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Screening of drugs to counteract human papillomavirus 16 E6 repression of E-cadherin expression.Zarina J D'Costa et al.Investigational new drugs, 30(6), 2236-2251 (2012-02-24) Indole-3-carbinol induces G1 cell cycle arrest and apoptosis through aryl hydrocarbon receptor in THP-1 monocytic cell lineMohammadi S, et al. Journal of Receptor and Signal Transduction Research, 37(5), 506-514 (2017) Indole-3-carbinol and prostate cancer.Fazlul H Sarkar et al.The Journal of nutrition, 134(12 Suppl), 3493S-3498S (2004-12-01) Bax translocation to mitochondria is an important event in inducing apoptotic cell death by indole-3-carbinol (I3C) treatment of breast cancer cells.Fazlul H Sarkar et al.The Journal of nutrition, 133(7 Suppl), 2434S-2439S (2003-07-04) 1 - 1. The chemistry and pharmacology of indole-3-carbinol (indole-3-methanol) and 3-(methoxymethyl)indole. [Part I].T A Broadbent et al.Current medicinal chemistry, 5(5), 337-352 (1998-10-03) Indole-3-carbinol inhibits tumorigenicity of hepatocellular carcinoma cells via suppression of microRNA-21 and upregulation of phosphatase and tensin homolog.Xinmei Wang et al.Biochimica et biophysica acta, 1853(1), 244-253 (2014-12-03) Indole-3-carbinol. A novel approach to breast cancer prevention.H L Bradlow et al.Annals of the New York Academy of Sciences, 768, 180-200 (1995-09-30) The natural chemopreventive compound indole-3-carbinol: state of the science.Eleanor G Rogan In vivo (Athens, Greece), 20(2), 221-228 (2006-04-26) The extended version of restriction analysis approach for the examination of the ability of low-molecular-weight compounds to modify DNA in a cell-free system.Dominik Kołodziejski et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 75, 118-127 (2014-12-03) Combinations of indole-3-carbinol and silibinin suppress inflammation-driven mouse lung tumorigenesis by modulating critical cell cycle regulators.Jung Min Song et al.Carcinogenesis, 36(6), 666-675 (2015-04-22) Indole-3-carbinol induction of CYP1A1, CYP1A2, and CYP3A1 activity and gene expression in rat liver under conditions of different fat content in the diet.V A Tutelyan et al.Bulletin of experimental biology and medicine, 154(2), 250-254 (2013-01-19) Targets for indole-3-carbinol in cancer prevention.Young S Kim et al.The Journal of nutritional biochemistry, 16(2), 65-73 (2005-02-01) Natural indoles, indole-3-carbinol and 3,3'-diindolymethane, inhibit T cell activation by staphylococcal enterotoxin B through epigenetic regulation involving HDAC expression.Philip B Busbee et al.Toxicology and applied pharmacology, 274(1), 7-16 (2013-11-10) 3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells.Laura M Beaver et al.Toxicology and applied pharmacology, 263(3), 345-351 (2012-07-18) Involvement of PTEN/Akt signaling and oxidative stress on indole-3-carbinol (I3C)-induced hepatocarcinogenesis in rats.Ryuichi Yamamoto et al.Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 65(6), 845-852 (2013-01-08) Chemoprevention of chemically-induced mammary carcinogenesis by indole-3-carbinol.Grubbs CJ, et al. Anticancer Research, 15(3), 709-716 (1995) A new method for rapid determination of indole-3-carbinol and its condensation products in nutraceuticals using core-shell column chromatography method.Jakub Fibigr et al.Journal of pharmaceutical and biomedical analysis, 120, 383-390 (2016-01-23) Effect of the pasteurization process on the contents of ascorbigen, indole-3-carbinol, indole-3-acetonitrile, and 3,3'-diindolylmethane in fermented cabbage.Ewa Ciska et al.Journal of agricultural and food chemistry, 60(14), 3645-3649 (2012-03-21) Indole-3-carbinol and 3-3'-diindolylmethane antiproliferative signaling pathways control cell-cycle gene transcription in human breast cancer cells by regulating promoter-Sp1 transcription factor interactions.Gary L Firestone et al.The Journal of nutrition, 133(7 Suppl), 2448S-2455S (2003-07-04) In vitro activity of glucosinolates and their degradation products against brassica-pathogenic bacteria and fungi.T Sotelo et al.Applied and environmental microbiology, 81(1), 432-440 (2014-11-02) Targeted deletion of the aryl hydrocarbon receptor in dendritic cells prevents thymic atrophy in response to dioxin.Celine A Beamer et al.Archives of toxicology, 93(2), 355-368 (2018-12-01) Indole-3-carbinol inhibits tumorigenicity of hepatocellular carcinoma cells via suppression of microRNA-21 and upregulation of phosphatase and tensin homolog.Xinmei Wang et al.Biochimica et biophysica acta, 1853(1), 244-253 (2014-12-03) Dietary AhR Ligands Regulate AhRR Expression in Intestinal Immune Cells and Intestinal Microbiota Composition.Oliver Schanz et al.International journal of molecular sciences, 21(9) (2020-05-06) Prevention and treatment of cancer with indole-3-carbinol.M S Brignall Alternative medicine review : a journal of clinical therapeutic, 6(6), 580-589 (2002-01-24) 1. The chemistry and pharmacology of indole-3-carbinol (indole-3-methanol) and 3-(methoxymethyl)indole. [Part II].T A Broadbent et al.Current medicinal chemistry, 5(6), 469-491 (1999-01-05) Indole-3-carbinol induction of CYP1A1, CYP1A2, and CYP3A1 activity and gene expression in rat liver under conditions of different fat content in the diet.V A Tutelyan et al.Bulletin of experimental biology and medicine, 154(2), 250-254 (2013-01-19) 1 - 1. The chemistry and pharmacology of indole-3-carbinol (indole-3-methanol) and 3-(methoxymethyl)indole. [Part I].T A Broadbent et al.Current medicinal chemistry, 5(5), 337-352 (1998-10-03) [The results of adjuvant therapy of juvenile recurring respiratory papillomatosis with the use of indole-3-carbinol].Iu L Soldatskiĭ et al.Vestnik otorinolaringologii, (5)(5), 47-50 (2012-02-16) Myocardial global longitudinal strain: An early indicator of cardiac interstitial fibrosis modified by spironolactone, in a unique hypertensive rat model.Catherine J Leader et al.PloS one, 14(8), e0220837-e0220837 (2019-08-14) Effects of indole-3-carbinol on steroid hormone profile and tumor progression in a mice model of canine inflammatory mammarycancer.Asunción Martín-Ruiz et al.BMC cancer, 18(1), 626-626 (2018-06-06) Interleukin-22 protects intestinal stem cells against genotoxic stress.Konrad Gronke et al.Nature, 566(7743), 249-253 (2019-02-01) The natural chemopreventive compound indole-3-carbinol: state of the science.Eleanor G Rogan In vivo (Athens, Greece), 20(2), 221-228 (2006-04-26) Indole-3-carbinol disrupts estrogen receptor-alpha dependent expression of insulin-like growth factor-1 receptor and insulin receptor substrate-1 and proliferation of human breast cancer cells.Crystal N Marconett et al.Molecular and cellular endocrinology, 363(1-2), 74-84 (2012-07-28) The extended version of restriction analysis approach for the examination of the ability of low-molecular-weight compounds to modify DNA in a cell-free system.Dominik Kołodziejski et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 75, 118-127 (2014-12-03) 3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells.Laura M Beaver et al.Toxicology and applied pharmacology, 263(3), 345-351 (2012-07-18) Indole-3-carbinol. A novel approach to breast cancer prevention.H L Bradlow et al.Annals of the New York Academy of Sciences, 768, 180-200 (1995-09-30) Combinations of indole-3-carbinol and silibinin suppress inflammation-driven mouse lung tumorigenesis by modulating critical cell cycle regulators.Jung Min Song et al.Carcinogenesis, 36(6), 666-675 (2015-04-22) Natural indoles, indole-3-carbinol and 3,3'-diindolymethane, inhibit T cell activation by staphylococcal enterotoxin B through epigenetic regulation involving HDAC expression.Philip B Busbee et al.Toxicology and applied pharmacology, 274(1), 7-16 (2013-11-10) Screening of drugs to counteract human papillomavirus 16 E6 repression of E-cadherin expression.Zarina J D'Costa et al.Investigational new drugs, 30(6), 2236-2251 (2012-02-24) Indole-3-Carbinol (I3C) enhances the sensitivity of murine breast adenocarcinoma cells to doxorubicin (DOX) through inhibition of NF-κβ, blocking angiogenesis and regulation of mitochondrial apoptotic pathway.Subhadip Hajra et al.Chemico-biological interactions, 290, 19-36 (2018-05-19) The kinetic of key phytochemical compounds of non-heading and heading leafy Brassica oleracea landraces as affected by traditional cooking methods.Elisa Giambanelli et al.Journal of the science of food and agriculture, 96(14), 4772-4784 (2016-06-15) Indole-3-carbinol prevents diet-induced obesity through modulation of multiple genes related to adipogenesis, thermogenesis or inflammation in the visceral adipose tissue of mice.Youngshim Choi et al.The Journal of nutritional biochemistry, 23(12), 1732-1739 (2012-05-10) Review. Indole-3-carbinol as a chemoprotective agent in breast and prostate cancer.H Leon Bradlow In vivo (Athens, Greece), 22(4), 441-445 (2008-08-21) Protective Effects of Indole-3-Carbinol-Loaded Poly(lactic-co-glycolic acid) Nanoparticles Against Glutamate-Induced Neurotoxicity.Ji Heun Jeong et al.Journal of nanoscience and nanotechnology, 15(10), 7922-7928 (2016-01-05) Antiangiogenic activity of indole-3-carbinol in endothelial cells stimulated with activated macrophages.Mei-Lin Wang et al.Food chemistry, 134(2), 811-820 (2012-10-31) Indole-3-carbinol and ultraviolet B induce apoptosis of human melanoma cells via down-regulation of MITF.So-Young Kim et al.Die Pharmazie, 66(12), 982-987 (2012-02-09) [Results of open multicenter study of the safety of doxazosin in combination with indigal in men with stages I-II prostatic adenoma].V N Pavlov et al.Urologiia (Moscow, Russia : 1999), (2)(2), 42-44 (2013-06-26) Development of a solid-phase extraction method with simple MEKC-UV analysis for simultaneous detection of indole metabolites in human urine after administration of indole dietary supplement.Apichai Phonchai et al.Talanta, 174, 314-319 (2017-07-26) [EGFR-dependent impact of indol-3-carbinol on radiosensitivity of lung cancer cells].Xiao Xiao et al.Zhongguo fei ai za zhi = Chinese journal of lung cancer, 15(7), 391-398 (2012-07-21) The Indole-3-carbinol cyclic tetrameric derivative CTet synergizes with cisplatin and doxorubicin in triple-negative breast cancer cell lines.Mauro De Santi et al.Anticancer research, 33(5), 1867-1872 (2013-05-07) Two likely targets for the anti-cancer effect of indole derivatives from cruciferous vegetables: PI3K/Akt/mTOR signalling pathway and the aryl hydrocarbon receptor.Ada Popolo et al.Seminars in cancer biology, 46, 132-137 (2017-06-10) Enhanced photostability, radical scavenging and antitumor activity of indole-3-carbinol-loaded rose hip oil nanocapsules.Mailine Gehrcke et al.Materials science & engineering. C, Materials for biological applications, 74, 279-286 (2017-03-04) Modulation of carcinogen metabolizing cytochromes P450 in rat liver and kidney by cabbage and sauerkraut juices: comparison with the effects of indole-3-carbinol and phenethyl isothiocyanate.Hanna Szaefer et al.Phytotherapy research : PTR, 26(8), 1148-1155 (2011-12-17) Impact of structural differences in carcinopreventive agents indole-3-carbinol and 3,3'-diindolylmethane on biological activity. An X-ray, ¹H-¹⁴N NQDR, ¹³C CP/MAS NMR, and periodic hybrid DFT study.Jolanta Natalia Latosińska et al.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 77, 141-153 (2015-06-13) Intestinal lymphangiectasis and lipidosis in rats following subchronic exposure to indole-3-carbinol via oral gavage.Michael C Boyle et al.Toxicologic pathology, 40(4), 561-576 (2012-02-14) Profiling the hepatic effects of flutamide in rats: a microarray comparison with classical aryl hydrocarbon receptor ligands and atypical CYP1A inducersCoe KJ, et al. Drug Metabolism and Disposition, 34(7), 1266-1275 (2006) Indole-3-carbinol is a negative regulator of estrogen.Karen J Auborn et al.The Journal of nutrition, 133(7 Suppl), 2470S-2475S (2003-07-04) The use of selected phytochemicals with EDTA against Escherichia coli and Staphylococcus epidermidis single- and dual-species biofilms.J Vale et al.Letters in applied microbiology, 68(4), 313-320 (2019-02-23) Esrat Jahan Rupa et al.Materials (Basel, Switzerland), 13(14) (2020-07-28)Dendropanax morbifera is a versatile plant that has been used as a herbal medicine due to its various useful medicinal effects. To protect its active component from biological stress and increase its drug efficacy as well as drug bioavailability, nanoemulsion... Aryl Hydrocarbon Receptor Controls Monocyte Differentiation into Dendritic Cells versus Macrophages.Christel Goudot et al.Immunity, 47(3), 582-596 (2017-09-21) Molecular targets and anticancer potential of indole-3-carbinol and its derivatives.Bharat B Aggarwal et al.Cell cycle (Georgetown, Tex.), 4(9), 1201-1215 (2005-08-06) PLGA encapsulation and radioiodination of indole-3-carbinol: investigation of anticancerogenic effects against MCF7, Caco2 and PC3 cells by in vitro assaysYildiz G, et al. J. Radioanal. Nucl. Chem., 311(2), 1043-1052 (2017) Putative mechanisms of action for indole-3-carbinol in the prevention of colorectal cancer.Daniel R McGrath et al.Expert opinion on therapeutic targets, 12(6), 729-738 (2008-05-16) Mixed-species biofilms in the food industry: Current knowledge and novel control strategies.Lei Yuan et al.Critical reviews in food science and nutrition, 60(13), 2277-2293 (2019-07-02) Insight into the relationship between aryl-hydrocarbon receptor and β-catenin in human colon cancer cells.Kazuhiro Shiizaki et al.PloS one, 14(11), e0224613-e0224613 (2019-11-02) Differential modulation of dibenzo[def,p]chrysene transplacental carcinogenesis: maternal diets rich in indole-3-carbinol versus sulforaphane.Lyndsey E Shorey et al.Toxicology and applied pharmacology, 270(1), 60-69 (2013-04-10) Indole-3-carbinol. Monograph. Alternative medicine review : a journal of clinical therapeutic, 10(4), 337-342 (2005-12-22) Mechanisms Underlying Biological Effects of Cruciferous Glucosinolate-Derived Isothiocyanates/Indoles: A Focus on Metabolic Syndrome.Montserrat Esteve Frontiers in nutrition, 7, 111-111 (2020-09-29) Protective effect of Indole-3-carbinol, an NF-κB inhibitor in experimental paradigm of Parkinson's disease: In silico and in vivo studies.Neerja Saini et al.Brain, behavior, and immunity, 90, 108-137 (2020-08-18) Enhancement of carcinogenesis by the natural anticarcinogen indole-3-carbinol.G S Bailey et al.Journal of the National Cancer Institute, 78(5), 931-934 (1987-05-01) Indole-3-carbinol: anticarcinogen or tumor promoter in brassica vegetables?R H Dashwood Chemico-biological interactions, 110(1-2), 1-5 (1998-05-05) Inhibitor screening assay for neurexin-LRRTM adhesion protein interaction involved in synaptic maintenance and neurological disorders.Sudeep Karki et al.Analytical biochemistry, 587, 113463-113463 (2019-10-02) Indole-3-carbinol blocks platelet-derived growth factor-stimulated vascular smooth muscle cell function and reduces neointima formation in vivo.Hongjing Guan et al.The Journal of nutritional biochemistry, 24(1), 62-69 (2012-07-13) Direct interactions between intestinal immune cells and the diet.Marc Veldhoen Cell cycle (Georgetown, Tex.), 11(3), 426-427 (2012-01-21) Indole-3-carbinol synergistically sensitises ovarian cancer cells to bortezomib treatment.B Taylor-Harding et al.British journal of cancer, 106(2), 333-343 (2011-12-15) Pharmacological exploitation of indole-3-carbinol to develop potent antitumor agents.Jing-Ru Weng et al.Mini reviews in medicinal chemistry, 10(5), 398-404 (2010-04-08) Inhibition of oncogenic BRAF activity by indole-3-carbinol disrupts microphthalmia-associated transcription factor expression and arrests melanoma cell proliferation.Aishwarya Kundu et al.Molecular carcinogenesis, 56(1), 49-61 (2016-02-16) Adjuvant therapy for laryngeal papillomatosis.Irena Hočevar Boltežar et al.Acta dermatovenerologica Alpina, Pannonica, et Adriatica, 20(3), 175-180 (2011-12-02) Multifunctional aspects of the action of indole-3-carbinol as an antitumor agent.H L Bradlow et al.Annals of the New York Academy of Sciences, 889, 204-213 (2000-02-11) Indole-3-carbinol as a chemopreventive and anti-cancer agent.Jing-Ru Weng et al.Cancer letters, 262(2), 153-163 (2008-03-04) Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: comparisons with 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin.Bjeldanes LF, et al. Proceedings of the National Academy of Sciences of the USA, 88(21), 9543-9547 (1991) The anticarcinogen 3,3'-diindolylmethane is an inhibitor of cytochrome P-450.D M Stresser et al.Journal of biochemical toxicology, 10(4), 191-201 (1995-08-01) Hyperglycemia and renin-dependent hypertension synergize to model diabetic nephropathy.Bryan R Conway et al.Journal of the American Society of Nephrology : JASN, 23(3), 405-411 (2011-12-24)

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