Melting point	299-300 ºC (dichloromethane
Density	2.138±0.06 g/cm3 (20 º

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Source	SDS/MSDS Samples
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Synthetic Route

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Name	CAS

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Articles

Peer-Reviewed Papers

Determination of Caffeine and Its Metabolites in Wastewater Treatment Plants Using Solid-Phase Extraction and Liquid Chromatography-Tandem Mass Spectrometry.Kai He et al.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 34(3), 349-354 (2018-03-13) Nuclear incorporation of [adenine 14C]NAD is altered by compounds which affect poly(ADP-ribose) formation.W A Tramontano et al.Phytochemistry, 29(1), 31-33 (1990-01-01) Cytochrome P450 isoform selectivity in human hepatic theobromine metabolism.S Gates et al.British journal of clinical pharmacology, 47(3), 299-305 (1999-04-24) 3-Methylxanthine production through biodegradation of theobromine by Aspergillus sydowii PT-2.Binxing Zhou et al.BMC microbiology, 20(1), 269-269 (2020-08-29) [Research on the separation of caffeine and its nine analogues by micellar electrokinetic capillary chromatography].Chun-xi Zhou et al.Se pu = Chinese journal of chromatography, 20(3), 233-236 (2003-01-25) Quantitation of hypoxanthine in plasma from patients with ischemic heart disease: adaption of a high-performance liquid chromatographic method.H M Himmel et al.Journal of chromatography, 568(1), 105-115 (1991-07-17) Biochemical and ultrastructural changes in rabbit sclera after treatment with 7-methylxanthine, theobromine, acetazolamide, or L-ornithine.K Trier et al.The British journal of ophthalmology, 83(12), 1370-1375 (1999-11-27) Degradation kinetics of caffeine and related methylxanthines by induced cells of Pseudomonas sp.Swati Sucharita Dash et al.Current microbiology, 55(1), 56-60 (2007-06-08) The impact of different proportions of a treated effluent on the biotransformation of selected micro-contaminants in river water microcosms.Karsten Nödler et al.International journal of environmental research and public health, 11(10), 10390-10405 (2014-10-14) Effects of adenosine A2A receptor antagonists on cocaine-induced locomotion and cocaine seeking.Nicholas S Haynes et al.Psychopharmacology, 236(2), 699-708 (2018-11-06) Isolation of a new dual-functional caffeine synthase gene encoding an enzyme for the conversion of 7-methylxanthine to caffeine from coffee (Coffea arabica L.).Kouichi Mizuno et al.FEBS letters, 534(1-3), 75-81 (2003-01-16) Novel caffeine degradation gene cluster is mega-plasmid encoded in Paraburkholderia caffeinilytica CF1.Di Sun et al.Applied microbiology and biotechnology, 104(7), 3025-3036 (2020-02-06) Effects of 7-methylxanthine on the sclera in form deprivation myopia in guinea pigs.Dongmei Cui et al.Acta ophthalmologica, 89(4), 328-334 (2009-10-29)

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