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5-Fluoro-2-methylpyrimidine-4,6-diol | CAS:1598-63-6
5-Fluoro-2-methylpyrimidine-4,6-diol
  • Name:5-Fluoro-2-methylpyrimidine-4,6-diol
  • CAS:1598-63-6
  • Synonyms:5-Fluoro-4,6-dihydroxy-2-methylpyrimidine; NSC 33038
  • Molecular Formula:C5H5FN2O2
  • Molecular Weight:144.10
  • EINESC:

Description

Properties

Melting point >310 ºC**
Density 1.59±0.1 g/cm3 (20 ºC

Safety

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SDS

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Articles
Peer-Reviewed Papers
Usnic acid inhibits biofilm formation and virulent morphological traits of Candida albicans.Nithyanand P, et al. Microbiological research, 179, 20-28 (2015) Antibacterial activity of lichen secondary metabolite usnic acid is primarily caused by inhibition of RNA and DNA synthesis.Maciag-Dorszynska M, et al. FEMS Microbiology Letters, 353(1), 57-62 (2014) Identification of Novel Inhibitors of Auxin-Induced Ca2+ Signaling via a Plant-Based Chemical Screen.Kjell De Vriese et al.Plant physiology, 180(1), 480-496 (2019-02-10) The role of autophagy in usnic acid-induced toxicity in hepatic cells.Si Chen et al.Toxicological sciences : an official journal of the Society of Toxicology, 142(1), 33-44 (2014-08-01) Usnic acid, a lichen secondary metabolite inhibits Group A Streptococcus biofilms.Nithyanand P, et al. Antonie van Leeuwenhoek, 107(1), 263-272 (2015) Usnic acid improves memory impairment after cerebral ischemia/reperfusion injuries by anti-neuroinflammatory, anti-oxidant, and anti-apoptotic properties.Sohaila Erfani et al.Iranian journal of basic medical sciences, 23(9), 1225-1231 (2020-09-24) Usnic acid induces apoptosis in human gastric cancer cells through ROS generation and DNA damage and causes up-regulation of DNA-PKcs and γ-H2A.X phosphorylation.Kunal Kumar et al.Chemico-biological interactions, 315, 108898-108898 (2019-11-13) Inhibitory Activity of (+)-Usnic Acid against Non-Small Cell Lung Cancer Cell Motility.Yang Y, et al. PLoS ONE, 11(1), e0146575-e0146575 (2016) l-arginine protects against oxidative damage induced by T-2 toxin in mouse Leydig cells.Jian Ying Yang et al.Journal of biochemical and molecular toxicology, 32(10), e22209-e22209 (2018-08-10) Proton-shuttling lichen compound usnic acid affects mitochondrial and lysosomal function in cancer cells.Margret Bessadottir et al.PloS one, 7(12), e51296-e51296 (2012-12-12) Overcoming deterrent metabolites by gaining essential nutrients: A lichen/snail case study.Alice Gadea et al.Phytochemistry, 164, 86-93 (2019-05-19)
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