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SDS/MSDS	S22;S24/25

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Randomized, double-blind, placebo-controlled, clinic-initiated, Canadian multicenter trial of topical edoxudine 3.0% cream in the treatment of recurrent genital herpes. Canadian Cooperative Study Group.S L Sacks et al.The Journal of infectious diseases, 164(4), 665-672 (1991-10-01) Structural studies of 5-ethyl-2'-deoxyuridine by selective pulse 1H DPFGSE NOE spectroscopy and PM3 calculations.L E Bailey et al.Nucleosides & nucleotides, 18(4-5), 1067-1068 (1999-08-05) 5-Ethyl-2?-deoxyuridine, a modulator of both antitumour action and pharmacokinetics of 5-fluorouracilKralovanszky J, et al. Journal of Cancer Research and Clinical Oncology, 125(12), 675-684 (1999) Synthesis and antiviral activity of 5-ethyl-5-halo-6-alkoxy-(or azido)-5,6-dihydro-2'-deoxyuridine diastereomers as potential prodrugs to 5-ethyl-2'-deoxyuridine.R Kumar et al.Archiv der Pharmazie, 330(8), 259-263 (1997-08-01) Modulation of 5-fluorouracil by 5-ethyl-2'-deoxyuridine on cell lines expressing different dihydropyrimidine dehydrogenase activities.Katona C, Timar F, Jeney A, et al. Anti-Cancer Drug Design, 10, 561-567 (1999) Pharmacokinetics and bioavailability of 5-ethyl-2'-deoxyuridine and its novel (5R,6R)-5-bromo-6-ethoxy-5,6-dihydro prodrugs in mice.A M Cheraghali et al.Drug metabolism and disposition: the biological fate of chemicals, 23(2), 223-226 (1995-02-01) High-performance liquid chromatographic analysis of 5-ethylpyrimidines and 5-methylpyrimidines in plasma.J M Joly et al.Journal of chromatography, 563(2), 392-399 (1991-02-15) 5-ethyl-2'-deoxyuridine, a modulator of both antitumour action and pharmacokinetics of 5-fluorouracil.J Kralovánszky et al.Journal of cancer research and clinical oncology, 125(12), 675-684 (1999-12-11) An in vitro study of ophthalmic antiviral agent toxicity on rabbit corneal epithelium.P S Imperia et al.Antiviral research, 9(4), 263-272 (1988-07-01) Synthesis and antiviral activity of acyclic derivatives of 5-ethyl-2'-deoxyuridine.K Keppeler et al.Archiv der Pharmazie, 319(4), 360-365 (1986-04-01) 5-Hexyl-2'-deoxyuridine blocks the cytotoxic effects of 5-fluorodeoxyuridine or deoxyadenosine in leukemia L1210 cells in culture.J G Cory et al.Cancer research, 50(15), 4552-4556 (1990-08-01) Cellular proliferation in mouse and human pancreatic islets is regulated by serpin B13 inhibition and downstream targeting of E-cadherin by cathepsin L.Chi-Wen Lo et al.Diabetologia, 62(5), 822-834 (2019-03-03) Specific phosphorylation of 5-ethyl-2'-deoxyuridine by herpes simplex virus-infected cells and incorporation into viral DNA.E De Clercq et al.The Journal of biological chemistry, 262(31), 14905-14911 (1987-11-05) Bioavailability and pharmacokinetic parameters for 5-ethyl-2'-deoxyuridine.A M Cheraghali et al.Antiviral research, 25(3-4), 259-267 (1994-12-01) Modulation of 5-fluorouracil by 5-ethyl-2'-deoxyuridine on cell lines expressing different dihydropyrimidine dehydrogenase activities.C Katona et al.Anti-cancer drugs, 10(6), 561-567 (2000-07-08) 5-Ethyl-2'-deoxyuridine: an explanation for its lack of cytotoxic action in vivo.A Jeney et al.European journal of cancer & clinical oncology, 22(5), 557-562 (1986-05-01) [Potentiation of 5-fluorouracil efficacy. Molecular mechanisms playing a role in the cytotoxic action of 5-fluorouracil and 5-ethyl-2'-deoxyuridine (EUdR) combination].Csilla Katona et al.Magyar onkologia, 48(3), 243-251 (2004-11-03) [Metabolic studies of 5-ethyl-2'-deoxyuridine with liver extract, liver cells and liver cell culture].A Buchele et al.Arzneimittel-Forschung, 39(2), 220-222 (1989-02-01) Sensitivity of monkey B virus (Cercopithecine herpesvirus 1) to antiviral drugs: role of thymidine kinase in antiviral activities of substrate analogs and acyclonucleosides.Federico Focher et al.Antimicrobial agents and chemotherapy, 51(6), 2028-2034 (2007-04-18) Elimination of the antiviral drug 5-ethyl-2'-deoxyuridine by the isolated perfused rat liver.J M Joly et al.Drug metabolism and disposition: the biological fate of chemicals, 19(6), 1058-1065 (1991-11-01) [Penetration and action of edoxudine in vitro and in vivo].R Kaul et al.Arzneimittel-Forschung, 39(3), 366-368 (1989-03-01) Antitumor cell and antimetabolic effects of 5-ethyl-2?-deoxyuridine and 5?-substituted 5-ethyl-2?-deoxyuridine derivativesBalzarini J, et al. Investigational New Drugs, 2(1), 35-47 (1984) Accumulation of 5-ethyl-2'-deoxyuridine and its 5,6-dihydro prodrugs in murine lung and its potential clinical application.A M Cheraghali et al.The Journal of pharmacy and pharmacology, 47(7), 595-600 (1995-07-01) Deoxyribosyl exchange reactions leading to the in vivo generation and regeneration of the antiviral agents (E)-5-(2-bromovinyl)-2'-deoxyuridine, 5-ethyl-2'-deoxyuridine and 5-(2-chloroethyl)-2'-deoxyuridine.C Desgranges et al.Biochemical pharmacology, 35(10), 1647-1653 (1986-05-15) Effect of ethyldeoxyuridine on 5-fluorouracil-induced neutropenia.A Megyeri et al.Acta physiologica Hungarica, 84(3), 309-310 (1996-01-01) Synthesis, biotransformation, pharmacokinetics, and antiviral properties of 5-ethyl-5-halo-6-methoxy-5,6-dihydro-2'-deoxyuridine diastereomers.A M Cheraghali et al.Biochemical pharmacology, 47(9), 1615-1625 (1994-04-29) Cellular Plasticity of Defa4Cre-Expressing Paneth Cells in Response to Notch Activation and Intestinal Injury.Jennifer C Jones et al.Cellular and molecular gastroenterology and hepatology, 7(3), 533-554 (2019-03-05) Pleiotrophin suppression of receptor protein tyrosine phosphatase-β/ζ maintains the self-renewal competence of fetal human oligodendrocyte progenitor cells.Crystal R McClain et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(43), 15066-15075 (2012-10-27) Synthesis and biodistribution of [4-14C]-5-bromo-6-methoxy-5,6-dihydro-prodrug derivatives of 5-ethyl-2'-deoxyuridine.A M Cheraghali et al.Drug design and discovery, 12(1), 53-61 (1994-07-01) Retinal toxicity of intravitreal ethyldeoxyuridine and zinc.J R Nikoleit et al.Annals of ophthalmology, 20(10), 385-387 (1988-10-01)

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