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Clotiapine | CAS:2058-52-8
Clotiapine
  • Name:Clotiapine
  • CAS:2058-52-8
  • Synonyms:2-Chloro-11-(4-methylpiperazino)dibenzo[b,f][1,4]thiazepine; Clothiapin; Clothiapine; Clotiapine; Deliton; Entumine; Etumine; HF 2159; LW 2159
  • Molecular Formula:C18H18ClN3S
  • Molecular Weight:343.87
  • EINESC:218-162-8

Description

Properties

Melting point 121-123 ºC**
Density 1.33±0.1 g/cm3 (20 ºC

Safety

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SDS

Source SDS/MSDS Samples
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Articles
Peer-Reviewed Papers
The requirement of phosphorylation on a threonine residue in the acute regulation of steroidogenesis in MA-10 mouse Leydig cells.D M Stocco et al.The Journal of steroid biochemistry and molecular biology, 46(3), 337-347 (1993-09-01) Novel parent structures for inhibitors of the murine GABA transporters mGAT3 and mGAT4.Andrea Kragler et al.European journal of pharmacology, 519(1-2), 43-47 (2005-08-23) IR low-temperature matrix, X-ray and ab initio study on L-isoserine conformations.Jan Cz Dobrowolski et al.Physical chemistry chemical physics : PCCP, 12(36), 10818-10830 (2010-07-10) Microbial resolution of 2-hydroxy-3-nitropropionic acid for synthesis of optically active isoserine.Y Yasohara et al.Bioscience, biotechnology, and biochemistry, 65(5), 1258-1260 (2001-07-07) Nitrile biotransformations for highly enantioselective synthesis of oxiranecarboxamides with tertiary and quaternary stereocenters; efficient chemoenzymatic approaches to enantiopure alpha-methylated serine and isoserine derivatives.Mei-Xiang Wang et al.The Journal of organic chemistry, 70(7), 2439-2444 (2005-03-25) Asymmetric synthesis of oxazolidine nucleosides and related chemistry.J Du et al.Nucleosides & nucleotides, 17(1-3), 1-13 (1998-08-26) A convenient enantioselective synthesis of (S)-alpha-trifluoromethylisoserine.Alberto Avenoza et al.The Journal of organic chemistry, 70(14), 5721-5724 (2005-07-02) Substituting isoserine for serine in the thrombin receptor activation peptide SFLLRN confers resistance to aminopeptidase M-induced cleavage and inactivation.B S Coller et al.The Journal of biological chemistry, 268(28), 20741-20743 (1993-10-05) Organocatalytic syn-aldol reactions of dioxanones with (S)-isoserinal hydrate: synthesis of L-deoxymannojirimycin and L-deoxyidonojirimycin.Nagarjuna Palyam et al.The Journal of organic chemistry, 74(11), 4390-4392 (2009-05-02) Glycine conjugates in a lepidopteran insect herbivore--the metabolism of benzylglucosinolate in the cabbage white butterfly, Pieris rapae.Fredd Vergara et al.Chembiochem : a European journal of chemical biology, 7(12), 1982-1989 (2006-11-07) Effects of the serine analogues isoserine and serinol on interleukin-2 synthesis and phospholipid metabolism in a human T cell line Jurkat.C Pelassy et al.Journal of lipid mediators, 3(1), 79-89 (1991-01-01) Synthesis of a novel series of L-isoserine derivatives as aminopeptidase N inhibitors.Kanghui Yang et al.Journal of enzyme inhibition and medicinal chemistry, 27(2), 302-310 (2011-07-21) Isoserine-based biotinylated photoaffinity probes that interact with penicillin-binding protein 1b.Thomas Rühl et al.Chemical communications (Cambridge, England), (15)(15), 1630-1631 (2002-08-13) Regioselective and stereoselective nucleophilic ring opening of trifluoromethylated cyclic sulfates: asymmetric synthesis of both enantiomers of syn-(3-trifluoromethyl)isoserine.Zhong-Xing Jiang et al.The Journal of organic chemistry, 69(16), 5486-5489 (2004-08-04) Probing the carbohydrate recognition domain of E-selectin: the importance of the acid orientation in sLex mimetics.Alexander Titz et al.Bioorganic & medicinal chemistry, 18(1), 19-27 (2009-12-02) Component match in rhodium catalyzed three-component reactions of ethyl diazoacetate, H2O and aryl imines: a highly diastereoselective one-step synthesis of beta-aryl isoserine derivatives.Zhenqiu Guo et al.Organic & biomolecular chemistry, 7(23), 5028-5033 (2009-11-13)
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