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Peer-Reviewed Papers

Swainsonine, an alpha-mannosidase inhibitor, may worsen cervical cancer progression through the increase in myeloid derived suppressor cells population.Caio Raony Farina Silveira et al.PloS one, 14(3), e0213184-e0213184 (2019-03-07) The potential importance of swainsonine in therapy for cancers and immunology.K Olden et al.Pharmacology & therapeutics, 50(3), 285-290 (1991-01-01) Seasonal changes in Undifilum colonization and swainsonine content of locoweeds.Jorge Achata Böttger et al.Journal of chemical ecology, 38(5), 486-495 (2012-05-01) Production, HPLC analysis, and in situ apoptotic activities of swainsonine toward lepidopteran, Sf-21 cell line.Digar Singh et al.Biotechnology progress, 30(5), 1196-1205 (2014-07-22) Exposure to swainsonine impairs adult neurogenesis and spatial learning and memoryWang J, et al. Toxicology Letters, 232(1), 263-270 (2015) Swainsonine biosynthesis genes in diverse symbiotic and pathogenic fungiCook D, et al. G3 (Bethesda, Md.), 7(6), 1791-1797 (2017) Identification of a new locoweed (Oxytropis serioopetala) and its clinical and pathological features in poisoned rabbits.Qin-Fan Li et al.The Journal of veterinary medical science, 74(8), 989-993 (2012-03-27) Suppression of cancer progression by MGAT1 shRNA knockdown.Reza Beheshti Zavareh et al.PloS one, 7(9), e43721-e43721 (2012-09-08) The involvement of slaframine and swainsonine in slobbers syndrome: a review.W J Croom et al.Journal of animal science, 73(5), 1499-1508 (1995-05-01) Locoweed dose responses to nitrogen: Positive for biomass and primary physiology, but inconsistent for an alkaloid.Kevin J Delaney et al.American journal of botany, 98(12), 1956-1965 (2011-12-02) Influence of endophyte genotype on swainsonine concentrations in Oxytropis sericea.Daniel Cook et al.Toxicon : official journal of the International Society on Toxinology, 61, 105-111 (2012-11-15) The indolizidine alkaloids, slaframine and swainsonine: contaminants in animal forages.H P Broquist Annual review of nutrition, 5, 391-409 (1985-01-01) Influence of seed endophyte amounts on swainsonine concentrations in Astragalus and Oxytropis locoweeds.Daniel S Grum et al.Journal of agricultural and food chemistry, 60(33), 8083-8089 (2012-08-01) Structural basis for diverse N-glycan recognition by HIV-1-neutralizing V1-V2-directed antibody PG16.Marie Pancera et al.Nature structural & molecular biology, 20(7), 804-813 (2013-05-28) A simple and sensitive HPLC-UV method for the determination of swainsonine in rat plasma and its application in a pharmacokinetic study.D-L Li et al.Arzneimittel-Forschung, 62(5), 209-212 (2012-01-31) Swainsonine promotes apoptosis in human oesophageal squamous cell carcinoma cells in vitro and in vivo through activation of mitochondrial pathway.Zhaocal Li et al.Journal of biosciences, 37(6), 1005-1016 (2012-11-16) Isolation of natural products by ion-exchange methods.Klaus Dragull et al.Methods in molecular biology (Clifton, N.J.), 864, 189-219 (2012-03-01) [A review of the study on swainsonine--toxic elements of locoweed].Y Shi et al.Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 22(1), 47-49 (2003-08-02) Use of antiadhesive peptide and swainsonine to inhibit metastasis.K Olden et al.Annals of the New York Academy of Sciences, 551, 421-441 (1988-01-01) Swainsonine as a lysosomal toxin affects dopaminergic neurons.Qinfan Li et al.Journal of neural transmission (Vienna, Austria : 1996), 119(12), 1483-1490 (2012-06-26) A short, organocatalytic formal synthesis of (-)-swainsonine and related alkaloids.Vijay Dhand et al.Organic letters, 15(8), 1914-1917 (2013-04-05) Synthesis from D-altrose of (5R,6R,7R,8S)-5,7-dihydroxy-8-hydroxymethylconidine and 2,4-dideoxy-2,4-imino-D-glucitol, azetidine analogues of swainsonine and 1,4-dideoxy-1,4-imino-D-mannitol.Noelia Araújo et al.Organic letters, 14(16), 4174-4177 (2012-07-31) Swainsonine inhibits growth and potentiates the cytotoxic effect of paclitaxel in hepatocellular carcinoma in vitro and in vivo.Nan You et al.Oncology reports, 28(6), 2091-2100 (2012-09-21) Determination of swainsonine in the endophytic Undifilum fungi by high-performance liquid chromatography with evaporative light-scattering detector.Guo-Dong Yang et al.Toxicon : official journal of the International Society on Toxinology, 60(1), 44-49 (2012-04-10) Alpha-mannosidosis in goats caused by the swainsonine-containing plant Ipomoea verbascoidea.Fábio S Mendonça et al.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, 24(1), 90-95 (2012-03-01) Swainsonine activates mitochondria-mediated apoptotic pathway in human lung cancer A549 cells and retards the growth of lung cancer xenografts.Zhaocai Li et al.International journal of biological sciences, 8(3), 394-405 (2012-03-07) Synthesis of (-)-swainsonine and (-)-8-epi-swainsonine by the addition of allenylmetals to chiral α,β-alkoxy sulfinylimines.Julien Louvel et al.Organic letters, 13(24), 6452-6455 (2011-11-16) Potential role for saccharopine reductase in swainsonine metabolism in endophytic fungus, Undifilum oxytropis.Suman Mukherjee et al.Fungal biology, 116(8), 902-909 (2012-08-07) Alpha-mannosidase activity in stallion epididymal fluid and spermatozoa.C A Retamal et al.Theriogenology, 78(2), 252-262 (2012-05-15) Real encoded genetic algorithm and response surface methodology to optimize production of an indolizidine alkaloid, swainsonine, from Metarhizium anisopliae.Digar Singh et al.Folia microbiologica, 58(5), 393-401 (2013-01-15) N-glycan biosynthesis inhibitors induce in vitro anticancer activity in colorectal cancer cells.Julio Cesar Madureira de-Freitas-Junior et al.Journal of cellular biochemistry, 113(9), 2957-2966 (2012-05-04) Swainsonine: a new antineoplastic immunomodulator.S Mohla et al.Journal of the National Medical Association, 81(10), 1049-1056 (1989-10-01) A divergent approach to 3-piperidinols: a concise syntheses of (+)-swainsonine and access to the 1-substituted quinolizidine skeleton.Glenn Archibald et al.The Journal of organic chemistry, 77(18), 7968-7980 (2012-08-16) Influence of phenological stage on swainsonine and endophyte concentrations in Oxytropis sericea.Daniel Cook et al.Journal of chemical ecology, 38(2), 195-203 (2012-01-28) The good and the bad of poisonous plants: an introduction to the USDA-ARS Poisonous Plant Research Laboratory.Kevin D Welch et al.Journal of medical toxicology : official journal of the American College of Medical Toxicology, 8(2), 153-159 (2012-03-01) Evolution of cross-neutralizing antibody specificities to the CD4-BS and the carbohydrate cloak of the HIV Env in an HIV-1-infected subject.Iliyana Mikell et al.PloS one, 7(11), e49610-e49610 (2012-11-16) Optimization of different process variables for the production of an indolizidine alkaloid, swainsonine from Metarhizium anisopliae.Digar Singh et al.Journal of basic microbiology, 52(5), 590-597 (2011-12-07) Swainsonine, an alpha-mannosidase inhibitor, may worsen cervical cancer progression through the increase in myeloid derived suppressor cells populationSilveiraCRF, et al. PLoS ONE, 14(3), e0213184-e0213184 (2019) N-glycosylation by N-acetylglucosaminyltransferase V enhances the interaction of CD147/basigin with integrin beta1 and promotes HCC metastasisCui J, et al. The Journal of Pathology, 245(1), 41-52 (2018) Production of the alkaloid swainsonine by a fungal endophyte in the host Swainsona canescens.Daniel S Grum et al.Journal of natural products, 76(10), 1984-1988 (2013-09-24)

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