Boiling point	199 ºC
Flash point	71 ºC
Density	1.338
Refractive index	1.547-1.549

Symbol(GHS)	Xi;N
Hazard Codes	R36/37/38;R51/53
SDS/MSDS	S26;S61

Source	SDS/MSDS Samples
Alfa-Aesar	View & Download
Sigma-Aldrich	View & Download
TCI	View & Download

Synthetic Route

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Articles

Peer-Reviewed Papers

Study of graft copolymerization of N-maleamic acid-chitosan and butyl acrylate by gamma-ray irradiation.Meifang Huang et al.International journal of biological macromolecules, 36(1-2), 98-102 (2005-06-14) Deciphering the genetic determinants for aerobic nicotinic acid degradation: the nic cluster from Pseudomonas putida KT2440.José I Jiménez et al.Proceedings of the National Academy of Sciences of the United States of America, 105(32), 11329-11334 (2008-08-06) Novel comb-shaped PEG modification enhances the osteoclastic inhibitory effect and bone delivery of osteoprotegerin after intravenous administration in ovariectomized rats.Yoshihiro Miyaji et al.Pharmaceutical research, 29(11), 3143-3155 (2012-06-26) Complexes derived from the general copper (II)/maleamic acid/N, N', N''-chelate reaction systems: Synthetic, reactivity, structural and spectroscopic studies. Lazarou KN, et al. Polyhedron, 28(15), 3185-3192 (2009) Selective adsorption of D- and L-phenylalanine on molecularly-imprinted polymerized organogels formed using polymerizable gelator N-octadecyl maleamic acid.Shengzu Zhang et al.Journal of separation science, 31(21), 3782-3787 (2008-10-18) Structure and catalytic mechanism of nicotinate (vitamin B3) degradative enzyme maleamate amidohydrolase from Bordetella bronchiseptica RB50.Virginia A Kincaid et al.Biochemistry, 51(1), 545-554 (2012-01-05) Multi-arm PEG-maleimide conjugation intermediate characterization and hydrolysis study by a selective HPLC method.Jenny Wang et al.Journal of pharmaceutical and biomedical analysis, 164, 452-459 (2018-11-18) New 4-maleamic acid and 4-maleamide peptidyl chalcones as potential multitarget drugs for human prostate cancer.Juan Rodrigues et al.Pharmaceutical research, 28(4), 907-919 (2010-12-25) Formation of self-aggregated structures of different types in water of chiral polymerizable amphiphiles from L-tyrosine and L-phenylalanine.S Angayarkanny et al.Langmuir : the ACS journal of surfaces and colloids, 28(25), 9378-9386 (2012-06-13) Prodrugs of acyclovir--a computational approach.Rafik Karaman et al.Chemical biology & drug design, 79(5), 819-834 (2012-01-21) Hapten synthesis and development of a competitive indirect enzyme-linked immunosorbent assay for acrylamide in food samples.Jing Wu et al.Journal of agricultural and food chemistry, 62(29), 7078-7084 (2014-07-08) The bacterial oxidation of nicotinic acid.E J BEHRMAN et al.The Journal of biological chemistry, 228(2), 923-945 (1957-10-01) Maleamic and citraconamic acids, methyl esters, and imides. MEHTA NB, et al. The Journal of Organic Chemistry, 25(6), 1012-1015 (1960) PEGylation of osteoprotegerin/osteoclastogenesis inhibitory factor (OPG/OCIF) results in decreased uptake into rats and human liver.Motoko Saito-Yabe et al.The Journal of pharmacy and pharmacology, 62(8), 985-994 (2010-07-29) Synthesis and bioactivity of new phosphorodithioates derived from N-substituted maleamic esters.S A de Licastro et al.Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 104(1), 43-46 (1993-01-01) Reduction of Triatoma infestans (Hemiptera:Reduviidae) experimental populations exposed to feeding inhibitors.C V Vassena et al.Journal of medical entomology, 33(5), 823-827 (1996-09-01) Computer-assisted design for atenolol prodrugs for the use in aqueous formulations.Rafik Karaman et al.Journal of molecular modeling, 18(4), 1523-1540 (2011-07-26) N-substituted methyl maleamates as larvicidal compounds against Aedes aegypti (Diptera: Culicidae).Laura Harburguer et al.Parasitology research, 117(2), 611-615 (2018-01-01) Genomic analysis of Pseudomonas putida: genes in a genome island are crucial for nicotine degradation.Hongzhi Tang et al.Scientific reports, 2, 377-377 (2012-04-25) N-Phenyl and N-phenylalkyl-maleimides acting against Candida spp.: time-to-kill, stability, interaction with maleamic acids.Maximiliano Sortino et al.Bioorganic & medicinal chemistry, 16(1), 560-568 (2007-10-27) Iron(II)-dependent dioxygenase and N-formylamide deformylase catalyze the reactions from 5-hydroxy-2-pyridone to maleamate.Yuxiang Yao et al.Scientific reports, 3, 3235-3235 (2013-11-19) Glutathione-dependent conversion of N-ethylmaleimide to the maleamic acid by Escherichia coli: an intracellular detoxification process.D McLaggan et al.Applied and environmental microbiology, 66(4), 1393-1399 (2000-04-01)

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