Melting point	40-45 ºC
Boiling point	208-209 ºC
Flash point	103 ºC

Symbol(GHS)	T
Hazard Codes	R24/25;R36/37/38
SDS/MSDS	S26;S28A;S37/39;S45

Source	SDS/MSDS Samples
Alfa-Aesar	View & Download
Sigma-Aldrich	View & Download
TCI	View & Download

Synthetic Route

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Articles

Peer-Reviewed Papers

[Synthesis and anti-tumor activity of paeonol and its derivatives].Xue-Jun Wang et al.Yao xue xue bao = Acta pharmaceutica Sinica, 47(1), 72-76 (2012-04-12) Effect of paeonol on antioxidant and immune regulatory activity in hepatocellular carcinoma rats.Bendong Chen et al.Molecules (Basel, Switzerland), 17(4), 4672-4683 (2012-04-24) Transdermal delivery of paeonol using cubic gel and microemulsion gel.Maofu Luo et al.International journal of nanomedicine, 6, 1603-1610 (2011-09-10) The radiosensitizing effect of Paeonol on lung adenocarcinoma by augmentation of radiation-induced apoptosis and inhibition of the PI3K/Akt pathway.Yu Lei et al.International journal of radiation biology, 89(12), 1079-1086 (2013-07-24) Influence of co-administered danshensu on pharmacokinetic fate and tissue distribution of paeonol in rats.Hua Li et al.Planta medica, 78(2), 135-140 (2011-10-12) Paeonol from Hippocampus kuda Bleeler suppressed the neuro-inflammatory responses in vitro via NF-κB and MAPK signaling pathways.S W A Himaya et al.Toxicology in vitro : an international journal published in association with BIBRA, 26(6), 878-887 (2012-05-01) Paeonol suppresses oxidized low-density lipoprotein induced endothelial cell apoptosis via activation of LOX-1/p38MAPK/NF-κB pathway.Mei-Hua Bao et al.Journal of ethnopharmacology, 146(2), 543-551 (2013-01-30) Isolation and identification of the metabolites of paeonol in human urine.Liqin Ding et al.Xenobiotica; the fate of foreign compounds in biological systems, 42(12), 1206-1212 (2012-06-12) Bioactive metabolites from biotransformation of paeonol by the white-rot basidiomycete Coriolus versicolor.Xiao-Jun Li et al.Natural product communications, 6(8), 1129-1130 (2011-09-20) Cardioprotective effect of paeonol and danshensu combination on isoproterenol-induced myocardial injury in rats.Hua Li et al.PloS one, 7(11), e48872-e48872 (2012-11-10) [Study on effect of different processing methods on seven main chemical components of wild and cultivated Paeonia lactiflora].Qiuling Wang et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(7), 920-924 (2012-07-17) Inhibitory effects of salidroside and paeonol on tyrosinase activity and melanin synthesis in mouse B16F10 melanoma cells and ultraviolet B-induced pigmentation in guinea pig skin.Li-Hua Peng et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 20(12), 1082-1087 (2013-06-12) Paeonol attenuates microglia-mediated inflammation and oxidative stress-induced neurotoxicity in rat primary microglia and cortical neurons.Yu-Ting Tseng et al.Shock (Augusta, Ga.), 37(3), 312-318 (2011-11-18) The joint action of destruxins and botanical insecticides (rotenone, azadirachtin and paeonolum) against the cotton aphid, Aphis gossypii Glover.Fei Yi et al.Molecules (Basel, Switzerland), 17(6), 7533-7542 (2012-06-20) Quality control of modified xiaoyao san through the determination of 22 active components by ultra-performance liquid chromatography.Feng Qin et al.Journal of AOAC International, 94(6), 1778-1784 (2012-02-11) Paeonol Inhibits Pancreatic Cancer Cell Migration and Invasion Through the Inhibition of TGF-β1/Smad Signaling and Epithelial-Mesenchymal-Transition.Chien-Shan Cheng et al.Cancer management and research, 12, 641-651 (2020-02-27) Paeonol inhibits oxidized low density lipoprotein-induced monocyte adhesion to vascular endothelial cells by inhibiting the mitogen activated protein kinase pathway.Yue-Qin Wang et al.Biological & pharmaceutical bulletin, 35(5), 767-772 (2012-06-13) Competitive molecular interaction among paeonol-loaded liposomes: differential scanning calorimetry and synchrotron X-ray diffraction studies.Rui-guang Wu et al.International journal of pharmaceutics, 438(1-2), 91-97 (2012-09-18) [The preparation of paeonol transdermal delivery systems based on the microemulsion-based gels and its pharmacokinetics characters].Ji-Yong Liu et al.Yao xue xue bao = Acta pharmaceutica Sinica, 47(2), 244-249 (2012-04-19) [Study on stability and cutaneous permeation kinetics in vitro of positive-ionized liposome gel containing paeonol].Jun Shi et al.Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 35(5), 803-807 (2012-12-12) [Study on the influence of the contents of paeonol in the cutting process of fresh Cortex Moutan].Quan-Jiang Long et al.Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 35(6), 883-886 (2012-12-15) Simultaneous determination of danshensu, salvianolic acid B, and paeonol in ShuangDan oral liquid by HPLC.Hua Li et al.Journal of AOAC International, 96(1), 20-23 (2013-03-22) [Preparation of paeonol-beta-cyclodextrin inclusion complex loaded colon specific delivery tablets].Tongyan Wang et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 36(21), 2956-2959 (2012-02-09) Paeonol induces cytoprotective autophagy via blocking the Akt/mTOR pathway in ovarian cancer cells.Likun Gao et al.Cell death & disease, 10(8), 609-609 (2019-08-14) [Anti-tumor effect of tanshinone II A, tetrandrine, honokiol, curcumin, oridonin and paeonol on leukemia cell lines].Qing-qing Shan et al.Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 43(3), 362-366 (2012-07-21) Paeoniae radix reduces PDGF-stimulated hepatic stellate cell migration.Jong-Jen Kuo et al.Planta medica, 78(4), 341-348 (2012-03-09) [Protective effect of paeonol on neurotoxicity induced by Abeta1-42 and underlying mechanisms].Shu-zhi Zhong et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(17), 2603-2606 (2012-12-15) In vitro and in vivo evaluation of ibuprofen-paeonol conjugate.Dan Wu et al.Journal of controlled release : official journal of the Controlled Release Society, 152 Suppl 1, e98-100 (2011-12-27) [Treatment of premenstrual syndrome with Chinese medicine formula, baixiangdan capsule: implications for neuron viability and GABA(A) receptor modulation in rat cortex].Shiguang Sun et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 36(11), 1508-1511 (2012-07-12)

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