Boiling point	88.6-89.2 ºC (5 Torr)**
Flash point	121.2±27.3 ºC, 计算值*
Density	1.603±0.06 g/cm3 (20 º

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Source	SDS/MSDS Samples
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Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

Separation and characterization of silybin, isosilybin, silydianin and silychristin in milk thistle extract by liquid chromatography-electrospray tandem mass spectrometry.James I Lee et al.Journal of chromatography. A, 1116(1-2), 57-68 (2006-04-25) Analysis and comparison of active constituents in commercial standardized silymarin extracts by liquid chromatography-electrospray ionization mass spectrometry.James I Lee et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 845(1), 95-103 (2006-09-01) [Silymarin in the treatment of chronic liver diseases: past and future].János Fehér et al.Orvosi hetilap, 149(51), 2413-2418 (2008-12-17) Identifying the differential effects of silymarin constituents on cell growth and cell cycle regulatory molecules in human prostate cancer cells.Gagan Deep et al.International journal of cancer, 123(1), 41-50 (2008-04-26) Influence of exogenous salicylic acid on flavonolignans and lipoxygenase activity in the hairy root cultures of Silybum marianum.Masumeh Khalili et al.Cell biology international, 33(9), 988-994 (2009-06-16) Silybin and silydianin diminish the oxidative metabolism of human polymorphonuclear neutrophils.E Ignatowicz et al.Acta biochimica Polonica, 44(1), 127-129 (1997-01-01) Effect of silybin and its congeners on human liver microsomal cytochrome P450 activities.Roman Zuber et al.Phytotherapy research : PTR, 16(7), 632-638 (2002-11-01) An in vitro study of the protective effect of the flavonoid silydianin against reactive oxygen species.Małgorzata Zielińska-Przyjemska et al.Phytotherapy research : PTR, 20(2), 115-119 (2006-01-31) Topical delivery of silymarin constituents via the skin route.Chi-feng Hung et al.Acta pharmacologica Sinica, 31(1), 118-126 (2009-12-22) Effect of the flavanolignans of Silybum marianum L. on lipid peroxidation in rat liver microsomes and freshly isolated hepatocytes.E Bosisio et al.Pharmacological research, 25(2), 147-154 (1992-02-01) Inhibition of the superoxide anion release and hydrogen peroxide formation in PMNLs by flavonolignans.Z Varga et al.Phytotherapy research : PTR, 15(7), 608-612 (2001-12-18) [Bioavailability of silymarin, I: Volumes of distribution of silybin, silydianin, and silychristin from in-vitro data (author's transl)].H P Koch et al.Archiv der Pharmazie, 314(6), 515-517 (1981-06-01) Synchronized and sustained release of multiple components in silymarin from erodible glyceryl monostearate matrix system.Cheng Lu et al.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 66(2), 210-219 (2007-01-02)

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