and in vitro attenuation of naloxone-precipitated experimental opioid withdrawal syndrome by insulin and selective KATP channel modulator.Prabhat Singh et al.Psychopharmacology, 232(2), 465-475 (2014-07-26) Hippocampal-dependent memory deficit induced by perinatal exposure to polutted eels in middle-aged offspring mice: Sex differential effects.Nidhal Soualeh et al.Toxicology letters, 280, 247-258 (2017-08-30) Chronic kidney disease after 5/6 nephrectomy disturbs the intestinal microbiota and alters intestinal motility.Kazuhiro Nishiyama et al.Journal of cellular physiology, 234(5), 6667-6678 (2018-10-15) ATP release from freshly isolated guinea-pig bladder urothelial cells: a quantification and study of the mechanisms involved.Linda M McLatchie et al.BJU international, 115(6), 987-993 (2014-10-14) Grid-layout and theta-modulation of layer 2 pyramidal neurons in medial entorhinal cortex.Saikat Ray et al.Science (New York, N.Y.), 343(6173), 891-896 (2014-01-25) Initial studies on the direct and modulatory effects of nitric oxide on an identified central Helix aspersa neuron.Nicholas J D Wright et al.Invertebrate neuroscience : IN, 15(1), 175-175 (2014-11-09) Reduction of angiotensin A and alamandine vasoactivity in the rabbit model of atherogenesis: differential effects of alamandine and Ang(1-7).Belthrand Habiyakare et al.International journal of experimental pathology, 95(4), 290-295 (2014-06-24) Beneficial Effect of Berberis amurensis Rupr. on Penile Erection.Rui Tan et al.Chinese journal of integrative medicine, 24(6), 448-454 (2018-01-18) Synaptotagmin-2, and -1, linked to neurotransmission impairment and vulnerability in Spinal Muscular Atrophy.Rocío Tejero et al.Human molecular genetics, 25(21), 4703-4716 (2017-02-09) Experimental evidence and mathematical modeling of thermal effects on human colonic smooth muscle contractility.A Altomare et al.American journal of physiology. Gastrointestinal and liver physiology, 307(1), G77-G88 (2014-05-17) Dynamics of hippocampal acetylcholine release during lithium-pilocarpine-induced status epilepticus in rats.Markus H Hillert et al.Journal of neurochemistry, 131(1), 42-52 (2014-06-10) Increased circulating trimethylamine N-oxide plays a contributory role in the development of endothelial dysfunction and hypertension in the RUPP rat model of preeclampsia.Hui Chen et al.Hypertension in pregnancy, 38(2), 96-104 (2019-03-02) Selective ER-α agonist alleviates vascular endothelial dysfunction in ovariectomized type 2 diabetic rats.Seema Bansal et al.Molecular and cellular endocrinology, 460, 152-161 (2017-07-25) Indoxyl sulfate potentiates endothelial dysfunction via reciprocal role for reactive oxygen species and RhoA/ROCK signaling in 5/6 nephrectomized rats.Shuang Chu et al.Free radical research, 51(3), 237-252 (2017-03-10) Acetylcholinesterase affinity-based screening assay on Lippia gracilis Schauer extracts.K L Vanzolini et al.Journal of pharmaceutical and biomedical analysis, 153, 232-237 (2018-03-06) Receptor Species-dependent Desensitization Controls KCNQ1/KCNE1 K+ Channels as Downstream Effectors of Gq Protein-coupled Receptors.Marie-Cécile Kienitz et al.The Journal of biological chemistry, 291(51), 26410-26426 (2016-11-12) Acute and chronic effects of botulinum neurotoxin a on the mammalian neuromuscular junction.Padmamalini Baskaran et al.Muscle & nerve, 50(2), 206-215 (2013-11-13) Underlying mechanisms preserving coronary basal tone and NO-mediated relaxation in obesity: Involvement of β1 subunit-mediated upregulation of BKBelén Climent et al.Atherosclerosis, 263, 227-236 (2017-07-04) Involvement of cholinergic and adenosinergic systems on the branchial immune response of experimentally infected silver catfish with Streptococcus agalactiae.M D Baldissera et al.Journal of fish diseases, 41(1), 27-32 (2017-07-13) Layer-specific interference with cholinergic signaling in the prefrontal cortex by smoking concentrations of nicotine.Rogier B Poorthuis et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(11), 4843-4853 (2013-03-15) Decreased vasodilatory effect of Tanshinone ⅡA Sodium Sulfonate on mesenteric artery in hypertension.Yuanqun Zhou et al.European journal of pharmacology, 854, 365-371 (2019-05-06) Influence of Luehea divaricata Mart. extracts on peripheral vascular resistance and the role of nitric oxide and both Ca+2-sensitive and Kir6.1 ATP-sensitive K+ channels in the vasodilatory effects of isovitexin on isolated perfused mesenteric beds.Cleide Adriane Signor Tirloni et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 56, 74-82 (2019-01-23) Tetrahydroxystilbene Glycoside Improves Microvascular Endothelial Dysfunction and Ameliorates Obesity-Associated Hypertension in Obese ZDF Rats Via Inhibition of Endothelial Autophagy.Qianqian Dong et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 43(1), 293-307 (2017-08-31) CD14Karol Urbanski et al.Thrombosis and haemostasis, 117(5), 971-980 (2017-02-24) ACh-induced hyperpolarization and decreased resistance in mammalian type II vestibular hair cells.Lauren A Poppi et al.Journal of neurophysiology, 119(1), 312-325 (2017-10-06) The enhancement of TXASu-Juan Kuang et al.European journal of pharmacology, 805, 93-100 (2017-03-14) Presynaptic and postsynaptic regulation of muscle contractions in the ascarid nematode Ascaris suum: a target for drug action.S M Trailović et al.Journal of helminthology, 90(6), 698-705 (2015-11-28) Vasoactive effects of prostaglandins from the perivascular fat of mesenteric resistance arteries in WKY and SHROB rats.Yolanda Mendizábal et al.Life sciences, 93(25-26), 1023-1032 (2013-11-10) Acetylcholine suppresses microglial inflammatory response via α7nAChR to protect hippocampal neurons.Lin Li et al.Journal of integrative neuroscience, 18(1), 51-56 (2019-05-17) RAGE mediates the inactivation of nAChRs in sympathetic neurons under high glucose conditions.Andrew R Chandna et al.The European journal of neuroscience, 41(3), 341-351 (2014-11-29) Determination of amines and phenolic acids in wine with benzoyl chloride derivatization and liquid chromatography-mass spectrometry.Paige A Malec et al.Journal of chromatography. A, 1523, 248-256 (2017-08-05) LC-MS/MS imaging with thermal film-based laser microdissection.Michiko Oya et al.Analytical and bioanalytical chemistry, 410(2), 491-499 (2017-12-01) Zebrafish as a Model for Epilepsy-Induced Cognitive Dysfunction: A Pharmacological, Biochemical and Behavioral Approach.Uday P Kundap et al.Frontiers in pharmacology, 8, 515-515 (2017-08-22) Yu-Min Xu et al.Neural regeneration research, 14(5), 794-804 (2019-01-29)Kai Xin San (KXS, containing ginseng, hoelen, polygala, and acorus), a traditional Chinese herbal compound, has been found to regulate cognitive dysfunction; however, its mechanism of action is still unclear. In this study, 72 specific-pathogen-free male Kunming mice aged 8... Vascular injury in diabetic db/db mice is ameliorated by atorvastatin: role of Rac1/2-sensitive Nox-dependent pathways.Thiago Bruder-Nascimento et al.Clinical science (London, England : 1979), 128(7), 411-423 (2014-11-02) Irisin improves endothelial function in obese mice through the AMPK-eNOS pathway.Fang Han et al.American journal of physiology. Heart and circulatory physiology, 309(9), H1501-H1508 (2015-09-16) Inhibition of the high affinity choline transporter enhances hyperalgesia in a rat model of chronic pancreatitis.Dan Luo et al.Biochemical and biophysical research communications, 488(1), 204-210 (2017-05-10) Elevated extracellular potassium prior to muscle contraction reduces onset and steady-state exercise hyperemia in humans.Janée D Terwoord et al.Journal of applied physiology (Bethesda, Md. : 1985), 125(2), 615-623 (2018-05-04) A Genetically Encoded Fluorescent Sensor for Rapid and Specific In Vivo Detection of Norepinephrine.Jiesi Feng et al.Neuron, 102(4), 745-761 (2019-03-30) Visceral adipose tissue-derived serine protease inhibitor augments acetylcholine-induced relaxation via the inhibition of acetylcholine esterase activity in rat isolated mesenteric artery.S Kameshima et al.Acta physiologica (Oxford, England), 216(2), 203-210 (2015-08-13) Neuronal nitric oxide synthase-derived hydrogen peroxide effect in grafts used in human coronary bypass surgery.Patrick Wander Endlich et al.Clinical science (London, England : 1979), 131(10), 1015-1026 (2017-04-01) S-equol Partially Restored Endothelial Nitric Oxide Production in Isoflavone-deficient Ovariectomized Rats.Yoshinori Ohkura et al.Journal of cardiovascular pharmacology, 65(5), 500-507 (2015-01-31) Tetrahydrocurcumin protects against cadmium-induced hypertension, raised arterial stiffness and vascular remodeling in mice.Weerapon Sangartit et al.PloS one, 9(12), e114908-e114908 (2014-12-17) Ellagic Acid Reduces High Glucose-Induced Vascular Oxidative Stress Through ERK1/2/NOX4 Signaling Pathway.Artur Rozentsvit et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 44(3), 1174-1187 (2017-11-28) Burn Injury Alters Epidermal Cholinergic Mediators and Increases HMGB1 and Caspase 3 in Autologous Donor Skin and Burn Margin.Casey J Holmes et al.Shock (Augusta, Ga.), 47(2), 175-183 (2016-09-21) Frequency-dependent, cell type-divergent signaling in the hippocamposeptal projection.Joanna Mattis et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(35), 11769-11780 (2014-08-29) Dietary polyphenol morin rescues endothelial dysfunction in a diabetic mouse model by activating the Akt/eNOS pathway.Kumiko Taguchi et al.Molecular nutrition & food research, 60(3), 580-588 (2015-12-03) IL-17A modulates oxidant stress-induced airway hyperresponsiveness but not emphysema.Mariona Pinart et al.PloS one, 8(3), e58452-e58452 (2013-03-19) Silver nanoparticles induce anti-proliferative effects on airway smooth muscle cells. Role of nitric oxide and muscarinic receptor signaling pathway.Manuel A Ramírez-Lee et al.Toxicology letters, 224(2), 246-256 (2013-11-06) Impaired Pulmonary Arterial Vasoconstriction and Nitric Oxide-Mediated Relaxation Underlie Severe Pulmonary Hypertension in the Sugen-Hypoxia Rat Model.Helen Christou et al.The Journal of pharmacology and experimental therapeutics, 364(2), 258-274 (2017-12-08) Piracetam Facilitates the Anti-Amnesic but not Anti-Diabetic Activity of Metformin in Experimentally Induced Type-2 Diabetic Encephalopathic Rats.Shruti Pandey et al.Cellular and molecular neurobiology, 37(5), 791-802 (2016-09-03) Juvenile growth reduces the influence of epithelial sodium channels on myogenic tone in skeletal muscle arterioles.Lori S Kang et al.Clinical and experimental pharmacology & physiology, 43(12), 1199-1207 (2016-08-26) Antidiabetic effect of Euterpe oleracea Mart. (açaí) extract and exercise training on high-fat diet and streptozotocin-induced diabetic rats: A positive interaction.Graziele Freitas de Bem et al.PloS one, 13(6), e0199207-e0199207 (2018-06-20) Positive feedback regulation of agonist-stimulated endothelial Ca2+ dynamics by KCa3.1 channels in mouse mesenteric arteries.Xun Qian et al.Arteriosclerosis, thrombosis, and vascular biology, 34(1), 127-135 (2013-11-02) Effect of inhaled MgSO4 on FEV1 and PEF in children with asthma induced by acetylcholine: a randomized controlled clinical trail of 330 cases.Y X Sun et al.Journal of tropical pediatrics, 60(2), 141-147 (2013-12-18) The functional and structural changes in the basilar artery due to overpressure blast injury.Hale Z Toklu et al.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 35(12), 1950-1956 (2015-06-25) Comparison of the porcine uterine smooth muscle contractility on days 12-14 of the estrous cycle and pregnancy.Włodzimierz Markiewicz et al.Acta veterinaria Scandinavica, 58, 20-20 (2016-03-24) Hypercaloric Diet Establishes Erectile Dysfunction in Rat: Mechanisms Underlying the Endothelial Damage.Iara L L de Souza et al.Frontiers in physiology, 8, 760-760 (2017-11-01) Readthrough acetylcholinesterase (AChE-R) and regulated necrosis: pharmacological targets for the regulation of ovarian functions?J Blohberger et al.Cell death & disease, 6, e1685-e1685 (2015-03-15) Isolation of canine coronary sinus musculature from the atria by radiofrequency catheter ablation prevents induction of atrial fibrillation.Hiroshi Morita et al.Circulation. Arrhythmia and electrophysiology, 7(6), 1181-1188 (2014-11-09) Quantitative-profiling of neurotransmitter abnormalities in the disease progression of experimental diabetic encephalopathy rat.Xueyan Zhou et al.Canadian journal of physiology and pharmacology, 93(11), 1007-1013 (2015-10-02) Metabolic Syndrome Induced Bladder Cannabinoid Receptor Changes in the Fructose-Fed Rats.I-Hung Chen et al.Lower urinary tract symptoms, 10(2), 198-203 (2017-04-08) Xyloketal B exerts antihypertensive effect in renovascular hypertensive rats via the NO-sGC-cGMP pathway and calcium signaling.Li-Yan Zhao et al.Acta pharmacologica Sinica, 39(5), 875-884 (2018-03-30) The effects of substance P and acetylcholine on human tenocyte proliferation converge mechanistically via TGF-β1.Gloria Fong et al.PloS one, 12(3), e0174101-e0174101 (2017-03-17) Antioxidant hydrolyzed peptides from Manchurian walnut (Juglans mandshurica Maxim.) attenuate scopolamine-induced memory impairment in mice.Dayong Ren et al.Journal of the science of food and agriculture, 98(13), 5142-5152 (2018-04-14) The PI3K-Akt-eNOS pathway is involved in aortic hyporeactivity to Phenylephrine associated with late pregnancy in spontaneously hypertensive rats.Dalise Zancheta et al.Life sciences, 122, 78-86 (2014-12-24) Menin: a tumor suppressor that mediates postsynaptic receptor expression and synaptogenesis between central neurons of Lymnaea stagnalis.Nichole Flynn et al.PloS one, 9(10), e111103-e111103 (2014-10-28) Juan Zhou et al.Frontiers in pharmacology, 9, 389-389 (2018-05-10)The extract of Moringa oleifera seeds has been shown to possess various pharmacological properties. In the present study, we assessed the neuropharmacological effects of 70% ethanolic M. oleifera seed extract (MSE) on cognitive impairment caused by scopolamine injection in mice... Functional estimation of endothelin-1 receptor antagonism by bosentan, macitentan and ambrisentan in human pulmonary and radial arteries in vitro.James A Angus et al.European journal of pharmacology, 804, 111-116 (2017-03-17) Influence of gαq on the dynamics of m3-acetylcholine receptor-g-protein-coupled receptor kinase 2 interaction.Valerie Wolters et al.Molecular pharmacology, 87(1), 9-17 (2014-10-16) DoesMojtaba Mohseni et al.Veterinary research forum : an international quarterly journal, 8(2), 115-120 (2017-08-09) Rhynchophylline Ameliorates Endothelial Dysfunction via Src-PI3K/Akt-eNOS Cascade in the Cultured Intrarenal Arteries of Spontaneous Hypertensive Rats.Hui-Feng Hao et al.Frontiers in physiology, 8, 928-928 (2017-12-01) Angiotensin-Converting Enzyme 2 in the Rostral Ventrolateral Medulla Regulates Cholinergic Signaling and Cardiovascular and Sympathetic Responses in Hypertensive Rats.Yu Deng et al.Neuroscience bulletin, 35(1), 67-78 (2018-10-16) Metabotropic and ionotropic glutamate receptors mediate the modulation of acetylcholine release at the frog neuromuscular junction.Andrei Tsentsevitsky et al.Journal of neuroscience research, 95(7), 1391-1401 (2016-10-23) Block of nicotinic acetylcholine receptors by philanthotoxins is strongly dependent on their subunit composition.Hamid S Kachel et al.Scientific reports, 6, 38116-38116 (2016-12-03) Vanadium exposure-induced striatal learning and memory alterations in rats.Liping Sun et al.Neurotoxicology, 62, 124-129 (2017-06-20) Cholinergic Neurons in the Basal Forebrain Promote Wakefulness by Actions on Neighboring Non-Cholinergic Neurons: An Opto-Dialysis Study.Janneke C Zant et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 36(6), 2057-2067 (2016-02-13) Black tea protects against hypertension-associated endothelial dysfunction through alleviation of endoplasmic reticulum stress.Wai San Cheang et al.Scientific reports, 5, 10340-10340 (2015-05-16) Alterations in endothelin type B receptor contribute to microvascular dysfunction in women who have had preeclampsia.Anna E Stanhewicz et al.Clinical science (London, England : 1979), 131(23), 2777-2789 (2017-10-19) Metformin ameliorates ovariectomy-induced vascular dysfunction in non-diabetic Wistar rats.Oliveira PW, de Sousa GJ, Caliman IF, et al. Clinical Science, 127(4), 265-275 (2014) Benzofuran-chalcone hybrids as potential multifunctional agents against Alzheimer's disease: synthesis and in vivo studies with transgenic Caenorhabditis elegans.Koneni V Sashidhara et al.ChemMedChem, 9(12), 2671-2684 (2014-09-25) Cholinergic agonists increase intracellular calcium concentration in guinea pig vestibular hair cells.W Han et al.Chinese medical journal, 114(7), 714-717 (2002-01-10) Echocardiographic Epicardial Adipose Tissue Thickness Is Associated with Symptomatic Coronary Vasospasm during Provocative Testing.Susumu Nishio et al.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 30(10), 1021-1027 (2017-08-28) Hyperactivation of B-type motor neurons results in aberrant synchrony of the Caenorhabditis elegans motor circuit.Yingchuan B Qi et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(12), 5319-5325 (2013-03-22) Phosphatidylinositol4-phosphate 5-kinase prevents the decrease in the HERG potassium current induced by Gq protein-coupled receptor stimulation.Taeko Kubo et al.Journal of pharmacological sciences, 127(1), 127-134 (2015-02-24) Acetylcholine attenuated TNF-α-induced intracellular CaMing Zhao et al.Journal of molecular and cellular cardiology, 107, 1-12 (2017-04-12) Galanin decreases spontaneous resting contractions and potentiates acetyl choline-induced contractions of goldfish gut.Elsie Tachie Mensah et al.Neuropeptides, 69, 92-97 (2018-05-02) Role of cyclooxygenase in the vascular response to locally delivered acetylcholine in Caucasian and African descent individuals.Matthew J Maley et al.Microvascular research, 111, 80-87 (2017-01-22) Dissociable dopamine dynamics for learning and motivation.Ali Mohebi et al.Nature, 570(7759), 65-70 (2019-05-24) The voltage-sensitive cardiac M2 muscarinic receptor modulates the inward rectification of the G protein-coupled, ACh-gated K+ current.Pedro D Salazar-Fajardo et al.Pflugers Archiv : European journal of physiology, 470(12), 1765-1776 (2018-08-30) ACR-12 ionotropic acetylcholine receptor complexes regulate inhibitory motor neuron activity in Caenorhabditis elegans.Hilary A Petrash et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(13), 5524-5532 (2013-03-29) The cordycepin derivative IMM-H007 improves endothelial dysfunction by suppressing vascular inflammation and promoting AMPK-dependent eNOS activation in high-fat diet-fed ApoE knockout mice.Min-Jie Wang et al.European journal of pharmacology, 852, 167-178 (2019-03-04) Epigallocatechin gallate attenuates ET-1-induced contraction in carotid artery from type 2 diabetic OLETF rat at chronic stage of disease.Takayuki Matsumoto et al.Life sciences, 118(2), 200-205 (2013-12-03) TRPV1 enhances the afferent response to P2X receptor activation in the mouse urinary bladder.Luke Grundy et al.Scientific reports, 8(1), 197-197 (2018-01-11) Berberine improves endothelial function by inhibiting endoplasmic reticulum stress in the carotid arteries of spontaneously hypertensive rats.Limei Liu et al.Biochemical and biophysical research communications, 458(4), 796-801 (2015-02-18) Role of endogenous vascular endothelial growth factor in endothelium-dependent vasodilation in humans.Anna M J Thijs et al.Hypertension (Dallas, Tex. : 1979), 61(5), 1060-1065 (2013-03-20) Flagellin/TLR5 signaling potentiates airway serous secretion from swine tracheal submucosal glands.Soshi Muramatsu et al.American journal of physiology. Lung cellular and molecular physiology, 305(11), L819-L830 (2013-10-08) Chronic administration of sildenafil improves endothelial function in spontaneously hypertensive rats by decreasing COX-2 expression and oxidative stress.José Jairo Teixeira-da-Silva et al.Life sciences, 225, 29-38 (2019-04-04) Vascular responses of the extremities to transdermal application of vasoactive agents in Caucasian and African descent individuals.Matthew J Maley et al.European journal of applied physiology, 115(8), 1801-1811 (2015-04-05) Central administration of TRV027 improves baroreflex sensitivity and vascular reactivity in spontaneously hypertensive rats.Alynne Carvalho-Galvão et al.Clinical science (London, England : 1979), 132(14), 1513-1527 (2018-06-16) Novel mechanism of hydrogen sulfide-induced guinea pig urinary bladder smooth muscle contraction: role of BK channels and cholinergic neurotransmission.Vítor S Fernandes et al.American journal of physiology. Cell physiology, 309(2), C107-C116 (2015-05-08) VPAC1 receptors regulate intestinal secretion and muscle contractility by activating cholinergic neurons in guinea pig jejunum.Candice Fung et al.American journal of physiology. Gastrointestinal and liver physiology, 306(9), G748-G758 (2014-03-01) The usefulness of short-term high-fat/high salt diet as a model of metabolic syndrome in mice.Leônidas Graças Mendes-Junior et al.Life sciences, 209, 341-348 (2018-08-18) Effect of short-term androgen deficiency on bladder contractility and urothelial mediator release.Giselle Bravo et al.Naunyn-Schmiedeberg's archives of pharmacology, 390(5), 547-556 (2017-02-13) The Inhibitory Mechanism on Acetylcholine-Induced Contraction of Bladder Smooth Muscle in the Streptozotocin-Induced Diabetic Rat.Jong Soo Han et al.Biomolecules & therapeutics, 27(1), 101-106 (2018-11-14) The Coordinated Activities of nAChR and Wnt Signaling Regulate Intestinal Stem Cell Function in Mice.Toshio Takahashi et al.International journal of molecular sciences, 19(3) (2018-03-08) Differences in control of parasympathetic vasodilation between submandibular and sublingual glands in the rat.Toshiya Sato et al.American journal of physiology. Regulatory, integrative and comparative physiology, 309(11), R1432-R1438 (2015-09-12) Interaction between substrates suggests a relationship between organophosphorus-sensitive phenylvalerate- and acetylcholine-hydrolyzing activities in chicken brain.Mónica Benabent et al.Toxicology letters, 230(2), 132-138 (2014-03-01) The effect of insulin to decrease neointimal growth after arterial injury is endothelial nitric oxide synthase-dependent.June Guo et al.Atherosclerosis, 241(1), 111-120 (2015-05-15) Acetylcholine encodes long-lasting presynaptic plasticity at glutamatergic synapses in the dorsal striatum after repeated amphetamine exposure.Wengang Wang et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(25), 10405-10426 (2013-06-21) Translational Study Searching for Synergy between Glycopyrronium and Indacaterol.Mario Cazzola et al.COPD, 12(2), 175-181 (2014-09-16) Adipocytokine, progranulin, augments acetylcholine-induced nitric oxide-mediated relaxation through the increases of cGMP production in rat isolated mesenteric artery.K Kazama et al.Acta physiologica (Oxford, England), 219(4), 781-789 (2016-06-23) pH-Responsive Fluorescence Enhancement in Graphene Oxide-Naphthalimide Nanoconjugates: A Fluorescence Turn-On Sensor for Acetylcholine.Sreejith Mangalath et al.Chemistry (Weinheim an der Bergstrasse, Germany), 23(47), 11404-11409 (2017-06-18) Human polymorphisms in nicotinic receptors: a functional analysis in iPS-derived dopaminergic neurons.Cristina Deflorio et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 31(2), 828-839 (2016-11-20) Stoichiometry for activation of neuronal α7 nicotinic receptors.Natalia Andersen et al.Proceedings of the National Academy of Sciences of the United States of America, 110(51), 20819-20824 (2013-12-04) Is internal thoracic artery resistant to reperfusion injury? Evaluation of the storage of free internal thoracic artery grafts.Gábor Veres et al.The Journal of thoracic and cardiovascular surgery, 156(4), 1460-1469 (2018-09-28) Mineralocorticoid receptor antagonism reverses diabetes-related coronary vasodilator dysfunction: A unique vascular transcriptomic signature.Scott M Brown et al.Pharmacological research, 134, 100-108 (2018-06-06) Rahini Kakumanu et al.Toxins, 11(4) (2019-04-04)Russell's viper (Daboia russelii) venom causes a range of clinical effects in humans. Hypotension is an uncommon but severe complication of Russell's viper envenoming. The mechanism(s) responsible for this effect are unclear. In this study, we examined the cardiovascular effects... Curcumin analogues inhibit phosphodiesterase-5 and dilate rat pulmonary arteries.Oraya Kruangtip et al.The Journal of pharmacy and pharmacology, 67(1), 87-95 (2014-09-02) Different Bioactive Neuropeptides are Expressed in Two Sub-Classes of GABAergic RME Nerve Ring Motorneurons in Ascaris suum.Jennifer J Knickelbine et al.ACS chemical neuroscience, 9(8), 2025-2040 (2018-02-06) Molecular function of the novel α7β2 nicotinic receptor.Beatriz E Nielsen et al.Cellular and molecular life sciences : CMLS, 75(13), 2457-2471 (2018-01-10) Inhibition of bone morphogenic protein 4 restores endothelial function in db/db diabetic mice.Yang Zhang et al.Arteriosclerosis, thrombosis, and vascular biology, 34(1), 152-159 (2013-11-10) Titania coating of mesoporous silica nanoparticles for improved biocompatibility and drug release within blood vessels.Asima Farooq et al.Acta biomaterialia, 76, 208-216 (2018-06-23) Clinical usefulness, angiographic characteristics, and safety evaluation of intracoronary acetylcholine provocation testing among 921 consecutive white patients with unobstructed coronary arteries.Peter Ong et al.Circulation, 129(17), 1723-1730 (2014-02-28) Tail vein injection of mmLDL upregulates mouse mesenteric artery ETYang Liu et al.Vascular pharmacology, 96-98, 33-39 (2017-08-12) Quantification of endogenous neurotransmitters and related compounds by liquid chromatography coupled to tandem mass spectrometry.Eulàlia Olesti et al.Talanta, 192, 93-102 (2018-10-24) Stimulating muscarinic M1 receptors in the anterior cingulate cortex reduces mechanical hypersensitivity via GABAergic transmission in nerve injury rats.Kohei Koga et al.Brain research, 1704, 187-195 (2018-10-20) Probing the structure of the uncoupled nicotinic acetylcholine receptor.Jiayin Sun et al.Biochimica et biophysica acta, 1859(2), 146-154 (2016-11-23) Hwangryunhaedok-Tang Exerts Neuropreventive Effect on Memory Impairment by Reducing Cholinergic System Dysfunction and Inflammatory Response in a Vascular Dementia Rat Model.Eunjin Sohn et al.Molecules (Basel, Switzerland), 24(2) (2019-01-24) The E Loop of the Transmitter Binding Site Is a Key Determinant of the Modulatory Effects of Physostigmine on Neuronal Nicotinic α4β2 Receptors.Xiaochun Jin et al.Molecular pharmacology, 91(2), 100-109 (2016-11-30) Aortic Response to Strength Training and Spirulina platensis Dependent on Nitric Oxide and Antioxidants.Aline de Freitas Brito et al.Frontiers in physiology, 9, 1522-1522 (2018-11-16) Role of nitric oxide synthase isoforms for ophthalmic artery reactivity in mice.Panagiotis Laspas et al.Experimental eye research, 127, 1-8 (2014-07-16) Matrix metalloproteinases are possible targets in monocrotaline-induced pulmonary hypertension: investigation of anti-remodeling effects of alagebrium and everolimus.Özlem Atlı et al.Anatolian journal of cardiology, 17(1), 8-17 (2016-05-18) Role of canonical transient receptor potential channel-3 in acetylcholine-induced mouse airway smooth muscle cell proliferation.Xiao-Xu Chen et al.Life sciences, 187, 64-73 (2017-08-15) Multi-Protection of DL0410 in Ameliorating Cognitive Defects in D-Galactose Induced Aging Mice.Wenwen Lian et al.Frontiers in aging neuroscience, 9, 409-409 (2017-12-26) Molecular Signatures of Reduced Nerve Toxicity by CeCl3 in Phoxim-exposed Silkworm Brains.Binbin Wang et al.Scientific reports, 5, 12761-12761 (2015-08-01) Effects of temperature on activities of antioxidant enzymes and Na+/K+-ATPase, and hormone levels in Schizothorax prenanti.Song Yang et al.Journal of thermal biology, 72, 155-160 (2018-03-03) Transplantation of a Human Tissue-Engineered Bowel in an Athymic Rat Model.Elie Zakhem et al.Tissue engineering. Part C, Methods, 23(11), 652-660 (2017-06-28) Perturbation of chemical coupling by an endothelial Cx40 mutant attenuates endothelium-dependent vasodilation by KCa channels and elevates blood pressure in mice.Daniel J Chaston et al.Pflugers Archiv : European journal of physiology, 467(9), 1997-2009 (2014-11-06) Canonical and Novel Non-Canonical Cholinergic Agonists Inhibit ATP-Induced Release of Monocytic Interleukin-1β via Different Combinations of Nicotinic Acetylcholine Receptor Subunits α7, α9 and α10.Anna Zakrzewicz et al.Frontiers in cellular neuroscience, 11, 189-189 (2017-07-21) Vasodilation and Antihypertensive Activities of Swietenia macrophylla (Mahogany) Seed Extract.Yung Sing Ch'ng et al.Journal of medicinal food, 21(3), 289-301 (2018-02-09) Apple polyphenol relieves hypoxia-induced pulmonary arterial hypertension via pulmonary endothelium protection and smooth muscle relaxation: In vivo and in vitro studies.Chunyan Hua et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 107, 937-944 (2018-09-28) Cholinergic left-right asymmetry in the habenulo-interpeduncular pathway.Elim Hong et al.Proceedings of the National Academy of Sciences of the United States of America, 110(52), 21171-21176 (2013-12-12) Alpha7 Nicotinic Acetylcholine Receptors Play a Predominant Role in the Cholinergic Potentiation of N-Methyl-D-Aspartate Evoked Firing Responses of Hippocampal CA1 Pyramidal Cells.Zsolt K Bali et al.Frontiers in cellular neuroscience, 11, 271-271 (2017-09-21) Non-competitive Inhibition of Nicotinic Acetylcholine Receptors by Ladybird Beetle Alkaloids.Ron L Leong et al.Neurochemical research, 40(10), 2078-2086 (2014-11-06) Anti-Alzheimer's disease potential of coumarins from Angelica decursiva and Artemisia capillaris and structure-activity analysis.Md Yousof Ali et al.Asian Pacific journal of tropical medicine, 9(2), 103-111 (2016-02-28) Voluntary wheel running prevents salt-induced endothelial dysfunction: role of oxidative stress.John J Guers et al.Journal of applied physiology (Bethesda, Md. : 1985), 126(2), 502-510 (2018-12-21) Vascular structure and function in the medial collateral ligament of anterior cruciate ligament transected rabbit knees.Daniel Miller et al.Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 32(9), 1104-1110 (2014-06-10) A Genetically Encoded Fluorescent Sensor Enables Rapid and Specific Detection of Dopamine in Flies, Fish, and Mice.Fangmiao Sun et al.Cell, 174(2), 481-496 (2018-07-17) Effects of Dietary Supplementation with Brazil Nuts on Microvascular Endothelial Function in Hypertensive and Dyslipidemic Patients: A Randomized Crossover Placebo-Controlled Trial.Grazielle V B Huguenin et al.Microcirculation (New York, N.Y. : 1994), 22(8), 687-699 (2015-07-28) Mechanisms Underlying the Strong Inhibition of Muscle-Type Nicotinic Receptors by Tetracaine.Raúl Cobo et al.Frontiers in molecular neuroscience, 11, 193-193 (2018-08-24) Microvascular Function and Endothelial Progenitor Cells in Patients with Severe Hypercholesterolemia and the Familial Hypercholesterolemia Phenotype.Andrea De Lorenzo et al.Cardiology, 137(4), 231-236 (2017-05-04) Isoform-specific mechanisms of α3β4*-nicotinic acetylcholine receptor modulation by the prototoxin lynx1.Andrew A George et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 31(4), 1398-1420 (2017-01-20) Low Variability in Peak Expiratory Flow Predicts Successful Inhaled Corticosteroid Step-Down in Adults with Asthma.Naomi Tsurikisawa et al.The journal of allergy and clinical immunology. In practice, 6(3), 972-979 (2017-12-10) An important role for A20-binding inhibitor of nuclear factor-kB-1 (ABIN1) in inflammation-mediated endothelial dysfunction: an in vivo study in ABIN1 (D485N) mice.Naveed Akbar et al.Arthritis research & therapy, 17, 22-22 (2015-02-05) Acetylcholine induces fibrogenic effects via M2/M3 acetylcholine receptors in non-alcoholic steatohepatitis and in primary human hepatic stellate cells.Maelle L Morgan et al.Journal of gastroenterology and hepatology, 31(2), 475-483 (2015-08-14)

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