Melting point	265 ºC
Density	1.398

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In vitro evaluation of the metabolic enzymes and drug interaction potential of triapine.Anand Joshi et al.Cancer chemotherapy and pharmacology, 86(5), 633-640 (2020-09-30) In vitro evaluation of the metabolic enzymes and drug interaction potential of triapine.Anand Joshi et al.Cancer chemotherapy and pharmacology, 86(5), 633-640 (2020-09-30) 4-Phenyl-1H-imidazole (a low-temperature redetermination), 1-benzyl-1H-imidazole and 1-mesityl-1H-imidazole.David J Nielsen et al.Acta crystallographica. Section C, Crystal structure communications, 60(Pt 8), o542-o544 (2004-08-06) Supramolecular assemblies with calix[6]arenes and copper ions: from dinuclear to trinuclear linear arrangements of hydroxo-Cu(II) complexes.Guillaume Izzet et al.Inorganic chemistry, 45(3), 1069-1077 (2006-01-31) Synthesis and biochemical evaluation of a range of (4-substituted phenyl)sulfonate derivatives of 4-hydroxybenzyl imidazole-based compounds as potent inhibitors of 17alpha-hydroxylase/17,20-lyase (P45017alpha) derived from rat testicular microsomes.Caroline P Owen et al.Bioorganic & medicinal chemistry letters, 20(17), 5345-5348 (2010-08-03) Synthesis, biological evaluation, and molecular modeling of 1-benzyl-1H-imidazoles as selective inhibitors of aldosterone synthase (CYP11B2).Luc Roumen et al.Journal of medicinal chemistry, 53(4), 1712-1725 (2010-02-04) Electropolymerized Pyrrole-Based Conductive Polymeric Ionic Liquids and Their Application for Solid-Phase Microextraction.Amila M Devasurendra et al.ACS applied materials & interfaces, 9(29), 24955-24963 (2017-07-05) The fatty acid 8,11-diol synthase of Aspergillus fumigatus is inhibited by imidazole derivatives and unrelated to PpoB.Fredrik Jernerén et al.Lipids, 47(7), 707-717 (2012-05-01) Intramolecular hydrogen bonding as a determinant of the inhibitory potency of N-unsubstituted imidazole derivatives towards mammalian hemoproteins.Lionel Perrin et al.Metallomics : integrated biometal science, 1(2), 148-156 (2009-03-01) Metabolism of a disulfiram metabolite, S-methyl N,N-diethyldithiocarbamate, by flavin monooxygenase in human renal microsomes.M G Pike et al.Drug metabolism and disposition: the biological fate of chemicals, 29(2), 127-132 (2001-02-13) Convenient QSAR model for predicting the complexation of structurally diverse compounds with beta-cyclodextrins.Alfonso Pérez-Garrido et al.Bioorganic & medicinal chemistry, 17(2), 896-904 (2008-12-06) Conformational flexibility of mammalian cytochrome P450 2B4 in binding imidazole inhibitors with different ring chemistry and side chains. Solution thermodynamics and molecular modeling.B K Muralidhara et al.The Journal of biological chemistry, 281(12), 8051-8061 (2006-01-28) Thromboxane synthase suppression induces lung cancer cell apoptosis via inhibiting NF-κB.Kin Chung Leung et al.Experimental cell research, 316(20), 3468-3477 (2010-07-22) Effects of salinity on aldicarb toxicity in juvenile rainbow trout (Oncorhynchus mykiss) and striped bass (Morone saxatilis x chrysops).J Wang et al.Toxicological sciences : an official journal of the Society of Toxicology, 64(2), 200-207 (2001-11-24) Connective eccentricity index: a novel topological descriptor for predicting biological activity.S Gupta et al.Journal of molecular graphics & modelling, 18(1), 18-25 (2000-08-10) S-oxidation of S-methyl-esonarimod by flavin-containing monooxygenases in human liver microsomes.N Ohmi et al.Xenobiotica; the fate of foreign compounds in biological systems, 33(12), 1221-1231 (2004-01-27) Effects of salinity on aldicarb toxicity in juvenile rainbow trout (Oncorhynchus mykiss) and striped bass (Morone saxatilis x chrysops).J Wang et al.Toxicological sciences : an official journal of the Society of Toxicology, 64(2), 200-207 (2001-11-24) Synthesis and characterization of β-cyclodextrin functionalized ionic liquid polymer as a macroporous material for the removal of phenols and As(V).Muggundha Raoov et al.International journal of molecular sciences, 15(1), 100-119 (2013-12-25) 4-Methylcatechol, a Flavonoid Metabolite with Potent Antiplatelet Effects.Lenka Applová et al.Molecular nutrition & food research, 63(20), e1900261-e1900261 (2019-07-26) Detection of Polycyclic Aromatic Hydrocarbons in Water Samples by Annular Platform-Supported Ionic Liquid-Based Headspace Liquid-Phase Microextraction.Xiaojie Sun et al.Journal of analytical methods in chemistry, 2018, 3765682-3765682 (2018-10-27) QSAR-based solubility model for drug-like compounds.Rafael Gozalbes et al.Bioorganic & medicinal chemistry, 18(19), 7078-7084 (2010-09-03) A metabolic pathway for the prodrug nabumetone to the pharmacologically active metabolite, 6-methoxy-2-naphthylacetic acid (6-MNA) by non-cytochrome P450 enzymes.Kaori Matsumoto et al.Xenobiotica; the fate of foreign compounds in biological systems, 50(7), 783-792 (2019-12-20) Effect of cytochrome P450 inhibitors and anticonvulsants on the acute toxicity of acrylonitrile.Frederick W Benz et al.Archives of toxicology, 79(10), 610-614 (2005-05-03) Catalyst-free activation of kraft lignin in air using hydrogen sulfate ionic liquids.Tadeusz J Szalaty et al.International journal of biological macromolecules, 119, 431-437 (2018-07-29) Functional characterization and mechanistic modeling of the human cytochrome P450 enzyme CYP4A22.Pradeepraj Durairaj et al.FEBS letters, 593(16), 2214-2225 (2019-06-15) Induction of CYP1A by the N-imidazole derivative, 1-benzylimidazole.José María Navas et al.Environmental toxicology and chemistry, 22(4), 830-836 (2003-04-11) A convenient method to discriminate between cytochrome P450 enzymes and flavin-containing monooxygenases in human liver microsomes.A Grothusen et al.Archives of toxicology, 71(1-2), 64-71 (1996-01-01) N-benzylimidazole for preparation of S9 fraction with multi-induction of metabolizing enzymes in short-term genotoxicity assays.Y Mori et al.Mutagenesis, 16(6), 479-486 (2001-10-30) Downstream effects of splanchnic ischemia-reperfusion injury on renal function and eicosanoid release.P Rothenbach et al.Journal of applied physiology (Bethesda, Md. : 1985), 83(2), 530-536 (1997-08-01) Synthesis and spectroscopic studies on charge-transfer molecular complexes formed in the reaction of imidazole and 1-benzylimidazole with σ- and π-acceptors.Adel Mostafa et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 79(5), 1613-1620 (2011-07-01) Interactions of substrate and product with cytochrome P450 2B4.S Narasimhulu Biochemistry, 35(6), 1840-1847 (1996-02-13) Rapid and sensitive analysis of microcystins using ionic liquid-based in situ dispersive liquid-liquid microextraction.Honglian Yu et al.Journal of chromatography. A, 1406, 10-18 (2015-06-20) Use of MEKC for the analysis of reactant and product of Baylis-Hillman reaction.Li Qi et al.Journal of separation science, 32(9), 1480-1486 (2009-04-11) Toward prediction of alkane/water partition coefficients.Anita Toulmin et al.Journal of medicinal chemistry, 51(13), 3720-3730 (2008-06-19) Synthesis and structure-activity relationship of 1- and 2-substituted-1,2,3-triazole letrozole-based analogues as aromatase inhibitors.Jérémie Doiron et al.European journal of medicinal chemistry, 46(9), 4010-4024 (2011-06-28) Synthesis and biochemical evaluation of a range of potent benzyl imidazole-based compounds as potential inhibitors of the enzyme complex 17alpha-hydroxylase/17,20-lyase (P450(17alpha)).Caroline P Owen et al.Bioorganic & medicinal chemistry letters, 16(15), 4011-4015 (2006-06-06) Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a range of 4-substituted phenyl alkyl imidazole-based inhibitors of the enzyme complex 17alpha-hydroxylase/17,20-lyase (P450(17alpha)).Chirag H Patel et al.Bioorganic & medicinal chemistry letters, 16(18), 4752-4756 (2006-07-28) S-(1,2,2-trichlorovinyl)-L-cysteine sulfoxide, a reactive metabolite of S-(1,2,2-Trichlorovinyl)-L-cysteine formed in rat liver and kidney microsomes, is a potent nephrotoxicant.Adnan A Elfarra et al.The Journal of pharmacology and experimental therapeutics, 321(3), 1095-1101 (2007-03-10) 1-Benzylimidazole induces rat hepatic microsomal epoxide hydrolase with the elevation of its mRNA levels.J Y Cho et al.Xenobiotica; the fate of foreign compounds in biological systems, 25(8), 791-798 (1995-08-01) N-benzylimidazole carboxamides as potent, orally active stearoylCoA desaturase-1 inhibitors.Karen A Atkinson et al.Bioorganic & medicinal chemistry letters, 21(6), 1621-1625 (2011-02-18) Exploration of the diaphorase activity of neutrophil NADPH oxidase.Alexandra Poinas et al.European journal of biochemistry, 269(4), 1243-1252 (2002-02-22) Image-based high-throughput drug screening targeting the intracellular stage of Trypanosoma cruzi, the agent of Chagas' disease.Juan C Engel et al.Antimicrobial agents and chemotherapy, 54(8), 3326-3334 (2010-06-16) Efficient substrate screening and inhibitor testing of human CYP4Z1 using permeabilized recombinant fission yeast.Qi Yan et al.Biochemical pharmacology, 146, 174-187 (2017-09-28) Functional characterization and substrate specificity of a novel gene encoding zinc finger-like protein, ZfLp, in Xenopus laevis oocytes.Yasuna Kobayashi et al.The Journal of toxicological sciences, 37(4), 699-709 (2012-08-07) In vivo metabolism of aminopyrine by the larvae of the helminth Heligmosomoides polygyrus.D Kerboeuf et al.Parasitology research, 81(4), 302-304 (1995-01-01) Inhibition of antigen-induced muscle contractions by inhibitors of thromboxane pathway in rat small intestine.I Amstutz et al.Zentralblatt fur Veterinarmedizin. Reihe A, 44(6), 349-359 (1997-08-01) Rapid and sensitive analysis of polychlorinated biphenyls and acrylamide in food samples using ionic liquid-based in situ dispersive liquid-liquid microextraction coupled to headspace gas chromatography.Cheng Zhang et al.Journal of chromatography. A, 1481, 1-11 (2016-12-27) Removal of 2,4-dichlorophenol using cyclodextrin-ionic liquid polymer as a macroporous material: characterization, adsorption isotherm, kinetic study, thermodynamics.Muggundha Raoov et al.Journal of hazardous materials, 263 Pt 2, 501-516 (2013-11-16) Multi-species comparison of the mechanism of biotransformation of MeO-BDEs to OH-BDEs in fish.Fengyan Liu et al.Aquatic toxicology (Amsterdam, Netherlands), 114-115, 182-188 (2012-03-27) S-oxidation of S-methyl-esonarimod by flavin-containing monooxygenases in human liver microsomes.N Ohmi et al.Xenobiotica; the fate of foreign compounds in biological systems, 33(12), 1221-1231 (2004-01-27)

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